The pretreatment neutrophil-to-lymphocyte ratio predicts therapeutic response to radiation therapy and concurrent chemoradiation therapy in uterine cervical cancer.

abstract：BACKGROUND:We conducted a phase I dose escalation study to determine the maximum tolerated dose (MTD), the recommended dose (RD) and the safety profile of amrubicin (AMR) plus paclitaxel (PTX) combination regimen for patients with previously treated non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:PTX was admi...

journal_title：International journal of clinical oncology

authors： Kaira K,Sunaga N,Imai H,Kamide Y,Koga Y,Ono A,Kuwako T,Masuda T,Hisada T,Ishizuka T,Yamada M

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Although subcutaneous implantable ports have been indicated as venous access for chemotherapy, these devices have not been used routinely for hematological tumors. METHODS:Between May 2006 and April 2009, 39 ports were implanted in 37 patients with hematological tumors and 16 ports were implanted in 14 pati...

journal_title：International journal of clinical oncology

authors： Ohno H,Mizumoto C,Otsuki Y,Oguma S,Yoshida Y

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:This study was conducted to determine the efficacy and safety of low-dose chemotherapy with methotrexate (MTX) and vinblastine (VBL) for patients with desmoid tumors refractory to meloxicam treatment, focusing in particular on the relationship between the efficacy of this chemotherapy and catenin β-1 (CTNNB1...

journal_title：International journal of clinical oncology

authors： Nishida Y,Tsukushi S,Urakawa H,Hamada S,Kozawa E,Ikuta K,Ando Y,Ishiguro N

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Total pharyngolaryngectomy (TPL) is a conventional and standard surgical method for locoregional control of advanced hypopharyngeal cancer (HPC). This study aimed to define the clinicopathological prognostic factors of TPL by evaluating our surgical experience of TPL in the treatment of HPCs. METHODS:We ret...

journal_title：International journal of clinical oncology

authors： Omura G,Ando M,Saito Y,Kobayashi K,Yamasoba T,Asakage T

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:The purpose of our study was to evaluate the efficacy of a new combination antiemetic therapy consisting of palonosetron, aprepitant, and dexamethasone in gastric cancer patients undergoing chemotherapy with S-1 plus cisplatin. METHODS:This prospective, multi-institutional observational study assessed patient-...

journal_title：International journal of clinical oncology

authors： Oyama K,Fushida S,Kaji M,Takeda T,Yabushita K,Nezuka H,Kinami S,Kadoya N,Takai Y,Tsukioka Y,Ohyama S,Tsuji K,Tsukada T,Kinoshita J,Fujimura T,Ohta T

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:To investigate the prognostic and therapeutic implications of time to biochemical relapse (BCR) in patients with prostate cancer after radical prostatectomy. METHODS:The records of 3210 consecutive men with prostate cancer who underwent radical prostatectomy between January 1998 and June 2013 were retrospec...

journal_title：International journal of clinical oncology

authors： Pak S,You D,Jeong IG,Kim YS,Hong JH,Kim CS,Ahn H

更新日期：2019-10-01 00:00:00

abstract：:We report four patients with pancreatic metastasis of renal cell carcinoma who were successfully treated with radiation therapy. The patients were one woman and three men with a median age of 55 years (range, 49 to 62 years) who underwent radical nephrectomy for primary renal cell carcinoma. The median interval from n...

journal_title：International journal of clinical oncology

authors： Saito J,Yamanaka K,Sato M,Mori N,Sekii K,Yoshioka T,Itatani H,Nakatsuka S

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Uterine carcinosarcomas (UCSs) are rare and aggressive tumors. The prognostic factors are not sufficiently known. METHODS:We performed a multi-institutional, retrospective study of women with stage I-IV UCS, diagnosed between 2007 and 2012. Data obtained from medical records included demographic, clinicopat...

journal_title：International journal of clinical oncology

authors： Harano K,Hirakawa A,Yunokawa M,Nakamura T,Satoh T,Nishikawa T,Aoki D,Ito K,Ito K,Nakanishi T,Susumu N,Takehara K,Watanabe Y,Watari H,Saito T

更新日期：2016-02-01 00:00:00

abstract：:A 74-year-old female was referred to our hospital for non-muscle invasive bladder tumors initially treated at another hospital. Preoperatively, computed tomography and magnetic resonance imaging demonstrated non-muscle invasive bladder tumors and a vaginal tumor. A second transurethral resection of the bladder tumors,...

journal_title：International journal of clinical oncology

authors： Kaneko G,Kikuchi E,Hasegawa M,Miyajima A,Nakagawa K,Kameyama K,Oya M

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Syndecan-1 (SDC1) is reported to modulate several key processes of tumorigenesis and to show variable expression in many cancers. The cause of these variations in expression is not known to date. In this study, we compared SDC1 status with clinicopathologic parameters to evaluate the prognostic implications ...

journal_title：International journal of clinical oncology

authors： Lee SH,Choi EJ,Kim MS,Park JW,Lee YS,Kim SY,Kang CS

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:It is expected that cell-free and concentrated ascites reinfusion therapy (CART) will relieve the symptoms caused by ascites. To date, however, no report of objective changes in patients' symptoms has been published. We have therefore evaluated symptom management by CART. METHODS:From April 2011 to July 201...

journal_title：International journal of clinical oncology

authors： Ito T,Hanafusa N,Iwase S,Noiri E,Nangaku M,Nakagawa K,Miyagawa K

更新日期：2015-06-01 00:00:00

abstract：:We report four patients with hepatocellular carcinoma (all men, with liver cirrhosis and hepatitis C virus infections) who showed spontaneous regression of the tumor. When the spontaneous regression occurred all of the patients were over age 67 years. They showed a rapid increase of serum alpha-fetoprotein levels just...

journal_title：International journal of clinical oncology

authors： Kondo S,Okusaka T,Ueno H,Ikeda M,Morizane C

更新日期：2006-10-01 00:00:00

abstract：:Recent advances in molecular biology have identified the responsible genes for many hereditary cancer syndromes (familial tumors). Therefore, now, the final diagnosis of familial tumors can be done by molecular methods to detect the genetic alteration in the disease-causing responsible gene(s) in the patient. So-calle...

journal_title：International journal of clinical oncology

authors： Tomita N,Oto M

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Hormone receptor status has been one of the most important factors in predicting the response to endocrine therapy in breast cancer patients. However, half of those patients with estrogen receptor-positive tumors do not respond to endocrine therapy. There have been no universal factors for predicting resista...

journal_title：International journal of clinical oncology

authors： Kai K,Nishimura R,Arima N,Miyayama H,Iwase H

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Most Brenner tumors are benign, with only 1% being malignant. In this study we report on 13 cases with malignant Brenner tumor of the ovary and discuss the clinical, demographic and histologic features. METHOD:Thirteen patients with malignant Brenner tumor of the ovary who were treated at Selçuk University G...

journal_title：International journal of clinical oncology

authors： Gezginç K,Karatayli R,Yazici F,Acar A,Çelik Ç,Çapar M,Tavli L

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:As cancer therapy can be harmful to spermatogenesis, men are generally advised to cryopreserve sperm before gonadotoxic treatment. Here, we compared fresh and frozen-thawed sperm quality in patients according to cancer type, and reported use rate in subsequent assisted reproductive technology (ART) cycles. ...

journal_title：International journal of clinical oncology

authors： Freour T,Mirallie S,Jean M,Barriere P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:We aimed to find the prognostic factors predicting overall survival (OS) in patients with castration-resistant prostate cancer (CRPC) who had docetaxel (DTX) chemotherapy, and to construct a model predicting the optimum number of cycles of DTX. METHODS:A total of 279 CRPC patients who received DTX (≥50 mg/m...

journal_title：International journal of clinical oncology

authors： Matsuyama H,Shimabukuro T,Hara I,Kohjimoto Y,Suzuki K,Koike H,Uemura H,Hayashi T,Ueno M,Kodaira K,Tomita Y,Sakurai T,Shimizu N

更新日期：2014-10-01 00:00:00

abstract：:Collecting duct carcinoma (CDC) of the kidney is a rare and aggressive malignant tumor arising from the distal collecting tubules which has been shown to have a poor response to several kinds of systemic therapy. We present a case of metastatic CDC that responded favorably to a multiple tyrosine kinase inhibitor, suni...

journal_title：International journal of clinical oncology

authors： Miyake H,Haraguchi T,Takenaka A,Fujisawa M

更新日期：2011-04-01 00:00:00

abstract：:Research misconduct and fraud in clinical research is an increasing problem facing the scientific community. This problem is expected to increase due to discoveries in central statistical monitoring and with the increase in first-time clinical trial investigators in the increasingly global reach of oncology clinical t...

journal_title：International journal of clinical oncology

authors： Herson J

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Differences in individual body sizes have not been well considered when analyzing the survival of patients with non-small cell lung cancer (NSCLC). We hypothesized that physique-adjusted tumor size is superior to actual tumor size in predicting the prognosis. METHODS:Eight hundred and forty-two patients who...

journal_title：International journal of clinical oncology

authors： Ozeki N,Fukui T,Kawaguchi K,Nakamura S,Hakiri S,Kato T,Hirakawa A,Yokoi K

更新日期：2018-04-01 00:00:00

abstract：:Immune checkpoint inhibitors (ICIs)-such as antibodies to programmed cell death-1 (PD-1), to its ligand PD-L1, or to cytotoxic T lymphocyte-associated protein-4 (CTLA-4)-are an evolving treatment option for several types of cancer, but only a limited number of patients benefit from such therapy. Preclinical studies ha...

journal_title：International journal of clinical oncology

authors： Hayashi H,Nakagawa K

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Previous reports concerning the prevalence of human papillomavirus (HPV) in oral squamous cell carcinoma (OSCC) have observed varied results. The aim of this study was to evaluate the prevalence of HPV in oral premalignant lesions (OPL) and OSCC. For accurate HPV detection in oral lesions, comparative analys...

journal_title：International journal of clinical oncology

authors： Ishibashi M,Kishino M,Sato S,Morii E,Ogawa Y,Aozasa K,Kogo M,Toyosawa S

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:We aimed to determine the frequency of fibromyalgia syndrome (FM) in operated breast cancer patients and to research the relationship between FM and the severity of fatigue and quality of life in these breast cancer patients. METHODS:The demographic data of 101 operated breast cancer patients were recorded....

journal_title：International journal of clinical oncology

authors： Akkaya N,Atalay NS,Selcuk ST,Alkan H,Catalbas N,Sahin F

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:It is often difficult to diagnose large cell neuroendocrine carcinomas (LCNEC) of the lung using small biopsy specimens. Some recent studies attempted to diagnose LCNEC using biopsy specimens; in 2011, the International Association for the Study of Lung Cancer pathological panels suggested possible LCNEC as ...

journal_title：International journal of clinical oncology

authors： Tokito T,Kenmotsu H,Watanabe R,Ito I,Shukuya T,Ono A,Nakamura Y,Tsuya A,Naito T,Murakami H,Takahashi T,Ohde Y,Kondo H,Endo M,Kameya T,Nakajima T,Mori K,Yamamoto N

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Zoledronic acid treatment reduces the incidence of skeletal-related events (SREs) in patients with bone metastases from breast, lung, and urologic cancers including prostate and renal cancer. The aim of this study was to evaluate the effect of zoledronic acid on SREs in patients with bone metastases from bla...

journal_title：International journal of clinical oncology

authors： Zaghloul MS,Boutrus R,El-Hossieny H,Kader YA,El-Attar I,Nazmy M

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma (MCC) is a rare cutaneous malignancy with a high rate of nodal metastasis. Sentinel lymph node biopsy (SLNB) is used in MCC and other cancers to identify regional node micrometastases in patients with clinically negative nodes; however, whether SLN status is associated with recurrence o...

journal_title：International journal of clinical oncology

authors： Shibayama Y,Imafuku S,Takahashi A,Nakayama J

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:No investigation of S-1 monotherapy in previously treated advanced non-small-cell lung cancer (NSCLC) patients has yet been reported. We conducted a retrospective study to evaluate the efficacy and tolerability of S-1 in patients with failure of second- or further-line chemotherapy. PATIENTS AND METHODS:The...

journal_title：International journal of clinical oncology

authors： Ono A,Naito T,Murakami H,Takahashi T,Nakamura Y,Tsuya A,Kaira K,Igawa S,Shukuya T,Tamiya A,Kaira R,Endo M,Yamamoto N

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:We have performed 26 vaginal radical trachelectomies (RTs) for patients with early invasive uterine cervical cancer since 2003 and, to date, have experienced 8 deliveries. The procedure has a high risk for preterm labor and the subsequent occurrence of preterm premature rupture of membranes (pPROM). We repor...

journal_title：International journal of clinical oncology

authors： Takada S,Ishioka S,Endo T,Baba T,Morishita M,Akashi Y,Mizuuchi M,Adachi H,Kim M,Saito T

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Testicular cancer is a rare type of cancer in males. Since the disease is seen in young men and long-term survival is ensured following a high treatment success rate, fertility in testicular cancer patients is much more important. Prior to commencement of cancer treatment, patients are given counselling with...

journal_title：International journal of clinical oncology

authors： Uçar MA,Arikan F,Coşkun HŞ,Kondak Y,Tatlı AM,Göksu SS

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Soft-tissue tumors are often accompanied by abnormal temperature distribution detected during palpation. However, the assessment of temperature distribution is subjective, limiting its wide use in cancer screening. The aim of this study was to evaluate the clinical significance of the thermal detection of so...

journal_title：International journal of clinical oncology

authors： Shimatani A,Hoshi M,Oebisu N,Iwai T,Takada N,Nakamura H

更新日期：2020-07-01 00:00:00