Abstract:
:Cognitive impairment in multiple sclerosis is an increasingly recognized entity. This article reviews the cognitive impairment of multiple sclerosis, its prevalence, its relationship to different types of multiple sclerosis, and its contribution to long-term functional prognosis. The discussion also focuses on the key elements of cognitive dysfunction in multiple sclerosis which distinguish it from other forms of cognitive impairment. Therapeutic interventions potentially effective for the cognitive impairment of multiple sclerosis are reviewed including the effects of disease modifying therapies and the use of physical and cognitive interventions.
journal_name
Behav Neuroljournal_title
Behavioural neurologyauthors
Pierson SH,Griffith Ndoi
10.1155/2006/545860subject
Has Abstractpub_date
2006-01-01 00:00:00pages
53-67issue
1eissn
0953-4180issn
1875-8584journal_volume
17pub_type
杂志文章,评审abstract::A case of late onset sporadic startle syndrome in a patient with a right posterior fossa brain tumour is reported. The exaggerated startle response did not respond to treatment with clonazepam. In addition to anxiety and depression, the patient developed obsessive- compulsive symptoms which responded to behavioural th...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/1998/617160
更新日期:1998-01-01 00:00:00
abstract::Cognitive impairment is frequently encountered in multiple sclerosis (MS) affecting between 40-65% of individuals, irrespective of disease duration and severity of physical disability. In the present multicenter randomized controlled trial, fifty-eight clinically stable RRMS patients with mild to moderate cognitive im...
journal_title:Behavioural neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2017/5919841
更新日期:2017-01-01 00:00:00
abstract::Neuropsychological studies of memory disorders have played a prominent role in the development of theories of memory. To test and refine such theories in future, it will be advantageous to include research that utilizes physiological measures of the neural events responsible for memory. Measures of the electrical acti...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2000/865250
更新日期:2000-01-01 00:00:00
abstract::A large amount of research has been conducted on the effects of sex hormones on gender differences in patients with depression, yet research on cognitive differences between male and female patients with depression is insufficient. This study uses emotion pictures to investigate the differences of the emotional workin...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2015/807343
更新日期:2015-01-01 00:00:00
abstract::Gaining a driver's licence represents increased independence and can lead to improved quality of life for individuals and their families. Learning to drive a motor vehicle and maintaining safe on-road skills are often more difficult for people on the autism spectrum. Many countries currently have no autism-specific li...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2018/6842306
更新日期:2018-08-28 00:00:00
abstract::Communication in humans activates almost every part of the brain. Of course, the use of language predominates, but other cognitive functions such as attention, memory, emotion, and executive processes are also involved. However, in order to explain how our brain "understands," "speaks," and "writes," and in order to r...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2019/9894571
更新日期:2019-07-22 00:00:00
abstract:BACKGROUND:Tourette syndrome (TS) is a neuropsychiatric disorder with childhood onset characterized by chronic motor and vocal tics. The typical clinical course of an attenuation of symptoms during adolescence in parallel with the emerging self-regulatory control during development suggests that plastic processes may p...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.3233/BEN-120294
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Poststroke depression (PSD) is a common complication after stroke. There is no adequate treatment for PSD. This study examined efficacy of cognitive rehabilitation therapy (CRT) in the treatment of PSD among stroke survivors. METHODS:An experimental design, 30 participants with poststroke depres...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2017/4058124
更新日期:2017-01-01 00:00:00
abstract::Since the very beginning of the aphasia history it has been well established that there are two major aphasic syndromes (Wernicke's-type and Broca's-type aphasia); each one of them is related to the disturbance at a specific linguistic level (lexical/semantic and grammatical) and associated with a particular brain dam...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2015/872487
更新日期:2015-01-01 00:00:00
abstract::Aiming and tapping movements were analysed repeatedly over a three-week period in a patient who was hemideafferented due to an ischaemic posterior thalamic lesion. Contrasting behaviour observed in six healthy subjects, nine hemiparetic patients and one patient with hemianopic stroke, allowed the determination of beha...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1997-10103
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Apathy and reduced emotion-based decision-making are two behavioral modifications independently described in Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI). OBJECTIVES:The aims of this study were to investigate decision-making based on emotional feedback processing in AD and aMCI and...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2014/231469
更新日期:2014-01-01 00:00:00
abstract::We report findings from a cognitive neuropsychological and psychophysiological investigation of a patient who displayed an exacerbated acute emotional expression during movement, innocuous, and aversive somatosensory stimulation. The condition developed in the context of non-specific white matter ischaemia along with ...
journal_title:Behavioural neurology
pub_type: 临床试验,杂志文章
doi:10.1155/2004/458327
更新日期:2004-01-01 00:00:00
abstract::Patients with Cushing's syndrome (CS) frequently report impairments in cognitive and emotional functioning. Given neuroimaging research that implicates alterations in structure and function in the brain in this population, goals of this study were to investigate neuropsychological and emotional functioning, with parti...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2020/4064370
更新日期:2020-08-07 00:00:00
abstract:BACKGROUND:Huntington disease (HD) is an inherited neuropsychiatric condition with progressive neurodegenerative changes, mainly affecting the striatum. Pathological processes within the striatum are likely to lead to alterations in dopamine and glutamate activity in frontostriatal circuitry, resulting in characteristi...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.3233/BEN-2012-120268
更新日期:2013-01-01 00:00:00
abstract::With the increase in the elderly, stroke has become a common disease, often leading to motor dysfunction and even permanent disability. Lower-limb rehabilitation robots can help patients to carry out reasonable and effective training to improve the motor function of paralyzed extremity. In this paper, the developments...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2017/3731802
更新日期:2017-01-01 00:00:00
abstract::A déjà vu experience is a dissociative phenomenon, which can be characterized as a subjectively inappropriate impression of familiarity of the present with an undefined past. This paper reviews empirical studies on déjà vu experiences and summarizes the most salient findings. Overall, the findings appear to be inconsi...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1992-5303
更新日期:1992-01-01 00:00:00
abstract::Patients with brain function disorders due to stroke or dementia may show inability to recognize themselves in the mirror. Although the cognitive ability to recognize mirror images has been investigated in many animal species, the animal species that can be used for experimentation and the mechanisms involved in recog...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2020/4071315
更新日期:2020-02-03 00:00:00
abstract::When assessing for the presence of hemianesthesia, the examiner touches the body of the patients, and requests that they report verbally the location of the delivered tactile stimulus. Contralesional omissions of single tactile stimuli, however, might be due to either primary somatosensory deficits or to spatial atten...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-2012-110225
更新日期:2013-01-01 00:00:00
abstract::The clinical and neuroradiological findings of three patients with marked palilalia due to different neurological disorders are reported. These cases and others in the literature suggest the possibility of different variations. "Spasmodic, heterophonic palilalia" is typically observed in Parkinson's syndrome and pseud...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1992-5407
更新日期:1992-01-01 00:00:00
abstract::The term functional amnesia (FA) has been proposed for cases of memory impairment presenting with severe retrograde amnesia in the absence of cerebral injury or history of psychiatric disturbance. Emotional flattening has often been reported alongside FA, however the mechanism of such a modification is unknown. This s...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2008/245495
更新日期:2008-01-01 00:00:00
abstract::The "psychic tonus" model or PTM [1] of hemispheric specialization states that the left hemisphere is a psychic and behavioral activator and that the right hemisphere is an inhibitor. The PTM predicts that the tonus of visual representation ought to manifest hemispheric specialization in the occipital lobes. Specifica...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2008/139436
更新日期:2008-01-01 00:00:00
abstract::Patients with unilateral neglect are impaired at making saccades to contralesional targets. Whether this problem arises from a deficit in perception, in planning the saccade or in executing the eye movement or some combination thereof remains unclear. We measured several variables related to the initiation and executi...
journal_title:Behavioural neurology
pub_type: 临床试验,杂志文章
doi:10.1155/2002/253201
更新日期:2001-01-01 00:00:00
abstract::Two experiments examined short-term memory for order information in six patients diagnosed with Parkinson's disease (PD) and six control subjects while event related potentials (ERPs) were recorded. The subjects were tested for recognition of abstract spatial designs and words after a 5 s retention interval. The PD pa...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1996-9203
更新日期:1996-01-01 00:00:00
abstract::Subjects with Alzheimer's disease (AD) show loss of cognitive functions and change in behavioral and functional state affecting the quality of their daily life and that of their families and caregivers. A neuropsychological assessment plays a crucial role in detecting such changes from normal conditions. However, desp...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2017/1850909
更新日期:2017-01-01 00:00:00
abstract::Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (r...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2006/793256
更新日期:2006-01-01 00:00:00
abstract::The present study examined the differential contribution of cortical and subcortical brain structures in emotional processing by comparing patients with focal cortical lesions (n = 32) to those with primarily subcortical dysregulation of the basal ganglia (Parkinson's disease n = 14). A standardized measure of emotion...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/1998/579029
更新日期:1998-01-01 00:00:00
abstract::Neglect behavior of experimental animals with unilateral posterior cortical lesions improves with the placement of a second lesion in the contralesional superior colliculus or in the intercollicular commissure. Given that the retinotectal fibers are mainly crossed, it has been speculated that ipsilesional eye patching...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1994-73-408
更新日期:1994-01-01 00:00:00
abstract::Understanding the mental states of others entails a number of cognitive processes known as Theory of Mind (ToM). A relationship between ToM deficits and executive disorders has been hypothesized in individuals with Parkinson's disease (PD). The present study was aimed at investigating the effect of dysexecutive defici...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-129018
更新日期:2013-01-01 00:00:00
abstract::Dementia with Lewy bodies (DLB) is the second most common degenerative dementia of the central nervous system. The technique 18F-fluorodeoxyglucose positron emission tomography (18F FDG PET) was used to investigate brain metabolism patterns in DLB patients. Conventional statistical methods did not consider intern meta...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2018/8420658
更新日期:2018-05-08 00:00:00
abstract:BACKGROUND:Tacrolimus-associated encephalopathy (TAC-E) is usually described under the term of posterior reversible encephalopathy syndrome (PRES). However, a large amount of data has suggested that TAC-E is not a homogenous entity: indeed, TAC-E which is often presented with atypical and potentially misleading imaging...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2014/931808
更新日期:2014-01-01 00:00:00