Interventional bronchoscopy from bench to bedside: new techniques for early lung cancer detection.

abstract：:Because of physiologic changes associated with aging and the development of chronic illness, the elderly will continue to be at risk for catastrophic illnesses including adult respiratory distress syndrome (ARDS). Current management of elderly patients with ARDS is only supportive and focused on avoiding complications...

journal_title：Clinics in chest medicine

authors： Griffith D,Idell S

更新日期：1993-09-01 00:00:00

abstract：:Our understanding of chronic bronchitis has been hampered by the fact that the diagnosis is based upon historical evidence of recurrent cough and sputum without any requirement that certain physiologic or microscopic criteria be met. Despite the fact that epidemiological studies have implicated viruses, bacteria, and ...

journal_title：Clinics in chest medicine

authors： Sachs FL

更新日期：1981-01-01 00:00:00

abstract：:Pleural malignancies are ideal for novel therapeutic approaches because they are invariably fatal. Intrapleural (IP) chemotherapy has only marginal benefit in pleural malignancies, but may prove efficacious with hyperthermic chemotherapy administered in combination with maximal tumor debulking. IP immunotherapies may ...

journal_title：Clinics in chest medicine

authors： Haas AR,Sterman DH

更新日期：2013-09-01 00:00:00

abstract：:Sleep-related breathing disorders are strongly associated with increased risk of stroke independent of known risk factors. The direction of causation favors sleep-disordered breathing leading to stroke rather than the other way around, although definitive proof of this awaits the results of prospective cohort studies....

journal_title：Clinics in chest medicine

authors： Yaggi H,Mohsenin V

更新日期：2003-06-01 00:00:00

abstract：:In the United States, trauma is the leading cause of death in people under 40 years of age. Chest trauma is a relatively common but potentially lethal injury and requires a high level of suspicion, rapid diagnosis, and appropriate therapy. Methods for the assessment, diagnosis, and treatment of chest trauma are discus...

journal_title：Clinics in chest medicine

authors： Kshettry VR,Bolman RM 3rd

更新日期：1994-03-01 00:00:00

abstract：:Bacterial pneumonias occur with increased frequency and can be associated with increased morbidity in the HIV-infected population compared with normals. The pathogens that most frequently cause community-acquired pneumonias are S. pneumoniae, H. influenzae, and occasionally S. aureus. These pneumonias usually respond ...

journal_title：Clinics in chest medicine

authors： Fels AO

更新日期：1988-09-01 00:00:00

abstract：:The older adult demonstrates several alterations in the ventilatory response to exercise relative to the young adult. These differences are primarily caused by the aging-induced loss of elastic recoil of the lung, which reduces expiratory airflow rates along the effort-independent portion of the maximal volitional flo...

journal_title：Clinics in chest medicine

authors： Johnson BD,Badr MS,Dempsey JA

更新日期：1994-06-01 00:00:00

abstract：:The most common causes for undiagnosed transudative effusions are congestive heart failure and hepatic hydrothorax. Pleural fluid N terminal pro-brain natriuretic peptide levels higher than 1500 pg/mL are virtually diagnostic of congestive heart failure. The most common causes for undiagnosed exudative pleural effusio...

journal_title：Clinics in chest medicine

authors： Light RW

更新日期：2006-06-01 00:00:00

abstract：:Polymerase chain reaction-based diagnosis has become the standard for viral pneumonia and other respiratory tract infections. Expansion of respiratory viral panels (RVPs) outside of influenza and, possibly, respiratory syncytial virus has led to the ability to diagnose viral infections for which no approved specific a...

journal_title：Clinics in chest medicine

authors： Wunderink RG

更新日期：2017-03-01 00:00:00

abstract：:This article reviews aspects of mechanical ventilation in patients without lung injury, patients in the perioperative period, and those with neurologic injury or disease including spinal cord injury. Specific emphasis is placed on ventilator strategies, including timing and indications for tracheostomy. Lung protectiv...

journal_title：Clinics in chest medicine

authors： Bowton DL,Scott LK

更新日期：2016-12-01 00:00:00

abstract：:Given that poor asthma management leads to such devastating rates of morbidity and mortality in this country, efforts must be made to increase the knowledge, skills, and behaviors of persons with asthma. The suggestions and recommendations provided here represent a blend of academic opinion and practical advice on met...

journal_title：Clinics in chest medicine

authors： Kohler CL,Davies SL,Bailey WC

更新日期：1995-12-01 00:00:00

abstract：:Continuous mechanical ventilation used for life support is accepted as standard practice in nearly every hospital in the United States today. The history of the evolution of techniques that we take virtually for granted today is fascinating. This article recounts some of the highlights in the development of modern-day...

journal_title：Clinics in chest medicine

authors： Marini JJ

更新日期：1988-03-01 00:00:00

abstract：:The pathogenic importance of cytomegalovirus (CMV) infection in AIDS-associated pneumonitis is controversial. Uncertainty regarding the significance of CMV isolation from pulmonary secretions of AIDS patients results in part from the difficulty in distinguishing CMV infection from CMV disease and from the high frequen...

journal_title：Clinics in chest medicine

authors： Jacobson MA,Mills J

更新日期：1988-09-01 00:00:00

abstract：:Inhaled corticosteroids (ICS) have led to improved asthma control and reduced asthma mortality in the Western world. ICS are effective in combating T-helper type 2-driven inflammation featuring mast cell and eosinophilic airway infiltration. Their effect on innate immunity-driven neutrophilic inflammation is poor and ...

journal_title：Clinics in chest medicine

authors： Louis R,Schleich F,Barnes PJ

更新日期：2012-09-01 00:00:00

abstract：:Pulmonary function testing (PFT) is used extensively by pulmonary specialists to address two common clinical questions: (1) What is the risk of a postoperative pulmonary complication in an individual with lung disease? and (2) Will the patient be able to tolerate lung resection surgery? Today, there are numerous tests...

journal_title：Clinics in chest medicine

authors： Powell CA,Caplan CE

更新日期：2001-12-01 00:00:00

abstract：:Traditional tuberculosis (TB) infection control focuses on the known patient with TB, usually on appropriate treatment. A refocused, intensified TB infection control approach is presented. Combined with active case finding and rapid molecular diagnostics, an approach called FAST is described as a convenient way to cal...

journal_title：Clinics in chest medicine

authors： Nardell EA

更新日期：2019-12-01 00:00:00

abstract：:Nonresolving pneumonia is a common and frequently misunderstood problem faced by the practicing pulmonologist. While radiographic resolution of most infections is relatively long and lags behind clinical signs of recovery, data suggest that a variety of host defense problems are a consequence of systemic illness and a...

journal_title：Clinics in chest medicine

authors： Fein AM,Feinsilver SH,Niederman MS,Fiel S,Pai PB

更新日期：1987-09-01 00:00:00

abstract：:In the past decade, there have been more patients with congenital heart disease (CHD) surviving to adulthood; whether due to late repair, or complex underlying CHD, many of these patients will be faced with pulmonary arterial hypertension (PAH) associated with CHD (APAH-CHD). In this review, the authors discuss the mo...

journal_title：Clinics in chest medicine

authors： Krishnan U,Rosenzweig EB

更新日期：2013-12-01 00:00:00

abstract：:In summary, the evaluation of the tired patient requires an awareness of the various meanings of tiredness. Furthermore, it is important to differentiate normal sleepiness that is a product of circadian rhythm variation in vigilance from pathologic sleepiness. Sleepiness that results from faulty habits, e.g., altered ...

journal_title：Clinics in chest medicine

authors： Moldofsky H

更新日期：1992-09-01 00:00:00

abstract：:Lung function testing has undisputed value in the comprehensive assessment and individualized management of chronic obstructive pulmonary disease, a pathologic condition in which a functional abnormality, poorly reversible expiratory airway obstruction, is at the core of its definition. After an overview of the physio...

journal_title：Clinics in chest medicine

authors： Neder JA,de-Torres JP,Milne KM,O'Donnell DE

更新日期：2020-09-01 00:00:00

abstract：:Chronic lung diseases, including chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH), are unusually prevalent among persons infected with human immunodeficiency virus (HIV). Often these disease states are identified at younger ages than would be expected in the general population. Recent epide...

journal_title：Clinics in chest medicine

authors： Fitzpatrick M,Crothers K,Morris A

更新日期：2013-06-01 00:00:00

abstract：:Cellular dysfunction is a commonplace sequelum of sepsis and other systemic inflammatory conditions. Impaired energy production (related to mitochondrial inhibition, damage, and reduced protein turnover) appears to be a core mechanism underlying the development of organ dysfunction. The reduction in energy availabilit...

journal_title：Clinics in chest medicine

authors： Singer M

更新日期：2008-12-01 00:00:00

abstract：:Bronchiectasis is a persistent and progressive condition characterized by inflammation and infection causing damage that potentiates impaired mucociliary clearance. The rationale for promoting airway clearance is so that purulent secretions are removed from the airways, ameliorating the inflammation and improving cont...

journal_title：Clinics in chest medicine

authors： Flude LJ,Agent P,Bilton D

更新日期：2012-06-01 00:00:00

abstract：:Controversy over the use of inhaled beta-agonists has dated almost from their introduction as a treatment for asthma. Their effectiveness as bronchodilators is not disputed, but there is concern that they may worsen asthma control if used regularly and that excessive use may increase the risk of death from asthma. Fiv...

journal_title：Clinics in chest medicine

authors： Fahy JV,Boushey HA

更新日期：1995-12-01 00:00:00

abstract：:Pleural effusions are a common clinical problem, yet the mechanisms of pleural fluid formation have only recently been investigated. In this article, the anatomy and physiology of the normal pleural space is discussed, as well as the pathophysiology of pleural effusion formation. ...

journal_title：Clinics in chest medicine

authors： Wiener-Kronish JP,Berthiaume Y,Albertine KH

更新日期：1985-09-01 00:00:00

abstract：:The treatment of idiopathic pulmonary fibrosis (IPF) remains controversial. The benefits of conventional treatment with corticosteroids plus either azathioprine or cyclophosphamide have not been established in randomized, controlled trials. Other treatment strategies have been suggested as understanding of the pathoge...

journal_title：Clinics in chest medicine

authors： Nathan SD

更新日期：2006-03-01 00:00:00

abstract：:Hemodynamic monitoring is a diagnostic tool. Because hemodynamic monitoring often requires invasive procedures, it can be associated with an increased incidence of untoward events. Like any diagnostic tool, its ability to improve outcome will be primarily related to the survival benefit enjoyed by specific therapies t...

journal_title：Clinics in chest medicine

authors： Pinsky MR

更新日期：2003-12-01 00:00:00

abstract：:Tobacco dependency syndrome is an organic disease caused by chronic use of inhaled tobacco smoke. It is occasionally controlled by willpower alone, but often requires pharmacotherapy in conjunction with various techniques to manage the psychological manifestations. The two effective drugs are bupropion, which is an or...

journal_title：Clinics in chest medicine

authors： Lillington GA,Leonard CT,Sachs DP

更新日期：2000-03-01 00:00:00

abstract：:A variety of mechanical devices may be used to provide assistance when ventilation and cough are severely impaired by progressive respiratory weakness caused by neuromuscular disease. Traditionally, positive pressure ventilation via a tracheostomy has been used, but if upper airway function is adequate, a variety of n...

journal_title：Clinics in chest medicine

authors： Unterborn JN,Hill NS

更新日期：1994-12-01 00:00:00

abstract：:As parenchymal lung disease in chronic obstructive pulmonary disease becomes increasingly severe there is a diminishing prospect of drug therapies conferring clinically useful benefit. Lung volume reduction surgery is effective in patients with heterogenous upper zone emphysema and reduced exercise tolerance, and is p...

journal_title：Clinics in chest medicine

authors： Murphy PB,Zoumot Z,Polkey MI

更新日期：2014-03-01 00:00:00