Effects of a low-fat meal on the oral bioavailability of UFT and leucovorin in patients with colorectal cancer.

abstract：BACKGROUND:As cancer therapy can be harmful to spermatogenesis, men are generally advised to cryopreserve sperm before gonadotoxic treatment. Here, we compared fresh and frozen-thawed sperm quality in patients according to cancer type, and reported use rate in subsequent assisted reproductive technology (ART) cycles. ...

journal_title：International journal of clinical oncology

authors： Freour T,Mirallie S,Jean M,Barriere P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Zoledronic acid treatment reduces the incidence of skeletal-related events (SREs) in patients with bone metastases from breast, lung, and urologic cancers including prostate and renal cancer. The aim of this study was to evaluate the effect of zoledronic acid on SREs in patients with bone metastases from bla...

journal_title：International journal of clinical oncology

authors： Zaghloul MS,Boutrus R,El-Hossieny H,Kader YA,El-Attar I,Nazmy M

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Opioids are key drugs for cancer pain relief, but some patients, especially those who have gastroenterological cancers, suffer from severe opioid-induced bowel dysfunction (OBD), which reduces their quality of life. In order to achieve better pain relief, efforts to minimize OBD are required. METHODS:Betwee...

journal_title：International journal of clinical oncology

authors： Matsui T,Kojima T,Kojima H,Iwamoto N,Kure S,Uemura T,Fujimitsu Y,Sakamoto J

更新日期：2009-06-01 00:00:00

abstract：INTRODUCTION:We retrospectively evaluated the blood coagulation activity using the D-dimer level in the early period after gastrectomy and investigated whether postoperative hypercoagulation affects tumor recurrence and long-term survival in gastric cancer patients. METHODS:The study involved 650 patients who underwen...

journal_title：International journal of clinical oncology

authors： Hara K,Aoyama T,Hayashi T,Nakazono M,Nagasawa S,Shimoda Y,Kumazu Y,Numata M,Yamada T,Tamagawa H,Shiozawa M,Morinaga S,Yukawa N,Rino Y,Masuda M,Ogata T,Oshima T

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Cyclin E and p27 play pivotal roles in cancer development and progression. We investigated whether the prognosis in cases of non-small cell lung cancer without lymph node metastases that underwent complete resection could be associated with tissue expression of cyclin E, p27, and Ki-67. METHODS:Tumors from ...

journal_title：International journal of clinical oncology

authors： Takahashi S,Kamata Y,Tamo W,Koyanagi M,Hatanaka R,Yamada Y,Tsushima T,Takaya S,Fukuda I

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:This study searched for extra capsular tumour spread (ECS) as a prognostic factor for recurrence in terms of Disease Free Survival (DFS) and Overall Survival (OS). PATIENTS AND METHODS:For this study, from a retrospective database of the Doubs cancer registry, 823 eligible women with node positive breast ca...

journal_title：International journal of clinical oncology

authors： Dobi E,Bazan F,Dufresne A,Demarchi M,Villanueva C,Chaigneau L,Montcuquet P,Ivanaj A,Sautière JL,Maisonnette-Escot Y,Cals L,Algros MP,Woronoff AS,Pivot X

更新日期：2013-08-01 00:00:00

abstract：:Juvenile granulosa cell tumor (GCT) is a rare tumor, and the majority (90%) are reported in the prepubertal or under-30-year age group, in contrast to the adult type, which is more common in the fifth decade. On histopathological examination, juvenile GCTs are distinct from the adult type of GCT, and have a lower risk...

journal_title：International journal of clinical oncology

authors： Kaur H,Bagga R,Saha SC,Gainder S,Srinivasan R,Adhya AK,Dhaliwal LK

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Radium-223 is a first-in-class targeted alpha therapy to prolong overall survival (OS) in castration-resistant prostate cancer with bone metastases (mCRPC). The aim of the present analysis was to assess the long-term safety with radium-223 in Japanese patients with mCRPC. METHODS:Patients with symptomatic m...

journal_title：International journal of clinical oncology

authors： Uemura H,Uemura H,Nagamori S,Wakumoto Y,Kimura G,Kikukawa H,Yokomizo A,Mizokami A,Kosaka T,Masumori N,Kawasaki Y,Yonese J,Nasu Y,Fukasawa S,Sugiyama T,Kinuya S,Hosono M,Yamaguchi I,Akagawa T,Matsubara N

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The pasteurized autogenous bone graft (PABG) is a new method to reuse resected and diseased autogenous bones after heat treatment at a comparatively low temperature (60 degrees C-65 degrees C). METHODS:The subjects of this study were ten patients with musculoskeletal tumor who underwent surgery with a PABG ...

journal_title：International journal of clinical oncology

authors： Sakayama K,Kidani T,Fujibuchi T,Kamogawa J,Yamamoto H,Shibata T

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Worldwide studies on lung adenocarcinoma have demonstrated a genetic divergence of the epidermal growth factor receptor (EGFR) pathway according to ethnicity, such as higher frequency of activated EGFR mutations among East Asian patients. However, such information is still lacking in some developing countrie...

journal_title：International journal of clinical oncology

authors： Rahman S,Kondo N,Yoneda K,Takuwa T,Hashimoto M,Orui H,Okumura Y,Tanaka F,Kumamoto K,Mostafa MG,Chowdhury GM,Haque A,Hasegawa S

更新日期：2014-02-01 00:00:00

abstract：:Pseudoaneurysm complicating osteochondroma is extremely rare. We describe a pseudoaneurysm in the popliteal fossa of a 21-year-old man, occurring 5 years after apparently incomplete resection of an osteochondroma at that site. We found magnetic resonance imaging and magnetic resonance angiography to be of great diagno...

journal_title：International journal of clinical oncology

authors： Otsuka T,Yonezawa M,Kamiyama F,Matusita Y,Matui N

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Early tumor shrinkage (ETS) is a response-related endpoint of clinical trials of chemotherapy (CHT) of patients with metastatic colorectal cancer (mCRC). It identifies a dimensional reduction of tumor size by at least 20-30% after 6-8 weeks of CHT. METHODS:A literature search of randomized trials of systemi...

journal_title：International journal of clinical oncology

authors： Colloca GA,Venturino A,Guarneri D

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that somatic mutations in the AT-rich interactive domain 1A (SWI-like) gene (ARID1A) are the most common genetic changes in clear cell carcinoma of the ovary (CCC). A gene mutation of ARID1A was found in approximately half of CCC cases, and led to absence of the encoded protein and ...

journal_title：International journal of clinical oncology

authors： Itamochi H,Oumi N,Oishi T,Shoji T,Fujiwara H,Sugiyama T,Suzuki M,Kigawa J,Harada T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Although regorafenib or trifluridine/tipiracil (FTD/TPI) has been recognized as a later-line standard treatment in patients with metastatic colorectal cancer (mCRC), not all patients have beneficial outcomes. This study aimed to develop a prognostic scoring system for evaluating the overall survival (OS) ben...

journal_title：International journal of clinical oncology

authors： Moriwaki T,Fukuoka S,Masuishi T,Takashima A,Kumekawa Y,Kajiwara T,Yamazaki K,Esaki T,Makiyama A,Denda T,Hatachi Y,Suto T,Sugimoto N,Enomoto M,Ishikawa T,Kashiwada T,Oki E,Komatsu Y,Tsuji A,Tsuchihashi K,Sakai D,

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:The purpose of our study was to evaluate the efficacy of a new combination antiemetic therapy consisting of palonosetron, aprepitant, and dexamethasone in gastric cancer patients undergoing chemotherapy with S-1 plus cisplatin. METHODS:This prospective, multi-institutional observational study assessed patient-...

journal_title：International journal of clinical oncology

authors： Oyama K,Fushida S,Kaji M,Takeda T,Yabushita K,Nezuka H,Kinami S,Kadoya N,Takai Y,Tsukioka Y,Ohyama S,Tsuji K,Tsukada T,Kinoshita J,Fujimura T,Ohta T

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate whether serum alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) trends might be correlated with overall survival rates in patients with recurrent hepatocellular carcinoma (HCC) undergoing trans-catheter arterial chemo-embolization (TACE). METHODS:We pe...

journal_title：International journal of clinical oncology

authors： Arai T,Kobayashi A,Ohya A,Takahashi M,Yokoyama T,Shimizu A,Motoyama H,Furusawa N,Notake T,Kitagawa N,Sakai H,Imamura H,Kadoya M,Miyagawa S

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:High-risk factors for recurrence of head and neck squamous cell carcinoma after surgical resection include involvement of ≥ 2 regional lymph nodes, extracapsular spread, and microscopic involvement of resected mucosal margins. Adjuvant chemoradiotherapy is thought to improve postoperative locoregional contro...

journal_title：International journal of clinical oncology

authors： Yokota T,Onitsuka T,Kusafuka K,Ogawa H,Onozawa Y,Nakagawa M,Iida Y,Kamijo T,Nishimura T,Nakajima T,Boku N,Yasui H

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:There is no standard chemotherapy available for unresectable or metastatic small bowel adenocarcinoma (SBA) because of its rarity. This systematic review aims to assess the efficacy and safety of chemotherapy for patients with unresectable or metastatic SBA. METHODS:In accordance with the PRISMA statements,...

journal_title：International journal of clinical oncology

authors： Nishikawa Y,Hoshino N,Horimatsu T,Funakoshi T,Hida K,Sakai Y,Muto M,Nakayama T

更新日期：2020-08-01 00:00:00

abstract：:The updated 2016 World Health Organization (WHO) Classification of Tumours of the Central Nervous System (CNS) has incorporated molecular parameters into pathological diagnosis, for the first time in the molecular era. While it has led to the more precise diagnoses of well-understood entities and the better comprehens...

journal_title：International journal of clinical oncology

authors： Onizuka H,Masui K,Komori T

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Boron neutron capture therapy (BNCT) is among the radiation treatments known to have a selective lethal effect on tumor cells. This study summarizes the tumor responses and the acute and late adverse effects of BNCT in the treatment of patients with both recurrent and newly diagnosed T4 salivary gland carcinoma...

journal_title：International journal of clinical oncology

authors： Aihara T,Morita N,Kamitani N,Kumada H,Ono K,Hiratsuka J,Harada T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Although many studies have already shown that lymph node metastasis is one of the major prognostic factors for cervical cancer, the therapeutic significance of para-aortic lymphadenectomy for the surgical treatment of cervical cancer remains controversial. METHODS:A total of 308 patients diagnosed with stag...

journal_title：International journal of clinical oncology

authors： Tsuruga T,Fujimoto A,Kawana K,Mori M,Hasumi Y,Kino N,Tomio K,Miura S,Tanikawa M,Sone K,Miyamoto Y,Ikeda Y,Kojima S,Adachi K,Nagasaka K,Matsumoto Y,Arimoto T,Oda K,Nakagawa S,Horie K,Yasugi T,Yokota H,Osuga Y,

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:To avoid the loss of fertility, chemotherapy should be chosen as an adjuvant treatment after trachelectomy. Our study evaluated the effectiveness and safety of adjuvant chemotherapy after abdominal trachelectomy for cervical cancer. METHODS:Our institutional review board approved this clinical study, and in...

journal_title：International journal of clinical oncology

authors： Okugawa K,Yahata H,Sonoda K,Kodama K,Yagi H,Ohgami T,Yasunaga M,Onoyama I,Kaneki E,Asanoma K,Kobayashi H,Kato K

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Whether the administration of calcium (Ca) and magnesium (Mg) can reduce oxaliplatin-related neurotoxicity remains controversial. In addition, little is known about the effects of Ca/Mg on the blood level of platinum or objective tumor progression. PATIENTS AND METHODS:Patients receiving modified FOLFOX6 fo...

journal_title：International journal of clinical oncology

authors： Ishibashi K,Okada N,Miyazaki T,Sano M,Ishida H

更新日期：2010-02-01 00:00:00

abstract：:Among head and neck squamous cell carcinoma (HNSCC), the incidence of oropharyngeal SCC (OPSCC) is increasing in contrast to carcinoma with origin in other subsites. Human papillomavirus (HPV) is now recognized as a significant risk factor of the carcinogenesis of OPSCC. The HPV-related OPSCC patients tend to be relat...

journal_title：International journal of clinical oncology

authors： Okami K

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Immune responses in the uterine cervix are considered to play an important role in persistent human papillomavirus (HPV) infection and carcinogenesis, but many aspects of the mechanism are still unclear. The goal of this study was to measure cytokines to analyze immune responses in patients with cervical int...

journal_title：International journal of clinical oncology

authors： Iwata T,Fujii T,Morii K,Saito M,Sugiyama J,Nishio H,Morisada T,Tanaka K,Yaguchi T,Kawakami Y,Aoki D

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Enlarged pelvic nodes are commonly found during preoperative imaging studies in cervical cancer patients and may represent tumor metastasis. It remains controversial whether debulking of these enlarged nodes prior to definitive radiotherapy offers any survival benefit to the patient. METHODS:Enlarged suspic...

journal_title：International journal of clinical oncology

authors： Cheung TH,Lo KW,Yim SF,Yau SH,Yu MM,Yeung WK

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Despite increasing interest in minimally invasive surgery, prevalence data are completely absent. Our objective was to analyze clinico-epidemiological variations of surgery for renal malignancy in Japan with emphasis on annual trends and regional gaps, and to analyze factors affecting choice of open versus m...

journal_title：International journal of clinical oncology

authors： Sugihara T,Yasunaga H,Horiguchi H,Tsuru N,Fujimura T,Nishimatsu H,Kume H,Ohe K,Matsuda S,Fushimi K,Homma Y

更新日期：2013-12-01 00:00:00

abstract：:The two main malignant hepatic tumors in children are hepatoblastomas (HBLs) and hepatocellular carcinomas (HCCs). The past two decades have brought significant improvement to the outcomes of children diagnosed with malignant hepatic tumors, especially HBL, due to improvements in diagnosis and treatment. Histological ...

journal_title：International journal of clinical oncology

authors： Hiyama E

更新日期：2013-12-01 00:00:00

abstract：:A case of mantle cell lymphoma (MCL) associated with multiple lymphomatous polyposis (MLP) is reported is a 62-year-old woman, with special reference to the patient's clinical features and response to treatment. There were multiple widespread polypoid lesions in the entire gastrointestinal tract, with ileocecal masses...

journal_title：International journal of clinical oncology

authors： Tsujimura H,Takagi T,Tamaru J,Sakai C

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:The mechanisms underlying cognitive decline after radiotherapy not directed at brain areas remains unclear. We previously suggested that adjuvant breast radiotherapy in breast conservation therapy could lower memory function soon after therapy, and that the process might be partially mediated by plasma inter...

journal_title：International journal of clinical oncology

authors： Shibayama O,Yoshiuchi K,Inagaki M,Matsuoka Y,Yoshikawa E,Sugawara Y,Akechi T,Wada N,Imoto S,Murakami K,Ogawa A,Uchitomi Y

更新日期：2019-01-01 00:00:00