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Multiple lymphomatous polyposis overexpressing cyclin D1.

Abstract：

:A case of mantle cell lymphoma (MCL) associated with multiple lymphomatous polyposis (MLP) is reported is a 62-year-old woman, with special reference to the patient's clinical features and response to treatment. There were multiple widespread polypoid lesions in the entire gastrointestinal tract, with ileocecal masses. Ileocecal resection was performed on immunohistochemical examination, the neoplastic cells in the polypoid lesions stained positively for cyclin D1. Two conventional anthracycline-containing regimens (adriamycin-cyclophosphamide-vincristine-prednisolone [CHOP] and mitantroxone-etoposide-vindesine-prednisolone [MEVP]) were administered, but had limited success. The patient has since been receiving an irinotecan-adriamycin regimen (irinotecan, 25 mg/m(2), days 1 and 2; adriamycin, 40 mg/m(2), day 3, once a month) as an outpatient and has achieved good partial remission. She is well with disease 48 months after the initiation of the initial treatment.

journal_name

Int J Clin Oncol

journal_title

International journal of clinical oncology

authors

Tsujimura H,Takagi T,Tamaru J,Sakai C

doi

10.1007/s101470050012

subject

Has Abstract

pub_date

2000-02-01 00:00:00

pages

62-4

issue

1

eissn

1341-9625

issn

1437-7772

journal_volume

5

pub_type

杂志文章

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