Auger processes in the 21st century.

abstract：:The effects of a low dose (0.1-20 mGy) preirradiation with X-rays followed by a higher dose (2 Gy) of the same radiation on the recovery of the genetic damage induced as dominant lethals in mature oocytes (stage 14) of different strains of Drosophila melanogaster were investigated. The response was shown to be depende...

journal_title：International journal of radiation biology

authors： Schäppi-Büchi C

更新日期：1994-04-01 00:00:00

abstract：PURPOSE:A meta-analysis was conducted to obtain a 'quantitative' estimate of the extent of genetic damage in mammalian somatic cells exposed to non-ionizing radiation emitted from extremely low frequency electro-magnetic fields (ELF-EMF) and to compare with that in unexposed control cells. METHODS:The methods used for...

journal_title：International journal of radiation biology

authors： Vijayalaxmi,Prihoda TJ

更新日期：2009-03-01 00:00:00

abstract：:Sister chromatid exchanges (SCEs) were analysed in lymphocytes from 12 control persons and 33 Chernobyl clean-up workers. The group of Chernobyl clean-up workers consisted of civilians who were forced to go to Chernobyl to clean up environmental contamination caused by Chernobyl disaster. On average, they received 0.1...

journal_title：International journal of radiation biology

authors： Lazutka JR,Dedonyte V

更新日期：1995-06-01 00:00:00

abstract：:DNA neutral (pH 9.6) filter elution was used to measure radiation-induced DNA double-strand break (dsb) frequencies in eight human squamous cell carcinoma cell lines with radiosensitivities (D0) ranging from 1.07 to 2.66 Gy and D values ranging from 1.46 to 4.08 Gy. The elution profiles of unirradiated samples from mo...

journal_title：International journal of radiation biology

authors： Schwartz JL,Mustafi R,Beckett MA,Czyzewski EA,Farhangi E,Grdina DJ,Rotmensch J,Weichselbaum RR

更新日期：1991-06-01 00:00:00

abstract：PURPOSE:RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,' is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely active network, a number of new dosimetry methods have recently been proposed or developed. There ...

journal_title：International journal of radiation biology

authors： Ainsbury E,Badie C,Barnard S,Manning G,Moquet J,Abend M,Antunes AC,Barrios L,Bassinet C,Beinke C,Bortolin E,Bossin L,Bricknell C,Brzoska K,Buraczewska I,Castaño CH,Čemusová Z,Christiansson M,Cordero SM,Cosler G,Mo

更新日期：2017-01-01 00:00:00

abstract：:Most estimates of the radiation dose lethal to 50 per cent of a human population are based on historical data taken from well-known experiences reflecting inadequately known physical and biological conditions, or from medical procedures where individual patients received advantages of modern clinical care. It has been...

journal_title：International journal of radiation biology

authors： Morris MD,Jones TD

更新日期：1989-03-01 00:00:00

abstract：:The studies of the late effects of atomic-bomb (A-bomb) radiation on the immune system were started about 20 years after the bombings in 1945. The most remarkable late effects of radiation are the functional and quantitative abnormalities of T and B cells in survivors exposed to high doses (> or = 1.0 Gy). Abnormaliti...

journal_title：International journal of radiation biology

authors： Akiyama M

更新日期：1995-11-01 00:00:00

abstract：:Male SAS/4 mice were injected i.v. with 6.6 kBq 239Pu-citrate. After 1 or 24 h a single i.p. injection of 15 or 30 mumol kg-1 or repeated (three or four) daily injections of 30 mumol kg-1 of tetra-THB-spermine were given, and at 4 or 7 days Pu retention was measured in liver, kidneys and femur. Besides tetra-THB-sperm...

journal_title：International journal of radiation biology

authors： Szot Z,Rochalska M,Chomiczewski K,Chimiak A,Przychodzeń W

更新日期：1989-01-01 00:00:00

abstract：:It is well established from clinical, epidemiological and laboratory studies that specific human germ line mutation can predispose to spontaneously arising cancer. Some of the responsible genes have been characterized at the molecular level and evidence is rapidly accumulating on mechanistic aspects of the problem. A ...

journal_title：International journal of radiation biology

authors： Cox R

更新日期：1994-11-01 00:00:00

abstract：PURPOSE:Since the exact development of posterior subcapsular cataracts (PSCs) is poorly understood, we review various risk factors and propose a two-stage etiology for PSCs. METHODS:The biological mechanisms associated with age-related cataracts (primarily nuclear cataracts, cortical cataracts and PSCs) were reviewed ...

journal_title：International journal of radiation biology

authors： Richardson RB,Ainsbury EA,Prescott CR,Lovicu FJ

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:The deleterious processes triggered by heavy ions on DNA were studied through the determination of the yield of a series of oxidized bases. Emphasis was placed on the estimation of the respective contribution of direct ionization and indirect effects, mostly by comparison with low linear energy transfer (LET) g...

journal_title：International journal of radiation biology

authors： Douki T,Ravanat JL,Pouget JP,Testard I,Cadet J

更新日期：2006-02-01 00:00:00

abstract：:A procedure based on a logistic regression model was used to estimate the dose-modifying effect of chemotherapy on the response of normal tissues to radiation. The magnitude of this modifying effect is usually expressed as a dose-effect factor (DEF). Values > 1.0 indicate an enhancing effect of chemotherapy while valu...

journal_title：International journal of radiation biology

authors： Hao Y,Keane T

更新日期：1994-06-01 00:00:00

abstract：:The induction of chromosome aberrations by X-rays was investigated in synchronized quiescent and proliferating CHO-K1 cells. Kinetics of chromosome lesion repair was studied using the method of fractionated irradiation. In both cell types the time-course of repair during fractionation intervals followed first-order ki...

journal_title：International journal of radiation biology

authors： Volkmer B,Virsik-Peuckert RP

更新日期：1990-12-01 00:00:00

abstract：PURPOSE:A model that identifies radiation-induced genetic instability as the earliest cellular event in the multi-step sequence leading to radiation-induced cancer was previously proposed. In this paper ongoing experiments are discussed which are designed to test this model and its predictions in mouse mammary epitheli...

journal_title：International journal of radiation biology

authors： Ullrich RL,Ponnaiya B

更新日期：1998-12-01 00:00:00

abstract：:Purpose: To summarize existing knowledge and to understand individual response to radiation exposure, the MELODI Association together with CONCERT European Joint Programme has organized a workshop in March 2018 on radiation sensitivity and susceptibility.Methods: The workshop reviewed the current evidence on this matt...

journal_title：International journal of radiation biology

authors： Seibold P,Auvinen A,Averbeck D,Bourguignon M,Hartikainen JM,Hoeschen C,Laurent O,Noël G,Sabatier L,Salomaa S,Blettner M

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Chronic occupational exposure to ionizing radiation (IR) induces a wide spectrum of DNA damages. The aim of this study was to assess the frequencies of micronucleus (MN), sister chromatid exchanges (SCE) and to evaluate their association with XRCC1 399 Arg/Gln and XRCC3 241 Thr/Met polymorphisms in Hospital sta...

journal_title：International journal of radiation biology

authors： Doukali H,Ben Salah G,Ben Rhouma B,Hajjaji M,Jaouadi A,Belguith-Mahfouth N,Masmoudi ML,Ammar-Keskes L,Kamoun H

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:The molecular basis of gene regulation in cells exposed to ionising radiation is not fully understood. Gene regulation occurs at the transcriptional and post-transcriptional levels. Recent studies have suggested that micro-RNA (miRNA) plays a significant role at the post-transcriptional gene regulation. miRNA a...

journal_title：International journal of radiation biology

authors： Chaudhry MA,Kreger B,Omaruddin RA

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:Cells derived from individuals in which the ataxia telangiectasia (ATM) gene is mutated are hypersensitive to ionizing radiation. Whether differences in ATM protein levels exist among human malignant glioma cell lines and whether such differences are correlated with cellular radiosensitivity were determined. M...

journal_title：International journal of radiation biology

authors： Chan DW,Gately DP,Urban S,Galloway AM,Lees-Miller SP,Yen T,Allalunis-Turner J

更新日期：1998-08-01 00:00:00

abstract：PURPOSE:To assess changes in mitochondrial morphology and mitophagy induced by simulated sunlight irradiation (SSI) and how these changes are modulated by mitochondrial activity and energy source. MATERIALS AND METHODS:Human malignant amelanotic melanoma A375 cells were pre-treated with either a mitochondrial activity...

journal_title：International journal of radiation biology

authors： Zanchetta LM,Garcia A,Lyng F,Walsh J,Murphy JE

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Element-specific biokinetic models are used to reconstruct doses to systemic tissues from internal emitters. Typically, a systemic model for a radionuclide explicitly depicts only its dominant repositories. Remaining tissues and fluids are aggregated into a pool called Other tissue in which the radionuclide ...

journal_title：International journal of radiation biology

authors： Leggett RW,Tolmachev SY,Boice JD Jr

更新日期：2018-12-04 00:00:00

abstract：PURPOSE:γ-rays (IR) cause an increase in intracellular calcium [Ca(2+)], alters contractility and triggers apoptosis via the activation of protein kinase C in intestinal guinea pig smooth muscle cells. The present study investigated the role of the mitochondria in these processes and characterized proteins involved in ...

journal_title：International journal of radiation biology

authors： Claro S,Oshiro ME,Mortara RA,Paredes-Gamero EJ,Pereira GJ,Smaili SS,Ferreira AT

更新日期：2014-10-01 00:00:00

abstract：:The effect of heat (43-45 degrees C) on the induction and the repair of DNA double-strand breaks (dsb) was studied in CHO cells after 60 Gy of X-rays using constant-field gel electrophoresis. Heat given prior to irradiation was found not to alter the number of dsb when measured immediately after irradiation. In non-he...

journal_title：International journal of radiation biology

authors： Dahm-Daphi J,Brammer I,Dikomey E

更新日期：1997-08-01 00:00:00

abstract：PURPOSE:To investigate the mechanism of NFkappaB activation by X-rays in normal primary rat astrocytes. MATERIALS AND METHODS:Primary cultures of type I astrocytes generated from the cortex of neonatal rats were exposed to X-rays with and without various kinase inhibitors and a protease inhibitor. The nuclear or cytop...

journal_title：International journal of radiation biology

authors： Raju U,Gumin GJ,Noel F,Tofilon PJ

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:The linear nonthreshold (LNT) model has been used in radiation protection for over 40 years and has been hotly debated. It relies heavily on human epidemiology, with support from radiobiology. The scientific underpinnings include NCRP Report No. 136 ('Evaluation of the Linear-Nonthreshold Dose-Response Model fo...

journal_title：International journal of radiation biology

authors： Boice JD Jr

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To carry out a comparative study on potential cytogenetic fingerprints for radiation LET in human metaphase lymphocytes. MATERIALS AND METHOD:Human lymphocytes were irradiated in vitro with 3.0 Gy 60Co gamma-rays, 0.9 Gy 3H beta-rays or 0.2 Gy 2.7 Mev neutrons. Detailed chromosome aberrations were analysed by ...

journal_title：International journal of radiation biology

authors： Deng W,Morrison DP,Gale KL,Lucas JN

更新日期：2000-12-01 00:00:00

abstract：PURPOSE:To determine the efficacy of a caffeine derivative 1-methylxanthine (1-MTX) in increasing radiosensitivity of cancer cells and elucidate the underlying mechanisms in vitro. MATERIALS AND METHODS:RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53) were incubated with 3 mM 1-MTX for 30 min,...

journal_title：International journal of radiation biology

authors： Youn H,Hee Kook Y,Oh ET,Jeong SY,Kim C,Kyung Choi E,Uk Lim B,Park HJ

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:Radiotherapy is an important treatment option for brain tumors, but the unavoidable irradiation of normal brain tissue can lead to delayed cognitive impairment. The mechanisms involved are still not well explained and, therefore, new tools to investigate the processes leading to the delayed symptoms of brain ir...

journal_title：International journal of radiation biology

authors： Parente A,Maciel ES,J O Dierckx RA,Langendijk JA,de Vries EFJ,Doorduin J

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:One of the most important issues regarding radiofrequency electromagnetic fields (RF-EMF) is their effect on genetic material. Therefore, we investigated the cytogenotoxic effects of 900 MHz radiofrequency electromagnetic fields (RF-EMF) and the effect of a recovery period after exposure to RF-EMF on bone marro...

journal_title：International journal of radiation biology

authors： Atlı Şekeroğlu Z,Akar A,Şekeroğlu V

更新日期：2013-11-01 00:00:00

abstract：:The mechanisms of radiation damage production are used to examine the following premises: (1) the number of DNA double-strand breaks per unit dose increases with dose; (2) cell type to cell type variations in yield of DNA dsb per dose occur. Two stages of damage production are identified as possible sources of damage ...

journal_title：International journal of radiation biology

authors： Ward JF

更新日期：1990-06-01 00:00:00

abstract：PURPOSE:To investigate and compare the propensity of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines (LCL) obtained from unaffected healthy individuals and ataxia telangectasia (A-T) patients to undergo apoptosis after X-ray exposure. MATERIAL AND METHODS:The LCL were exposed to 1-4 Gy X-rays at a dose-...

journal_title：International journal of radiation biology

authors： Meijer AE,Zhivotovsky B,Lewensohn R

更新日期：1999-06-01 00:00:00