当前位置： SCI文献检索 > BIOLOGICAL PSYCHIATRY期刊下所有文献 > Limbic/mesolimbic connections and the pathogenesis of schizophrenia.

Limbic/mesolimbic connections and the pathogenesis of schizophrenia.

Abstract：

:The development of models of the pathogenesis of neuropsychiatric diseases that build on recent advances in chemical neuroanatomy will help to guide future research. The interconnections among limbic, basal ganglia, and cortical structures are used to form the basis of a hypothesis of the pathogenesis of schizophrenia. The adaptive capacity of subcortical dopamine systems is advanced as an explanation of the many states of the disease.

journal_name

Biol Psychiatry

journal_title

Biological psychiatry

authors

Csernansky JG,Murphy GM,Faustman WO

doi

10.1016/0006-3223(91)90295-w

subject

Has Abstract

pub_date

1991-08-15 00:00:00

pages

383-400

issue

4

eissn

0006-3223

issn

1873-2402

pii

0006-3223(91)90295-W

journal_volume

30

pub_type

杂志文章,评审

相关文献

BIOLOGICAL PSYCHIATRY文献大全
  • Erythrocyte acetylcholinesterase in psychiatric disorders and controls.

    abstract：:Acetylcholinesterase (AChE) from erythrocytes was solubilized by Triton X-100. Size and charge heterogeneity of AChE was investigated by polyacrylamide gel electrophoresis (PAGE) and isoelectric focusing (IEF) in polyacrylamide gels in the presence of 0.5% (v/v) Triton X-100. There were no interindividual differences ...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/0006-3223(87)90052-7

    authors： Fritze J,Beckmann H

    更新日期：1987-09-01 00:00:00

  • Lack of effects of hospitalization and oral contraceptives on DST results in control subjects.

    abstract：:The effect of oral contraceptive use and hospitalization stress on the results of the dexamethasone suppression test (DST) were assessed. This test, in which 1 mg dexamethasone is given at 11:00 p.m., and blood cortisol is analyzed the following day, is used as an indicator or major or endogenous depression, as oppos...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/0006-3223(87)90113-2

    authors： D'haenen H,de Weert D,Ansseau M

    更新日期：1987-12-01 00:00:00

  • Combination of inositol and serotonin reuptake inhibitors in the treatment of depression.

    abstract：BACKGROUND:Inositol has been reported to be an effective treatment in depression, and we hypothesized that inositol addition might enhance or speed up response to serotonin selective reuptake inhibitors (SSRI). METHODS:Twenty-seven depressed patients completed a double-blind controlled 4-week trial of SSRI plus placeb...

    journal_title：Biological psychiatry

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0006-3223(98)00145-0

    authors： Levine J,Mishori A,Susnosky M,Martin M,Belmaker RH

    更新日期：1999-02-01 00:00:00

  • Relationship of dysfunctional attitudes and dexamethasone response in endogenous and nonendogenous depression.

    abstract：:Taken as a whole the data presented provide support for Klein's conceptualization of etiologically distinct subtypes of depression. A basic limbic system derangement in endogenous depression is suggested by the higher incidence of DST nonsuppression. Beck's theory that all depressions result from a primary cognitive d...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：

    authors： Giles DE,Rush AJ

    更新日期：1982-11-01 00:00:00

  • Impact of ADHD on the neurocognitive functioning of adolescents with bipolar disorder.

    abstract：BACKGROUND:Pediatric Bipolar Disorder (BD) has been associated with a number of neurocognitive deficits not dissimilar to ADHD. This study compared neuropsychological profiles of 4 groups of adolescents (14-17 years): 41 Normal Controls (NC), 30 ADHD, 12 BD and 12 combined (BD+ADHD). METHODS:Participants were identifi...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.biopsych.2006.03.067

    authors： Rucklidge JJ

    更新日期：2006-11-01 00:00:00

  • Increased dopamine D2/D3 receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [11c]raclopride.

    abstract：BACKGROUND:Several lines of evidence support the possibility that disturbances of dopamine (DA) function could contribute to alterations of weight, feeding, motor activity, and reward in anorexia nervosa (AN). METHODS:To assess possibly trait-related disturbances but avoid confounding effects of malnutrition, 10 women...

    journal_title：Biological psychiatry

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.biopsych.2005.05.003

    authors： Frank GK,Bailer UF,Henry SE,Drevets W,Meltzer CC,Price JC,Mathis CA,Wagner A,Hoge J,Ziolko S,Barbarich-Marsteller N,Weissfeld L,Kaye WH

    更新日期：2005-12-01 00:00:00

  • The Functional Brain Organization of an Individual Allows Prediction of Measures of Social Abilities Transdiagnostically in Autism and Attention-Deficit/Hyperactivity Disorder.

    abstract：BACKGROUND:Autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD) are associated with complex changes as revealed by functional magnetic resonance imaging. To date, neuroimaging-based models are not able to characterize individuals with sufficient sensitivity and specificity. Further, although evi...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.biopsych.2019.02.019

    authors： Lake EMR,Finn ES,Noble SM,Vanderwal T,Shen X,Rosenberg MD,Spann MN,Chun MM,Scheinost D,Constable RT

    更新日期：2019-08-15 00:00:00

  • Serum iron in catatonic and noncatatonic psychotic patients.

    abstract：BACKGROUND:Since low serum iron has been reported in a variety of neuropsychiatric motor disorders, this study was conducted to examine serum iron in patients with a catatonic disorder. METHODS:Forty catatonic and 40 noncatatonic psychotic patients were studied in relation to serum iron levels. The association of seru...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/s0006-3223(98)00137-1

    authors： Peralta V,Cuesta MJ,Mata I,Serrano JF,Perez-Nievas F,Natividad MC

    更新日期：1999-03-15 00:00:00

  • Electrophysiological findings during the menstrual cycle in women with and without late luteal phase dysphoric disorder: relationship to risk for alcoholism?

    abstract：:This study evaluated electrophysiological (EEG, ERGs), and cognitive (neuropsychological testing) responses in patients with late luteal phase dysphoric disorder (LLPDD, DSM-III-R) and controls over the menstrual cycle. In both groups, the frequency and stability of electroencephalogram (EEG) alpha activity significan...

    journal_title：Biological psychiatry

    pub_type： 临床试验,杂志文章

    doi：10.1016/0006-3223(95)00183-2

    authors： Ehlers CL,Phillips E,Parry BL

    更新日期：1996-04-15 00:00:00

  • A segregation study of panic disorder in families of panic patients responsive to the 35% CO2 challenge.

    abstract：BACKGROUND:A genetic component has a role in the etiology of Panic Disorder (PD) and a familial association between PD and CO2 hypersensitivity have been repeatedly described. METHODS:Complex segregation analysis was performed on a sample of 165 families of PD probands and on the subgroup homogeneous for CO2 hypersens...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/s0006-3223(99)00004-9

    authors： Cavallini MC,Perna G,Caldirola D,Bellodi L

    更新日期：1999-09-15 00:00:00

  • Stress as a common risk factor for obesity and addiction.

    abstract：:Stress is associated with obesity, and the neurobiology of stress overlaps significantly with that of appetite and energy regulation. This review will discuss stress, allostasis, the neurobiology of stress and its overlap with neural regulation of appetite, and energy homeostasis. Stress is a key risk factor in the de...

    journal_title：Biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/j.biopsych.2013.01.032

    authors： Sinha R,Jastreboff AM

    更新日期：2013-05-01 00:00:00

  • Disturbed circadian core body temperature rhythm and sleep disturbance in school refusal children and adolescents.

    abstract：:We examined the circadian rhythm of core body temperature (CBT) in 22 school refusal patients, ages between 12 and 18 years, who did not have any physical or psychiatric disorders, but had indefinite complaints, and were suspected to have a circadian rhythm disturbance. To obtain normal data for analysis, CBT in 9 hea...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/S0006-3223(96)00179-5

    authors： Tomoda A,Miike T,Yonamine K,Adachi K,Shiraishi S

    更新日期：1997-04-01 00:00:00

  • Effects of chronic lithium treatment on protein kinase C and cyclic AMP-dependent protein phosphorylation.

    abstract：:Lithium inhibits the agonist-induced hydrolysis of phosphoinositides and the synthesis of cyclic AMP (cAMP) in rat brain preparations, each of which is linked to activation of specific protein kinases. Therefore, we examined the effects of chronic lithium treatment on protein kinase activities in rat hippocampus. Chro...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/0006-3223(91)91285-y

    authors： Casebolt TL,Jope RS

    更新日期：1991-02-01 00:00:00

  • Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment.

    abstract：:Hyperactivity of the hypothalamic--pituitary--adrenal (HPA) axis has been reliably observed in patients with major depression. One of the primary features of this HPA axis hyperactivity is reduced sensitivity to the inhibitory effects of the glucocorticoid dexamethasone on the production of adrenocorticotropic hormone...

    journal_title：Biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/s0006-3223(00)01088-x

    authors： Pariante CM,Miller AH

    更新日期：2001-03-01 00:00:00

  • Decreased serum amyloid beta(1-42) autoantibody levels in Alzheimer's disease, determined by a newly developed immuno-precipitation assay with radiolabeled amyloid beta(1-42) peptide.

    abstract：BACKGROUND:Autoantibodies against amyloid beta (A beta) peptide found in patients with Alzheimer's disease (AD) also occur naturally in the general population independently of the cognitive status. METHODS:We compared serum A beta(1-42) autoantibody levels (A beta(1-42)-AL) of 96 AD patients and 30 healthy elderly con...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.biopsych.2004.12.008

    authors： Brettschneider S,Morgenthaler NG,Teipel SJ,Fischer-Schulz C,Bürger K,Dodel R,Du Y,Möller HJ,Bergmann A,Hampel H

    更新日期：2005-04-01 00:00:00

  • Attention-Deficit/Hyperactivity Disorder in Offspring of Mothers With Inflammatory and Immune System Diseases.

    abstract：BACKGROUND:Prenatal inflammatory mechanisms may play a role in the pathogenesis of psychiatric disorders and could be relevant for attention-deficit/hyperactivity disorder (ADHD). We investigated maternal chronic somatic diseases with immune components as possible risk factors for ADHD in offspring. METHODS:We perform...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.biopsych.2015.11.024

    authors： Instanes JT,Halmøy A,Engeland A,Haavik J,Furu K,Klungsøyr K

    更新日期：2017-03-01 00:00:00

  • Increased cerebrospinal fluid glutamine levels in depressed patients.

    abstract：BACKGROUND:There is increasing evidence for an association between alterations of brain glutamatergic neurotransmission and the pathophysiology of affective disorders. METHODS:We studied the association between cerebrospinal fluid (CSF) metabolites, including glutamine, in unipolar and bipolar depressed patients versu...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/s0006-3223(99)00284-x

    authors： Levine J,Panchalingam K,Rapoport A,Gershon S,McClure RJ,Pettegrew JW

    更新日期：2000-04-01 00:00:00

  • Specific IgA antibody increases in schizophrenia.

    abstract：:IgA antibody levels in serum were examined in two groups of schizophrenic patients. All were diagnosed according to DSM-III-R criteria. One group of 36 males and 12 females were compared to historical controls. The other group consisted of 13 males off drugs for at least 3 months; these were compared with age- and sex...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/0006-3223(94)00176-4

    authors： Reichelt KL,Landmark J

    更新日期：1995-03-15 00:00:00

  • Incentive Processing in Persistent Disruptive Behavior and Psychopathic Traits: A Functional Magnetic Resonance Imaging Study in Adolescents.

    abstract：BACKGROUND:Children with early-onset disruptive behavior disorder (DBD), especially those with callous-unemotional traits, are at risk of developing persistent and severe adult antisocial behavior. One possible underlying mechanism for persistence is deficient reward and loss sensitivity, i.e., deficient incentive proc...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.biopsych.2014.08.017

    authors： Cohn MD,Veltman DJ,Pape LE,van Lith K,Vermeiren RR,van den Brink W,Doreleijers TA,Popma A

    更新日期：2015-11-01 00:00:00

  • Dysbindin (DTNBP1) and the biogenesis of lysosome-related organelles complex 1 (BLOC-1): main and epistatic gene effects are potential contributors to schizophrenia susceptibility.

    abstract：BACKGROUND:The DTNBP1 gene, encoding dysbindin, has been strongly implicated in schizophrenia (SZ) susceptibility by a series of independent genetic association and gene expression studies. Among its known functions, dysbindin is part of a protein complex, termed the biogenesis of lysosome-related organelles complex 1 ...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.biopsych.2006.12.025

    authors： Morris DW,Murphy K,Kenny N,Purcell SM,McGhee KA,Schwaiger S,Nangle JM,Donohoe G,Clarke S,Scully P,Quinn J,Meagher D,Baldwin P,Crumlish N,O'Callaghan E,Waddington JL,Gill M,Corvin AP

    更新日期：2008-01-01 00:00:00

  • Whole blood serotonin content, tryptophan concentrations, and impulsivity in anorexia nervosa.

    abstract：BACKGROUND:We hypothesized that anorectics with or without bulimic features would differ on impulsivity and indices of central serotoninergic function (high impulsivity being correlated with reduced serotoninergic function). METHODS:For all patients impulsivity rating scales and questionnaires detailing severity of ea...

    journal_title：Biological psychiatry

    pub_type： 临床试验,杂志文章

    doi：10.1016/S0006-3223(97)00299-0

    authors： Askenazy F,Candito M,Caci H,Myquel M,Chambon P,Darcourt G,Puech AJ

    更新日期：1998-02-01 00:00:00

  • Body weight and reported versus measured weight loss as confounders of the dexamethasone suppression test.

    abstract：:We examined the association between post-dexamethasone suppression test (DST) serum cortisol and body weight, self-report of weight loss during the episode, and measured weight loss during the first week of admission in a series of 245 depressed inpatients. Data on measured weight loss between two successive admission...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/0006-3223(86)90267-2

    authors： Pfohl B,Coryell W,Stangl D,Zimmerman M

    更新日期：1986-08-01 00:00:00

  • Developmental delay in P300 production in children at high risk for developing alcohol-related disorders.

    abstract：BACKGROUND:Reduction of P300 amplitude in children and adolescents at high risk for developing alcoholism has frequently been reported. It has been hypothesized that this reduction represents a developmental delay in reaching age-appropriate levels in P300 amplitude. Using latent growth analysis of longitudinal data ob...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/s0006-3223(99)00032-3

    authors： Hill SY,Shen S,Locke J,Steinhauer SR,Konicky C,Lowers L,Connolly J

    更新日期：1999-10-01 00:00:00

  • Schizophrenia as a disorder of molecular pathways.

    abstract：:Over the last decade, transcriptome studies of postmortem tissue from subjects with schizophrenia revealed that synaptic, mitochondrial, immune system, gamma-aminobutyric acidergic, and oligodendrocytic changes are all integral parts of the disease process. The combined genetic and transcriptomic studies argue that th...

    journal_title：Biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/j.biopsych.2014.01.001

    authors： Horváth S,Mirnics K

    更新日期：2015-01-01 00:00:00

  • Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia.

    abstract：BACKGROUND:There is an increasing recognition that the pathophysiology of mental disorders could be the result of deregulation of synaptic plasticity with alterations of neurotrophins. The valine (Val)66-to-methionine (Met) variant, located in the pro brain-derived neurotrophic factor (BDNF) sequence, has been extensiv...

    journal_title：Biological psychiatry

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.biopsych.2006.08.025

    authors： Gratacòs M,González JR,Mercader JM,de Cid R,Urretavizcaya M,Estivill X

    更新日期：2007-04-01 00:00:00

  • Effects of neuroleptics on platelet monoamine oxidase activity.

    abstract：:Platelet MAO activity in schizophrenics was significantly decreased, by about 15%, after 3 weeks of treatment with haloperidol. Treatment with thioridazine or butaperazine also tended to decrease platelet MAO activity. The neuroleptic-induced decrease began to appear within a few days of treatment and did not show tol...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：

    authors： Ho BT,Smith RC,Kralik P,Allen R,Schoolar J,Khan M,DeJohn C

    更新日期：1982-08-01 00:00:00

  • Auditory P3a deficits in male subjects at high risk for alcoholism.

    abstract：BACKGROUND:Substantial evidence indicates that alcoholism is biologically mediated by a genetic predisposition. As the decreased P300 (P3b) event-related brain potential component does not recover with prolonged abstinence, it is unlikely to be related to drinking history but is more likely to be genetically influenced...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/s0006-3223(00)01049-0

    authors： Hada M,Porjesz B,Chorlian DB,Begleiter H,Polich J

    更新日期：2001-04-15 00:00:00

  • The prevalence and correlates of nonaffective psychosis in the National Comorbidity Survey Replication (NCS-R).

    abstract：BACKGROUND:To estimate the prevalence and correlates of clinician-diagnosed DSM-IV nonaffective psychosis (NAP) in a national household survey. METHODS:Data came from the United States National Comorbidity Survey Replication (NCS-R). A screen for NAP was followed by blinded sub-sample clinical reappraisal interviews. ...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.biopsych.2005.04.034

    authors： Kessler RC,Birnbaum H,Demler O,Falloon IR,Gagnon E,Guyer M,Howes MJ,Kendler KS,Shi L,Walters E,Wu EQ

    更新日期：2005-10-15 00:00:00

  • Prediction of the DST results in depressives by means of urinary-free cortisol excretion, dexamethasone levels, and age.

    abstract：:This study investigates the relationships between cortisol escape from suppression by dexamethasone during a depressive episode, and the baseline activity of the hypothalamic-pituitary-adrenal (HPA) axis, circulating dexamethasone levels, and age. To this end, we measured urinary-free cortisol (UFC) excretion in 24-hr...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/0006-3223(90)90662-l

    authors： Maes M,Jacobs MP,Suy E,Minner B,Raus J

    更新日期：1990-08-15 00:00:00

  • Pseudodementia and ECT.

    abstract：:The author presents six cases of pseudodementia of varying degrees of severity that illustrate the difficulty in making purely clinical diagnoses of pseudodementia and demonstrate the usefulness of ECT in this condition in treatment-resistant patients. In addition, issues of cerebral laterality are raised by one case ...

    journal_title：Biological psychiatry

    pub_type： 杂志文章

    doi：

    authors： Allen RM

    更新日期：1982-12-01 00:00:00