Bleomycin and FK 565 enhance the release of GM-CSF from LPS-stimulated BALB/c peritoneal macrophages.

Abstract:

:The anti-tumour antibiotic Bleomycin, the experimental immunostimulatory tripeptide FK 565, and the immunosuppressive agent Cyclosporin A were examined for their in vitro effects on the release of the haemopoietic cytokine Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) from LPS stimulated BALB/c adherent peritoneal macrophages. FK 565 and Bleomycin produced an increase in GM-CSF release indicating that these agents are capable of stimulating peritoneal macrophage populations. Cyclosporin A was found to have no effect.

authors

Blaney BA,Turk JL

doi

10.3109/08923979509016381

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

451-69

issue

3

eissn

0892-3973

issn

1532-2513

journal_volume

17

pub_type

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