The deviated balance between regulatory T cell and Th17 in autoimmunity.

abstract：:Sexual assault was a ubiquitous and serious problem in our society. The world's care centers and forensic associations, which were at the forefront of scientific research in sexual assaults, discussed the role of the Forensic Nursing in their early diagnosis and their prevention, but little has been written in literat...

journal_title：Immunopharmacology and immunotoxicology

authors： Vitale E

更新日期：2012-04-01 00:00:00

abstract：:We investigated the effect of aqueous extract of Sanguisorba officinalis L.(Rosaceae) root (SOAE) on the immediate-type allergic reactions in vivo and in vitro. SOAE (0.01 to 1 g/kg) inhibited systemic allergic reaction induced by compound 48/80. When SOAE was employed in a systemic allergic reaction test, the plasma ...

journal_title：Immunopharmacology and immunotoxicology

authors： Shin TY,Lee KB,Kim SH

更新日期：2002-08-01 00:00:00

abstract：:The beta-subunits of thyroid stimulating hormone (TSH) and human chorionic gonadotropin (hCG) share a high homology, just like the ectodomains of their receptors, do. As a consequence, hCG was shown to exert a thyrotropic action in humans and hamsters. This study aimed to investigate whether hCG, used to induce ovulat...

journal_title：Immunopharmacology and immunotoxicology

authors： Rizzo A,Mutinati M,Spedicato M,Minoia G,Trisolini C,Punzi S,Roscino MT,Jirillo F,Sciorsci R

更新日期：2009-06-01 00:00:00

abstract：:Context: Pyocyanin is a typical Pseudomonas aeruginosa virulence factor, a common Gram-negative rod responsible for a wide range of severe nosocomial infections. There is evidence indicating that pyocyanin has multiple biological activities, but little is known about anti-inflammatory properties. Objective: This study...

journal_title：Immunopharmacology and immunotoxicology

authors： Marreiro de Sales-Neto J,Lima ÉA,Cavalcante-Silva LHA,Vasconcelos U,Rodrigues-Mascarenhas S

更新日期：2019-02-01 00:00:00

abstract：:We reported recently that a novel immunomodulator, 7-thia-8-oxoguanosine (7T8OG)2 inhibited formation of pulmonary melanoma metastases (1), prevented against viral infection in mice (2) and potentiated the efficacy of a weakly immunogenic leukemia vaccine (3). Since certain tumor metastases and virus infected cells ar...

journal_title：Immunopharmacology and immunotoxicology

authors： Sharma BS,Mhaskar S,Balazs L,Siaw M

更新日期：1992-01-01 00:00:00

abstract：:The effect of the opioid peptide dynorphin (DYN) on PHA-induced lymphocyte proliferation has been evaluated in the present study. A significant increase in PHA-induced lymphocyte activation was observed when DYN was added to cultures 48 hr after the mitogenic stimulation. This effect occurred at suboptimal (3.12 and 6...

journal_title：Immunopharmacology and immunotoxicology

authors： Barreca T,Di Benedetto G,Corsini G,Lenzi G,Puppo F

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND AIM:To probe into the effects of different doses of FK506 on endocrine function of pancreatic islets in Wistar rats. METHODS:Wistar rats were randomly divide into control group A (0mg/kg/d) and experimental group B (1mg/kg/d), C (3mg/kg/d), D (10mg/kg/d) treated with FK506. In an intraperitoneal glucose...

journal_title：Immunopharmacology and immunotoxicology

authors： Li F,Li Q

更新日期：2010-06-01 00:00:00

abstract：:Antidepressants are reported to display anti-inflammatory effects. Nitric oxide (NO), in turn, has a key role in inflammation. The objective of the present study was to evaluate the effect of amitriptyline co-administered with L-NAME (a NO synthase inhibitor) on certain parameters of acute inflammatory response in rat...

journal_title：Immunopharmacology and immunotoxicology

authors： Vismari L,Alves GJ,Muscará MN,Palermo-Neto J

更新日期：2012-08-01 00:00:00

abstract：:Ethanol has been recognized as an immunosuppressive agent for many years. Effects of high levels of ethanol consumption on immune functions have been extensively studied, but little is known about the effects of low levels (scuh as 5% ethanol) of ethanol consumption. Herein we report that exposure of mice to 5% ethano...

journal_title：Immunopharmacology and immunotoxicology

authors： Guo TL,Zhang LX,Chen JP,Nguyen VA,White KL Jr,Gao B

更新日期：2002-02-01 00:00:00

abstract：:We studied the effect of pyridoxine deficiency state on the responses of human lymphocytes to certain mitogenic factors. Deoxypyridoxine (DB6), a potent pyridoxine antagonist, considerably inhibited Bromodeoxyuridine (BrdU) incorporation into the newly synthesized DNA of lymphocytes cultured with Phytohemagglutinin (P...

journal_title：Immunopharmacology and immunotoxicology

authors： Scountzou J,Malisiovas N,Antoniadis A,Trakatellis A

更新日期：1989-01-01 00:00:00

abstract：:Experiments were performed to analyze the possible effect of the immunomodulating agent Pidotimod (3-L-pyroglutamyl-L-thiazolidine-4-carboxylic acid) on mouse Natural Killer (NK) cell activity and glucocorticoid hormone(GCH)-induced thymocyte apoptosis. The results indicate that in vivo treatment with Pidotimod (200 m...

journal_title：Immunopharmacology and immunotoxicology

authors： Migliorati G,D'Adamio L,Coppi G,Nicoletti I,Riccardi C

更新日期：1992-01-01 00:00:00

abstract：:Arecoline, a major alkaloid of arecanut was screened to explore its modulatory influence on cell-mediated immune response in a murine model system. The in vivo and in vitro effects were evaluated at subtoxic concentrations of arecoline. Delayed type hypersensitivity (DTH) reactions to sheep red blood cells (SRBC) were...

journal_title：Immunopharmacology and immunotoxicology

authors： Selvan RS,Selvakumaran M,Rao AR

更新日期：1991-01-01 00:00:00

abstract：:We examined the effect of sulfapyridine on mast cell-mediated immediate-type allergic reactions. Sulfapyridine (1 and 10 microg/kg) significantly inhibited systemic allergic reaction induced by compound 48/80 in rats. Sulfapyridine (1 and 10 microg/kg) also inhibited significantly local mast cell-mediated immediate-ty...

journal_title：Immunopharmacology and immunotoxicology

authors： Kim HM,An NH,Yi BH,Chae HJ,Kim HR,Moon SJ,Kim JJ,Park ST,Baek SH

更新日期：2000-05-01 00:00:00

abstract：:Snakebites in rural areas of tropical and subtropical regions are commonly treated with medicinal plants. In this report, we have studied the ability of Anacardium occidentale bark extract to neutralize enzymatic as well as pharmacological effects induced by Vipera russelii venom. The extract neutralized the viper ven...

journal_title：Immunopharmacology and immunotoxicology

authors： Ushanandini S,Nagaraju S,Nayaka SC,Kumar KH,Kemparaju K,Girish KS

更新日期：2009-01-01 00:00:00

abstract：:Abstract Alpinetin, a flavonoid compound extracted from the seeds of Alpinia katsumadai Hayata, has been known to possess antibacterial, anti-inflammatory and other important therapeutic activities. In the current study, we investigated alpinetin for its immunosuppressive effect on activation and cytokines secretion o...

journal_title：Immunopharmacology and immunotoxicology

authors： Guan S,Fang B,Song B,Xiong Y,Lu J

更新日期：2014-08-01 00:00:00

abstract：:Physalin E is a naturally occurring seco-steroid isolated from the stems and aerial parts of Physalis angulata L. (Solanaceae). This study was aimed to explore the anti-inflammatory effects of physalin E on RAW 264.7 mouse macrophages stimulated by lipopolysaccharide (LPS) and the potential underlying mechanisms. The ...

journal_title：Immunopharmacology and immunotoxicology

authors： Yang YJ,Yi L,Wang Q,Xie BB,Dong Y,Sha CW

更新日期：2017-04-01 00:00:00

abstract：CONTEXT:Foeniculum vulgare (F. vulgare) is traditionally used to treat inflammatory diseases. Recently, anti-inflammatory and antioxidant activities of methanol extract of the fruits of F. vulgare were reported. To identify biologically active compounds responsible for the anti-inflammatory activity, we isolated four c...

journal_title：Immunopharmacology and immunotoxicology

authors： Yang IJ,Lee DU,Shin HM

更新日期：2015-06-01 00:00:00

abstract：:Traditionally venoms are used from thousands of years to treat pain, inflammation, and arthritis. In Ayurveda "Suchika Voron" and "Shodhona" were practiced against pain. In the present study, venom composition of the Indian honeybee Apis florea (AF), Apis dorsata (AD), and Apis cerana indica (AC) were analyzed using e...

journal_title：Immunopharmacology and immunotoxicology

authors： Nipate SS,Hurali PB,Ghaisas MM

更新日期：2015-04-01 00:00:00

abstract：:Engystol-N at the doses of 10(-4) and 10(-8) in isolated human leukocytes stimulates the superoxide anion generation by neutrophils and the cytokine(s) production by T lymphocytes. In whole blood the same concentrations of the drug produce the decrease of the superoxide anion generation of neutrophils, this inhibiting...

journal_title：Immunopharmacology and immunotoxicology

authors： Fimiani V,Cavallaro A,Ainis O,Bottari C

更新日期：2000-02-01 00:00:00

abstract：:Apigenin is a plant flavonoid and a pharmacologically active agent that has been isolated from several plant species. However, the molecular mechanism of apigenin-mediated immune modulation has not been fully understood. One of the possible mechanisms of its protective effects is the down-regulation of inflammatory re...

journal_title：Immunopharmacology and immunotoxicology

authors： Kang OH,Lee JH,Kwon DY

更新日期：2011-09-01 00:00:00

abstract：:A substantial body of research exists to support the production of growth hormone by cells of the immune system. However, the function and mechanism of action of lymphocyte-derived growth hormone remain largely unelucidated. Since, it has been found that exogenous growth hormone (GH) primes neutrophils for the product...

journal_title：Immunopharmacology and immunotoxicology

authors： Arnold RE,Weigent DA

更新日期：2003-05-01 00:00:00

abstract：:We examined the effects of interferon (IFN)beta-1a on interleukin (IL)-12p70 and IL-10 secretion in 27 Relapsing Remitting Multiple Sclerosis (RRMS) patients, divided in responders and non-responders. In responders, IFNbeta-1a does not change the IL-12p70 concentrations, but it leads to a remarkable increase in the IL...

journal_title：Immunopharmacology and immunotoxicology

authors： Carrieri PB,Ladogana P,Di Spigna G,de Leva MF,Petracca M,Montella S,Buonavolontà L,Florio C,Postiglione L

更新日期：2008-01-01 00:00:00

abstract：:The modulatory effect of FK 506 and cyclosporin A (CsA) on the expression of inducible nitric oxide synthase (iNOS) in macrophages and mechanisms of their action were analysed. Isolated rat peritoneal macrophages were cultured for 12 or 24 h with or without lipopolysaccharide (LPS) (5 microg/ml) and in the absence or ...

journal_title：Immunopharmacology and immunotoxicology

authors： Strestíková P,Otová B,Filipec M,Masek K,Farghali H

更新日期：2001-02-01 00:00:00

abstract：:A competitive enzyme-linked immunosorbent assay (ELISA) with generated mouse anti-consensus interferon (CIFN) antibody was developed for quantitative determination of pegylated consensus interferon (PEG-CIFN) in rhesus monkey serum. The operational concentrations of the original assay were determined using the chessbo...

journal_title：Immunopharmacology and immunotoxicology

authors： Cao J,Du Y,Tian H,Gao XD,Yao WB

更新日期：2009-01-01 00:00:00

abstract：:Enhanced glucose utilization was observed in continuous cultures of macrophages in medium containing 4mM Quadrol, [N,N,N',N',Tetrakis(2-hydroxypropyl)ethylenediamine]. This enhancement was both time and concentration dependent. Radiolabeled 4mM Quadrol, after incubation with macrophages for 60 minutes, was shown to be...

journal_title：Immunopharmacology and immunotoxicology

authors： Bhide MV,Smith DJ

更新日期：1987-01-01 00:00:00

abstract：:Angiogenesis, the process of new capillary formation from pre-existing vessels, has been established as an important mechanism involved in pathologic processes, such as cancer, as well as in normal physiology (Ribatti, D.; Vacca, A.; Roncali, L.; Dammacco, F. Angiogenesis under normal and pathological conditions. Haem...

journal_title：Immunopharmacology and immunotoxicology

authors： Plum SM,Vu HA,Mercer B,Fogler WE,Fortier AH

更新日期：2004-02-01 00:00:00

abstract：:Reynoutria elliptica has been used in traditional Korean medicine to promote blood circulation, relieve pain, increase dieresis, and alleviate respiratory problems, through as yet undefined mechanisms. We set out to determine whether the anti-inflammatory effects of this plant are linked with its ability to suppress m...

journal_title：Immunopharmacology and immunotoxicology

authors： Lee G,Choi TW,Kim C,Nam D,Lee SG,Jang HJ,Lee JH,Um JY,Jung SH,Shim BS,Ahn KS,Ahn KS

更新日期：2012-06-01 00:00:00

abstract：:The protective effects of baicalin (BA), a major flavone from Scutellaria radix, on acetaminophen (AP)-induced hepatotoxicity and the possible mechanism(s) of its protective action were investigated in mice. Treatment with BA (300 mg/kg, p.o.) 0.5 h after AP administration significantly prevented an increase in plasma...

journal_title：Immunopharmacology and immunotoxicology

authors： Jang SI,Kim HJ,Hwang KM,Jekal SJ,Pae HO,Choi BM,Yun YG,Kwon TO,Chung HT,Kim YC

更新日期：2003-11-01 00:00:00

abstract：:We have developed an in vitro system to model the interactions of drugs used to treat transplant rejection. This system consists of stimulation of human lymphocytes with a primary mitogen (anti-T-cell receptor complex antibodies (OKT3 or wt31)) and treatment with a primary immunosuppressive drug (ISD) (Cyclosporine A ...

journal_title：Immunopharmacology and immunotoxicology

authors： Weaver JL,Pine PS,Aszalos A

更新日期：1994-05-01 00:00:00

abstract：:Naloxone at concentrations 10(-6) M to 10(-10) M modulated endogenous NK-activity in 11 of 14 samples of human peripheral blood lymphocytes after 18-hour incubation. The dose response usually showed two peaks, which varied with the donor. Enhancement was obtained in 6, suppression in 4, and both effects (depending on ...

journal_title：Immunopharmacology and immunotoxicology

authors： Martin-Kleiner I,Gabrilovac J

更新日期：1993-03-01 00:00:00