Hydrogen sulfide: a novel mediator of leukocyte activation.

abstract：:Naloxone at concentrations 10(-6) M to 10(-10) M modulated endogenous NK-activity in 11 of 14 samples of human peripheral blood lymphocytes after 18-hour incubation. The dose response usually showed two peaks, which varied with the donor. Enhancement was obtained in 6, suppression in 4, and both effects (depending on ...

journal_title：Immunopharmacology and immunotoxicology

authors： Martin-Kleiner I,Gabrilovac J

更新日期：1993-03-01 00:00:00

abstract：:The effects of anti-thyroid drug, methimazole (MMI), on haematopoiesis in inbred C57BL/6 mice were studied. The in vitro proliferative response of bone marrow (BM) cells to interleukin-3 (IL-3) was significantly increased when mice were provided with 0.1% MMI in water (w/v) ad librium for 4 to 6 weeks. Using soft agar...

journal_title：Immunopharmacology and immunotoxicology

authors： Mak NK,Lai WH,Liu WK,Leung KN,Fung MC

更新日期：1995-11-01 00:00:00

abstract：:We investigated immunomodulatory activity of autologous tumor cell vaccine from oral cancer patients ex vivo by lymphoproliferation assay and two color flow cytometry. Vaccine treatment lead to 10-fold higher proliferation of lymphocytes compared with the untreated controls. A significant increase in CD69(+) and HLA-D...

journal_title：Immunopharmacology and immunotoxicology

authors： Agarwal A,Mohanti BK,Das SN

更新日期：2007-01-01 00:00:00

abstract：:Objective: Acne is a chronic skin disease that involves four key pathogenic factors: excess sebum production, ductal epidermal hyperproliferation, Propionibacterium acnes (P. acnes) colonization, and skin inflammation. Mangostins are well-known for their anti-bacterial and anti-inflammatory effects, suggesting that ma...

journal_title：Immunopharmacology and immunotoxicology

authors： Xu N,Deng W,He G,Gan X,Gao S,Chen Y,Gao Y,Xu K,Qi J,Lin H,Shen L,Li X,Hu Z

更新日期：2018-10-01 00:00:00

abstract：:During the last few years, several observations outline that the impaired T lymphocyte proliferative capacity in the elderly is due to a reduced interleukin 2 (IL-2) release. To further investigate the activation process during lectin stimulation, aged peripheral blood mononuclear cells (PBMC) were stimulated with phy...

journal_title：Immunopharmacology and immunotoxicology

authors： Antonaci S,Tortorella C,Polignano A,Ottolenghi A,Jirillo E,Bonomo L

更新日期：1991-01-01 00:00:00

abstract：:Protective effect of a Japanese traditional herbal medicine, Juzen-taiho-to (TJ-48), which was recently reported to augment host-mediated antifungal actions, in Candida albicans-infected mice was further studied. TJ-48, given orally once daily for 5 consecutive days in a dose of 2 g/kg after intravenous infection of C...

journal_title：Immunopharmacology and immunotoxicology

authors： Akagawa G,Abe S,Tansho S,Uchida K,Yamaguchi H

更新日期：1996-02-01 00:00:00

abstract：:PMA (10, 20 ng/ml) and doxorubicin (5-20 ng/ml) decreased the viability and MTT-activity of NALM-1 pre-B leukemic cells (3 days' treatment). Further, CD10 was downregulated, suggesting that PMA and doxorubicin induced differentiation of NALM-1 cells. However, PMA did not alter expression of B cell markers CD20 and of ...

journal_title：Immunopharmacology and immunotoxicology

authors： Martin-Kleiner I,Svoboda-Beusan I,Gabrilovac J

更新日期：2006-01-01 00:00:00

abstract：:Chronic administration of oxytetracycline (OXT) (incorporated at a level of 0.05 g per kg of feed for 50 days) to pigeons, significantly decreased total leukocyte and lymphocyte counts, increased heterophil:lymphocyte ratio and lysosomal enzyme activity, and decreased reticuloendothelial system function compared with ...

journal_title：Immunopharmacology and immunotoxicology

authors： Al-Ankari AS

更新日期：2005-01-01 00:00:00

abstract：CONTEXT:Disease Modifying Anti-Rheumatic Drugs (DMARDs) are aimed to interfere with rheumatoid arthritis (RA) progression and reduce the joint damage; however, not all patients respond alike. Killer-cell immunoglobulin-like receptors (KIR) and their ligands, human leucocyte antigen class I (HLA-I), have been associated...

journal_title：Immunopharmacology and immunotoxicology

authors： Velarde-de la Cruz EE,Sánchez-Hernández PE,Muñoz-Valle JF,Palafox-Sánchez CA,Ramírez-de Los Santos S,Graciano-Machuca O,García-Iglesias T,Montoya-Buelna M,Ramírez-Dueñas MG

更新日期：2016-08-01 00:00:00

abstract：UNLABELLED:The angiotensin (Ang)-converting enzyme (ACE) insertion/deletion (I/D) polymorphism determines Ang II levels, but its relationship with lupus nephritis (LN) in different populations is controversial. OBJECTIVE:To describe the allelic and genotypic distribution of the I/D polymorphism in Mexican mestizos wit...

journal_title：Immunopharmacology and immunotoxicology

authors： Topete-Reyes JF,Soto-Vargas J,Morán-Moguel MC,Dávalos-Rodríguez IP,Chávez-González EL,García-de la Torre I,Parra-Michel R,Medina-Pérez M,Jalomo-Martínez B,Salazar-Páramo M

更新日期：2013-02-01 00:00:00

abstract：:Chief part of hemopoietic stromal cells in mediating hemopoiesis-stimulating effects of adamantylamide dipeptide (AdDP), a synthetic immunomodulatory compound, has been determined in a series of combined in vivo/in vitro studies. Indirect stimulatory effect of AdDP on proliferation of hemopoietic progenitor cells for ...

journal_title：Immunopharmacology and immunotoxicology

authors： Vacek A,Hofer M,Weiterová L,Hoferová Z,Pipalová I,Masek K

更新日期：2001-11-01 00:00:00

abstract：:The immunological status of lead acid battery workers with blood lead levels and urinary delta-aminolevulinic acid (ALA-U) concentrations ranging from safe to toxic levels has been examined and compared with those of non-exposed, age and sex matched controls. No differences in the serum concentrations of IgG, IgA and ...

journal_title：Immunopharmacology and immunotoxicology

authors： Queiroz ML,Perlingeiro RC,Bincoletto C,Almeida M,Cardoso MP,Dantas DC

更新日期：1994-02-01 00:00:00

abstract：:Two dideoxynucleosides, 2',3'-dideoxy-beta-L-cytidine and 2',3'-dideoxy-beta-L-5-flurocytidine, containing unnatural L-configuration in their sugar moieties, were synthesized and assayed for antiviral activities. Both compounds were shown to possess potent anti-human immunodeficiency virus type 1 and antihepatitis B v...

journal_title：Immunopharmacology and immunotoxicology

authors： Gagnon L,Nordstrom PA,Duchaine J,Jutras D,Hamel M,Barbeau D,Hooker E,Ashman C,Cammack N,Tse A

更新日期：1995-02-01 00:00:00

abstract：:We investigated the effect of Z-100, a polysaccharide-rich extract from Mycobacterium tuberculosis strain Aoyama B, on the protection of immunocompromised mice against infection with Pseudomonas aeruginosa. Mice were given cyclophosphamide and then treated with varying doses of Z-100 for 5 days or left untreated. One ...

journal_title：Immunopharmacology and immunotoxicology

authors： Kawamura I,Mitsuyama M,Nomoto K

更新日期：1990-01-01 00:00:00

abstract：:Plants have been shown to possess a number of beneficial anticancer and immunomodulatory properties. In this study the possible in vitro antitumor activity and immunomodulatory effects of five species of Euphorbia, an important genus of Euphorbiaceae, including E. petiolata, E. hebecarpa, E. osyridea, E. microciadia, ...

journal_title：Immunopharmacology and immunotoxicology

authors： Amirghofran Z,Malek-hosseini S,Gholmoghaddam H,Kalalinia F

更新日期：2011-03-01 00:00:00

abstract：:A substantial body of research exists to support the production of growth hormone by cells of the immune system. However, the function and mechanism of action of lymphocyte-derived growth hormone remain largely unelucidated. Since, it has been found that exogenous growth hormone (GH) primes neutrophils for the product...

journal_title：Immunopharmacology and immunotoxicology

authors： Arnold RE,Weigent DA

更新日期：2003-05-01 00:00:00

abstract：:Identifying the regulatory T cells (Tregs) and Th17 cells led to breaking the dichotomy of Th1/Th2 cells axis in immune responses involved in several autoimmune diseases. It is now well known that Tregs and Th17 cells are main orchestra leaders in pathogenesis symphony of autoimmunity. While Tregs are protective cells...

journal_title：Immunopharmacology and immunotoxicology

authors： Jadidi-Niaragh F,Mirshafiey A

更新日期：2012-10-01 00:00:00

abstract：:We have developed an in vitro system to model the interactions of drugs used to treat transplant rejection. This system consists of stimulation of human lymphocytes with a primary mitogen (anti-T-cell receptor complex antibodies (OKT3 or wt31)) and treatment with a primary immunosuppressive drug (ISD) (Cyclosporine A ...

journal_title：Immunopharmacology and immunotoxicology

authors： Weaver JL,Pine PS,Aszalos A

更新日期：1994-05-01 00:00:00

abstract：:Apigenin is a plant flavonoid and a pharmacologically active agent that has been isolated from several plant species. However, the molecular mechanism of apigenin-mediated immune modulation has not been fully understood. One of the possible mechanisms of its protective effects is the down-regulation of inflammatory re...

journal_title：Immunopharmacology and immunotoxicology

authors： Kang OH,Lee JH,Kwon DY

更新日期：2011-09-01 00:00:00

abstract：:The objective of the current study was to assess the effects of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) along with their simultaneous application on proliferation and pluripotency genes of murine adipose tissue-derived mesenchymal stem cells (AT-MSCs). The proliferation, doubling time (DT), colony-for...

journal_title：Immunopharmacology and immunotoxicology

authors： Mohammadpour H,Pourfathollah AA,Nikougoftar Zarif M,Hashemi SM

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Multiple organ dysfunction syndrome (MODS) is a major cause of death in critically patients. It has been hypothesized that inactivation or removal of pro-inflammatory molecules may prevent or reverse MODS. OBJECTIVE:The purpose of this paper was to investigate the efficacy of continuous veno-venous hemodiafilt...

journal_title：Immunopharmacology and immunotoxicology

authors： Chen J,Liu J,Yu C,Wen H

更新日期：2012-12-01 00:00:00

abstract：:Purple bamboo salt is a specially processed salt according to the traditional recipe using normal salt and bamboo. It has been used for the purpose of prevention and treatment of various diseases in Korea. We investigated the anti-inflammatory activity of purple bamboo salt by using human mast cell line (HMC-1). Purpl...

journal_title：Immunopharmacology and immunotoxicology

authors： Shin HY,Lee EH,Kim CY,Shin TY,Kim SD,Song YS,Lee KN,Hong SH,Kim HM

更新日期：2003-08-01 00:00:00

abstract：:CD69, also known as activation inducer molecule, very early activation antigen, MLR-3 and Leu-23, is a member of the natural killer (NK) cell gene complex family of signal transducing receptors. CD69 is as a type II transmembrane glycoprotein with a C-type lectin binding domain in the extracellular portion of the mole...

journal_title：Immunopharmacology and immunotoxicology

authors： Marzio R,Mauël J,Betz-Corradin S

更新日期：1999-08-01 00:00:00

abstract：:Physalin E is a naturally occurring seco-steroid isolated from the stems and aerial parts of Physalis angulata L. (Solanaceae). This study was aimed to explore the anti-inflammatory effects of physalin E on RAW 264.7 mouse macrophages stimulated by lipopolysaccharide (LPS) and the potential underlying mechanisms. The ...

journal_title：Immunopharmacology and immunotoxicology

authors： Yang YJ,Yi L,Wang Q,Xie BB,Dong Y,Sha CW

更新日期：2017-04-01 00:00:00

abstract：:We reported recently that a novel immunomodulator, 7-thia-8-oxoguanosine (7T8OG)2 inhibited formation of pulmonary melanoma metastases (1), prevented against viral infection in mice (2) and potentiated the efficacy of a weakly immunogenic leukemia vaccine (3). Since certain tumor metastases and virus infected cells ar...

journal_title：Immunopharmacology and immunotoxicology

authors： Sharma BS,Mhaskar S,Balazs L,Siaw M

更新日期：1992-01-01 00:00:00

abstract：:Formyl peptides are oligopeptides released by Gram-negative bacteria. So far, specific formyl peptide receptors (FPRs) have been described in mammals only. FPRs are seven-transmembrane G-coupled molecules and make up a relatively homogeneous group, although exhibiting different levels of affinity for the ligands. We e...

journal_title：Immunopharmacology and immunotoxicology

authors： Panaro MA,Acquafredda A,Sisto M,Lisi S,Calvello R,Mitolo CI,Cianciulli A,Mitolo V

更新日期：2007-01-01 00:00:00

abstract：:The effect of the opioid peptide dynorphin (DYN) on PHA-induced lymphocyte proliferation has been evaluated in the present study. A significant increase in PHA-induced lymphocyte activation was observed when DYN was added to cultures 48 hr after the mitogenic stimulation. This effect occurred at suboptimal (3.12 and 6...

journal_title：Immunopharmacology and immunotoxicology

authors： Barreca T,Di Benedetto G,Corsini G,Lenzi G,Puppo F

更新日期：1987-01-01 00:00:00

abstract：:This study aimed to evaluate the immunomodulatory effects of Pleurotus florida on cell-mediated immunity in Balb/c mice. Aqueous extract of P. florida was isolated, lyophilized, and stored in refrigerator until application. Forty female Balb/c mice were randomly divided into seven test and one control groups. Four gro...

journal_title：Immunopharmacology and immunotoxicology

authors： Sedaghat R,Ghazanfari T

更新日期：2011-03-01 00:00:00

abstract：:The popular murine macrophage cell line, RAW 264.7, is often used to initially screen natural products for bioactivity and to predict their potential effect in vivo or on primary cells. The cell line response is considered to reflect the potential human de novo response, and is used to evaluate the effective bioactivi...

journal_title：Immunopharmacology and immunotoxicology

authors： Merly L,Smith SL

更新日期：2017-04-01 00:00:00

abstract：:Spleen and thymus weight, delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC), contact hypersensitivity to picryl chloride, anti-sheep red blood cell hemagglutinin titers and plaque-forming cells (PFC), resistance against experimental toxoplasmosis as well as serum total and intestinal specific IgA wer...

journal_title：Immunopharmacology and immunotoxicology

authors： Brouland JP,Perriat A,Revillard JP,Descotes J

更新日期：1989-01-01 00:00:00