Abstract：
:Occurrence of estrone, estradiol, and testosterone glucuronyltranferase activities was tested in a well-differentiated hepatoma, Reuber H35. Transferase activities for estrone and estradiol were found in the hepatoma. The Michaelis-Menten kinetics of these two microsomal glucuronyltransferase activities were similar in hepatoma and in liver preparations, except for a somewhat higher apparent Km for estradiol in the hepatoma preparations. Under the same experimental conditions, only trace amounts of testosterone glucuronyltransferase activity could be detected in the hepatoma preparations. By contrast, in liver microsomal preparations, testosterone glucuronyltransferase activity was the highest among the steroid glucuronyltransferase activities tested.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Gessner Tsubject
Has Abstractpub_date
1977-07-01 00:00:00pages
2275-81issue
7 Pt 1eissn
0008-5472issn
1538-7445journal_volume
37pub_type
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