Neurological soft signs in obsessive compulsive disorder: standardised assessment and comparison with schizophrenia.

Abstract:

:While several studies have detected raised levels of neurological soft signs in patients with obsessive compulsive disorder (OCD), the specificity of these abnormalities remains uncertain. This study used a new standardised measure, the Cambridge Neurological Inventory (CNI), to assess soft signs in 51 subjects with OCD. Comparison was made with data on patients with schizophrenia and a non-clinical control group from a previously reported study. Individuals with OCD showed raised levels of soft signs compared with non-clinical controls in many categories of the CNI: Motor Coordination, Sensory Integration, Primitive Reflexes, Extrapyramidal Signs, and Failure of Suppression. Compared with patients with schizophrenia, the OCD group had lower levels of neurological signs in some CNI categories: Hard Signs, Motor Co-ordination, Tardive Dyskinesia, Catatonic Signs, and Extrapyramidal Signs. However, levels of soft signs in the OCD group did not significantly differ from those in the schizophrenia group in other CNI categories: Sensory Integration, Primitive Reflexes and Failure of Suppression. The significance of these patterns of findings is discussed.

journal_name

Behav Neurol

journal_title

Behavioural neurology

authors

Bolton D,Gibb W,Lees A,Raven P,Gray JA,Chen E,Shafran R

doi

10.1155/1999/639045

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

197-204

issue

4

eissn

0953-4180

issn

1875-8584

journal_volume

11

pub_type

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