The anti-ophidian properties of Anacardium occidentale bark extract.

abstract：:We investigated the effect of aqueous extract of Sanguisorba officinalis L.(Rosaceae) root (SOAE) on the immediate-type allergic reactions in vivo and in vitro. SOAE (0.01 to 1 g/kg) inhibited systemic allergic reaction induced by compound 48/80. When SOAE was employed in a systemic allergic reaction test, the plasma ...

journal_title：Immunopharmacology and immunotoxicology

authors： Shin TY,Lee KB,Kim SH

更新日期：2002-08-01 00:00:00

abstract：:Mercuric sulfide (HgS) is a major component of cinnabar, which has been used as a sedative drug in China for more than 2000 years. Because its toxicological effects are still unclear, we attempted to verify the toxic effects of HgS, focused on liver and immune organs such as the spleen and thymus. Male ICR mice were a...

journal_title：Immunopharmacology and immunotoxicology

authors： Son HY,Lee S,Park SB,Kim MS,Choi EJ,Singh TS,Bae Y,Kwack SJ,Kang TS,Shin HI,Baek MC,Kim SH

更新日期：2010-06-01 00:00:00

abstract：:We examined the effect of sulfapyridine on mast cell-mediated immediate-type allergic reactions. Sulfapyridine (1 and 10 microg/kg) significantly inhibited systemic allergic reaction induced by compound 48/80 in rats. Sulfapyridine (1 and 10 microg/kg) also inhibited significantly local mast cell-mediated immediate-ty...

journal_title：Immunopharmacology and immunotoxicology

authors： Kim HM,An NH,Yi BH,Chae HJ,Kim HR,Moon SJ,Kim JJ,Park ST,Baek SH

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) is a chronic skin inflammatory disease characterized by disequilibrium between Th1/Th2 lymphocytes. Helicobacter pylori neutrophil-activating protein (HP-NAP) has been reported that it has the potential immunomodulatory effect able to regulate the Th1/Th2 balance. OBJECTIVE:This study...

journal_title：Immunopharmacology and immunotoxicology

authors： Guo X,Ding C,Lu J,Zhou T,Liang T,Ji Z,Xie P,Liu X,Kang Q

更新日期：2020-10-01 00:00:00

abstract：:The aim pf the present study was to characterize the time course of the synthesis of mRNA encoding interleukin-2 (IL-2) by peripheral blood mononuclear cells (PBMCs) isolated from nickel-allergic women and subsequently exposed to nickel sulphate in vitro. The level of this mRNA (determined by employing real-time polym...

journal_title：Immunopharmacology and immunotoxicology

authors： Falsafi-Amin H,Holst M,Lundeberg L

更新日期：2008-01-01 00:00:00

abstract：CONTEXT:Velvet antler (VA) is recognized as one of the most important Chinese traditional medical herbs. To date, the immunoactivity of the single component of VA is rarely studied though its compound extracts have been well analyzed. OBJECTIVE:The current study was designed to evaluate the immunomodulatory effects of...

journal_title：Immunopharmacology and immunotoxicology

authors： Zha E,Dandan L,Bai X,Zhou T,Li Y,Shenyang G,Yue X

更新日期：2016-12-01 00:00:00

abstract：:The effect of rapamycin (RAPA) on kidney function and histopathology was assessed in two strains of mice. Male C3H/HeJ mice were treated with RAPA for 4 days at doses of 25, 50, 75, and 100 mg/kg, ip and male C3H/HeJ or female Balb/cJ mice were both treated for 7 days at doses of 75, 150 and 200 mg/kg. Cyclosporine (C...

journal_title：Immunopharmacology and immunotoxicology

authors： Di Joseph JF,Sehgal SN

更新日期：1993-01-01 00:00:00

abstract：:The effect that MnCl2 has on murine splenic natural killer (NK) cell activity was investigated in infant (10 days old), pre-weanling (18 days old) and weanling (24 days old) C57BL/6J mice. A single intraperitoneal injection of 10, 20 or 40 micrograms MnCl2/g body weight caused a significant enhancement in NK activity,...

journal_title：Immunopharmacology and immunotoxicology

authors： Smialowicz RJ,Riddle MM,Rogers RR,Luebke RW,Burleson GR

更新日期：1988-01-01 00:00:00

abstract：:We examined the effects of interferon (IFN)beta-1a on interleukin (IL)-12p70 and IL-10 secretion in 27 Relapsing Remitting Multiple Sclerosis (RRMS) patients, divided in responders and non-responders. In responders, IFNbeta-1a does not change the IL-12p70 concentrations, but it leads to a remarkable increase in the IL...

journal_title：Immunopharmacology and immunotoxicology

authors： Carrieri PB,Ladogana P,Di Spigna G,de Leva MF,Petracca M,Montella S,Buonavolontà L,Florio C,Postiglione L

更新日期：2008-01-01 00:00:00

abstract：:We have previously obtained and elucidated the precise structure of a highly branched 1,3-β-D-glucan (with 6-monoglucopyranosyl side chains), Aureobasidium pullulans-fermented β-D-glucan (AP-FBG), from the fungus A. pullulans. However, the mechanism(s) of the effects of AP-FBG on in vitro mouse primary cells have not ...

journal_title：Immunopharmacology and immunotoxicology

authors： Tada R,Yoshikawa M,Kuge T,Tanioka A,Ishibashi K,Adachi Y,Tsubaki K,Ohno N

更新日期：2011-06-01 00:00:00

abstract：:Experiments were performed to analyze the possible effect of the immunomodulating agent Pidotimod (3-L-pyroglutamyl-L-thiazolidine-4-carboxylic acid) on mouse Natural Killer (NK) cell activity and glucocorticoid hormone(GCH)-induced thymocyte apoptosis. The results indicate that in vivo treatment with Pidotimod (200 m...

journal_title：Immunopharmacology and immunotoxicology

authors： Migliorati G,D'Adamio L,Coppi G,Nicoletti I,Riccardi C

更新日期：1992-01-01 00:00:00

abstract：INTRODUCTION AND AIMS:N-Acetyl-β-D-glucosaminidase (NAG), a marker of renal tubular dysfunction, is increased in patients with lupus nephritis. In addition to the toxic effects of proteinuria, patients with lupus nephritis may exhibit other factors that contribute to tubular dysfunction, such as pathogenic antitubular ...

journal_title：Immunopharmacology and immunotoxicology

authors： Gluhovschi C,Velciov S,Kaycsa A,Gluhovschi G,Petrica L,Marian R,Bozdog G,Gadalean F,Bob F,Cioca D,Vernic C

更新日期：2012-02-01 00:00:00

abstract：:The objective of the current study was to assess the effects of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) along with their simultaneous application on proliferation and pluripotency genes of murine adipose tissue-derived mesenchymal stem cells (AT-MSCs). The proliferation, doubling time (DT), colony-for...

journal_title：Immunopharmacology and immunotoxicology

authors： Mohammadpour H,Pourfathollah AA,Nikougoftar Zarif M,Hashemi SM

更新日期：2016-01-01 00:00:00

abstract：:Swiss Webster mice were exposed to excess dietary aluminum (Al) (1000 micrograms Al/g diet, Al as Al lactate) from conception to 6 months of age. Splenic lymphocytes (10(6) per culture) were incubated for 24 hrs with concanavalin A (5 micrograms/ml). Concentrations of interleukin-2, interferon-gamma and tumor necrosis...

journal_title：Immunopharmacology and immunotoxicology

authors： Golub MS,Takeuchi PT,Gershwin ME,Yoshida SH

更新日期：1993-11-01 00:00:00

abstract：:Context: Pyocyanin is a typical Pseudomonas aeruginosa virulence factor, a common Gram-negative rod responsible for a wide range of severe nosocomial infections. There is evidence indicating that pyocyanin has multiple biological activities, but little is known about anti-inflammatory properties. Objective: This study...

journal_title：Immunopharmacology and immunotoxicology

authors： Marreiro de Sales-Neto J,Lima ÉA,Cavalcante-Silva LHA,Vasconcelos U,Rodrigues-Mascarenhas S

更新日期：2019-02-01 00:00:00

abstract：:Langerhans cells (LC) are immature dendritic cells (DC) present in the skin epithelium. To understand the molecular and cellular mechanisms governing the inflammatory reaction in atopic dermatitis (AD), the expression of the LC specific marker CD1a, a member of major histocompatibility (MHC)-like glycoproteins, and th...

journal_title：Immunopharmacology and immunotoxicology

authors： Fesenkova VI,Kurchenko AI,Castellani ML,Conti P,Anogeianaki A,Caraffa A,Kalogeromitros D

更新日期：2007-01-01 00:00:00

abstract：:Heavy metals administered to animals, at doses which appear relatively innoxious by themselves, enhance susceptibility to endotoxin. The mechanisms which underly this phenomenon are not yet fully understood. In this study we investigated the role of the cytokine Tumour Necrosis Factor (TNF), an important mediator of t...

journal_title：Immunopharmacology and immunotoxicology

authors： Dentener MA,Greve JW,Maessen JG,Buurman WA

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Sorafenib is an orally active multikinase inhibitor licensed for the treatment of patients with unresectable hepatocellular carcinoma (HCC). PATIENTS AND METHODS:The web-based registry, used for appraisal on new drugs, allows developing the observational prospective analysis of innovative drug therapies. To...

journal_title：Immunopharmacology and immunotoxicology

authors： Trojniak MP,Palozzo AC,Mazurek M,Jirillo A

更新日期：2012-06-01 00:00:00

abstract：:The aim of the present investigation was to evaluate the efficacy of Withania somnifera on tricarboxylic acid (TCA) cycle enzymes and electron transport chain in azoxymethane-induced experimental colon cancer in mice. Azoxymethane at the dose of 15 mg/kg body weight was induced intraperitoneally once in a week for 28 ...

journal_title：Immunopharmacology and immunotoxicology

authors： Muralikrishnan G,Amanullah S,Basha MI,Dinda AK,Shakeel F

更新日期：2010-09-01 00:00:00

abstract：:Tubeimoside-1 (TBMS1) is one of the important components in Bolbostemma paniculatum (Maxim.) Franque. In the study, its immunosuppressive effects on murine T lymphocyte responses were evaluated in vitro and in vivo. The data showed that TBMS1 inhibited ConA-induced T lymphocyte proliferation, decreased the ratio of CD...

journal_title：Immunopharmacology and immunotoxicology

authors： Huang Y,Ren M,Xiong Y,Wang T,Chen H,Deng X,Lu J

更新日期：2015-01-01 00:00:00

abstract：:The application of heat shock to different types of cells is known to cause multiple biochemical and metabolic changes. The predominant event though is an increased synthesis and expression of a family of proteins, the heat-shock proteins (Hsp). Some of these proteins are currently considered to be involved in the sig...

journal_title：Immunopharmacology and immunotoxicology

authors： Liossis SN,Tsokos GC

更新日期：1997-11-01 00:00:00

abstract：:Taraxasterol, a pentacyclic-triterpene, was isolated from the Chinese medicinal herb Taraxacum officinale. In the present study, we investigated the protective effect of taraxasterol on murine model of endotoxic shock and the mechanism of its action. Mice were treated with 2.5, 5 and 10 mg/kg of taraxasterol prior to ...

journal_title：Immunopharmacology and immunotoxicology

authors： Zhang X,Xiong H,Li H,Cheng Y

更新日期：2014-02-01 00:00:00

abstract：:Physalin E is a naturally occurring seco-steroid isolated from the stems and aerial parts of Physalis angulata L. (Solanaceae). This study was aimed to explore the anti-inflammatory effects of physalin E on RAW 264.7 mouse macrophages stimulated by lipopolysaccharide (LPS) and the potential underlying mechanisms. The ...

journal_title：Immunopharmacology and immunotoxicology

authors： Yang YJ,Yi L,Wang Q,Xie BB,Dong Y,Sha CW

更新日期：2017-04-01 00:00:00

abstract：:In 15 elderly individuals lyophilized Bifidobacterium bifidum (BB) and Lactobacillus acidophilus (LA) (Infloran) were administered in capsules (two capsules 4 times per day) for 28 days, while in 10 elderly controls placebo were given the same posology and for an equal period of time. The effects of this treatment on ...

journal_title：Immunopharmacology and immunotoxicology

authors： De Simone C,Ciardi A,Grassi A,Lambert Gardini S,Tzantzoglou S,Trinchieri V,Moretti S,Jirillo E

更新日期：1992-01-01 00:00:00

abstract：:Chronic administration of oxytetracycline (OXT) (incorporated at a level of 0.05 g per kg of feed for 50 days) to pigeons, significantly decreased total leukocyte and lymphocyte counts, increased heterophil:lymphocyte ratio and lysosomal enzyme activity, and decreased reticuloendothelial system function compared with ...

journal_title：Immunopharmacology and immunotoxicology

authors： Al-Ankari AS

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Abnormal microglia secrete neuroinflammatory factors that play a pivotal role in neurodegenerative-disorder development. Thus, regulating abnormal microglia-activation could be a promising therapeutic strategy. The purposes of this study included investigating the effect of Petatewalide B on lipopolysacchari...

journal_title：Immunopharmacology and immunotoxicology

authors： Park SY,Choi MH,Li M,Li K,Park G,Choi YW

更新日期：2018-06-01 00:00:00

abstract：:A competitive enzyme-linked immunosorbent assay (ELISA) with generated mouse anti-consensus interferon (CIFN) antibody was developed for quantitative determination of pegylated consensus interferon (PEG-CIFN) in rhesus monkey serum. The operational concentrations of the original assay were determined using the chessbo...

journal_title：Immunopharmacology and immunotoxicology

authors： Cao J,Du Y,Tian H,Gao XD,Yao WB

更新日期：2009-01-01 00:00:00

abstract：:Lung cancer continues to be the leading cause of cancer deaths and more than one million lung cancer patients will die every year worldwide. Radiotherapy (RT) plays an important role in lung cancer treatment, but the side effects of RT are pneumonitis and pulmonary fibrosis. RT-induced lung injury causes damage to alv...

journal_title：Immunopharmacology and immunotoxicology

authors： S N SG,Raviraj R,Nagarajan D,Zhao W

更新日期：2019-06-01 00:00:00

abstract：:Increased numbers of myeloid-derived suppressor cells (MDSCs) are often observed in various pathological and physiological conditions. However, the interactions between neurotransmitters and MDSCs have not been elucidated. In this study, we studied whether norepinephrine (NE), a neurotransmitter, could affect the diff...

journal_title：Immunopharmacology and immunotoxicology

authors： Liu Y,Wei J,Guo G,Zhou J

更新日期：2015-01-01 00:00:00

abstract：:The immunological effects of interferon (IFN)-alpha administration were evaluated in 15 patients with cHCV infection. Individuals were treated with 6 MU of lymphoblastoid IFN-alpha three times a week for 6 months and with 3 MU three times a week for an additional 6 months. Patients were divided into responders (12 sub...

journal_title：Immunopharmacology and immunotoxicology

authors： Jirillo E,Greco B,Caradonna L,Satalino R,Amati L,Cozzolongo R,Cuppone R,Manghisi OG

更新日期：1996-08-01 00:00:00