Thymostimulin administration modulates polymorph metabolic pathway in patients with chronic obstructive pulmonary disease.

abstract：:Multiple Drug Allergy Syndrome (MDAS) is a frequent clinical condition characterized by reactions to more than one different class of antibiotics. Even if some studies have previously reported an increased rate of allergic reactions to drugs in patients with a history of antimicrobials and NSAIDs allergy, risk factors...

journal_title：Immunopharmacology and immunotoxicology

authors： Nettis E,Colanardi MC,Paola RD,Ferrannini A,Tursi A

更新日期：2001-11-01 00:00:00

abstract：:Formyl peptides released by some bacteria are powerful chemoattractants and activators of mammalian granulocytes and monocytes, acting through 7-transmembrane specific formyl peptide receptors (FPRs). Three distinct segments of the formyl peptide receptor 1 (FPR1) mRNA of Man share probabilistically significant homolo...

journal_title：Immunopharmacology and immunotoxicology

authors： Panaro MA,Acquafredda A,Sisto M,Lisi S,Calvello R,Saccia M,Maffione AB,Mitolo V

更新日期：2005-01-01 00:00:00

abstract：:This study aimed to evaluate the immunomodulatory effects of Pleurotus florida on cell-mediated immunity in Balb/c mice. Aqueous extract of P. florida was isolated, lyophilized, and stored in refrigerator until application. Forty female Balb/c mice were randomly divided into seven test and one control groups. Four gro...

journal_title：Immunopharmacology and immunotoxicology

authors： Sedaghat R,Ghazanfari T

更新日期：2011-03-01 00:00:00

abstract：CONTEXT:T regulatory (Treg) cells play an important role in the modulation of the immune response, and are implicated in the pathogenesis of autoimmune diseases. Many people is exposed to fluoride (F), mainly through drinking water. OBJECTIVE:The aim of this work was to assess the possible effect of F exposure on diff...

journal_title：Immunopharmacology and immunotoxicology

authors： Hernández-Castro B,Vigna-Pérez M,Doníz-Padilla L,Ortiz-Pérez MD,Jiménez-Capdeville E,González-Amaro R,Baranda L

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:Parsley (Petroselinum crispum) has been traditionally used for the treatment of allergy, autoimmune and chronic inflammatory disorders. The present study aims to investigate the suppressive effects of parsley essential oil on mouse splenocytes and macrophages cells. METHODS AND MATERIALS:Parsley essential...

journal_title：Immunopharmacology and immunotoxicology

authors： Yousofi A,Daneshmandi S,Soleimani N,Bagheri K,Karimi MH

更新日期：2012-04-01 00:00:00

abstract：:A competitive enzyme-linked immunosorbent assay (ELISA) with generated mouse anti-consensus interferon (CIFN) antibody was developed for quantitative determination of pegylated consensus interferon (PEG-CIFN) in rhesus monkey serum. The operational concentrations of the original assay were determined using the chessbo...

journal_title：Immunopharmacology and immunotoxicology

authors： Cao J,Du Y,Tian H,Gao XD,Yao WB

更新日期：2009-01-01 00:00:00

abstract：:We hypothesized that immunosuppression in birds that is caused by exposure to antiandrogenic chemicals occurs mainly through disruption of the development of the androgen-sensitive avian lymphoid organ, the bursa of Fabricius. Injections of 20.0 or 40.0 mug of p,p'-DDE [ethylene, 1,1-dichloro-2,2-bis(p-chlorophenyl)],...

journal_title：Immunopharmacology and immunotoxicology

authors： Quinn MJ,Summitt CL,Ottinger MA

更新日期：2006-01-01 00:00:00

abstract：:Atractylenolide I (ATL-I) is a bioactive component of Rhizoma Atractylodis macrocephalae. Although increasing evidence shows that ATL-I has an anti-inflammatory effect, the anti-inflammatory molecular mechanism of ATL-I is still unknown. In this study, we investigated the effect of ATL-I on cell viability by 3-(4, 5-D...

journal_title：Immunopharmacology and immunotoxicology

authors： Ji G,Chen R,Zheng J

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:Abnormal microglia secrete neuroinflammatory factors that play a pivotal role in neurodegenerative-disorder development. Thus, regulating abnormal microglia-activation could be a promising therapeutic strategy. The purposes of this study included investigating the effect of Petatewalide B on lipopolysacchari...

journal_title：Immunopharmacology and immunotoxicology

authors： Park SY,Choi MH,Li M,Li K,Park G,Choi YW

更新日期：2018-06-01 00:00:00

abstract：:Rosa davurica Pall. has been traditionally used to treat inflammatory diseases and tumors. Its dried leaves were extracted with absolute methanol, and the methanol extract was successively fractionated into n-hexane, chloroform, ethyl acetate, n-butanol, and aqueous fractions. Anti-angiogenic and anti-nociceptive acti...

journal_title：Immunopharmacology and immunotoxicology

authors： Jung HJ,Sa JH,Song YS,Shim TH,Park EH,Lim CJ

更新日期：2011-03-01 00:00:00

abstract：:Context: Tamoxifen (TAM) ameliorates D-galactosamine/lipopolysaccharide (Gal/LPS)-induced acute liver failure (ALF) through its antioxidative effect; thus, this study was designed to determine whether the effectiveness of TAM is related to nuclear factor-κB (NF-κB) reactivation. Materials and methods: Experimental mic...

journal_title：Immunopharmacology and immunotoxicology

authors： Liu L,Zhao Y,Lin Y,Zhang R,Luo S,Ye P,Luo M

更新日期：2019-04-01 00:00:00

abstract：:The modulatory effect of FK 506 and cyclosporin A (CsA) on the expression of inducible nitric oxide synthase (iNOS) in macrophages and mechanisms of their action were analysed. Isolated rat peritoneal macrophages were cultured for 12 or 24 h with or without lipopolysaccharide (LPS) (5 microg/ml) and in the absence or ...

journal_title：Immunopharmacology and immunotoxicology

authors： Strestíková P,Otová B,Filipec M,Masek K,Farghali H

更新日期：2001-02-01 00:00:00

abstract：:Traditionally venoms are used from thousands of years to treat pain, inflammation, and arthritis. In Ayurveda "Suchika Voron" and "Shodhona" were practiced against pain. In the present study, venom composition of the Indian honeybee Apis florea (AF), Apis dorsata (AD), and Apis cerana indica (AC) were analyzed using e...

journal_title：Immunopharmacology and immunotoxicology

authors： Nipate SS,Hurali PB,Ghaisas MM

更新日期：2015-04-01 00:00:00

abstract：:Paraquat (methyl viologen, PQ) is highly toxic to humans. Pulmonary fibrosis is the most common cause of death after PQ poisoning. However, no effective therapy is available. The current treatment dilemma and pathology suggest that we should reconsider how to treat the poisoning using other methods, such as immunizati...

journal_title：Immunopharmacology and immunotoxicology

authors： Wu Q,Xu Q,Jian X,Wang H,He X,Gao B,Wang K,Kan B

更新日期：2018-08-01 00:00:00

abstract：:In the present study, intrahepatic CD8+ lymphocyte infiltrates as well as HLA class I and CD54 (ICAM-1) antigen expression at both tissue and serum levels were evaluated in 54 untreated patients with chronic hepatitis C stratified on the basis of histological diagnosis (Chronic Persistent Hepatitis/Chronic Lobular Hep...

journal_title：Immunopharmacology and immunotoxicology

authors： Piazzolla G,Tortorella C,Fiore G,Serrone M,Caccetta L,Jirillo E,Schiraldi O,Antonaci S

更新日期：1998-08-01 00:00:00

abstract：:In the present study, we investigated the possibility that the WNT/β-catenin pathway plays a role in inflammatory responses both in an human inflammatory condition and in an in vitro inflammation model. First, we analyzed gene expression patterns of the peripheral blood cells from asthma patients compared with those f...

journal_title：Immunopharmacology and immunotoxicology

authors： Lee H,Bae S,Choi BW,Yoon Y

更新日期：2012-02-01 00:00:00

abstract：:Chief part of hemopoietic stromal cells in mediating hemopoiesis-stimulating effects of adamantylamide dipeptide (AdDP), a synthetic immunomodulatory compound, has been determined in a series of combined in vivo/in vitro studies. Indirect stimulatory effect of AdDP on proliferation of hemopoietic progenitor cells for ...

journal_title：Immunopharmacology and immunotoxicology

authors： Vacek A,Hofer M,Weiterová L,Hoferová Z,Pipalová I,Masek K

更新日期：2001-11-01 00:00:00

abstract：:Lymphocytes predominantly express delayed rectifier K(+)-channels (Kv1.3) in their plasma membranes, and the channels play crucial roles in the lymphocyte activation and proliferation. Since nonsteroidal anti-inflammatory drugs (NSAIDs), the most commonly used analgesic and antipyretic drugs, exert immunomodulatory ef...

journal_title：Immunopharmacology and immunotoxicology

authors： Kazama I,Maruyama Y,Murata Y

更新日期：2012-10-01 00:00:00

abstract：:T-2 toxin, a fungal metabolite shown previously to exert potent immunosuppressive effects, was examined for its effects on activation and interleukin 2 (IL 2) production by murine and rat splenocytes. Splenocytes (1 X 10(6) cells/well) were incubated with 1 microgram Concanavalin A (Con A) for 48 h at which time cellu...

journal_title：Immunopharmacology and immunotoxicology

authors： Holt PS,Corrier DE,DeLoach JR

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Ipomoea obscura (L.) Ker-Gawl, is a medicinal herb with indole alkaloids as an active constituent. In this study, we investigated the anti-angiogenic activity of I. obscura extract and one of its major compounds Ipobscurine-A (IPO-A). METHODS:In vivo angiogenesis was induced by injecting B16F10 melanoma cell...

journal_title：Immunopharmacology and immunotoxicology

authors： Hamsa TP,Kuttan G

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) is a chronic skin inflammatory disease characterized by disequilibrium between Th1/Th2 lymphocytes. Helicobacter pylori neutrophil-activating protein (HP-NAP) has been reported that it has the potential immunomodulatory effect able to regulate the Th1/Th2 balance. OBJECTIVE:This study...

journal_title：Immunopharmacology and immunotoxicology

authors： Guo X,Ding C,Lu J,Zhou T,Liang T,Ji Z,Xie P,Liu X,Kang Q

更新日期：2020-10-01 00:00:00

abstract：:Serum tumor necrosis factor (TNF) levels in 33 patients with inflammatory bowel disease (IBD) were measured by using a sensitive enzyme immunoassay. Four of five Crohn's diseases (CD) and nine of twenty eight ulcerative colitis (UC) had elevated levels of serum TNF. In active CD or UC, a greater fraction of patients s...

journal_title：Immunopharmacology and immunotoxicology

authors： Maeda M,Watanabe N,Neda H,Yamauchi N,Okamoto T,Sasaki H,Tsuji Y,Akiyama S,Tsuji N,Niitsu Y

更新日期：1992-01-01 00:00:00

abstract：:Thalidomide causes congenital anomalies and it is immunomodulatory. These properties could be explained by an ability to alter the orderly process of programmed cell death during embryogenesis and modulation of apoptosis of lymphoid and/or myeloid cells in the immune response. Apoptosis of lymphoid and myeloid cells w...

journal_title：Immunopharmacology and immunotoxicology

authors： Aseffa A,Dietrich MA,Shannon EJ

更新日期：1997-08-01 00:00:00

abstract：:We have previously demonstrated that the chlorphentermine (CP)1-induced impairment in lymphocyte blastogenesis involves drug-induced inhibition of an event which occurs very early during lymphocyte activation. An early event, which is associated with mitogen-induced lymphocyte activation, involves the hydrolysis of ph...

journal_title：Immunopharmacology and immunotoxicology

authors： Sauers LJ,Wierda D,Reasor MJ

更新日期：1988-01-01 00:00:00

abstract：:PMA (10, 20 ng/ml) and doxorubicin (5-20 ng/ml) decreased the viability and MTT-activity of NALM-1 pre-B leukemic cells (3 days' treatment). Further, CD10 was downregulated, suggesting that PMA and doxorubicin induced differentiation of NALM-1 cells. However, PMA did not alter expression of B cell markers CD20 and of ...

journal_title：Immunopharmacology and immunotoxicology

authors： Martin-Kleiner I,Svoboda-Beusan I,Gabrilovac J

更新日期：2006-01-01 00:00:00

abstract：:Host-parasite interactions and their outcome constitute a critical and challenging step in disease establishment in cutaneous leishmaniasis. In the present in vitro study we investigated the possible modulating effects of both sensory and autonomic neuropeptides that normally exist in human and mouse skin, on the upta...

journal_title：Immunopharmacology and immunotoxicology

authors： Ahmed AA,Wahbi AH,Nordlin K

更新日期：2001-08-01 00:00:00

abstract：CONTEXT:Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by autoreactive antibodies. Recent findings revealed the importance of innate immune responses, especially Toll-like receptors (TLRs) in the pathogenesis of SLE. OBJECTIVE:In this study, the level of TLR9 expression on peripheral...

journal_title：Immunopharmacology and immunotoxicology

authors： Mortezagholi S,Babaloo Z,Rahimzadeh P,Namdari H,Ghaedi M,Gharibdoost F,Mirzaei R,Bidad K,Salehi E

更新日期：2017-02-01 00:00:00

abstract：:Antidepressants are reported to display anti-inflammatory effects. Nitric oxide (NO), in turn, has a key role in inflammation. The objective of the present study was to evaluate the effect of amitriptyline co-administered with L-NAME (a NO synthase inhibitor) on certain parameters of acute inflammatory response in rat...

journal_title：Immunopharmacology and immunotoxicology

authors： Vismari L,Alves GJ,Muscará MN,Palermo-Neto J

更新日期：2012-08-01 00:00:00

abstract：:The guidelines for the management of urticaria in adults and children have been published in outstanding position papers. By contrast, the onset of urticaria in the elderly has not yet had a clear definition. In order to approach diagnosis and treatment in a population of elderly patients, we have performed an epidemi...

journal_title：Immunopharmacology and immunotoxicology

authors： Ventura MT,Napolitano S,Buquicchio R,Cecere R,Arsieni A

更新日期：2012-06-01 00:00:00

abstract：:Inflammatory bowel diseases are characterized by disabilities in gastrointestinal system and defects in mucosal immune system. Statins are 3-hydroxy-3-methyl glutaryl coenzyme A reductase inhibitor and are used to treat hypercholesterolemia in patients with coronary artery and atherosclerotic diseases. Recent studies ...

journal_title：Immunopharmacology and immunotoxicology

authors： Aktunc E,Kayhan B,Arasli M,Gun BD,Barut F

更新日期：2011-12-01 00:00:00