Immunomodulating effects of black seed and oxytetracycline in pigeons.

Abstract:

:Chronic administration of oxytetracycline (OXT) (incorporated at a level of 0.05 g per kg of feed for 50 days) to pigeons, significantly decreased total leukocyte and lymphocyte counts, increased heterophil:lymphocyte ratio and lysosomal enzyme activity, and decreased reticuloendothelial system function compared with controls. Coadministration of black seed (BS) at a level of 2.5% with OXT completely blocked the effects elicited by OXT and produced immunostimulant effects in pigeons. The addition of BS to feed of pigeons could act as an immunoprotective agent when chronic administration of antibiotics are considered.

authors

Al-Ankari AS

doi

10.1080/08923970500242327

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

515-20

issue

3

eissn

0892-3973

issn

1532-2513

journal_volume

27

pub_type

杂志文章
  • Polyclonal stimulation of lymphocytes induced by beta blockers in the mouse: influences of age, sex and strain.

    abstract::The immune effects of acebutolol, a beta-blocker, are investigated in various strains of mice. In 6-12 weeks old C57Bl/6 female mice, an increase in the number of immunoglobulin secreting cells is observed only at the age of 9 weeks. At that age, such an effect is seen neither in C57Bl/6 male mice nor in female mice f...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923979009019668

    authors: In S,Lulé J,Fournié GJ

    更新日期:1990-01-01 00:00:00

  • Enhancement of lymphocyte proliferation and IL-2 receptor expression by a processed form (GM-1/P) of monosialoganglioside GM-1.

    abstract::In this study we investigated the ability of GM-1/P, a calcium mediated processed form of monosialoganglioside GM-1, of in vivo augmenting mouse T and B-lymphocyte blastogenesis induced by mitogens. We have also determined its effect on IL-2 responsiveness by analyzing the induction of the expression of IL-2 receptor ...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923979009019677

    authors: Giuffrida A,Morrone S,Gismondi A,Santoni G,Punturieri A,Velotti F,Cavallo G,Tubaro E,Piccoli M,Frati L

    更新日期:1990-01-01 00:00:00

  • Preclinical assessment of β-d-mannuronic acid (M2000) as a non-steroidal anti-inflammatory drug.

    abstract:CONTEXT:β-d-Mannuronic acid (M2000) has shown its therapeutic effects with the greatest tolerability and efficacy in various experimental models such as experimental autoimmune encephalomyelitis (EAE), adjuvant induced arthritis (AIA), nephrotic syndrome, and acute glomerulonephritis. Despite pharmacological effects of...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923973.2015.1113296

    authors: Fattahi MJ,Abdollahi M,Agha Mohammadi A,Rastkari N,Khorasani R,Ahmadi H,Tofighi Zavareh F,Sedaghat R,Tabrizian N,Mirshafiey A

    更新日期:2015-01-01 00:00:00

  • Silica induced suppression of the production of third and fifth components of the complement system by human lung cells in vitro.

    abstract::Although investigations to date have demonstrated the ability of the monocyte/macrophage to synthesize complement components, only a limited number of studies on complement synthesis by nonhepatic tissue cells have been reported. To begin to fill this gap in our knowledge we have recently evaluated the ability of lung...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923979409019738

    authors: Rothman BL,Contrino J,Merrow M,Despins A,Kennedy T,Kreutzer DL

    更新日期:1994-11-01 00:00:00

  • Clerodendron glandulosum.Coleb leaf extract attenuates in vitro macrophage differentiation and expression of VCAM-1 and P-selectin in thoracic aorta of atherogenic diet fed rats.

    abstract::Present inventory evaluates the anti-atherogenic potential of C. glandulosum.Coleb leaf extract (CG) using in vivo and in vitro experimental models. Serum markers of low density lipoprotein (LDL-C) oxidation, cholesterol, triglycerides, lipoproteins, auto-antibody titer, ex vivo LDL-C oxidation, LDL-C aggregation, aor...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923973.2011.618136

    authors: Jadeja RN,Thounaojam MC,Jain M,Devkar RV,Ramachandran AV

    更新日期:2012-06-01 00:00:00

  • Structural similarities between mRNA for the formyl peptide receptors and 18S rRNA.

    abstract::Formyl peptides released by some bacteria are powerful chemoattractants and activators of mammalian granulocytes and monocytes, acting through 7-transmembrane specific formyl peptide receptors (FPRs). Three distinct segments of the formyl peptide receptor 1 (FPR1) mRNA of Man share probabilistically significant homolo...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1081/iph-200067768

    authors: Panaro MA,Acquafredda A,Sisto M,Lisi S,Calvello R,Saccia M,Maffione AB,Mitolo V

    更新日期:2005-01-01 00:00:00

  • Pharmacokinetics of Cyclosporine A in Chinese heart transplant recipients.

    abstract:AIM:To determine the steady state concentration and the pharmacokinetics of Cyclosporine A (CsA) in heart transplant recipients. METHODS:A single dose of 100 mg CsA capsules twice daily was given to five heart transplant recipients of steady state. The concentrations of CsA in plasma were determined by streptavidin pe...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 临床试验,杂志文章

    doi:10.3109/08923973.2011.613400

    authors: Jin R,Duan H,Zhao C,Wang Z,Qu F

    更新日期:2012-06-01 00:00:00

  • Carvacrol ameliorates the progression of liver fibrosis through targeting of Hippo and TGF-β signaling pathways in carbon tetrachloride (CCl4)-induced liver fibrosis in rats.

    abstract::Objective: Little is known about the exact underlying molecular mechanisms of the hepatoprotective effect of carvacrol against liver fibrosis. In the current study, we aimed to investigate the effect of carvacrol on the suppression of liver fibrosis progression via regulation of yes-associated protein (YAP) and transc...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1080/08923973.2019.1566926

    authors: Mohseni R,Karimi J,Tavilani H,Khodadadi I,Hashemnia M

    更新日期:2019-02-01 00:00:00

  • Anti-inflammatory activity of Korean folk medicine purple bamboo salt.

    abstract::Purple bamboo salt is a specially processed salt according to the traditional recipe using normal salt and bamboo. It has been used for the purpose of prevention and treatment of various diseases in Korea. We investigated the anti-inflammatory activity of purple bamboo salt by using human mast cell line (HMC-1). Purpl...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1081/iph-120024505

    authors: Shin HY,Lee EH,Kim CY,Shin TY,Kim SD,Song YS,Lee KN,Hong SH,Kim HM

    更新日期:2003-08-01 00:00:00

  • Bleomycin and FK 565 enhance the release of GM-CSF from LPS-stimulated BALB/c peritoneal macrophages.

    abstract::The anti-tumour antibiotic Bleomycin, the experimental immunostimulatory tripeptide FK 565, and the immunosuppressive agent Cyclosporin A were examined for their in vitro effects on the release of the haemopoietic cytokine Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) from LPS stimulated BALB/c adherent pe...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923979509016381

    authors: Blaney BA,Turk JL

    更新日期:1995-08-01 00:00:00

  • Aqueous extract of Rhodiola imbricata rhizome stimulates proinflammatory mediators via phosphorylated IkappaB and transcription factor nuclear factor-kappaB.

    abstract::Modulation of immune response to alleviate diseases has long since been of interest. Plant extracts have been widely investigated for their possible immunomodulatory properties. We have evaluated the immunomodulatory activity of aqueous extract of Rhodiola rhizome in human peripheral blood mononuclear cells (PBMCs) an...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1080/08923970600815139

    authors: Mishra KP,Padwad YS,Jain M,Karan D,Ganju L,Sawhney RC

    更新日期:2006-01-01 00:00:00

  • Comparison of FK 506, mycophenolate mofetil, and aminoguanidine effects on delay of corneal allograft rejection in an experimental model of low-risk and high-risk keratoplasty.

    abstract::The purpose of our study was to compare the effectiveness of immunosuppressive drugs on the prevention of allograft rejection in a murine model of low-risk and high-risk keratoplasty. The therapy included FK 506 (tacrolimus; 0.2 mg/kg), mycophenolate mofetil (30 mg/kg), aminoguanidine (0.1 g/kg), and combination of FK...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1080/08923970600809447

    authors: Svozílková P,Bysterská P,Masek K,Valenta Z,Zvárová J,Farghali H

    更新日期:2006-01-01 00:00:00

  • Effect of rifampicin to inhibit rapamycin-induced autophagy via the suppression of protein phosphatase 2A activity.

    abstract::Recently, a number of studies have focused on the secondary effects of rifampicin. In the present study, we assessed whether rifampicin influences the rapamycin-induced autophagy of RAW 264.7 cells. Here, we demonstrate that the rapamycin-induced autophagy is dependent on protein phosphatase (PP) 2A activity and rifam...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1080/08923970802135732

    authors: Park IH,Yeum CE,Chae GT,Lee SB

    更新日期:2008-01-01 00:00:00

  • Toxic effects of mercuric sulfide on immune organs in mice.

    abstract::Mercuric sulfide (HgS) is a major component of cinnabar, which has been used as a sedative drug in China for more than 2000 years. Because its toxicological effects are still unclear, we attempted to verify the toxic effects of HgS, focused on liver and immune organs such as the spleen and thymus. Male ICR mice were a...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923970903305499

    authors: Son HY,Lee S,Park SB,Kim MS,Choi EJ,Singh TS,Bae Y,Kwack SJ,Kang TS,Shin HI,Baek MC,Kim SH

    更新日期:2010-06-01 00:00:00

  • PRBC-derived plasma induces non-muscle myosin type IIA-mediated neutrophil migration and morphologic change.

    abstract:CONTEXT:Neutrophils are the primary effector cells in the pathogenesis of transfusion-related acute lung injury or multiple organ failure after blood transfusion. OBJECTIVE:We aimed to investigate the effect of fresh (1 day preparation) and aged (42 day preparation) PRBC-derived plasma on neutrophil morphology, migrat...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923973.2012.677046

    authors: Yu C,Xu L,Chen LF,Guan YJ,Kim M,Biffl WL,Chin YE

    更新日期:2013-02-01 00:00:00

  • A recombinant polypeptide from velvet antler of Cervus nippon Temminck exhibits similar immunomodulatory effects as its natural counterpart.

    abstract:CONTEXT:Velvet antler (VA) is recognized as one of the most important Chinese traditional medical herbs. To date, the immunoactivity of the single component of VA is rarely studied though its compound extracts have been well analyzed. OBJECTIVE:The current study was designed to evaluate the immunomodulatory effects of...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1080/08923973.2016.1233978

    authors: Zha E,Dandan L,Bai X,Zhou T,Li Y,Shenyang G,Yue X

    更新日期:2016-12-01 00:00:00

  • Ex vivo triggering of T-cell-mediated immune responses by autologous tumor cell vaccine in oral cancer patients.

    abstract::We investigated immunomodulatory activity of autologous tumor cell vaccine from oral cancer patients ex vivo by lymphoproliferation assay and two color flow cytometry. Vaccine treatment lead to 10-fold higher proliferation of lymphocytes compared with the untreated controls. A significant increase in CD69(+) and HLA-D...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 临床试验,杂志文章

    doi:10.1080/08923970701282742

    authors: Agarwal A,Mohanti BK,Das SN

    更新日期:2007-01-01 00:00:00

  • Anti-angiogenic activity of Ipomoea obscura extract and Ipobscurine-A.

    abstract:OBJECTIVE:Ipomoea obscura (L.) Ker-Gawl, is a medicinal herb with indole alkaloids as an active constituent. In this study, we investigated the anti-angiogenic activity of I. obscura extract and one of its major compounds Ipobscurine-A (IPO-A). METHODS:In vivo angiogenesis was induced by injecting B16F10 melanoma cell...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923973.2010.531277

    authors: Hamsa TP,Kuttan G

    更新日期:2011-09-01 00:00:00

  • Suppressive and enhancing effect of T-2 toxin on murine lymphocyte activation and interleukin 2 production.

    abstract::T-2 toxin, a fungal metabolite shown previously to exert potent immunosuppressive effects, was examined for its effects on activation and interleukin 2 (IL 2) production by murine and rat splenocytes. Splenocytes (1 X 10(6) cells/well) were incubated with 1 microgram Concanavalin A (Con A) for 48 h at which time cellu...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923978809041427

    authors: Holt PS,Corrier DE,DeLoach JR

    更新日期:1988-01-01 00:00:00

  • Ginsenoside metabolite compound K attenuates inflammatory responses of adjuvant-induced arthritis rats.

    abstract:OBJECTIVE:To investigate the effects of ginsenoside metabolite compound K (CK) on adjuvant-induced arthritis (AA) rats and the partial mechanisms focused on the function of immunocyte (B cell and macrophage) and effectors' cell (fibroblast-like synoviocyte, FLS). METHODS:Animals were divided randomly into nine groups ...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923973.2014.880717

    authors: Wu H,Chen J,Wang Q,Jia X,Song S,Yuan P,Liu K,Liu L,Zhang Y,Zhou A,Wei W

    更新日期:2014-04-01 00:00:00

  • Cyclosporin-A augments respiratory burst of whole blood phagocytes in pregnant rats.

    abstract::Both pregnancy and cyclosporin A (CsA) are known to inhibit T-cell mediated immune response and to activate phagocytes against microbial infections as a compensatory mechanism. Pregnant women, either with organ transplantation or suffering from autoimmune diseases, are commonly managed with CsA therapy. This investiga...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1080/08923970701619760

    authors: Khan HA

    更新日期:2007-01-01 00:00:00

  • Protection of C3H/HE J mice from development of Candida albicans infection by oral administration of Juzen-taiho-to and its component, Ginseng radix: possible roles of macrophages in the host defense mechanisms.

    abstract::Protective effect of a Japanese traditional herbal medicine, Juzen-taiho-to (TJ-48), which was recently reported to augment host-mediated antifungal actions, in Candida albicans-infected mice was further studied. TJ-48, given orally once daily for 5 consecutive days in a dose of 2 g/kg after intravenous infection of C...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923979609007111

    authors: Akagawa G,Abe S,Tansho S,Uchida K,Yamaguchi H

    更新日期:1996-02-01 00:00:00

  • Modulating effect of Withania somnifera on TCA cycle enzymes and electron transport chain in azoxymethane-induced colon cancer in mice.

    abstract::The aim of the present investigation was to evaluate the efficacy of Withania somnifera on tricarboxylic acid (TCA) cycle enzymes and electron transport chain in azoxymethane-induced experimental colon cancer in mice. Azoxymethane at the dose of 15 mg/kg body weight was induced intraperitoneally once in a week for 28 ...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923970903581540

    authors: Muralikrishnan G,Amanullah S,Basha MI,Dinda AK,Shakeel F

    更新日期:2010-09-01 00:00:00

  • Anti-inflammatory, anti-angiogenic, and anti-nociceptive activities of the chloroform fraction of a methanol extract from Rosa davurica Pall. leaves in experimental animal models.

    abstract::Rosa davurica Pall. has been traditionally used to treat inflammatory diseases and tumors. Its dried leaves were extracted with absolute methanol, and the methanol extract was successively fractionated into n-hexane, chloroform, ethyl acetate, n-butanol, and aqueous fractions. Anti-angiogenic and anti-nociceptive acti...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923973.2010.491516

    authors: Jung HJ,Sa JH,Song YS,Shim TH,Park EH,Lim CJ

    更新日期:2011-03-01 00:00:00

  • Sodium valproate does not alter immune competence in mice.

    abstract::Spleen and thymus weight, delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC), contact hypersensitivity to picryl chloride, anti-sheep red blood cell hemagglutinin titers and plaque-forming cells (PFC), resistance against experimental toxoplasmosis as well as serum total and intestinal specific IgA wer...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923978909005388

    authors: Brouland JP,Perriat A,Revillard JP,Descotes J

    更新日期:1989-01-01 00:00:00

  • PMA and doxorubicin decrease viability, MTT activity and expression of CD10 marker on NALM-1 leukemic cells.

    abstract::PMA (10, 20 ng/ml) and doxorubicin (5-20 ng/ml) decreased the viability and MTT-activity of NALM-1 pre-B leukemic cells (3 days' treatment). Further, CD10 was downregulated, suggesting that PMA and doxorubicin induced differentiation of NALM-1 cells. However, PMA did not alter expression of B cell markers CD20 and of ...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1080/08923970600927520

    authors: Martin-Kleiner I,Svoboda-Beusan I,Gabrilovac J

    更新日期:2006-01-01 00:00:00

  • The interaction of immunosuppressive compounds in tandem stimulated peripheral human lymphocytes.

    abstract::We have developed an in vitro system to model the interactions of drugs used to treat transplant rejection. This system consists of stimulation of human lymphocytes with a primary mitogen (anti-T-cell receptor complex antibodies (OKT3 or wt31)) and treatment with a primary immunosuppressive drug (ISD) (Cyclosporine A ...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923979409007089

    authors: Weaver JL,Pine PS,Aszalos A

    更新日期:1994-05-01 00:00:00

  • Immunomodulatory effect of Parsley (Petroselinum crispum) essential oil on immune cells: mitogen-activated splenocytes and peritoneal macrophages.

    abstract:INTRODUCTION:Parsley (Petroselinum crispum) has been traditionally used for the treatment of allergy, autoimmune and chronic inflammatory disorders. The present study aims to investigate the suppressive effects of parsley essential oil on mouse splenocytes and macrophages cells. METHODS AND MATERIALS:Parsley essential...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.3109/08923973.2011.603338

    authors: Yousofi A,Daneshmandi S,Soleimani N,Bagheri K,Karimi MH

    更新日期:2012-04-01 00:00:00

  • Differential effects of ponesimod, a selective S1P1 receptor modulator, on blood-circulating human T cell subpopulations.

    abstract::Ponesimod, a novel selective sphingosine-1-phosphate 1 receptor modulator in the development for the treatment of autoimmune diseases, dose-dependently reduced lymphocyte counts in peripheral blood of healthy subjects. It rapidly and transiently reduced the number of circulating T and B cells, but not natural killer c...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/08923973.2014.993084

    authors: D'Ambrosio D,Steinmann J,Brossard P,Dingemanse J

    更新日期:2015-02-01 00:00:00

  • Andrographolide attenuates microglia-mediated Aβ neurotoxicity partially through inhibiting NF-κB and JNK MAPK signaling pathway.

    abstract::Neuroinflammation plays a critical role in the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease (AD). Microglial cells after activated play critical roles in development of neuroinflammation, and may accelerate the progression of AD. Andrographolide (ANDRO), a potent naturally extracte...

    journal_title:Immunopharmacology and immunotoxicology

    pub_type: 杂志文章

    doi:10.1080/08923973.2017.1344989

    authors: Yang R,Liu S,Zhou J,Bu S,Zhang J

    更新日期:2017-10-01 00:00:00