Recent progress and perspectives on prostate cancer biomarkers.

abstract：BACKGROUND:The combination of a new oral dihydropyrimidine dehydrogenase-inhibitory fluoropyrimidine (S-1) and cisplatin (CDDP) is one of the most active chemotherapy regimens for gastric cancer. However, the optimum schedule for this combination has not yet been determined. This study was conducted to establish the ma...

journal_title：International journal of clinical oncology

authors： Sato Y,Kondo H,Honda K,Takahari D,Sumiyoshi T,Tsuji Y,Yoshizaki N,Niitsu Y

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:We evaluated the relationship between biological behavior and microsatellite instability (MSI) status, with or without p53 status, in sporadic colorectal carcinoma. METHODS:MSI was analyzed with regard to biological features such as cellular proliferation and apoptotic cell death, in addition to clinicopath...

journal_title：International journal of clinical oncology

authors： Mori S,Ogata Y,Shirouzu K

更新日期：2004-08-01 00:00:00

abstract：:Specific allelic losses in the DNA of tumor cells are potential indicators of postoperative prognosis. Patients whose tumors showed allelic losses at 1p34, 3p25, 8p22, 13q12, 17p13.3, or 17q21.1 had a significantly higher risk of postoperative mortality than women whose tumors retained both alleles at those loci (the ...

journal_title：International journal of clinical oncology

authors： Hirano A,Utada Y,Haga S,Kajiwara T,Sakamoto G,Kasumi F,Nakamura Y,Emi M

更新日期：2001-02-01 00:00:00

abstract：:This review describes the pathological classification of pediatric liver cancer types and subtypes proposed at the recent international symposium (March 2011, Los Angeles, USA) and meetings involving pathologists serving as central reviewers for the Children's Oncology Group, Société Internationale d'Oncologie Pédiatr...

journal_title：International journal of clinical oncology

authors： Tanaka Y,Inoue T,Horie H

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Uterine carcinosarcomas (UCSs) are rare and aggressive tumors. The prognostic factors are not sufficiently known. METHODS:We performed a multi-institutional, retrospective study of women with stage I-IV UCS, diagnosed between 2007 and 2012. Data obtained from medical records included demographic, clinicopat...

journal_title：International journal of clinical oncology

authors： Harano K,Hirakawa A,Yunokawa M,Nakamura T,Satoh T,Nishikawa T,Aoki D,Ito K,Ito K,Nakanishi T,Susumu N,Takehara K,Watanabe Y,Watari H,Saito T

更新日期：2016-02-01 00:00:00

abstract：:A diagnosis of cervical cancer during pregnancy poses difficult management and ethical problems. Survival of the patient is the foremost concern, but fetal viability and well-being must also be addressed. Radical trachelectomy (RT) has recently begun to be performed as a possible treatment modality for early stage inv...

journal_title：International journal of clinical oncology

authors： Iwami N,Ishioka S,Endo T,Baba T,Nagasawa K,Takahashi M,Sugio A,Takada S,Mariya T,Mizunuma M,Saito T

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Obstructive colorectal cancer (CRC) is an emergency situation with high morbidity and mortality, but long-term outcomes of stage II/III obstructive CRC remain unclear. The aim of this study was to evaluate prognostic factors, including colorectal obstruction. METHODS:Data were retrospectively reviewed from ...

journal_title：International journal of clinical oncology

authors： Okuda Y,Shimura T,Yamada T,Hirata Y,Yamaguchi R,Sakamoto E,Kataoka H

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:We evaluated the association between subclinical interstitial lung disease (ILD) and fatal radiation pneumonitis (RP) in patients with thoracic tumors treated with thoracic radiotherapy (RT). METHODS:Sixty-two consecutive patients with thoracic tumors treated with thoracic RT were retrospectively analyzed. ...

journal_title：International journal of clinical oncology

authors： Yamaguchi S,Ohguri T,Matsuki Y,Yahara K,Oki H,Imada H,Narisada H,Korogi Y

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:This study searched for extra capsular tumour spread (ECS) as a prognostic factor for recurrence in terms of Disease Free Survival (DFS) and Overall Survival (OS). PATIENTS AND METHODS:For this study, from a retrospective database of the Doubs cancer registry, 823 eligible women with node positive breast ca...

journal_title：International journal of clinical oncology

authors： Dobi E,Bazan F,Dufresne A,Demarchi M,Villanueva C,Chaigneau L,Montcuquet P,Ivanaj A,Sautière JL,Maisonnette-Escot Y,Cals L,Algros MP,Woronoff AS,Pivot X

更新日期：2013-08-01 00:00:00

abstract：:Bile duct hamartomas, also known as von Meyenburg complexes, are benign neoplasms consisting of cystic dilatation of the bile duct surrounded by fibrous stroma. We report a rare case in a 60-year-old man who presented with coexistent von Meyenburg complex and esophageal carcinoma. Preoperative computed tomography did ...

journal_title：International journal of clinical oncology

authors： Mimatsu K,Oida T,Kawasaki A,Aramaki O,Kuboi Y,Katsura Y,Amano S

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Cyclin E and p27 play pivotal roles in cancer development and progression. We investigated whether the prognosis in cases of non-small cell lung cancer without lymph node metastases that underwent complete resection could be associated with tissue expression of cyclin E, p27, and Ki-67. METHODS:Tumors from ...

journal_title：International journal of clinical oncology

authors： Takahashi S,Kamata Y,Tamo W,Koyanagi M,Hatanaka R,Yamada Y,Tsushima T,Takaya S,Fukuda I

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Neuroendocrine carcinoma (NEC) of the esophagus and the stomach is aggressive. The purpose of this study was to determine the optimal therapeutic strategy. METHODS:Both clinicopathological factors and treatment results were examined in 34 patients with immunohistochemically diagnosed NEC of the upper gastro...

journal_title：International journal of clinical oncology

authors： Morita M,Taguchi K,Kagawa M,Nakanoko T,Uehara H,Sugiyama M,Ota M,Ikebe M,Sugimachi K,Esaki T,Toh Y

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Differences in individual body sizes have not been well considered when analyzing the survival of patients with non-small cell lung cancer (NSCLC). We hypothesized that physique-adjusted tumor size is superior to actual tumor size in predicting the prognosis. METHODS:Eight hundred and forty-two patients who...

journal_title：International journal of clinical oncology

authors： Ozeki N,Fukui T,Kawaguchi K,Nakamura S,Hakiri S,Kato T,Hirakawa A,Yokoi K

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Detailed information is not currently available on the incidence, natural course, and management of asymptomatic abnormal prostate findings incidentally detected by radiologic evaluations after BCG therapy for non-muscle-invasive bladder cancer patients. METHODS:We identified 38 patients who were evaluated ...

journal_title：International journal of clinical oncology

authors： Matsushima M,Kikuchi E,Akita H,Miyajima A,Oya M,Jinzaki M

更新日期：2017-06-01 00:00:00

abstract：:We report a rare case of advanced ovarian mucinous adenocarcinoma in a pregnant woman. A 28-year-old pregnant Japanese woman was diagnosed with an ovarian tumor 8 cm in diameter at a local hospital. She was sent to a private hospital at 25 weeks of gestation because of the growing ovarian tumor. Advanced ovarian carci...

journal_title：International journal of clinical oncology

authors： Ishioka S,Hayashi T,Endo T,Baba T,Honma H,Saito T

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Evaluation of the prognosis in patients with spinal metastases is important in decision making regarding surgical treatment. The purpose of this study was to investigate overall survival in patients with spinal metastases from lung cancer by histological subtype, and to investigate prognostic factors in pati...

journal_title：International journal of clinical oncology

authors： Dohzono S,Sasaoka R,Takamatsu K,Nakamura H

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:Boron neutron capture therapy (BNCT) is among the radiation treatments known to have a selective lethal effect on tumor cells. This study summarizes the tumor responses and the acute and late adverse effects of BNCT in the treatment of patients with both recurrent and newly diagnosed T4 salivary gland carcinoma...

journal_title：International journal of clinical oncology

authors： Aihara T,Morita N,Kamitani N,Kumada H,Ono K,Hiratsuka J,Harada T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The efficacy of individual chemotherapy based on chemosensitivity has scarcely been studied. METHODS:We examined the chemosensitivites for four anticancer agents - 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3 (2-chloroethyl)-3-nitrosourea hydrochloride (ACNU), carboplatin, cisplatin, and etoposide - of 43 ma...

journal_title：International journal of clinical oncology

authors： Ono A,Kanno H,Hayashi A,Nishimura S,Kyuma Y,Sato H,Ito S,Shimizu N,Chang CC,Gondo G,Yamamoto I,Sasaki T,Tanaka M

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Microvascular invasion (mvi) is an important risk factor for recurrent hepatocellular carcinoma (HCC), even after curative liver resection or orthotopic liver transplantation. However, mvi is difficult to detect preoperatively. The aim of this study was to clarify the risk factors of postoperative recurrence...

journal_title：International journal of clinical oncology

authors： Imura S,Teraoku H,Yoshikawa M,Ishikawa D,Yamada S,Saito Y,Iwahashi S,Ikemoto T,Morine Y,Shimada M

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:To avoid the loss of fertility, chemotherapy should be chosen as an adjuvant treatment after trachelectomy. Our study evaluated the effectiveness and safety of adjuvant chemotherapy after abdominal trachelectomy for cervical cancer. METHODS:Our institutional review board approved this clinical study, and in...

journal_title：International journal of clinical oncology

authors： Okugawa K,Yahata H,Sonoda K,Kodama K,Yagi H,Ohgami T,Yasunaga M,Onoyama I,Kaneki E,Asanoma K,Kobayashi H,Kato K

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The optimal treatment for elderly patients with glioblastoma has not been established. METHODS:We retrospectively analyzed the safety and efficacy of hypofractionated radiotherapy (45 Gy/15 fr) combined with temozolomide (TMZ) followed by bevacizumab (BEV) salvage treatment in 18 glioblastoma patients aged ...

journal_title：International journal of clinical oncology

authors： Matsuda KI,Sakurada K,Nemoto K,Kayama T,Sonoda Y

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Some childhood cancer survivors experience employment difficulties. This study aimed to describe pediatric brain-tumor survivors' employment status. METHODS:A cross-sectional, observational study was conducted, with questionnaires distributed to 101 pediatric brain-tumor survivors (aged 15 years or older) a...

journal_title：International journal of clinical oncology

authors： Sato I,Higuchi A,Yanagisawa T,Murayama S,Kumabe T,Sugiyama K,Mukasa A,Saito N,Sawamura Y,Terasaki M,Shibui S,Takahashi J,Nishikawa R,Ishida Y,Kamibeppu K

更新日期：2018-10-01 00:00:00

abstract：:In Japan, the National Cancer Center and university hospitals have initiated next-generation sequencing-based in vitro diagnostic testing for cancer patients as a method of clinical sequencing. Based on the molecular alterations detected, physicians can provide approved targeted therapy and access to investigational d...

journal_title：International journal of clinical oncology

authors： Takeuchi S,Okuda S

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the prognostic veracity for disease-specific survival (DSS) of the eighth edition of the American Joint Committee on Cancer/Union for International Cancer Control tumor-node-metastasis staging system (TNM-8) compared with the seventh edition (TNM-7) in a Chinese populati...

journal_title：International journal of clinical oncology

authors： Zhi J,Wu Y,Hu L,Zhao J,Liu H,Ruan X,Hou X,Zhang J,Zheng X,Gao M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinoma (IHCC) has a poor prognosis, and surgery remains the only effective treatment. However, tumor recurrence after primary hepatectomy is common. We examined the significance of repeat surgery for IHCC. METHODS:We collected data for all patients with IHCC between 1992 and 2018 (n...

journal_title：International journal of clinical oncology

authors： Tokuda K,Morine Y,Saito Y,Yamada S,Miyazaki K,Yamashita S,Okikawa S,Ikemoto T,Imura S,Shimada M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Irinotecan (CPT-11) and bolus 5-fluorouracil (5-FU)/leucovorin (LV) administered weekly for 4 weeks every 42 days (Saltz regimen) is active but substantially toxic in patients with metastatic colorectal cancer (CRC). The efficacy and toxicity of this regimen, however, have not been determined in Japanese pat...

journal_title：International journal of clinical oncology

authors： Fujishima H,Kikuchi I,Miyanaga O,Ueda A,Baba E,Mitsugi K,Harada M,Nakano S

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:To characterize clinical advantages in robot-assisted partial nephrectomy (RAPN) for targeting renal hilar tumors, and compare them with those of open PN (OPN). METHODS:This study included 31 consecutive patients with renal hilar tumors, consisting of 15 and 16 who received OPN and RAPN, respectively, betwe...

journal_title：International journal of clinical oncology

authors： Miyake H,Hinata N,Imai S,Furukawa J,Tanaka K,Fujisawa M

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:The activity and synergy for the combination treatment of cisplatin and gemcitabine has been identified in a variety of human tumor cells, including ovarian cancer cells, and has been widely approved for the treatment of non-small cell lung cancer, pancreatic cancer and biliary tract cancer. As the gastroint...

journal_title：International journal of clinical oncology

authors： Tomita Y,Saito T,Okadome M,Eto T,Ariyoshi K,Shimamoto K

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:We have performed 26 vaginal radical trachelectomies (RTs) for patients with early invasive uterine cervical cancer since 2003 and, to date, have experienced 8 deliveries. The procedure has a high risk for preterm labor and the subsequent occurrence of preterm premature rupture of membranes (pPROM). We repor...

journal_title：International journal of clinical oncology

authors： Takada S,Ishioka S,Endo T,Baba T,Morishita M,Akashi Y,Mizuuchi M,Adachi H,Kim M,Saito T

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Our previous nonrandomized prospective study showed that template-based lymphadenectomy improved survival among patients with renal pelvic cancer but not among patients with ureteral cancer. However, regional node sites vary according to the tumor's location in relation to the ureter. Therefore, this retrosp...

journal_title：International journal of clinical oncology

authors： Kondo T,Hara I,Takagi T,Kodama Y,Hashimoto Y,Kobayashi H,Iizuka J,Omae K,Yoshida K,Tanabe K

更新日期：2017-02-01 00:00:00