Time to biochemical relapse after radical prostatectomy and efficacy of salvage radiotherapy in patients with prostate cancer.

abstract：BACKGROUND:Merkel cell carcinoma (MCC) is a rare cutaneous malignancy with a high rate of nodal metastasis. Sentinel lymph node biopsy (SLNB) is used in MCC and other cancers to identify regional node micrometastases in patients with clinically negative nodes; however, whether SLN status is associated with recurrence o...

journal_title：International journal of clinical oncology

authors： Shibayama Y,Imafuku S,Takahashi A,Nakayama J

更新日期：2015-02-01 00:00:00

abstract：:We report four patients with hepatocellular carcinoma (all men, with liver cirrhosis and hepatitis C virus infections) who showed spontaneous regression of the tumor. When the spontaneous regression occurred all of the patients were over age 67 years. They showed a rapid increase of serum alpha-fetoprotein levels just...

journal_title：International journal of clinical oncology

authors： Kondo S,Okusaka T,Ueno H,Ikeda M,Morizane C

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Dendritic cell (DC)-based and cytokine-induced killer cell (CIK)-based therapy can induce specific antitumor T-cell responses. This clinical pilot study examined the safety, the feasibility, and the outcome of tumor-specific immunotherapy for patients with advanced pancreatic adenocarcinoma. METHODS:Alpha-G...

journal_title：International journal of clinical oncology

authors： Qiu Y,Yun MM,Xu MB,Wang YZ,Yun S

更新日期：2013-08-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Recently, the incidence of oropharyngeal cancer (OPC) has increased markedly in comparison to that of HNSCC, which is associated with the use of tobacco or alcohol or both. This increase has resulted mainly from the global rise in...

journal_title：International journal of clinical oncology

authors： Sano D,Oridate N

更新日期：2016-10-01 00:00:00

abstract：:Stereotactic body radiation therapy (SBRT) can yield excellent local tumor control, as well as survival benefit comparable to that of surgery for early-stage lung cancer. However, in terms of toxicity, SBRT might lead to fatal radiation pneumonitis. Lung diseases, such as chronic obstructive pulmonary disease (COPD) a...

journal_title：International journal of clinical oncology

authors： Doi H,Nakamatsu K,Nishimura Y

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:The combination of a new oral dihydropyrimidine dehydrogenase-inhibitory fluoropyrimidine (S-1) and cisplatin (CDDP) is one of the most active chemotherapy regimens for gastric cancer. However, the optimum schedule for this combination has not yet been determined. This study was conducted to establish the ma...

journal_title：International journal of clinical oncology

authors： Sato Y,Kondo H,Honda K,Takahari D,Sumiyoshi T,Tsuji Y,Yoshizaki N,Niitsu Y

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:We aimed to determine the safety and efficacy of monthly paclitaxel and carboplatin with oral estramustine phosphate in patients with hormone-refractory prostate cancer (HRPC). METHODS:Patients with prostate cancer that was progressing despite androgen ablation therapy were treated with i.v. paclitaxel, 175...

journal_title：International journal of clinical oncology

authors： Segawa T,Kamoto T,Kinoshita H,Kunishima Y,Yoshimura K,Ito A,Takahashi T,Higashi S,Nakamura E,Nishiyama H,Ito N,Yamamoto S,Habuchi T,Ogawa O

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Soft-tissue tumors are often accompanied by abnormal temperature distribution detected during palpation. However, the assessment of temperature distribution is subjective, limiting its wide use in cancer screening. The aim of this study was to evaluate the clinical significance of the thermal detection of so...

journal_title：International journal of clinical oncology

authors： Shimatani A,Hoshi M,Oebisu N,Iwai T,Takada N,Nakamura H

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:We retrospectively analyzed the clinicopathological features and evaluated the prognostic indicators of recurrence in 132 patients with clear cell adenocarcinoma (CCC) of the ovary at reproductive age. PATIENTS AND METHODS:Between 1986 and 2011, as a regional population-based study, clinicopathological data...

journal_title：International journal of clinical oncology

authors： Kajiyama H,Mizuno M,Shibata K,Umezu T,Suzuki S,Yamamoto E,Mitsui H,Sekiya R,Niimi K,Kawai M,Nagasaka T,Kikkawa F

更新日期：2014-10-01 00:00:00

abstract：:Combination chemotherapy with cisplatin and pemetrexed is the most active first-line regimen for malignant pleural mesothelioma (MPM). However, no drugs have been approved for second-line treatment of MPM, with effective regimens remaining to be identified for patients in relapse. We have now evaluated the combination...

journal_title：International journal of clinical oncology

authors： Hayashi H,Okamoto I,Ichikawa Y,Miyazaki M,Yoshioka H,Kunimasa K,Nakagawa K

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:An association between inflammation and patient prognosis has been reported in various types of cancer. The aim of this study was to evaluate the influence of preoperative biliary drainage-related inflammation in patients with biliary tract cancer. METHODS:The clinical data of 97 patients who underwent surg...

journal_title：International journal of clinical oncology

authors： Kurahara H,Maemura K,Mataki Y,Sakoda M,Iino S,Kawasaki Y,Arigami T,Uenosono Y,Kijima Y,Shinchi H,Takao S,Natsugoe S

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:This multi-center, phase III trial assesses the efficacy of daikenchuto (TU-100) on gastrointestinal disorders after hepatic resection (UMIN Registration No. 000003103). MATERIALS AND METHODS:A total of 231 patients, who underwent hepatic resection at 26 Japanese centers, were enrolled. Patients were random...

journal_title：International journal of clinical oncology

authors： Shimada M,Morine Y,Nagano H,Hatano E,Kaiho T,Miyazaki M,Kono T,Kamiyama T,Morita S,Sakamoto J,Kusano M,Saji S,Kanematsu T,Kitajima M

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Total pharyngolaryngectomy (TPL) is a conventional and standard surgical method for locoregional control of advanced hypopharyngeal cancer (HPC). This study aimed to define the clinicopathological prognostic factors of TPL by evaluating our surgical experience of TPL in the treatment of HPCs. METHODS:We ret...

journal_title：International journal of clinical oncology

authors： Omura G,Ando M,Saito Y,Kobayashi K,Yamasoba T,Asakage T

更新日期：2015-04-01 00:00:00

abstract：:A 45-year-old woman with HER2(-)/HER1(-) breast cancer underwent radical mastectomy, followed by radiation and chemotherapy. However, her symptoms progressed rapidly owing to meningitis carcinomatosa and she was fitted with a urethral catheter. She also had difficulty in walking. However, immediately after treatment w...

journal_title：International journal of clinical oncology

authors： Onishi H,Morisaki T,Nakafusa Y,Nakashima Y,Yokohata K,Katano M

更新日期：2011-12-01 00:00:00

abstract：:We report the case of a 59-year-old man with advanced renal cell carcinoma (RCC), without inferior vena cava (IVC) involvement, treated with radical nephrectomy, palliative radiotherapy for bone metastasis, and medical therapy for bone and lung metastases. The patient died of cardiac arrest after evidence of massive m...

journal_title：International journal of clinical oncology

authors： Zustovich F,Gottardo F,De Zorzi L,Cecchetto A,Dal Bianco M,Mauro E,Cartei G

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:We aimed to determine the frequency of fibromyalgia syndrome (FM) in operated breast cancer patients and to research the relationship between FM and the severity of fatigue and quality of life in these breast cancer patients. METHODS:The demographic data of 101 operated breast cancer patients were recorded....

journal_title：International journal of clinical oncology

authors： Akkaya N,Atalay NS,Selcuk ST,Alkan H,Catalbas N,Sahin F

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:We aimed to compare the impact of systematic uncertainties in patient setup and prostate motion on three different external-beam radiotherapy protocols for prostate cancer. METHODS:To simulate possible near-maximum systematic errors, the isocenter position was shifted to eight points with +/-1.65 SD of the ...

journal_title：International journal of clinical oncology

authors： Zhu SY,Mizowaki T,Norihisa Y,Takayama K,Nagata Y,Hiraoka M

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Hormone receptor status has been one of the most important factors in predicting the response to endocrine therapy in breast cancer patients. However, half of those patients with estrogen receptor-positive tumors do not respond to endocrine therapy. There have been no universal factors for predicting resista...

journal_title：International journal of clinical oncology

authors： Kai K,Nishimura R,Arima N,Miyayama H,Iwase H

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:The clinical impact of monitoring serum p53 antibodies, carbohydrate antigen19-9, and carcinoembryonic antigen in patients with colorectal cancer has not been fully evaluated. METHODS:A total of 420 surgically treated stage II/III colorectal cancer patients were retrospectively analyzed. Among them, 101 pat...

journal_title：International journal of clinical oncology

authors： Ushigome M,Shimada H,Miura Y,Yoshida K,Kaneko T,Koda T,Nagashima Y,Suzuki T,Kagami S,Funahashi K

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Because there are few exchanges of doctors and surgical techniques among leading Japanese hospitals, neck dissections in Japan have become so highly diverse that the uniformity and comparability of nonradical neck dissections have become questionable. METHODS:The Japan Neck Dissection Study Group (JNDSG) wa...

journal_title：International journal of clinical oncology

authors： Saikawa M,Kishimoto S

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Impact of R1 (microscopically margin-positive) resection on survival of patients with hepatoblastoma (HB) remains debatable. This study aimed to compare the long-term outcomes of R0 (microscopically margin-negative) and R1 resection for HB in children after hepatectomy. METHODS:We retrospectively reviewed f...

journal_title：International journal of clinical oncology

authors： Ren X,Li H,Diao M,Xu H,Li L

更新日期：2020-04-01 00:00:00

abstract：:The two main malignant hepatic tumors in children are hepatoblastomas (HBLs) and hepatocellular carcinomas (HCCs). The past two decades have brought significant improvement to the outcomes of children diagnosed with malignant hepatic tumors, especially HBL, due to improvements in diagnosis and treatment. Histological ...

journal_title：International journal of clinical oncology

authors： Hiyama E

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:To analyze the impact of sunitinib treatment on health-related quality of life (HRQOL) in Japanese patients with metastatic renal cell carcinoma (mRCC). METHODS:This study prospectively included 90 consecutive patients with mRCC treated with sunitinib for at least 3 months. HRQOL in these patients was asses...

journal_title：International journal of clinical oncology

authors： Miyake H,Harada K,Kusuda Y,Fujisawa M

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the predictive value of preoperative hydronephrosis for pathological outcome and prognosis in patients with upper tract urothelial carcinoma treated with nephroureterectomy. METHODS:167 patients with UTUC treated with nephroureterectomy at our two institutions in Japan between 2002 and 2017 were ...

journal_title：International journal of clinical oncology

authors： Fukui T,Kanno T,Kobori G,Moroi S,Yamada H

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Panitumumab is a fully human, monoclonal antibody against the epidermal growth factor receptor. Previous studies in non-Japanese patients with solid tumors showed that panitumumab exhibited nonlinear pharmacokinetics, was well tolerated (skin toxicities were the most common treatment-related adverse events),...

journal_title：International journal of clinical oncology

authors： Doi T,Ohtsu A,Tahara M,Tamura T,Shirao K,Yamada Y,Otani S,Yang BB,Ohkura M,Ohtsu T

更新日期：2009-08-01 00:00:00

abstract：:Prostate cancer is androgen-dependent, and hormone therapy, mainly achieved by androgen deprivation, has been one of the main treatment modalities in the clinical management of prostate cancer patients for more than six decades. In the 1980s, luteinizing hormone-releasing hormone agonists, which reduce testosterone to...

journal_title：International journal of clinical oncology

authors： Suzuki H,Kamiya N,Imamoto T,Kawamura K,Yano M,Takano M,Utsumi T,Naya Y,Ichikawa T

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Whether the administration of calcium (Ca) and magnesium (Mg) can reduce oxaliplatin-related neurotoxicity remains controversial. In addition, little is known about the effects of Ca/Mg on the blood level of platinum or objective tumor progression. PATIENTS AND METHODS:Patients receiving modified FOLFOX6 fo...

journal_title：International journal of clinical oncology

authors： Ishibashi K,Okada N,Miyazaki T,Sano M,Ishida H

更新日期：2010-02-01 00:00:00

abstract：:Sarcomas represent a rare and heterogeneous disease and the prognosis of patients remains poor, with a disease-free survival at 5 years of less than 10%. Only a few chemotherapeutic agents, such as doxorubicin and ifosfamide, have been identified to be active with response rates above 20%. The concept of angiostatic t...

journal_title：International journal of clinical oncology

authors： Kasper B,Ho AD,Egerer G

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Sternal resection is occasionally required for patients with malignant tumors, particularly sarcomas, in the sternal region. Few reports have described post-operative respiratory and shoulder function after sternal resection for patients with bone and soft-tissue sarcomas. METHODS:Eight consecutive patients...

journal_title：International journal of clinical oncology

authors： Nishida Y,Tsukushi S,Urakawa H,Toriyama K,Kamei Y,Yokoi K,Ishiguro N

更新日期：2015-12-01 00:00:00

abstract：:We present the case of a 62-year-old Japanese man whose histological diagnosis was adenoendocrine cell carcinoma of the gallbladder at autopsy, but whose antemortem diagnosis was squamous cell carcinoma. The patient was admitted to hospital with complaints of occasional vomiting and abdominal pain. Abdominal computed ...

journal_title：International journal of clinical oncology

authors： Taniguchi H,Sakagami J,Suzuki N,Hasegawa H,Shinoda M,Tosa M,Baba T,Yasuda H,Kataoka K,Yoshikawa T

更新日期：2009-04-01 00:00:00