Abstract:
BACKGROUND:The pasteurized autogenous bone graft (PABG) is a new method to reuse resected and diseased autogenous bones after heat treatment at a comparatively low temperature (60 degrees C-65 degrees C). METHODS:The subjects of this study were ten patients with musculoskeletal tumor who underwent surgery with a PABG in the 6 years between 1995 and 2000. RESULTS:The pasteurized bone developed into bone union in all patients, except for the elderly patients who required repeat surgery. There were no infected patients. The PABG was performed by three different types of reconstruction, a segmental method, an intercalary method, and a combination method with an artificial joint as a spacer. No local recurrence of tumor the pasteurized bone was observed from in any patient. CONCLUSION:The PABG appears to be a comparatively easy, safe, inexpensive, and effective reconstruction method for musculoskeletal tumors. The pasteurized autogenous bone graft (PABG) is a new method to reuse resected and diseased autogenous bones after heat treatment at a comparatively low temperature (60 degrees C-65 degrees C).
journal_name
Int J Clin Oncoljournal_title
International journal of clinical oncologyauthors
Sakayama K,Kidani T,Fujibuchi T,Kamogawa J,Yamamoto H,Shibata Tdoi
10.1007/s10147-004-0391-7subject
Has Abstractpub_date
2004-06-01 00:00:00pages
167-73issue
3eissn
1341-9625issn
1437-7772journal_volume
9pub_type
杂志文章abstract:BACKGROUND:Indocyanine green (ICG), an agent for measuring liver function, becomes fluorescent under near-infrared (NIR) light after binding to serum proteins. Hepatocellular carcinoma (HCC) with a deposit of preoperatively administered ICG becomes clearly detectable under ICG fluorography; however, it remains unclear ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-011-0367-3
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Neoadjuvant cisplatin-based chemotherapy for patients with muscle-invasive bladder cancer (BC) has better survival benefit than radical cystectomy (RC) alone. However, optimal dosing schedule, including drug selection, number of cycles, and interval between chemotherapy and cystectomy, as well as acceptable ...
journal_title:International journal of clinical oncology
pub_type: 临床试验,杂志文章
doi:10.1007/s10147-012-0447-z
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:This study searched for extra capsular tumour spread (ECS) as a prognostic factor for recurrence in terms of Disease Free Survival (DFS) and Overall Survival (OS). PATIENTS AND METHODS:For this study, from a retrospective database of the Doubs cancer registry, 823 eligible women with node positive breast ca...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-012-0439-z
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Obstructive colorectal cancer (CRC) is an emergency situation with high morbidity and mortality, but long-term outcomes of stage II/III obstructive CRC remain unclear. The aim of this study was to evaluate prognostic factors, including colorectal obstruction. METHODS:Data were retrospectively reviewed from ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-018-1307-2
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The activity and synergy for the combination treatment of cisplatin and gemcitabine has been identified in a variety of human tumor cells, including ovarian cancer cells, and has been widely approved for the treatment of non-small cell lung cancer, pancreatic cancer and biliary tract cancer. As the gastroint...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-013-0599-5
更新日期:2014-08-01 00:00:00
abstract:BACKGROUNDS:The presence of ≥5 circulating tumor cells (CTCs) in 7.5 ml blood is a poor prognostic marker in metastatic breast cancer (MBC). However, the role of human epidermal growth factor receptor 2 (HER2) status in CTCs is not known. METHODS:We prospectively assessed the prognostic value of this parameter for pat...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-011-0260-0
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Although many studies have already shown that lymph node metastasis is one of the major prognostic factors for cervical cancer, the therapeutic significance of para-aortic lymphadenectomy for the surgical treatment of cervical cancer remains controversial. METHODS:A total of 308 patients diagnosed with stag...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-015-0907-3
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Despite increasing interest in minimally invasive surgery, prevalence data are completely absent. Our objective was to analyze clinico-epidemiological variations of surgery for renal malignancy in Japan with emphasis on annual trends and regional gaps, and to analyze factors affecting choice of open versus m...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-012-0500-y
更新日期:2013-12-01 00:00:00
abstract::Approximately 10% of all extra-pulmonary small cell carcinoma (EPSCC) arises in the prostate either as de novo mixed adenocarcinoma with small cell components or a pure small cell carcinoma. Extensive disease carries a median survival of about 10 months in retrospective studies. We present a case managed aggressively ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-011-0198-2
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:To investigate whether the response to an androgen receptor-axis-targeted (ARAT) agent is associated with the efficacy of subsequent docetaxel in metastatic castration-resistant prostate cancer (mCRPC) patients. METHODS:This study included 114 consecutive mCRPC patients, comprising 54 and 60 patients who pr...
journal_title:International journal of clinical oncology
pub_type: 临床试验,杂志文章
doi:10.1007/s10147-017-1230-y
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Impact of R1 (microscopically margin-positive) resection on survival of patients with hepatoblastoma (HB) remains debatable. This study aimed to compare the long-term outcomes of R0 (microscopically margin-negative) and R1 resection for HB in children after hepatectomy. METHODS:We retrospectively reviewed f...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
abstract::Ovarian clear cell carcinoma (OCCC) is a histological subtype of epithelial ovarian carcinoma prevalent in Asians. No clear therapeutic selection based on molecular profile has been implemented for this disease. Oncogenic PIK3CA mutation, which activates the PIK3CA/AKT/mTOR signaling pathway, is a promising druggable ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-020-01622-z
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:This study aims to investigate the prognostic value of the ratio of hemoglobin-RDW (HRR) at diagnosis, in terms of overall survival (OS) and progression-free survival in patients with advanced non-small cell lung cancer (NSCLC). METHODS:Patients with metastatic NCCLC who attended two separate medical oncolo...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-019-01417-x
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Increase of the Ca2+-activated chloride channel TMEM16A is contribute to tumorigenesis. However, the expression level of TMEM16A and its underlying molecular mechanism for TMEM16Apromotingliver carcinogenesis is remains unknown. METHODS:In the present study, the expression of TMEM16A in hepatocellular carci...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-020-01653-6
更新日期:2020-06-01 00:00:00
abstract::We report a rare case of advanced ovarian mucinous adenocarcinoma in a pregnant woman. A 28-year-old pregnant Japanese woman was diagnosed with an ovarian tumor 8 cm in diameter at a local hospital. She was sent to a private hospital at 25 weeks of gestation because of the growing ovarian tumor. Advanced ovarian carci...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-007-0655-0
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Our previous nonrandomized prospective study showed that template-based lymphadenectomy improved survival among patients with renal pelvic cancer but not among patients with ureteral cancer. However, regional node sites vary according to the tumor's location in relation to the ureter. Therefore, this retrosp...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-016-1024-7
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Soft-tissue tumors are often accompanied by abnormal temperature distribution detected during palpation. However, the assessment of temperature distribution is subjective, limiting its wide use in cancer screening. The aim of this study was to evaluate the clinical significance of the thermal detection of so...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-020-01658-1
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Testicular cancer is a rare type of cancer in males. Since the disease is seen in young men and long-term survival is ensured following a high treatment success rate, fertility in testicular cancer patients is much more important. Prior to commencement of cancer treatment, patients are given counselling with...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-019-01534-7
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:We aimed to determine the appropriateness of adding 18F-fluorodeoxyglucose (FDG)-positronemission tomography (PET) to computed tomography (CT) and other pre-existing diagnostic imaging modalities for detecting subclinical lymph node metastasis of esophageal cancer, by comparing images from these modalities w...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-009-0893-4
更新日期:2009-10-01 00:00:00
abstract::Despite major improvements in the treatment of early-stage breast cancer over the past 15 years, many controversies exist surrounding the optimal adjuvant therapies for these patients. Adjuvant chemotherapy has been demonstrated to reduce recurrence and improve mortality, but questions persist as to what is the optima...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-003-0338-4
更新日期:2003-08-01 00:00:00
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journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-012-0460-2
更新日期:2013-10-01 00:00:00
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journal_title:International journal of clinical oncology
pub_type: 临床试验,杂志文章
doi:10.1007/s10147-004-0433-1
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:One reason for the low cancer screening rate in Japan is that people are not concerned about cancer if they do not have symptoms. METHODS:The authors retrospectively analyzed 18,405 cancer patients using hospital-based cancer registry data collected between 2007 and 2013 at the 13 hospitals of Shimane Prefe...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-018-1287-2
更新日期:2018-10-01 00:00:00
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journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-006-0601-6
更新日期:2006-12-01 00:00:00
abstract::In Japan, the first actual survey of morbidity from cancer was conducted by Dr. Mitsuo Segi in Miyagi Prefecture from 1951 to 1953. Population-based cancer registries were started in 1957 in Hiroshima and 1958 in Nagasaki for the follow-up of survivors of the atomic bombings. Public population-based cancer registries,...
journal_title:International journal of clinical oncology
pub_type: 历史文章,杂志文章
doi:10.1007/s10147-008-0759-1
更新日期:2008-04-01 00:00:00
abstract::Standard definitive radiotherapy for cervical cancer consists of whole pelvic external beam radiotherapy (EBRT) and intracavitary brachytherapy (ICBT). In Japan, high-dose-rate ICBT (HDR-ICBT) has been utilized in clinical practice for more than 40 years. Several randomized clinical trials demonstrated that HDR-ICBT a...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-008-0865-0
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Constipation is a common side effect of opioid therapy. An observational study of opioid-induced constipation (OIC) in Japanese patients with cancer (OIC-J) included 212 patients with various tumor types. This post hoc analysis of OIC-J evaluated a subgroup of patients with gastrointestinal (GI) cancer. MET...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-020-01790-y
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:SmithKline Beecham synthesized camptothecin analogs and identified nogitecan hydrochloride (topotecan) with a broad spectrum of antitumor activity and less toxicity than camptothecin. Because preclinical and overseas clinical data indicated the antitumor effect of nogitecan hydrochloride with a 5-day repeat-...
journal_title:International journal of clinical oncology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s101470200026
更新日期:2002-06-01 00:00:00
abstract::Brachytherapy is an important radio-therapeutic modality for a variety of malignancies, including prostate cancer, cervix cancer, breast cancer, vagina cancer, endometrium cancer, head and neck cancer, and many more. This technique has been shown to be an effective and safe non-pharmaceutical treatment with fewer seri...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-017-1155-5
更新日期:2017-08-01 00:00:00
abstract::We present the case of a 62-year-old Japanese man whose histological diagnosis was adenoendocrine cell carcinoma of the gallbladder at autopsy, but whose antemortem diagnosis was squamous cell carcinoma. The patient was admitted to hospital with complaints of occasional vomiting and abdominal pain. Abdominal computed ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-008-0810-2
更新日期:2009-04-01 00:00:00