Role of bronchoalveolar lavage diagnostics in fungal infections.

abstract：:Hypoxemia is a prevalent problem in the chronically critically ill patient. This article reviews the pathophysiologic mechanisms of hypoxemia in this patient population, discusses how oxygenation is evaluated, and reviews methods for delivery of oxygen. Other topics directly related to oxygen use, such as oxygen toxic...

journal_title：Clinics in chest medicine

authors： White AC

更新日期：2001-03-01 00:00:00

abstract：:The objectives of this article are to (1) understand how respiratory event definitions and syndrome threshold values affect prevalence estimates of obstructive sleep apnea in adults, (2) recognize important risk factors for obstructive sleep apnea in adults, and (3) understand current theories of the underlying mechan...

journal_title：Clinics in chest medicine

authors： Yaggi HK,Strohl KP

更新日期：2010-06-01 00:00:00

abstract：:Pleural effusions are a common clinical problem, yet the mechanisms of pleural fluid formation have only recently been investigated. In this article, the anatomy and physiology of the normal pleural space is discussed, as well as the pathophysiology of pleural effusion formation. ...

journal_title：Clinics in chest medicine

authors： Wiener-Kronish JP,Berthiaume Y,Albertine KH

更新日期：1985-09-01 00:00:00

abstract：:Millions of people worldwide engage in leisure or occupational activities in extreme environments. These environments entail health risks even for normal subjects. The presence of lung disease, or other conditions, further predisposes to illness or injury. Patients who have lung conditions should, but often do not, co...

journal_title：Clinics in chest medicine

authors： Dillard TA,Khosla S,Ewald FW Jr,Kaleem MA

更新日期：2005-09-01 00:00:00

abstract：:Primary graft dysfunction (PGD) is the most important cause of early morbidity and mortality following lung transplantation. PGD affects up to 25% of all lung transplant procedures and currently has no proven preventive therapy. Lung transplant recipients who recover from PGD may have impaired long-term function and a...

journal_title：Clinics in chest medicine

authors： Lee JC,Christie JD

更新日期：2011-06-01 00:00:00

abstract：:The adult respiratory distress syndrome is a reaction of the lung to a variety of severe direct or indirect pulmonary insults. It is characterized by acute respiratory distress, severe hypoxemia requiring high oxygen fractions, and "stiff lungs" requiring approaches to ventilatory management cited elsewhere in this is...

journal_title：Clinics in chest medicine

authors： Petty TL

更新日期：1982-01-01 00:00:00

abstract：:The Hispanic population in the United States is diverse in many respects. Although there is marked variation in the prevalence, morbidity, and mortality of asthma among Hispanic subgroups in the United States, these differences are poorly understood. Future stu-dies of asthma should include large samples of Hispanic s...

journal_title：Clinics in chest medicine

authors： Cohen RT,Celedón JC

更新日期：2006-09-01 00:00:00

abstract：:Individualized management of asthma requires consideration of single or combined pharmacologic alternatives. This article reviews experimental and clinical data on the efficacy, safety, mode of action, and therapeutic indications for cromolyn and related inhalational compounds; ketotifen; alpha-adrenergic blockers; ca...

journal_title：Clinics in chest medicine

authors： Falliers CJ,Tinkelman DG

更新日期：1986-09-01 00:00:00

abstract：:Clinically apparent involvement of the heart and nervous system occurs in a relatively small number of patients with sarcoidosis. The diagnosis of myocardial and neurological sarcoidosis is difficult because anatomic presence of granulomas without clinical dysfunction is an important feature of sarcoidosis. The chest ...

journal_title：Clinics in chest medicine

authors： Sharma OP

更新日期：1997-12-01 00:00:00

abstract：:This heterogeneous group of immunologic causes of pleural effusions includes connective tissue diseases, a syndrome related to tissue injury (postcardiac injury syndrome), a disease of unknown etiology (sarcoidosis), a malignancy, and adverse reactions to drugs. Except in rheumatoid pleurisy and lupus pleuritis, the p...

journal_title：Clinics in chest medicine

authors： Sahn SA

更新日期：1985-03-01 00:00:00

abstract：:Pregnancy induces significant physiologic stresses on the pulmonary and cardiovascular systems that may precipitate respiratory compromise. In addition, certain disease states that are unique to the pregnant woman, such as amniotic fluid emboli syndrome, may be associated with respiratory failure. The physiologic chan...

journal_title：Clinics in chest medicine

authors： Pereira A,Krieger BP

更新日期：2004-06-01 00:00:00

abstract：:Massive hemoptysis accounts for a minority of all patients with hemoptysis but poses a major challenge for the acute and long-term treatment. Massive hemoptysis can lead to asphyxiation and airway obstruction, shock, and exsanguination. Bronchoscopy plays an integral part in managing massive hemoptysis in diagnosis an...

journal_title：Clinics in chest medicine

authors： Dweik RA,Stoller JK

更新日期：1999-03-01 00:00:00

abstract：:An older smoker tends to be asked less often to quit although he or she has much to gain from achieving a nonsmoking status. Multiple barriers may interfere with attempting to quit including nicotine withdrawal, doubted self-efficacy, other smokers in one's environment, or misperceptions of little gain from quitting. ...

journal_title：Clinics in chest medicine

authors： Cox JL

更新日期：1993-09-01 00:00:00

abstract：:Airway inflammation due to exposure to a wide variety of agents encountered in the workplace is a major cause of occupational asthma. This article reviews major examples of occupational asthma linked to airway inflammation, including their epidemiology, pathophysiology, and clinical course. ...

journal_title：Clinics in chest medicine

authors： Fine JM,Balmes JR

更新日期：1988-12-01 00:00:00

abstract：:Although they are complex, the pulmonary-renal syndromes can be readily understood and managed using a clinical approach firmly grounded in the fundamental pathophysiology of these disorders. Several important principles must be borne in mind. First, therapeutic intervention must be preceded by making as firm a diagno...

journal_title：Clinics in chest medicine

authors： Young KR Jr

更新日期：1989-12-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) has become a major and growing health problem, with a mortality rate that continues to increase. Several factors, have been identified as individual predictors of mortality in COPD. This article reviews individual predictors for mortality. It also discusses the ability of a...

journal_title：Clinics in chest medicine

authors： Cote CG,Celli BR

更新日期：2007-09-01 00:00:00

abstract：:Lung cancer is a leading cause of cancer-related death in the world, and it accounts for more deaths than breast, colon, and prostate cancer combined in the United States. From a historical perspective, the premise behind early lung cancer detection strategy is that early detection of lung cancer is justified if early...

journal_title：Clinics in chest medicine

authors： Colt HG,Murgu SD

更新日期：2010-03-01 00:00:00

abstract：:This article focuses on thoracoscopy for pleural procedures, both diagnostic and therapeutic, and discusses whether there is a difference between pleuroscopy and thoracoscopy or video-assisted thoracic surgery. How thinking should be structured regarding the management of pleural disease in the modern context of avail...

journal_title：Clinics in chest medicine

authors： Detterbeck FC

更新日期：2013-03-01 00:00:00

abstract：:The recent advances in our understanding of breathing in sleep include an evolution in the selection and surgical therapy of patients with the sleep apnea syndrome. Recent work suggests that shorter polysomnographic studies may be adequate for diagnostic purposes in many sleep apnea patients. It is now clear that cent...

journal_title：Clinics in chest medicine

authors： Kryger MH,White DP,Zwillich CW,Robinson RW,Guilleminault C

更新日期：1985-12-01 00:00:00

abstract：:The pharmacologic treatment of chronic obstructive pulmonary disease (COPD) differs from that of asthma in several respects. Oral therapy should be the keystone, using a long-acting theophylline or a beta 2-sympathomimetic agent. The addition of a metered dose inhalant aerosol provides additive benefit with low toxici...

journal_title：Clinics in chest medicine

authors： Ziment I

更新日期：1990-09-01 00:00:00

abstract：:Nonresolving pneumonia is a common and frequently misunderstood problem faced by the practicing pulmonologist. While radiographic resolution of most infections is relatively long and lags behind clinical signs of recovery, data suggest that a variety of host defense problems are a consequence of systemic illness and a...

journal_title：Clinics in chest medicine

authors： Fein AM,Feinsilver SH,Niederman MS,Fiel S,Pai PB

更新日期：1987-09-01 00:00:00

abstract：:Our ability to define appropriate molecular targets for preclinical development and develop better methods needs to be improved, to determine the clinical value of novel acute respiratory distress syndrome (ARDS) agents. Clinical trials must have realistic sample sizes and meaningful end points and use the available o...

journal_title：Clinics in chest medicine

authors： Curley GF,McAuley DF

更新日期：2014-12-01 00:00:00

abstract：:Occupational and environmental exposures contribute to the development and progression of most lung diseases, yet their impact is greatly under-recognized in clinical practice. Clinicians caring for patients with respiratory diseases should maintain a high index of suspicion for occupational and environmental contribu...

journal_title：Clinics in chest medicine

authors： James E,Linde B,Redlich CA

更新日期：2020-12-01 00:00:00

abstract：:Each year, a vast number of individuals are infected with the endemic fungi. An expanding population, along with further land development in endemic areas, will likely continue to place individuals at risk for exposure to these organisms. A high index of suspicion may be required to diagnose histoplasmosis, blastomyco...

journal_title：Clinics in chest medicine

authors： Goldman M,Johnson PC,Sarosi GA

更新日期：1999-09-01 00:00:00

abstract：:Studies suggest clinically manifest cardiac involvement occurs in 5% of patients with pulmonary/systemic sarcoidosis. The principal manifestations of cardiac sarcoidosis (CS) are conduction abnormalities, ventricular arrhythmias, and heart failure. Data indicate that an 20% to 25% of patients with pulmonary/systemic s...

journal_title：Clinics in chest medicine

authors： Birnie D,Ha AC,Gula LJ,Chakrabarti S,Beanlands RS,Nery P

更新日期：2015-12-01 00:00:00

abstract：:This article assesses the role of pharmacotherapy in the management of respiratory muscle dysfunction. It focuses on two classes of drugs, the methylxanthines and the sympathomimetic agents. A prospective section focuses also on the particularities of the diaphragm among the skeletal striated muscles. In addition, a n...

journal_title：Clinics in chest medicine

authors： Aubier M

更新日期：1988-06-01 00:00:00

abstract：:The Early Goal-Directed Therapy versus Standard Care for Sepsis trial by Rivers and colleagues in 2001 suggested that a significant mortality reduction may be realized through goal-directed interventions early in the care of patients with septic shock. However, the recent publication of the Protocol-Based Care for Ear...

journal_title：Clinics in chest medicine

authors： Henning DJ,Shapiro NI

更新日期：2016-06-01 00:00:00

abstract：:In the past it was believed that respiratory disability could be objectively assessed by comparing the measured O2 consumption requirement of the job with the subjects' measured or estimated maximal oxygen consumption. More recently, it has become clear that this "classic" paradigm does not completely apply to all sit...

journal_title：Clinics in chest medicine

authors： Harber P

更新日期：1992-06-01 00:00:00

abstract：:There will be many changes in the sleep field in the next 5 to 10 years. These will include increments in our knowledge of the basic neurobiologic mechanisms driving sleep and the impact of sleep loss on general health. The technology used in the sleep laboratory will likely change as well, leading to a larger range o...

journal_title：Clinics in chest medicine

authors： White DP

更新日期：1998-03-01 00:00:00

abstract：:The most common causes for undiagnosed transudative effusions are congestive heart failure and hepatic hydrothorax. Pleural fluid N terminal pro-brain natriuretic peptide levels higher than 1500 pg/mL are virtually diagnostic of congestive heart failure. The most common causes for undiagnosed exudative pleural effusio...

journal_title：Clinics in chest medicine

authors： Light RW

更新日期：2006-06-01 00:00:00