Alois Alzheimer and Gaetano Perusini: should man divide what fate united?

Abstract:

:Three points of interest lie in considering how Alzheimer, and more significantly Perusini, struggled to throw light on the cause of this devastating disease. There is a stimulating possibility that Perusini believed presenile forms of Alzheimer's disease described the same disease as senile forms. If so this would anticipate current opinion, and reveal Perusini to dissent from Kraepelin. In addition, Perusini may have understood the pathological relationship between neuritic plaques and vascular changes, once more foreseeing the modern view of Alzheimer's disease. Finally, Perusini and Alzheimer disagreed with Jung's view concerning the relationship between neuropathology and clinical psychiatry. This point highlights the major change occurring at that time from classical neurology to the psychoanalytic era. In his last work (1911) Alzheimer quoted his Italian disciple many times, even speaking of 'Perusini's cases' (Perusinischen Fälle). This article is an attempt to change the eponym of Alzheimer's disease into the Alzheimer-Perusini disease. This is a brief history of a master and his disciple, whose scientific lives were, by events, divided.

journal_name

Behav Neurol

journal_title

Behavioural neurology

authors

Macchi G,Brahe C,Pomponi M

doi

10.3233/BEN-1997-10401

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

105-8

issue

4

eissn

0953-4180

issn

1875-8584

pii

UJ0G76326176109R

journal_volume

10

pub_type

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