Nevirapine toxicity in non-HIV cancer patients.

abstract：BACKGROUND:Taxanes cause hypersensitivity reactions, averted by premedication with H1 blockers and high glucocorticoid (GC) doses. Prolonged weekly taxane administration may lead to GC toxicity. PURPOSE:To determine whether patients not hypersensitive to initial paclitaxel (PTX) infusion after high-dose GC premedicati...

journal_title：Chemotherapy

authors： Braverman AS,Rao S,Salvatti ME,Adamson B,McManus M,Pierre S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate the impact of different temperatures (22, 35 and 37 degrees C) on the postantifungal effect (PAFE) and the effect of sub-MIC concentrations (1/4 x MIC) on Candida albicans and Candida glabrata in PAFE stage (PAFSE). METHODS:This stage was induced by a 1.5-hour ...

journal_title：Chemotherapy

authors： García MT,Llorente MT,Mínguez F,Prieto J

更新日期：2000-07-01 00:00:00

abstract：:The in vitro activities of the newer agents Deptomycin, Difloxacin, A-56620 and Ciprofloxacin were compared with those of vancomycin, rifampin and gentamicin against methicillin-susceptible and -resistant Staphylococcus aureus and coagulase-negative staphylococci. All isolates were susceptible to vancomycin, rifampin,...

journal_title：Chemotherapy

authors： Chandrasekar PH,Sluchak JA

更新日期：1989-01-01 00:00:00

abstract：:Resistant variants of three clinical Pseudomonas aeruginosa isolates were obtained in the presence of aztreonam. The variants exhibited a four- to eightfold increase in the minimal inhibitory concentrations to beta-lactam antibiotics (except imipenem) to quinolones, such as norfloxacin and fleroxacin, chloramphenicol ...

journal_title：Chemotherapy

authors： Leying HJ,Büscher KH,Cullmann W,Then RL

更新日期：1992-01-01 00:00:00

abstract：:The choice of antimicrobial therapy for the treatment of bacteremia is often empirical and based on the knowledge of susceptibility profiles of the most common bacteria. We analyzed blood culture isolates from a teaching hospital for 13 years prospectively. This study examined the susceptibility profiles of 6,616 gram...

journal_title：Chemotherapy

authors： Ling TK,Liu EY,Cheng AF

更新日期：2001-01-01 00:00:00

abstract：:An in vitro infection model was created using a suspension of macrophages, polymorphonuclear leukocytes, lymphocytes, fibroblasts, and human serum to which pathogen and antibiotic were added. Separate intracellular and extracellular antibiotic concentrations and activity against Staphylococcus aureus and Legionella pn...

journal_title：Chemotherapy

authors： Scaglione F,Demartini G,Dugnani S,Fraschini F

更新日期：1993-11-01 00:00:00

abstract：:The efficacy of ofloxacin for the treatment of lower respiratory tract infection was evaluated in aged patients with chronic lung disease. Results are the following: improvement of leukocytosis and arterial oxygen tension was observed; peripheral blood cell analysis showed a decrease in natural killer cell counts and ...

journal_title：Chemotherapy

authors： Yamaoka M,Fukuchi Y,Yokouchi M,Teramoto N,Nagase T,Ishida K,Ohtomo E,Orimo H

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Brucellosis is one of the important health problems for both humans and animals in Turkey since agriculture and stock raising appears to be the most important means of subsistence. Investigations on the pathogenesis of brucellosis reveal that the etiologic agent can survive in phagocytic cells, and cell-medi...

journal_title：Chemotherapy

authors： Dizer U,Hayat L,Beker CM,Görenek L,Ozgüven V,Pahsa A

更新日期：2005-03-01 00:00:00

abstract：:Malignant external otitis is a serious infection most frequently caused by Pseudomonas aeruginosa. Because of its antipseudomonal activity and good tissue penetration, ciprofloxacin is an antibiotic which should, in theory, be effective in the treatment of this type of infection. Publications on the use of ciprofloxac...

journal_title：Chemotherapy

authors： Gehanno P

更新日期：1994-01-01 00:00:00

abstract：:20 patients with serious infections were treated with cefazolin and tobramycin for 9--64 days. Minimal inhibitory concentration (MIC) values and minimal bactericidal concentration (MBC) values were determined for each of the 112 clinical bacterial isolates. The median cefazolin MIC/MBC was 1.56/12.5 micrograms/ml, and...

journal_title：Chemotherapy

authors： Franson TR,Edwards LD,Collins RF,Root TE

更新日期：1980-01-01 00:00:00

abstract：:Susceptibility of 983 isolates of Staphyloccus aureus to tetracycline, doxycycline and minocycline was determined in vitro. Minocycline was shown to be more active than doxycycline, which in turn was shown to be slightly more active than tetracycline. 77% of the isolates which were resistant to tetracycline were also ...

journal_title：Chemotherapy

authors： Lewis SA,Altemeier WA

更新日期：1976-01-01 00:00:00

abstract：:Therapeutic effectiveness of pretazettine (PTZ) has been demonstrated in the intraperitoneally (i.p.) implanted Lewis lung carcinoma (LLC) in both syngeneic and allogeneic mice. The i.p. implanted LLC has been found to be sensitive to most standard drugs tested such as cyclophosphamide (CY), actinomycin D, 5-fluoroura...

journal_title：Chemotherapy

authors： Furusawa E,Furusawa E,Sokugawa L

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:We investigated the presence of Helicobacter pylori in laryngeal cancer specimens to reveal whether or not this is a risk factor in the development of squamous cell carcinoma of the larynx. METHODS:Sixty-nine total laryngectomy specimens with the pathologic diagnosis of squamous cell carcinoma and 30 larynge...

journal_title：Chemotherapy

authors： Kizilay A,Saydam L,Aydin A,Kalcioglu MT,Ozturan O,Aydin NE

更新日期：2006-01-01 00:00:00

abstract：:We established a method for determining the KD value as a measure of the bilirubin-displacing effect for drugs by using bilirubin oxidase, which is produced by Myrothecium verrucaria MT-1. This method makes it possible to conduct measurements of many beta-lactam antibiotics, including those which could not be determin...

journal_title：Chemotherapy

authors： Matsuura A,Nagayama T,Kitagawa T

更新日期：1988-01-01 00:00:00

abstract：:New fluoroquinolones, as exemplified by levofloxacin, possess broad spectrum activity against many common pathogens, including the majority responsible for respiratory tract infections (RTIs), atypical pathogens and those resistant to other therapeutic regimens. Following administration, levofloxacin attains high intr...

journal_title：Chemotherapy

authors： Graninger W,Zeitlinger M

更新日期：2004-01-01 00:00:00

abstract：:The introduction of highly active antiretroviral therapy (HAART) has significantly modified the course of human immunodeficiency virus (HIV) disease, with longer survival and improved quality of life of HIV-infected subjects. However, HAART regimens, especially those including protease inhibitors, have been shown to c...

journal_title：Chemotherapy

authors： Barbaro G,Barbarini G

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the therapeutic adult antibiotics prescribed by dental practitioners working in the Jordan University Hospital. METHODS:Adult dental prescriptions for therapeutic antibiotics issued between 1 January 2003 and 31 May 2004 by dental specialists working in the Jordan Unive...

journal_title：Chemotherapy

authors： Dar-Odeh NS,Abu-Hammad OA,Khraisat AS,El Maaytah MA,Shehabi A

更新日期：2008-01-01 00:00:00

abstract：:A unique process has been developed to convert bituminous coal by controlled wet oxidation followed by base treatment to a water-soluble humate called oxihumate. Oxihumate inhibited HIV-1 infection of MT-2 cells with an IC(50) of 12.5 microg/ml. Treatment of free and cell-attached HIV with oxihumate irreversibly reduc...

journal_title：Chemotherapy

authors： van Rensburg CE,Dekker J,Weis R,Smith TL,Janse van Rensburg E,Schneider J

更新日期：2002-07-01 00:00:00

abstract：:Therapy of listeriosis with ampicillin was examined in two murine models with compromised defense mechanisms. In mice treated with dextran sulfate paralysing the function of the macrophage system, ampicillin was less able to reduce death rates as well as bacterial counts in the spleens than after infection of normal m...

journal_title：Chemotherapy

authors： Hof H,Emmerling P,Seeliger HP

更新日期：1981-01-01 00:00:00

abstract：:Reference is made to the results obtained in 24 children, from 11 months to 12 years, affected with acute pneumopathies and treated with fosfomycin with a dosage of 200 mg/kg/day. In all cases a clinical, radiological, biological and bacteriological study was carried out. At the same time, levels of fosfomycin in plas...

journal_title：Chemotherapy

authors： Llorens J,Ley G,Forés A,Olay T

更新日期：1977-01-01 00:00:00

abstract：:Two gonococcal strains with differing susceptibility to cefotiam and ceftizoxime, as expressed by the minimum inhibitory concentration (MIC), are exposed to continuously changing concentrations of these antibiotics as they are found in plasma and skin cantharidal blister fluid (CBF) after a single intramuscular applic...

journal_title：Chemotherapy

authors： Korting HC,Niederauer H,Ollert M

更新日期：1986-01-01 00:00:00

abstract：:Community-acquired pneumonia (CAP) is a common illness that creates significant burdens upon the healthcare system. Improving the quality of medical care for patients with this illness requires an evidence-based and cost-efficient treatment approach. The first step in this approach is to make an accurate diagnosis, wh...

journal_title：Chemotherapy

authors： Fine MJ

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:This study was conducted to determine the antimicrobial susceptibility patterns among common pathogens in the intensive care unit (ICU) of a university hospital in Iran between 2006 and 2009. METHODS:The isolates cultured in appropriate media and antimicrobial susceptibility were determined by disk diffusio...

journal_title：Chemotherapy

authors： Mohammadtaheri Z,Pourpaki M,Mohammadi F,Namdar R,Masjedi MR

更新日期：2010-01-01 00:00:00

abstract：:Neutropenia induced by intensive chemotherapy and allogeneic bone marrow transplantation are increasingly commonly complicated by fungal infections; thus prophylaxis may be justified. The authors surveyed the literature and culled their experience - few randomized trials have been done and definitions have often been ...

journal_title：Chemotherapy

authors： Denning DW,Donnelly JP,Hellreigel KP,Ito J,Martino P,van't Wout JW

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Combination antimicrobial therapy is often necessary to eradicate infections caused by gram-negative bacteria. METHODS:To evaluate the potential benefit of aztreonam and fluoroquinolone combination therapy, the activity of aztreonam in combination with ciprofloxacin, gatifloxacin, levofloxacin and moxifloxa...

journal_title：Chemotherapy

authors： Critchley IA,Sahm DF,Kelly LJ,Karlowsky JA

更新日期：2003-05-01 00:00:00

abstract：:The intraphagocytic killing of Escherichia coli, Serratia marcescens, Pseudomonas aeruginosa, and Salmonella typhi by ciprofloxacin (0.1, 1 and 5 microg/ml) within human neutrophils with intact and impaired (by phenylbutazone treatment) O2-dependent killing mechanisms was studied and compared with the extracellular ki...

journal_title：Chemotherapy

authors： Cantón E,Peman J,Cabrera E,Velert M,Orero A,Pastor A,Gobernado M

更新日期：1999-07-01 00:00:00

abstract：:Uptake of the bifunctional alkylating agent, PTT.119, p-F-Phe-m-bis-(2-chloroethyl)amino-L-Phe-Met-ethoxy-HCl, by the MJY-alpha mammary tumor and B16 melanoma cell lines occurred via two natural pathways for amino acid transport. The primary route of PTT.119 entry was the classical L System, whereas, the ASC System ca...

journal_title：Chemotherapy

authors： Yagi MJ,Scanlon KJ,Chin SE,Bekesi JG

更新日期：1988-01-01 00:00:00

abstract：:Minimal bactericidal concentrations of trimethoprim, nalidixic acid, and nitrofurantoin revealed effective intraphagolysosomal bactericidal activity against several assay strains of Serratia marcescens as determined with phenylbutazone-treated (2 mg/ml) fresh defibrinated human blood (55 vol%), following killing of ex...

journal_title：Chemotherapy

authors： Traub WH

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND/AIMS:Species-level identification of nontuberculous mycobacteria (NTM) is important in making decisions about the necessity and choice of antimicrobial treatment. The reason is predictable clinical significance and the susceptibility profile of specific NTM species. Matrix-assisted laser desorption/ionizatio...

journal_title：Chemotherapy

authors： Mareković I,Bošnjak Z,Jakopović M,Boras Z,Janković M,Popović-Grle S

更新日期：2016-01-01 00:00:00

abstract：:Combination antiretroviral (ARV) treatment is a potent and effective therapy for human immunodeficiency virus infection. Unfortunately, ARV drugs frequently interact among themselves, as well as with other anti-infectives. These interactions determine positive or negative consequences resulting in recommendations to a...

journal_title：Chemotherapy

authors： Pontali E

更新日期：2007-01-01 00:00:00