Chemotherapy for patients with unresectable or metastatic small bowel adenocarcinoma: a systematic review.

Abstract:

BACKGROUND:There is no standard chemotherapy available for unresectable or metastatic small bowel adenocarcinoma (SBA) because of its rarity. This systematic review aims to assess the efficacy and safety of chemotherapy for patients with unresectable or metastatic SBA. METHODS:In accordance with the PRISMA statements, literature search was conducted using PubMed, Scopus, and the Cochrane Central Register of Controlled Trials. The included studies were prospective randomized, nonrandomized, or observational studies. Risk of bias was assessed the ROBINS-I tool. RESULTS:Seven prospective single-arm Phase II studies were included in this review. Six of them were assessed as having a moderate risk of bias and one as having a serious risk of bias. A meta-analysis was not performed, because the studies were single-arm. Systemic chemotherapy based on fluoropyrimidine regimens achieved favorable outcomes with acceptable adverse effects as a first therapy; however, the regimens differed in each study. The object response rate was 18-50%, and the disease control rate was 29-87%. With 5-fluorouracil, adriamycin, and mitomycin-C regimen, one treatment-related death occurred. A second line of therapy including chemotherapy with nab-paclitaxel also showed favorable efficacy. The object response rate was 20%, and the disease control rate was 50%. CONCLUSIONS:Systemic chemotherapy based on fluoropyrimidine regimens was mainly used for unresectable or metastatic SBA. While it may achieve favorable outcomes with acceptable adverse effects, further evidence is needed.

journal_name

Int J Clin Oncol

authors

Nishikawa Y,Hoshino N,Horimatsu T,Funakoshi T,Hida K,Sakai Y,Muto M,Nakayama T

doi

10.1007/s10147-020-01703-z

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

1441-1449

issue

8

eissn

1341-9625

issn

1437-7772

pii

10.1007/s10147-020-01703-z

journal_volume

25

pub_type

杂志文章
  • Comparison between cancer specialists and general physicians regarding the education of nurse practitioners in Japan: a postal survey of the Japanese Society of Clinical Oncology.

    abstract:BACKGROUND:Japanese physicians' attitudes regarding the education of nurse practitioners (NPs) are not well described. PARTICIPANTS AND METHODS:A survey was mailed to 1,094 board members of the Japanese Society of Clinical Oncology (JSCO) and the Japanese Primary Care Association (JPCA), and the directors of the clini...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-012-0460-2

    authors: Ishida Y,Hatao M,Fukushima O,Mori M,Isozaki F,Okuyama A

    更新日期:2013-10-01 00:00:00

  • How asymptomatic are early cancer patients of five organs based on registry data in Japan.

    abstract:BACKGROUND:One reason for the low cancer screening rate in Japan is that people are not concerned about cancer if they do not have symptoms. METHODS:The authors retrospectively analyzed 18,405 cancer patients using hospital-based cancer registry data collected between 2007 and 2013 at the 13 hospitals of Shimane Prefe...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-018-1287-2

    authors: Nakabayashi N,Hirose M,Suzuki R,Suzumiya J,Igawa M

    更新日期:2018-10-01 00:00:00

  • Combined chemotherapy with carboplatin plus irinotecan showed favorable efficacy in a patient with relapsed small cell carcinoma of the prostate complicated with meningeal carcinomatosis.

    abstract::We report the case of a 65-year-old man with recurrent prostate cancer who presented with meningeal carcinomatosis. In September 2007, he had been diagnosed with mixed type small cell carcinoma and adenocarcinoma at clinical stage T4N1M1 (primary prostate tumor with multiple bone, liver, and lymph node metastases) and...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-008-0869-9

    authors: Yamada T,Ohtsubo K,Mouri H,Yamashita K,Yasumoto K,Izumi K,Zen Y,Watanabe H,Yano S

    更新日期:2009-10-01 00:00:00

  • Preoperative biliary drainage-related inflammation is associated with shorter survival in biliary tract cancer patients.

    abstract:BACKGROUND:An association between inflammation and patient prognosis has been reported in various types of cancer. The aim of this study was to evaluate the influence of preoperative biliary drainage-related inflammation in patients with biliary tract cancer. METHODS:The clinical data of 97 patients who underwent surg...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-016-0961-5

    authors: Kurahara H,Maemura K,Mataki Y,Sakoda M,Iino S,Kawasaki Y,Arigami T,Uenosono Y,Kijima Y,Shinchi H,Takao S,Natsugoe S

    更新日期:2016-10-01 00:00:00

  • A matched-pair comparison of intensity-modulated radiation therapy with cetuximab versus intensity-modulated radiation therapy with platinum-based chemotherapy for locally advanced head neck cancer.

    abstract:PURPOSE:We retrospectively compared the efficacy of intensity-modulated radiotherapy (IMRT) and cetuximab (IMRT/cetuximab) versus IMRT and platinum-based chemotherapy (IMRT/platinum) for locally advanced head neck squamous cell carcinoma (LAHNSCC). METHODS:Thirty-one IMRT/cetuximab patients were matched 1:2 with 62 IM...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0540-y

    authors: Huang J,Baschnagel AM,Chen P,Gustafson G,Jaiyesmi I,Folbe M,Ye H,Akervall J,Krauss D

    更新日期:2014-04-01 00:00:00

  • Aggressive angiomyxoma mimicking inguinal hernia in a man.

    abstract::We report the case of a 37-year-old Japanese man who presented with a left lower abdominal mass that was initially interpreted clinically as an inguinal hernia. The patient reported a swelling in his left lower abdomen over the past 6 months. Magnetic resonance imaging revealed a left inguinal mass extending from the ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-008-0850-7

    authors: Minagawa T,Matsushita K,Shimada R,Takayama H,Hiraga R,Uehara T,Murata Y

    更新日期:2009-08-01 00:00:00

  • Prognostic significance of thymidylate synthase in patients with metastatic colorectal cancer who receive protracted venous infusions of 5-fluorouracil.

    abstract:BACKGROUND:This study was conducted to evaluate the prognostic significance of thymidylate synthase (TS) expression in the tumor tissue of patients with metastatic colorectal cancer (CRC) who received protracted venous infusions of 5-fluorouracil (5-FU). METHODS:We retrospectively analyzed the prognostic value of TS e...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-004-0425-1

    authors: Hosokawa A,Yamada Y,Shimada Y,Muro K,Hamaguchi T,Morita H,Araake M,Orita H,Shirao K

    更新日期:2004-10-01 00:00:00

  • No significant impact of response to prior androgen receptor-axis-targeted agents on the efficacy of subsequent docetaxel in patients with metastatic castration-resistant prostate cancer.

    abstract:BACKGROUND:To investigate whether the response to an androgen receptor-axis-targeted (ARAT) agent is associated with the efficacy of subsequent docetaxel in metastatic castration-resistant prostate cancer (mCRPC) patients. METHODS:This study included 114 consecutive mCRPC patients, comprising 54 and 60 patients who pr...

    journal_title:International journal of clinical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10147-017-1230-y

    authors: Miyake H,Matsushita Y,Tamura K,Motoyama D,Ito T,Sugiyama T,Otsuka A

    更新日期:2018-06-01 00:00:00

  • Stereotactic body radiotherapy in patients with chronic obstructive pulmonary disease and interstitial pneumonia: a review.

    abstract::Stereotactic body radiation therapy (SBRT) can yield excellent local tumor control, as well as survival benefit comparable to that of surgery for early-stage lung cancer. However, in terms of toxicity, SBRT might lead to fatal radiation pneumonitis. Lung diseases, such as chronic obstructive pulmonary disease (COPD) a...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s10147-019-01432-y

    authors: Doi H,Nakamatsu K,Nishimura Y

    更新日期:2019-08-01 00:00:00

  • Low incidence of KIT gene mutations and no PDGFRA gene mutations in primary cutaneous melanoma: an immunohistochemical and molecular genetic study of Japanese cases.

    abstract:BACKGROUND:Although several studies have reported the incidence of KIT and PDGFRA gene mutations in cutaneous melanomas of Caucasians, only one report is available for Mongoloids, including Japanese. In Japan, melanoma is an uncommon neoplasm compared with countries with Caucasian populations. METHODS:In this study, p...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-010-0087-0

    authors: Terada T

    更新日期:2010-10-01 00:00:00

  • Clinical trials and future potential of targeted therapy for ovarian cancer.

    abstract::Ovarian cancer is the leading cause of death in women with gynecological cancer. Most patients are diagnosed at an advanced stage with a poor prognosis. Currently, surgical tumor debulking followed by chemotherapy based on platinum and taxane is the standard treatment for advanced disease. However, these patients rema...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s10147-012-0459-8

    authors: Itamochi H,Kigawa J

    更新日期:2012-10-01 00:00:00

  • A history of the cancer registration system in Japan.

    abstract::In Japan, the first actual survey of morbidity from cancer was conducted by Dr. Mitsuo Segi in Miyagi Prefecture from 1951 to 1953. Population-based cancer registries were started in 1957 in Hiroshima and 1958 in Nagasaki for the follow-up of survivors of the atomic bombings. Public population-based cancer registries,...

    journal_title:International journal of clinical oncology

    pub_type: 历史文章,杂志文章

    doi:10.1007/s10147-008-0759-1

    authors: Okamoto N

    更新日期:2008-04-01 00:00:00

  • Glycosylation in bladder cancer.

    abstract::Complex carbohydrates are major components of the cell membrane and they play crucial roles in cell-cell and cell-extracellular matrix interactions, as well as in signal transduction. They consist of three kinds of molecular species; glycoproteins, proteoglycans, and glycosphingolipids. There is a distinct difference ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s10147-008-0809-8

    authors: Ohyama C

    更新日期:2008-08-01 00:00:00

  • Immune-resistant mechanisms in cancer immunotherapy.

    abstract::Immune checkpoint inhibitors (ICI) such as PD-1/PD-L1 antibodies (Abs) and CTLA4 Abs and T cell-based adoptive cell therapies are effective for patients with various cancers. However, response rates of ICI monotherapies are still limited due to lack of immunogenic antigens and various immune-resistant mechanisms. The ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s10147-019-01611-x

    authors: Kawakami Y,Ohta S,Sayem MA,Tsukamoto N,Yaguchi T

    更新日期:2020-05-01 00:00:00

  • Adenoendocrine cell carcinoma of the gallbladder clinically mimicking squamous cell carcinoma.

    abstract::We present the case of a 62-year-old Japanese man whose histological diagnosis was adenoendocrine cell carcinoma of the gallbladder at autopsy, but whose antemortem diagnosis was squamous cell carcinoma. The patient was admitted to hospital with complaints of occasional vomiting and abdominal pain. Abdominal computed ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-008-0810-2

    authors: Taniguchi H,Sakagami J,Suzuki N,Hasegawa H,Shinoda M,Tosa M,Baba T,Yasuda H,Kataoka K,Yoshikawa T

    更新日期:2009-04-01 00:00:00

  • Gastrectomy for invasive micropapillary carcinoma is associated with poorer disease-free and disease-specific survival.

    abstract:BACKGROUND:Invasive micropapillary carcinoma (IMPC) is a relatively rare subtype of gastric adenocarcinoma and has aggressive histopathologic characteristics, including lymphatic and vascular invasion. However, the associated long-term survival outcomes remain unclear. This study aimed to compare the clinicopathologica...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-019-01514-x

    authors: Kano M,Hihara J,Kaneko M,Uemura K,Ohge H,Sueda T

    更新日期:2019-12-01 00:00:00

  • Gastrectomy and chemotherapy with S-1 for gastric cancer in a patient with acquired immunodeficiency syndrome.

    abstract::Total gastrectomy and chemotherapy with S-1 after surgery were performed in a 50-year-old woman with gastric cancer associated with acquired immunodeficiency syndrome (AIDS). She was given a diagnosis of gastric cancer at the lesser curvature of the body of the stomach, and distal gastrectomy was performed in December...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-010-0114-1

    authors: Suzuki R,Ariizumi S,Araida T,Hayashi K,Yamamoto M

    更新日期:2011-02-01 00:00:00

  • The safety and efficacy of cisplatin plus gemcitabine in recurrent ovarian cancer.

    abstract:BACKGROUND:The activity and synergy for the combination treatment of cisplatin and gemcitabine has been identified in a variety of human tumor cells, including ovarian cancer cells, and has been widely approved for the treatment of non-small cell lung cancer, pancreatic cancer and biliary tract cancer. As the gastroint...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0599-5

    authors: Tomita Y,Saito T,Okadome M,Eto T,Ariyoshi K,Shimamoto K

    更新日期:2014-08-01 00:00:00

  • Focal therapy with high-intensity focused ultrasound for the localized prostate cancer for Asian based on the localization with MRI-TRUS fusion image-guided transperineal biopsy and 12-cores transperineal systematic biopsy: prospective analysis of oncolog

    abstract:BACKGROUND:We evaluated clinical outcomes of region target focal therapy with high-intensity focused ultrasound (HIFU) for the localized prostate cancer (PCa) based on magnetic resonance imaging-based biopsy and systematic prostate biopsy for Asian. METHODS:We prospectively recruited patients with localized PCa, locat...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-020-01723-9

    authors: Shoji S,Hiraiwa S,Uemura K,Nitta M,Hasegawa M,Kawamura Y,Hashida K,Hasebe T,Tajiri T,Miyajima A

    更新日期:2020-10-01 00:00:00

  • Health-related quality of life in Japanese patients with metastatic renal cell carcinoma treated with sunitinib.

    abstract:BACKGROUND:To analyze the impact of sunitinib treatment on health-related quality of life (HRQOL) in Japanese patients with metastatic renal cell carcinoma (mRCC). METHODS:This study prospectively included 90 consecutive patients with mRCC treated with sunitinib for at least 3 months. HRQOL in these patients was asses...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-011-0364-6

    authors: Miyake H,Harada K,Kusuda Y,Fujisawa M

    更新日期:2013-04-01 00:00:00

  • Effect of postoperative radiotherapy on survival in duodenal adenocarcinoma: a propensity score-adjusted analysis of Surveillance, Epidemiology, and End Results database.

    abstract:PURPOSE:The use of adjuvant treatment has not been sufficiently investigated in duodenal adenocarcinoma. This study evaluated the effect of postoperative radiotherapy (PORT) on survival outcomes in this rare malignancy. METHODS:We identified patients who were diagnosed between 2004 and 2013 in the Surveillance, Epidem...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-017-1226-7

    authors: Lim YJ,Kim K

    更新日期:2018-06-01 00:00:00

  • Boron neutron capture therapy for advanced salivary gland carcinoma in head and neck.

    abstract:PURPOSE:Boron neutron capture therapy (BNCT) is among the radiation treatments known to have a selective lethal effect on tumor cells. This study summarizes the tumor responses and the acute and late adverse effects of BNCT in the treatment of patients with both recurrent and newly diagnosed T4 salivary gland carcinoma...

    journal_title:International journal of clinical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10147-013-0580-3

    authors: Aihara T,Morita N,Kamitani N,Kumada H,Ono K,Hiratsuka J,Harada T

    更新日期:2014-01-01 00:00:00

  • Effect of TU-100, a traditional Japanese medicine, administered after hepatic resection in patients with liver cancer: a multi-center, phase III trial (JFMC40-1001).

    abstract:BACKGROUND:This multi-center, phase III trial assesses the efficacy of daikenchuto (TU-100) on gastrointestinal disorders after hepatic resection (UMIN Registration No. 000003103). MATERIALS AND METHODS:A total of 231 patients, who underwent hepatic resection at 26 Japanese centers, were enrolled. Patients were random...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s10147-014-0678-2

    authors: Shimada M,Morine Y,Nagano H,Hatano E,Kaiho T,Miyazaki M,Kono T,Kamiyama T,Morita S,Sakamoto J,Kusano M,Saji S,Kanematsu T,Kitajima M

    更新日期:2015-02-01 00:00:00

  • Oncologic and obstetric outcomes and complications during pregnancy after fertility-sparing abdominal trachelectomy for cervical cancer: a retrospective review.

    abstract:BACKGROUND:Trachelectomy was developed as a fertility-sparing surgery for early-stage cervical cancer in patients of childbearing age. The purpose of this study is to evaluate oncologic and obstetric outcomes and complications after abdominal trachelectomy. METHODS:We began to perform abdominal trachelectomy in 2005. ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-016-1059-9

    authors: Okugawa K,Kobayashi H,Sonoda K,Kaneki E,Kawano Y,Hidaka N,Egashira K,Fujita Y,Yahata H,Kato K

    更新日期:2017-04-01 00:00:00

  • Sequential chemotherapy using gemcitabine + carboplatin followed by gemcitabine + carboplatin + docetaxel for advanced upper-tract urothelial cancer.

    abstract:BACKGROUND:Retrospective evaluation of the effectiveness and adverse events (AEs) of a sequential chemotherapy regimen using gemcitabine + carboplatin (GCarbo) followed by GCarbo + docetaxel (GCarboD) for advanced upper-tract urothelial carcinoma (UTUC). METHODS:We treated 56 patients with advanced UTUC. Mean patient ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-015-0846-z

    authors: Yoneyama T,Imai A,Hatakeyama S,Hashimoto Y,Koie T,Ohyama C

    更新日期:2015-12-01 00:00:00

  • The role of Aurora B expression in non-tumor liver tissues of patients with hepatocellular carcinoma.

    abstract:BACKGROUND:Aurora B is a serine-threonine kinase and chromosomal passenger protein involved in the control of chromosome assembly and segregation during mitosis. Aberrant expression of Aurora B has been reported in some tumors, including lung and hepatocellular carcinoma (HCC). We investigated the role of Aurora B expr...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0593-y

    authors: Tovuu LO,Utsunomiya T,Imura S,Morine Y,Ikemoto T,Arakawa Y,Mori H,Hanaoka J,Kanamoto M,Sugimoto K,Saito Y,Yamada S,Asanoma M,Shimada M

    更新日期:2014-08-01 00:00:00

  • Testicular metastasis from an extramedullary plasmacytoma.

    abstract::Plasmacytoma is a blood disease featuring the proliferation of abnormal plasmacytes accompanied by the production of monoclonal immunoglobulins. It usually arises in the medulla; thus, extramedullary plasmacytoma is rare, and metastatic testicular tumors are also infrequent. In this report, we present a case of testic...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-008-0769-z

    authors: Kamisawa H,Akita H,Naiki T,Kato T,Okamura T

    更新日期:2008-10-01 00:00:00

  • A survival analysis using physique-adjusted tumor size of non-small cell lung cancer.

    abstract:BACKGROUND:Differences in individual body sizes have not been well considered when analyzing the survival of patients with non-small cell lung cancer (NSCLC). We hypothesized that physique-adjusted tumor size is superior to actual tumor size in predicting the prognosis. METHODS:Eight hundred and forty-two patients who...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-017-1219-6

    authors: Ozeki N,Fukui T,Kawaguchi K,Nakamura S,Hakiri S,Kato T,Hirakawa A,Yokoi K

    更新日期:2018-04-01 00:00:00

  • Thinking twice before abandoning first-line chemotherapy in ovarian cancer: report of two cases and literature review. Passing from tri-weekly to weekly regimens.

    abstract::We present two cases of advanced ovarian cancer treated with neoadjuvant chemotherapy with standard tri-weekly carboplatin and paclitaxel. Therapy was converted to weekly regimens because of disease progression, resulting in disease response. Weekly regimens could overcome drug resistance and this strategy should be a...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-011-0300-9

    authors: Marchetti C,Bellati F,Musella A,Napoletano C,Perniola G,Di Donato V,Pignata S,Nuti M,Panici PB

    更新日期:2012-08-01 00:00:00

  • Induction TPF chemotherapy followed by CRT with fractionated administration of cisplatin in patients with unresectable locally advanced head and neck cancer.

    abstract:BACKGROUND:In treatment of locally advanced squamous cell carcinoma of the head and neck (SCCHN), the use of docetaxel, cisplatin, and 5-fluorouracil (TPF) followed by high-dose cisplatin chemoradiotherapy (CRT) carries concerns over toxicity. We evaluated the feasibility of TPF as induction chemotherapy (IC) to Japane...

    journal_title:International journal of clinical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10147-019-01418-w

    authors: Okano S,Enokida T,Onoe T,Ota Y,Motegi A,Zenda S,Akimoto T,Tahara M

    更新日期:2019-07-01 00:00:00