Abstract:
OBJECTIVE:The purpose of this study was to analyze the effect of a neuropsychological rehabilitation (NR) program on patients with Alzheimer's disease (AD). METHODS:The sample was composed of 16 elderly outpatients who participated in an open trial with rivastigmine (6 to 12 mg/day) for 4 months and were randomized to 3 different groups: 1. group NR (N=5), 2. individualized NR (N=6) and 3. NR at home under supervision of a relative or caregiver (N=5). All 3 groups fulfilled the same NR protocol consisting of a once a week session. Just before and after the 22 week period of rehabilitation, all patients were evaluated using psychiatric and functional scales, and neuropsychological tests by interviewers that did not participate in the cognitive training. RESULTS:The intervention did not produce any statistically significant change, but small gains were observed on some cognition tests, activities of daily living (ADL), and psychiatric symptoms in groups 1 and 2. CONCLUSION:Group NR is recommended for reducing psychiatric symptoms, and individualized NR for improving ADL. NR at home either has no associated benefits, or the training sessions were not appropriately conducted by the caregiver. However, additional research with larger samples is necessary to confirm these observations.
journal_name
Behav Neuroljournal_title
Behavioural neurologyauthors
Avila R,Carvalho IA,Bottino CM,Miotto ECdoi
10.1155/2007/915816subject
Has Abstractpub_date
2007-01-01 00:00:00pages
225-33issue
4eissn
0953-4180issn
1875-8584journal_volume
18pub_type
杂志文章,随机对照试验abstract::Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (r...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2006/793256
更新日期:2006-01-01 00:00:00
abstract::Cognitive impairment is frequently encountered in multiple sclerosis (MS) affecting between 40-65% of individuals, irrespective of disease duration and severity of physical disability. In the present multicenter randomized controlled trial, fifty-eight clinically stable RRMS patients with mild to moderate cognitive im...
journal_title:Behavioural neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2017/5919841
更新日期:2017-01-01 00:00:00
abstract::Two experiments examined short-term memory for order information in six patients diagnosed with Parkinson's disease (PD) and six control subjects while event related potentials (ERPs) were recorded. The subjects were tested for recognition of abstract spatial designs and words after a 5 s retention interval. The PD pa...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1996-9203
更新日期:1996-01-01 00:00:00
abstract:Aim:To identify the factors protecting Abeta-positive subjects with normal cognition (NC) or mild cognitive impairment (MCI) from conversion to Alzheimer's disease (AD). Methods:Subjects with MCI in the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, with baseline data for neuropsychological tests, brain ...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2020/7029642
更新日期:2020-10-29 00:00:00
abstract::Aberrant production of nitric oxide following inducible nitric oxide synthase (iNOS) expression has been implicated in cell death and contributes to ischemic brain injury. Tetrahydrobiopterin (BH4) is an essential cofactor of NOS activity. Herein, we evaluated antiapoptotic and anti-inflammatory effects of diamino-6-h...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2018/5050469
更新日期:2018-06-19 00:00:00
abstract::The paper examines the ability of Statistical Parametric Mapping (SPM) to contribute towards the quantitative analysis of HMPAO SPECT images containing lesions. A validation study is described in which SPECT images were created that contained synthetic lesions and were analysed with SPM. The study established a set of...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2000/681916
更新日期:2000-01-01 00:00:00
abstract:Background:Epilepsy is a chronic neurological disorder characterized by unprovoked recurrent seizure episodes. The disease has detrimental effects on social, cognitive, psychological, and physical components of life consequently quality of life of the patients. The level of the effect of the disease on quality life is ...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2018/7593573
更新日期:2018-12-02 00:00:00
abstract::We investigated social cognition and theory of mind in patients with schizophrenia and in patients with frontotemporal dementia in order to elucidate the cognitive mechanisms involved in the breakdown of these skills in psychiatric and neurological patients. Our tasks included videotaped scenarios of social interactio...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2008/157356
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To study risk factors related to ischemic stroke (IS) in youth and the influence of sleep quality on youth ischemic stroke incidence. METHODS:223 patients aged 18 to 45 years who were admitted to Puyang People's Hospital from June 2011 to February 2013 with a first-ever ischemic stroke were selected as the r...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2014/246841
更新日期:2014-01-01 00:00:00
abstract::Gaining a driver's licence represents increased independence and can lead to improved quality of life for individuals and their families. Learning to drive a motor vehicle and maintaining safe on-road skills are often more difficult for people on the autism spectrum. Many countries currently have no autism-specific li...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2018/6842306
更新日期:2018-08-28 00:00:00
abstract:Objectives:This study is aimed at elucidating the prevalence of depression in patients with myasthenia gravis (MG) and examining the risk factors associated with depression. Methods:We evaluated adult patients with MG who were recruited from two tertiary hospitals in the central region (Riyadh) of Saudi Arabia. Data w...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2019/9367453
更新日期:2019-09-15 00:00:00
abstract:BACKGROUND AND PURPOSE:Poststroke depression (PSD) is a common complication after stroke. There is no adequate treatment for PSD. This study examined efficacy of cognitive rehabilitation therapy (CRT) in the treatment of PSD among stroke survivors. METHODS:An experimental design, 30 participants with poststroke depres...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2017/4058124
更新日期:2017-01-01 00:00:00
abstract:Objective:To compare baseline and 72-hour hormone levels in women with traumatic brain injury (TBI) and controls. Setting:Hospital emergency department. Participants:21 women ages 18-35 with TBI and 21 controls. Design:Repeated measures. Main Measures:Serum samples at baseline and 72 hours; immunoassays for estradi...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2019/7694503
更新日期:2019-02-12 00:00:00
abstract::Norepinephrine and dopamine are both believed to affect signal-to-noise in the cerebral cortex. Dopaminergic agents appear to modulate semantic networks during indirect semantic priming, but do not appear to affect problem solving dependent on access to semantic networks. Noradrenergic agents, though, do affect semant...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-2009-0236
更新日期:2009-01-01 00:00:00
abstract::A case of the Gilles de la Tourette syndrome from Guyana in South America is presented. The patient had a positive family history as well as coprolalia, echolalia, and attention deficit disorder with hyperactivity. The family history and cross-cultural similarity emphasise the biological factors in the aetiology of th...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1992-5107
更新日期:1992-01-01 00:00:00
abstract::In addition to motor symptomatology, idiopathic Parkinson's disease is characterized by emotional dysfunction. Depression affects some 30 to 40 percent of Parkinson patients and other psychiatric co-morbidities include anxiety and apathy. Neuropsychological and neuroimaging studies of emotional dysfunction in Parkinso...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.3233/BEN-2011-0329
更新日期:2011-01-01 00:00:00
abstract::Introduction. Antiepileptic drugs are effective in the treatment of epilepsy to the extent that about 70% of people with epilepsy can be seizure-free, but poor adherence to medication is major problem to sustained remission and functional restoration. The aim of this study was to assess the prevalence and associated f...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2016/3189108
更新日期:2016-01-01 00:00:00
abstract::When assessing for the presence of hemianesthesia, the examiner touches the body of the patients, and requests that they report verbally the location of the delivered tactile stimulus. Contralesional omissions of single tactile stimuli, however, might be due to either primary somatosensory deficits or to spatial atten...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-2012-110225
更新日期:2013-01-01 00:00:00
abstract::Anxiety in Parkinson's disease (aPD) is underdiagnosed, undertreated, and understudied. As many as 50% of persons diagnosed with Parkinson's disease (PD) are reported to suffer from anxiety. Current treatment is largely pharmacologic, which can result in a myriad of undesirable and unsafe side effects. The aim of this...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2019/8459579
更新日期:2019-05-02 00:00:00
abstract::Traumatic brain injury (TBI) is the most common cause of long-term disability and death among young adults, and it represents an enormous socioeconomic and healthcare burden. Our purpose is to evaluate the effects of a virtual reality training with BTs-Nirvana (BTs-N) on the recovery of cognitive functions in TBI subj...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2019/9268179
更新日期:2019-07-30 00:00:00
abstract::We investigated the evolution of the neurological and neuropsychological characteristics in a right-handed woman who was 53-years-old at the onset and who showed personality changes and behavioral disorders accompanied by progressive dysarthria. She had hypernasality and a slow rate of speech with distorted consonants...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2006/320638
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Thalamic lesions are seen in a multitude of disorders including vascular diseases, metabolic disorders, inflammatory diseases, trauma, tumours, and infections. In some diseases, thalamic involvement is typical and sometimes isolated, while in other diseases thalamic lesions are observed only occasionally (of...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2014/154631
更新日期:2014-01-01 00:00:00
abstract:Objective:The aim of this study is to explore the relationship between neuron-specific enolase (NSE) gene polymorphism and delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) and provide a theoretical basis for DEACMP pathogenesis, diagnosis, and prognosis. Methods:To investigate this relationship, w...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2020/8819210
更新日期:2020-10-14 00:00:00
abstract::Neglect behavior of experimental animals with unilateral posterior cortical lesions improves with the placement of a second lesion in the contralesional superior colliculus or in the intercollicular commissure. Given that the retinotectal fibers are mainly crossed, it has been speculated that ipsilesional eye patching...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1994-73-408
更新日期:1994-01-01 00:00:00
abstract::The clinical and neuroradiological findings of three patients with marked palilalia due to different neurological disorders are reported. These cases and others in the literature suggest the possibility of different variations. "Spasmodic, heterophonic palilalia" is typically observed in Parkinson's syndrome and pseud...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1992-5407
更新日期:1992-01-01 00:00:00
abstract::Eighty-five patients with idiopathic spasmodic torticollis were compared with an equally chronic group of 49 cervical spondylosis sufferers in terms of body concept, depression, and disability. The torticollis patients were significantly more depressed and disabled and had a more negative body concept. Depression had ...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1990-3206
更新日期:1990-01-01 00:00:00
abstract::Patients with focal brain-damage, right/left hemisphere-damage (RHD/LHD) and anterior/posterior region-damage (ARD/PRD), and normal controls (NC) were asked to match photographs of top-bottom facial parts expressing different emotions, positive (happy, surprise), negative-aroused (fear, anger), negative-nonaroused (sa...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1991-4405
更新日期:1991-01-01 00:00:00
abstract::What distinguishes the recall of real-life experiences from that of self-created, fictitious emotionally laden information? Both kinds of information belong to the episodic memory system. Autobiographic memories constitute that part of the episodic memory system that is composed of significant life episodes, primarily...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2000/303651
更新日期:2000-01-01 00:00:00
abstract::Visual reaction time (RT) studies on patients with right hemisphere (RH) damage have demonstrated that the attentional imbalance to stimuli occupying left and right positions exists even within the "intact" ipsilesional hemifield. The purpose of the present study was to test whether such patients might also exhibit re...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1994-7204
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Increasing proportion of the elderly in the driving population raises the importance of assuring their safety. We explored the effects of three different types of cognitive training on the cognitive function, brain structure, and driving safety of the elderly. METHODS:Thirty-seven healthy elderly daily driv...
journal_title:Behavioural neurology
pub_type: 杂志文章,随机对照试验
doi:10.1155/2015/525901
更新日期:2015-01-01 00:00:00