Exacerbation of autoimmune thyroiditis by a single low dose of whole-body irradiation in non-obese diabetic-H2h4 mice.

abstract：PURPOSE:The effect of extremely low frequency electromagnetic fields (ELF-EMF) on bacteria has attracted attention due to its potential for beneficial uses. This research aimed to determine the effect of ELF-EMF on bacterial membrane namely the membrane potential, surface potential, hydrophobicity, respiratory activity...

journal_title：International journal of radiation biology

authors： Oncul S,Cuce EM,Aksu B,Inhan Garip A

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:We introduce and evaluate a high throughput biodosimetry test system (REDI-Dx) suitable for testing of thousands of potential radiation victims following a mass scale nuclear event caused by detonation of a nuclear device or a nuclear accident, as part of an overall strategy for effective medical management of ...

journal_title：International journal of radiation biology

authors： Jacobs AR,Guyon T,Headley V,Nair M,Ricketts W,Gray G,Wong JYC,Chao N,Terbrueggen R

更新日期：2020-01-01 00:00:00

abstract：:DNA double-strand break (dsb) induction in diploid yeast was measured by neutral sucrose sedimentation after exposure to very heavy ions with values of linear energy transfer (LET) ranging from about 300 to 11500 ke V/microns. Linear fluence dependencies were found in all cases from which dsb production cross-sections...

journal_title：International journal of radiation biology

authors： Akpa TC,Weber KJ,Schneider E,Kiefer J,Frankenberg-Schwager M,Harbich R,Frankenberg D

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:Ukrain, an alkaloid thiophosphoric acid derivative of Chelidonium majus L., has demonstrated a promising impact on chemotherapy in a variety of malignancies. The effects of the drug on cell survival, alteration of the cell cycle and induction of apoptosis were examined without and in combination with ionizing r...

journal_title：International journal of radiation biology

authors： Cordes N,Plasswilm L,Bamberg M,Rodemann HP

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:5-Formyluracil (5-foU) is a major derivative of thymine produced in DNA by ionizing radiation and various chemical oxidants. It has been previously shown that 5-foU in template DNA directs misincorporation of nucleotides by DNA polymerases during in vitro DNA synthesis. The present experiments were designed to ...

journal_title：International journal of radiation biology

authors： Miyabe I,Zhang QM,Sugiyama H,Kino K,Yonei S

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:Hypoxic cells in tumours are resistant to 5-fluorouracil (5-FU). This in vivo study investigated the ability of hypoxia to regulate the gene expression of thymidylate synthase (TS), the target enzyme of 5-FU. MATERIALS AND METHODS:C3H mammary carcinomas, grown in the feet of female CDF1 mice, were used for all...

journal_title：International journal of radiation biology

authors： Ehrnrooth E,von der Maase H,Sørensen BS,Poulsen JH,Horsman MR

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:In this study we addressed the question whether radiation-induced adverse effects on T cell activation are associated with alterations of T cell checkpoint receptors. MATERIALS AND METHODS:Expression levels of checkpoint receptors on T cell subpopulations were analyzed at multiple post-radiation time points ra...

journal_title：International journal of radiation biology

authors： Li D,Chen R,Wang YW,Fornace AJ Jr,Li HH

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:Since previous research found an increase in the rate of aneuploidies in human lymphocytes exposed to radiofrequencies, it seems important to perform further studies. The objective of this study was then to investigate whether the exposure to RF (radiofrequency) radiation similar to that emitted by mobile phone...

journal_title：International journal of radiation biology

authors： Bourthoumieu S,Terro F,Leveque P,Collin A,Joubert V,Yardin C

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:The detection of long-term persistent chromosome aberrations in circulating haemopoietic stem cells after accidental radiation exposure. MATERIAL AND METHODS:Peripheral blood samples from highly exposed persons were collected 7-25 years after the radiation accidents in Moscow (1971), Kazan (1975) and Chernobyl...

journal_title：International journal of radiation biology

authors： Kreja L,Greulich KM,Fliedner TM,Heinze B

更新日期：1999-10-01 00:00:00

abstract：PURPOSE:This review examines the evidence for the hypothesis that epigenetics are involved in the initiation and perpetuation of radiation-induced genomic instability (RIGI). CONCLUSION:In addition to the extensively studied targeted effects of radiation, it is now apparent that non-targeted delayed effects such as RI...

journal_title：International journal of radiation biology

authors： Aypar U,Morgan WF,Baulch JE

更新日期：2011-02-01 00:00:00

abstract：:The radiation response of 15 mammalian cell lines comprising 11 human tumour, two human fibroblast and two murine lymphoma cell lines, has been analysed using the linear-quadratic equation. As well as using conventional analysis of acute dose-survival curves to derive values for alpha and beta (termed alpha ac and bet...

journal_title：International journal of radiation biology

authors： Peacock JH,Eady JJ,Edwards SM,McMillan TJ,Steel GG

更新日期：1992-04-01 00:00:00

abstract：PURPOSE:The assessment of biological effects caused by radiation exposure has been currently carried out with the linear-quadratic (LQ) model as an extension of the linear non-threshold (LNT) model. In this study, we suggest a new mathematical model named as SeaSaw (SS) model, which describes proliferation and cell dea...

journal_title：International journal of radiation biology

authors： Bando M,Tsunoyama Y,Suzuki K,Toki H

更新日期：2020-12-15 00:00:00

abstract：:We used the 'comet assay' to compare the amount of radiation-induced DNA damage in three tumour cell lines (MeWo, PECA 4451 and PECA 4197) and the extent of DNA repair in two of these lines (MeWo and PECA 4197). Tumour cells were irradiated with X-rays (0.1-10 Gy), embedded in agarose on slides, lysed with sodium dode...

journal_title：International journal of radiation biology

authors： Müller WU,Bauch T,Streffer C,Niedereichholz F,Böcker W

更新日期：1994-03-01 00:00:00

abstract：:PACE (programmable, autonomously controlled electrodes) pulsed field gel electrophoresis technology was used to develop a DNA double-strand break assay that simultaneously combined (1) resolution across a broad range of DNA sizes, (2) high sensitivity (in terms of detecting dsb at low doses) and (3) speed. A 48 h PACE...

journal_title：International journal of radiation biology

authors： Elia MC,Nichols WW

更新日期：1993-01-01 00:00:00

abstract：:One of the major goals of cancer research is to identify and understand the causes of cellular proliferation. The role of cell death, or lack thereof, in carcinogenesis, tumour growth, metastatic spread and response to treatment has been largely overlooked even though the morphology of apoptosis (programmed cell death...

journal_title：International journal of radiation biology

authors： Blank KR,Rudoltz MS,Kao GD,Muschel RJ,McKenna WG

更新日期：1997-05-01 00:00:00

abstract：:Human ovarian carcinoma parental and cisplatin-resistant cells were evaluated for their radiation sensitivity to high and low dose-rate irradiation and for the effectiveness of cisplatin in radiosensitization. The cisplatin resistant variant A2780cp showed increased radiation resistance for both low dose-rate (LDRI) a...

journal_title：International journal of radiation biology

authors： Raaphorst GP,Wang G,Stewart D,Ng CE

更新日期：1996-05-01 00:00:00

abstract：PURPOSE:Many strategies have been investigated to exclude the several side-effects of pharmacological or invasive treatments. Non-invasive pulsed magnetic field (PMF) treatment with no toxicity or side-effects can be an alternative to pharmacologic treatments. The purpose of this study was, therefore, to investigate th...

journal_title：International journal of radiation biology

authors： Mert T,Ocal I,Cinar E,Yalcin MS,Gunay I

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To develop a procedure, using the inverse polymerase chain reaction, to detect and sequence ionizing radiation-induced DNA rearrangements without prior phenotypic selection of mutant cells. METHOD:Normal human fibroblast cells (IMR-90) were given 30Gy of gamma-irradiation and then incubated at 37 degrees C for...

journal_title：International journal of radiation biology

authors： Forrester HB,Radford IR

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:The low dose (<1 Gy) survival curve of mammalian cells is characterized by a region of hypersensitivity (HRS) followed by increased resistance (IRR). Above 1 Gy, the survival response can be described with a smooth downward-bending curve. Indirect evidence has indicated that the IRR response might reflect an in...

journal_title：International journal of radiation biology

authors： Marples B,Joiner MC

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:To investigate alternative scenarios for the dose-dependent emission of bystander signals by irradiated cells in medium transfer experiments. METHODS:Energy deposition patterns to hypothetical intracellular targets whose hit by radiation initiates the emission of bystander signals have been simulated by Monte ...

journal_title：International journal of radiation biology

authors： Kundrát P,Friedland W

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To calculate the depth distribution of radioactive decays in bone by fitting a calculated alpha-particle energy spectrum to a measured spectrum. The dose to bone surface cells is then calculated from the depth distribution. MATERIALS AND METHODS:The spectra are calculated using Monte Carlo methods and a numeri...

journal_title：International journal of radiation biology

authors： Charlton DE,Salmon PL,Utteridge TD

更新日期：1998-01-01 00:00:00

abstract：:Photoirradiation of aqueous solutions of DNA in the presence of Al- or Zn-tetrasulphonated phthalocyanines (AIPcS4 and ZnPcS4) causes formation of strand breaks and liberation of nucleobases. The effect of added D2O, which enhances singlet oxygen (1O2) lifetime, radical scavengers including alcohols and the spin-trap ...

journal_title：International journal of radiation biology

authors： Gantchev TG,Gowans BJ,Hunting DJ,Wagner JR,van Lier JE

更新日期：1994-12-01 00:00:00

abstract：PURPOSE:To honour perhaps the most influential man in the radiation sciences, Henry S. Kaplan, by reviewing the field of tumour hypoxia, one of his many interests. RESULTS:It was postulated over 50 years ago by Thomlinson and Gray that human solid tumours would contain hypoxic cells and that they would exert a negativ...

journal_title：International journal of radiation biology

authors： Brown M

更新日期：2010-11-01 00:00:00

abstract：:We studied the extent of split-dose recovery in seven non-transformed human fibroblast cell lines of different intrinsic radiosensitivity (HF19, 1BR3, 149BR, 84BR, GM739, 180BR and AT2EM). Experiments were performed on both growing and plateau-phase cells. The seven cell lines displayed a wide range of intrinsic radio...

journal_title：International journal of radiation biology

authors： Alsbeih MG,Fertil B,Arlett CF,Malaise EP

更新日期：1996-02-01 00:00:00

abstract：PURPOSE:Zearalenone is a potent estrogenic metabolite produced by some Fusarium and Gibberella species. Therefore, the aim of this study was to determine the accumulation of Technetium-[99m]-labeled zearalenone in mice organs as well as to study the protective effect of Lactobacillus plantarum. MATERIALS AND METHODS:T...

journal_title：International journal of radiation biology

authors： Sanad MH,Fouzy ASM,Sobhy HM,Hathout AS,Hussain OA

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:The nature of the transferrable factor which goes from irradiated objects to bystander objects remains undefined. Most agree that a chemical entity is the likely 'factor' although some authors have produced in vitro evidence for the involvement of a physical component or a very potent volatile capable of travel...

journal_title：International journal of radiation biology

authors： Mothersill C,Smith RW,Fazzari J,McNeill F,Prestwich W,Seymour CB

更新日期：2012-08-01 00:00:00

abstract：:Base damages, sugar damages, and single-strand breaks produced by free radicals are the preponderant lesions produced in DNA by ionizing radiation. These lesions have been individually introduced into substrate, template, and biologically active DNA molecules and enzymatic processing and biological consequences determ...

journal_title：International journal of radiation biology

authors： Wallace SS

更新日期：1994-11-01 00:00:00

abstract：:Purpose: Radiotherapy prescription dose and dose fractionation protocols vary little between individual patients having the same tumor grade and stage. To personalize radiotherapy a predictive model is needed to simulate radiation response. Previous modeling attempts with multiple variables and parameters have been sh...

journal_title：International journal of radiation biology

authors： Sunassee ED,Tan D,Ji N,Brady R,Moros EG,Caudell JJ,Yartsev S,Enderling H

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:As the most recent epidemiological studies provide no definite conclusions about the effects of 50/60 Hz magnetic fields (MFs) on the incidence of leukaemia in humans, animal models in a well-controlled environment are useful for evaluating the possibility of an association between MFs and leukaemia. The presen...

journal_title：International journal of radiation biology

authors： Devevey L,Patinot C,Debray M,Thierry D,Brugere H,Lambrozo J,Guillosson JJ,Nafziger J

更新日期：2000-06-01 00:00:00

abstract：:Purpose: To study the response of neuronal-like cells to an applied static or low-frequency magnetic field. Materials and methods: Fourier Transform Infrared (FTIR) Spectroscopy was used to investigate the overall behavior of SH-SY5Y neuronal-like cells exposed to a static or 50 Hz magnetic fields at intensities up to...

journal_title：International journal of radiation biology

authors： Calabrò E,Magazù S

更新日期：2019-06-01 00:00:00