Radiation-induced lung injury: impact on macrophage dysregulation and lipid alteration - a review.

abstract：BACKGROUND AND AIM:In the rat prostate, beta-adrenoreceptor (beta-AR) stimulation does not alter basal prostatic tone but may inhibit alpha1-AR-mediated, field stimulation-induced or receptor-independent contractile responses. The present study was designed to assess the alteration of basic fibroblast growth factor (bF...

journal_title：Immunopharmacology and immunotoxicology

authors： Mitropoulos D,Kyroudi-Voulgari A,Stratigea F,Perea D,Boudoulas H,Karayannacos P

更新日期：2010-03-01 00:00:00

abstract：CONTEXT:Neutrophils are the primary effector cells in the pathogenesis of transfusion-related acute lung injury or multiple organ failure after blood transfusion. OBJECTIVE:We aimed to investigate the effect of fresh (1 day preparation) and aged (42 day preparation) PRBC-derived plasma on neutrophil morphology, migrat...

journal_title：Immunopharmacology and immunotoxicology

authors： Yu C,Xu L,Chen LF,Guan YJ,Kim M,Biffl WL,Chin YE

更新日期：2013-02-01 00:00:00

abstract：:The effects of Bulnesia sarmienti (BS) aqueous extract on the cell growth of A549 cell lines were investigated. BS has strong cytotoxic activity on the A549 cell lines (IC(50); less than 100 microg/mL) in MTT assay. HPLC confirmed that BS contains catechins as major compound. Cell cycle analysis by flow cytometry indi...

journal_title：Immunopharmacology and immunotoxicology

authors： Mollah ML,Kim JO,Lee GD,Park CH,Hong JH,Kim HY,Kim KS

更新日期：2009-01-01 00:00:00

abstract：:Several studies outline the imbalance of phagocyte functions in chronic obstructive pulmonary disease (COPD). In this regard, here, we have assessed either monocyte- and polymorphonuclear cell (PMN)-mediated chemotactic, phagocytic and killing capacities or PMN-triggered metabolic pathway in a group of COPD patients b...

journal_title：Immunopharmacology and immunotoxicology

authors： Tortorella C,Ottolenghi A,Moretti AM,Jirillo E,Antonaci S

更新日期：1992-01-01 00:00:00

abstract：:Natural killer (NK) activity plays an important role in host defense against tumors, especially once augmented by immunomodulators. It is likely that the modulation of NK cells is a reflection of the environment in which they reside. The current study was undertaken to characterize the response profile of lung interst...

journal_title：Immunopharmacology and immunotoxicology

authors： Lauzon W,Lemaire I

更新日期：1991-01-01 00:00:00

abstract：:Angiogenesis, the process of new capillary formation from pre-existing vessels, has been established as an important mechanism involved in pathologic processes, such as cancer, as well as in normal physiology (Ribatti, D.; Vacca, A.; Roncali, L.; Dammacco, F. Angiogenesis under normal and pathological conditions. Haem...

journal_title：Immunopharmacology and immunotoxicology

authors： Plum SM,Vu HA,Mercer B,Fogler WE,Fortier AH

更新日期：2004-02-01 00:00:00

abstract：CONTEXT:Velvet antler (VA) is recognized as one of the most important Chinese traditional medical herbs. To date, the immunoactivity of the single component of VA is rarely studied though its compound extracts have been well analyzed. OBJECTIVE:The current study was designed to evaluate the immunomodulatory effects of...

journal_title：Immunopharmacology and immunotoxicology

authors： Zha E,Dandan L,Bai X,Zhou T,Li Y,Shenyang G,Yue X

更新日期：2016-12-01 00:00:00

abstract：:Although the development of atopy in the newborn is determined by a multitude of factors, an intense Th1 stimulus early in life could be protective by facilitating a switch away from Th2. Aimed to determine the effect of single Mycobacterium vaccae (M. vaccae) immunization to OVA-sensitized pregnant mice on IL-5 and I...

journal_title：Immunopharmacology and immunotoxicology

authors： Akkoc T,Eifan AO,Ozdemir C,Yazi D,Yesil O,Bahceciler NN,Barlan IB

更新日期：2008-01-01 00:00:00

abstract：:The aim of the present investigation was to evaluate the efficacy of Withania somnifera on tricarboxylic acid (TCA) cycle enzymes and electron transport chain in azoxymethane-induced experimental colon cancer in mice. Azoxymethane at the dose of 15 mg/kg body weight was induced intraperitoneally once in a week for 28 ...

journal_title：Immunopharmacology and immunotoxicology

authors： Muralikrishnan G,Amanullah S,Basha MI,Dinda AK,Shakeel F

更新日期：2010-09-01 00:00:00

abstract：:The immune effects of acebutolol, a beta-blocker, are investigated in various strains of mice. In 6-12 weeks old C57Bl/6 female mice, an increase in the number of immunoglobulin secreting cells is observed only at the age of 9 weeks. At that age, such an effect is seen neither in C57Bl/6 male mice nor in female mice f...

journal_title：Immunopharmacology and immunotoxicology

authors： In S,Lulé J,Fournié GJ

更新日期：1990-01-01 00:00:00

abstract：:CD69, also known as activation inducer molecule, very early activation antigen, MLR-3 and Leu-23, is a member of the natural killer (NK) cell gene complex family of signal transducing receptors. CD69 is as a type II transmembrane glycoprotein with a C-type lectin binding domain in the extracellular portion of the mole...

journal_title：Immunopharmacology and immunotoxicology

authors： Marzio R,Mauël J,Betz-Corradin S

更新日期：1999-08-01 00:00:00

abstract：:The effect of Cordyceps militaris culture broth (CMB) on melanogenesis in B16F0 melanoma cells was evaluated by measurement of the melanin concentration after 3 days of incubation. The B16F0 melanoma cells were treated with various concentrations of CMB 10-100 μg/mL and arbutin of 200 μM. Phenolic content and antioxid...

journal_title：Immunopharmacology and immunotoxicology

authors： Cha JY,Yang HJ,Park MY,Choi ST,Moon HI,Cho YS

更新日期：2011-10-13 00:00:00

abstract：:Naloxone at concentrations 10(-6) M to 10(-10) M modulated endogenous NK-activity in 11 of 14 samples of human peripheral blood lymphocytes after 18-hour incubation. The dose response usually showed two peaks, which varied with the donor. Enhancement was obtained in 6, suppression in 4, and both effects (depending on ...

journal_title：Immunopharmacology and immunotoxicology

authors： Martin-Kleiner I,Gabrilovac J

更新日期：1993-03-01 00:00:00

abstract：:Several abnormalities of the immune system have been reported in association with clinical and experimental iron overload. To dissect further such abnormalities, changes in lymphocyte subsets were evaluated in iron-loaded male Sprague-Dawley rats. The iron-loading protocol consisted of a total dose of irondextran (1.5...

journal_title：Immunopharmacology and immunotoxicology

authors： Cardier JE,Romano E,Soyano A

更新日期：1997-02-01 00:00:00

abstract：:The immunological status of lead acid battery workers with blood lead levels and urinary delta-aminolevulinic acid (ALA-U) concentrations ranging from safe to toxic levels has been examined and compared with those of non-exposed, age and sex matched controls. No differences in the serum concentrations of IgG, IgA and ...

journal_title：Immunopharmacology and immunotoxicology

authors： Queiroz ML,Perlingeiro RC,Bincoletto C,Almeida M,Cardoso MP,Dantas DC

更新日期：1994-02-01 00:00:00

abstract：:Mercuric sulfide (HgS) is a major component of cinnabar, which has been used as a sedative drug in China for more than 2000 years. Because its toxicological effects are still unclear, we attempted to verify the toxic effects of HgS, focused on liver and immune organs such as the spleen and thymus. Male ICR mice were a...

journal_title：Immunopharmacology and immunotoxicology

authors： Son HY,Lee S,Park SB,Kim MS,Choi EJ,Singh TS,Bae Y,Kwack SJ,Kang TS,Shin HI,Baek MC,Kim SH

更新日期：2010-06-01 00:00:00

abstract：:Engystol-N at the doses of 10(-4) and 10(-8) in isolated human leukocytes stimulates the superoxide anion generation by neutrophils and the cytokine(s) production by T lymphocytes. In whole blood the same concentrations of the drug produce the decrease of the superoxide anion generation of neutrophils, this inhibiting...

journal_title：Immunopharmacology and immunotoxicology

authors： Fimiani V,Cavallaro A,Ainis O,Bottari C

更新日期：2000-02-01 00:00:00

abstract：:Objective: The present study aimed to investigate whether recombinant human erythropoietin (rHuEPO) plays an immunomodulatory function by regulating the TLR4/NF-κB signaling pathway.Materials and methods: C57BL/6 mice were intraperitoneally injected with rHuEPO and, half an hour later, with 50% glycerol at the dose of...

journal_title：Immunopharmacology and immunotoxicology

authors： Zhou J,Bai Y,Jiang Y,Tarun P,Feng Y,Huang R,Fu P

更新日期：2020-02-01 00:00:00

abstract：:Disodium cromoglycate (DSCG) has been shown to inhibit the release of mediators from mast cells. In the present study, the effect of DSCG on active anaphylactic reaction was studied in mice. DSCG dose-dependently inhibited the active systemic anaphylactic reaction and serum immunoglobulin (Ig)E production induced by i...

journal_title：Immunopharmacology and immunotoxicology

authors： Seo SB,Park SJ,Park ST,Cho CC,Park BH,Lee SJ,Kim HM,Kajiuchi T,Shin TY

更新日期：2001-05-01 00:00:00

abstract：:The aim of the present study was to investigate putative mechanisms implicated in the impaired phagocytic response of spontaneously hypertensive rats (SHR)1. The effect of in vitro treatment with isoproterenol (ISO), a beta-adrenergic drug, on phagocytosis and respiratory burst by splenic macrophages (SpMø) from normo...

journal_title：Immunopharmacology and immunotoxicology

authors： Serio M,Potenza MA,Montagnani M,Mansi G,Mitolo-Chieppa D,Jirillo E

更新日期：1996-05-01 00:00:00

abstract：:We investigated immunomodulatory activity of autologous tumor cell vaccine from oral cancer patients ex vivo by lymphoproliferation assay and two color flow cytometry. Vaccine treatment lead to 10-fold higher proliferation of lymphocytes compared with the untreated controls. A significant increase in CD69(+) and HLA-D...

journal_title：Immunopharmacology and immunotoxicology

authors： Agarwal A,Mohanti BK,Das SN

更新日期：2007-01-01 00:00:00

abstract：:Snakebites in rural areas of tropical and subtropical regions are commonly treated with medicinal plants. In this report, we have studied the ability of Anacardium occidentale bark extract to neutralize enzymatic as well as pharmacological effects induced by Vipera russelii venom. The extract neutralized the viper ven...

journal_title：Immunopharmacology and immunotoxicology

authors： Ushanandini S,Nagaraju S,Nayaka SC,Kumar KH,Kemparaju K,Girish KS

更新日期：2009-01-01 00:00:00

abstract：:During the last few years, several observations outline that the impaired T lymphocyte proliferative capacity in the elderly is due to a reduced interleukin 2 (IL-2) release. To further investigate the activation process during lectin stimulation, aged peripheral blood mononuclear cells (PBMC) were stimulated with phy...

journal_title：Immunopharmacology and immunotoxicology

authors： Antonaci S,Tortorella C,Polignano A,Ottolenghi A,Jirillo E,Bonomo L

更新日期：1991-01-01 00:00:00

abstract：CONTEXT:The pentapeptide YGSRS is originated from coffee bean, while its pharmacological features have little been examined. OBJECTIVES:We investigated the effects of YGSRS on proliferation, cytokine production and CD4+ CD25+ Foxp3+ regulatory T (Treg) cell frequency of human peripheral blood mononuclear cells (PBMCs)...

journal_title：Immunopharmacology and immunotoxicology

authors： Nakamura Y,Hayakawa A,Ishizawa H,Kamei Y,Tanaka S,Onda K,Sugiyama K,Hirano T

更新日期：2015-06-01 00:00:00

abstract：:Temporary henna-based tattoos, particularly popular among western tourists holidaying in exotic places, can expose to the risk to develop allergic reactions. Although hypersensitivity to henna is extremely rare, para-phenylenediamine, which is sometimes added to henna to obtain a dark, blackish color, is a frequent co...

journal_title：Immunopharmacology and immunotoxicology

authors： Calogiuri G,Foti C,Bonamonte D,Nettis E,Muratore L,Angelini G

更新日期：2010-12-01 00:00:00

abstract：:Lymphocytes predominantly express delayed rectifier K(+)-channels (Kv1.3) in their plasma membranes, and the channels play crucial roles in the lymphocyte activation and proliferation. Since nonsteroidal anti-inflammatory drugs (NSAIDs), the most commonly used analgesic and antipyretic drugs, exert immunomodulatory ef...

journal_title：Immunopharmacology and immunotoxicology

authors： Kazama I,Maruyama Y,Murata Y

更新日期：2012-10-01 00:00:00

abstract：:The anti-tumour antibiotic Bleomycin, the experimental immunostimulatory tripeptide FK 565, and the immunosuppressive agent Cyclosporin A were examined for their in vitro effects on the release of the haemopoietic cytokine Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) from LPS stimulated BALB/c adherent pe...

journal_title：Immunopharmacology and immunotoxicology

authors： Blaney BA,Turk JL

更新日期：1995-08-01 00:00:00

abstract：:The present investigation was aimed to examine non-specific immunologic capabilities of spontaneously hypertensive rats (SHR) during the development of hypertension. In vitro phagocytosis and oxidative killing exerted by monocytes, polymorphonuclear cells (PMN) and splenic macrophages (SpM0) were evaluated in SHR at 5...

journal_title：Immunopharmacology and immunotoxicology

authors： Serio M,Potenza MA,Vulpis V,Pirrelli A,Mitolo-Chieppa D,Jirillo E

更新日期：1994-05-01 00:00:00

abstract：:We describe the case of a 42-years-old non-atopic man who developed a severe eczematous reaction in the genital area some hours after the use of a condom (Settebello-Hatù Durex) containing a retarding cream. Patch test revealed a strong allergic reaction to the retarding cream and to benzocaine and paraben mix contain...

journal_title：Immunopharmacology and immunotoxicology

authors： Foti C,Bonamonte D,Antelmi A,Conserva A,Angelini G

更新日期：2004-08-01 00:00:00

abstract：:We studied the effect of pyridoxine deficiency state on the responses of human lymphocytes to certain mitogenic factors. Deoxypyridoxine (DB6), a potent pyridoxine antagonist, considerably inhibited Bromodeoxyuridine (BrdU) incorporation into the newly synthesized DNA of lymphocytes cultured with Phytohemagglutinin (P...

journal_title：Immunopharmacology and immunotoxicology

authors： Scountzou J,Malisiovas N,Antoniadis A,Trakatellis A

更新日期：1989-01-01 00:00:00