Erythrocyte acetylcholinesterase in psychiatric disorders and controls.

Abstract:

:Acetylcholinesterase (AChE) from erythrocytes was solubilized by Triton X-100. Size and charge heterogeneity of AChE was investigated by polyacrylamide gel electrophoresis (PAGE) and isoelectric focusing (IEF) in polyacrylamide gels in the presence of 0.5% (v/v) Triton X-100. There were no interindividual differences in these parameters in 46 psychiatric patients (schizophrenia, major affective disorder, personality disorder, dependency, dementia) and controls. The specific activity of solubilized AChE did not discriminate between controls and patients or between the diagnostic subgroups.

journal_name

Biol Psychiatry

journal_title

Biological psychiatry

authors

Fritze J,Beckmann H

doi

10.1016/0006-3223(87)90052-7

subject

Has Abstract

pub_date

1987-09-01 00:00:00

pages

1097-106

issue

9

eissn

0006-3223

issn

1873-2402

pii

0006-3223(87)90052-7

journal_volume

22

pub_type

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