Abstract:
:As parenchymal lung disease in chronic obstructive pulmonary disease becomes increasingly severe there is a diminishing prospect of drug therapies conferring clinically useful benefit. Lung volume reduction surgery is effective in patients with heterogenous upper zone emphysema and reduced exercise tolerance, and is probably underused. Rapid progress is being made in nonsurgical approaches to lung volume reduction, but use outside specialized centers cannot be recommended presently. Noninvasive ventilation given to patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease reduces mortality and morbidity, but the place of chronic non-invasive ventilatory support remains more controversial.
journal_name
Clin Chest Medjournal_title
Clinics in chest medicineauthors
Murphy PB,Zoumot Z,Polkey MIdoi
10.1016/j.ccm.2013.10.011subject
Has Abstractpub_date
2014-03-01 00:00:00pages
251-69issue
1eissn
0272-5231issn
1557-8216pii
S0272-5231(13)00166-4journal_volume
35pub_type
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