Modulating effects on CD25 and CD71 antigen expression by lectin-stimulated T lymphocytes in the elderly.

abstract：:Rosa davurica Pall. has been traditionally used to treat inflammatory diseases and tumors. Its dried leaves were extracted with absolute methanol, and the methanol extract was successively fractionated into n-hexane, chloroform, ethyl acetate, n-butanol, and aqueous fractions. Anti-angiogenic and anti-nociceptive acti...

journal_title：Immunopharmacology and immunotoxicology

authors： Jung HJ,Sa JH,Song YS,Shim TH,Park EH,Lim CJ

更新日期：2011-03-01 00:00:00

abstract：:In the present study, intrahepatic CD8+ lymphocyte infiltrates as well as HLA class I and CD54 (ICAM-1) antigen expression at both tissue and serum levels were evaluated in 54 untreated patients with chronic hepatitis C stratified on the basis of histological diagnosis (Chronic Persistent Hepatitis/Chronic Lobular Hep...

journal_title：Immunopharmacology and immunotoxicology

authors： Piazzolla G,Tortorella C,Fiore G,Serrone M,Caccetta L,Jirillo E,Schiraldi O,Antonaci S

更新日期：1998-08-01 00:00:00

abstract：:Temporary henna-based tattoos, particularly popular among western tourists holidaying in exotic places, can expose to the risk to develop allergic reactions. Although hypersensitivity to henna is extremely rare, para-phenylenediamine, which is sometimes added to henna to obtain a dark, blackish color, is a frequent co...

journal_title：Immunopharmacology and immunotoxicology

authors： Calogiuri G,Foti C,Bonamonte D,Nettis E,Muratore L,Angelini G

更新日期：2010-12-01 00:00:00

abstract：:Density of nerve fibers, axonal growth, calcitonin gene-related peptide (CGRP), and substance P, and serotonin immunoreactivity as well as concentration were all determined in a murine model of contact allergy. Female Balb/c mice were sensitized on the back with oxazolone and 6 days later challenged with the same anti...

journal_title：Immunopharmacology and immunotoxicology

authors： El-Nour H,Lundeberg L,Boman A,Beck O,Harvima IT,Theodorsson E,Nordlind K

更新日期：2005-01-01 00:00:00

abstract：:The effect of rapamycin (RAPA) on kidney function and histopathology was assessed in two strains of mice. Male C3H/HeJ mice were treated with RAPA for 4 days at doses of 25, 50, 75, and 100 mg/kg, ip and male C3H/HeJ or female Balb/cJ mice were both treated for 7 days at doses of 75, 150 and 200 mg/kg. Cyclosporine (C...

journal_title：Immunopharmacology and immunotoxicology

authors： Di Joseph JF,Sehgal SN

更新日期：1993-01-01 00:00:00

abstract：:The protective effects of baicalin (BA), a major flavone from Scutellaria radix, on acetaminophen (AP)-induced hepatotoxicity and the possible mechanism(s) of its protective action were investigated in mice. Treatment with BA (300 mg/kg, p.o.) 0.5 h after AP administration significantly prevented an increase in plasma...

journal_title：Immunopharmacology and immunotoxicology

authors： Jang SI,Kim HJ,Hwang KM,Jekal SJ,Pae HO,Choi BM,Yun YG,Kwon TO,Chung HT,Kim YC

更新日期：2003-11-01 00:00:00

abstract：:Plasma levels of human polymorphonuclear elastase (PMN-E) are considered a marker of granulocyte activation and can potentially complement the peripheral neutrophil count in laboratory and pathophysiological settings. Neutrophilic leukocytosis is a well known effect of lithium therapy, but there is no information abou...

journal_title：Immunopharmacology and immunotoxicology

authors： Capodicasa E,Russano AM,Ciurnella E,De Bellis F,Rossi R,Scuteri A,Biondi R

更新日期：2000-11-01 00:00:00

abstract：:We hypothesized that immunosuppression in birds that is caused by exposure to antiandrogenic chemicals occurs mainly through disruption of the development of the androgen-sensitive avian lymphoid organ, the bursa of Fabricius. Injections of 20.0 or 40.0 mug of p,p'-DDE [ethylene, 1,1-dichloro-2,2-bis(p-chlorophenyl)],...

journal_title：Immunopharmacology and immunotoxicology

authors： Quinn MJ,Summitt CL,Ottinger MA

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:Fingolimod (FIN) is used for multiple sclerosis treatment and has potential antiapoptotic and anti-inflammatory effects. We aimed at expanding our knowledge on various immunohistochemical markers for elucidating the possible mechanisms of action of fingolimod in the placenta and fetal lung and brain. METHOD...

journal_title：Immunopharmacology and immunotoxicology

authors： Yavuz A,Sezik M,Eris Yalcin S,Asci H,Ozmen O

更新日期：2020-12-01 00:00:00

abstract：:Heat shock protein 90 (Hsp90) is a ubiquitously expressed ATP-dependent molecular chaperone across all species that helps to the correct the folding of many proteins related to important signaling pathways. Tumor cells expressing Hsp90 have more ATP-binding affinity than normal cells. Many correlative inhibitors have ...

journal_title：Immunopharmacology and immunotoxicology

authors： Huyan T,Li Q,Dong DD,Yang H,Zhang J,Huang QS,Yin DC,Shang P

更新日期：2016-01-01 00:00:00

abstract：:Naloxone at concentrations 10(-6) M to 10(-10) M modulated endogenous NK-activity in 11 of 14 samples of human peripheral blood lymphocytes after 18-hour incubation. The dose response usually showed two peaks, which varied with the donor. Enhancement was obtained in 6, suppression in 4, and both effects (depending on ...

journal_title：Immunopharmacology and immunotoxicology

authors： Martin-Kleiner I,Gabrilovac J

更新日期：1993-03-01 00:00:00

abstract：:A soil bacterium, Klebsiella oxytoca TNM3 was found to produce a polysaccharide named AZ9 that shows suppressive effects on IgE antibody response in mice. When mice were administered with 50 to approximately 100 mg/kg AZ9 subcutaneousely for 4 consecutive days after immunization with trinitrophenyl (TNP)-keyhole limpe...

journal_title：Immunopharmacology and immunotoxicology

authors： Sugihara R,Matsumoto Y,Ohmori H

更新日期：2002-05-01 00:00:00

abstract：:We have previously demonstrated that the chlorphentermine (CP)1-induced impairment in lymphocyte blastogenesis involves drug-induced inhibition of an event which occurs very early during lymphocyte activation. An early event, which is associated with mitogen-induced lymphocyte activation, involves the hydrolysis of ph...

journal_title：Immunopharmacology and immunotoxicology

authors： Sauers LJ,Wierda D,Reasor MJ

更新日期：1988-01-01 00:00:00

abstract：:Cancer is responsible for millions of deaths each year worldwide. Pharmacological intervention with plant-derived products alone or in combination to reverse, suppress, or prevent the cancer progression plays a key role in the fight against this terrible disease. Aerva lanata is an important medicinal plant widely use...

journal_title：Immunopharmacology and immunotoxicology

authors： Siveen KS,Kuttan G

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Capsaicin is a chili pepper extract with multiple therapeutic properties including anti-liver fibrosis. However, the paucity of its underlying mechanisms limited its widely clinical application. METHODS:In the present study, carbon tetrachloride (CCl4) was used to induce liver fibrosis in mice, and transfor...

journal_title：Immunopharmacology and immunotoxicology

authors： Sheng J,Zhang B,Chen Y,Yu F

更新日期：2020-12-01 00:00:00

abstract：:We investigated immunomodulatory activity of autologous tumor cell vaccine from oral cancer patients ex vivo by lymphoproliferation assay and two color flow cytometry. Vaccine treatment lead to 10-fold higher proliferation of lymphocytes compared with the untreated controls. A significant increase in CD69(+) and HLA-D...

journal_title：Immunopharmacology and immunotoxicology

authors： Agarwal A,Mohanti BK,Das SN

更新日期：2007-01-01 00:00:00

abstract：:Objective: The present study aimed to investigate whether recombinant human erythropoietin (rHuEPO) plays an immunomodulatory function by regulating the TLR4/NF-κB signaling pathway.Materials and methods: C57BL/6 mice were intraperitoneally injected with rHuEPO and, half an hour later, with 50% glycerol at the dose of...

journal_title：Immunopharmacology and immunotoxicology

authors： Zhou J,Bai Y,Jiang Y,Tarun P,Feng Y,Huang R,Fu P

更新日期：2020-02-01 00:00:00

abstract：:The effects of anti-thyroid drug, methimazole (MMI), on haematopoiesis in inbred C57BL/6 mice were studied. The in vitro proliferative response of bone marrow (BM) cells to interleukin-3 (IL-3) was significantly increased when mice were provided with 0.1% MMI in water (w/v) ad librium for 4 to 6 weeks. Using soft agar...

journal_title：Immunopharmacology and immunotoxicology

authors： Mak NK,Lai WH,Liu WK,Leung KN,Fung MC

更新日期：1995-11-01 00:00:00

abstract：:The present investigation was aimed to examine non-specific immunologic capabilities of spontaneously hypertensive rats (SHR) during the development of hypertension. In vitro phagocytosis and oxidative killing exerted by monocytes, polymorphonuclear cells (PMN) and splenic macrophages (SpM0) were evaluated in SHR at 5...

journal_title：Immunopharmacology and immunotoxicology

authors： Serio M,Potenza MA,Vulpis V,Pirrelli A,Mitolo-Chieppa D,Jirillo E

更新日期：1994-05-01 00:00:00

abstract：:We have previously found that NK cell activity is present in rat lung lavage and inhibited by lidocaine. The purpose of this report is to characterize further the inhibition by lidocaine on NK activity. Peripheral blood lymphocytes from normal human volunteers were assayed in a four-hour 51chromium release assay in th...

journal_title：Immunopharmacology and immunotoxicology

authors： Renzi PM,Ginns LC

更新日期：1990-01-01 00:00:00

abstract：INTRODUCTION:Parsley (Petroselinum crispum) has been traditionally used for the treatment of allergy, autoimmune and chronic inflammatory disorders. The present study aims to investigate the suppressive effects of parsley essential oil on mouse splenocytes and macrophages cells. METHODS AND MATERIALS:Parsley essential...

journal_title：Immunopharmacology and immunotoxicology

authors： Yousofi A,Daneshmandi S,Soleimani N,Bagheri K,Karimi MH

更新日期：2012-04-01 00:00:00

abstract：:To probe into the mechanism of immunosuppression of FTY720, the authors study the cell cycle arrest effects of large-dose FTY720 on lymphocytes in mouse skin transplantation models and the expression of cell cycle-related factors in cell cycle regulation system in mouse skin allograft models using flow cytometry, Immu...

journal_title：Immunopharmacology and immunotoxicology

authors： Li QY,Chi YY,Liu SQ

更新日期：2008-01-01 00:00:00

abstract：:Taraxasterol, a pentacyclic-triterpene, was isolated from the Chinese medicinal herb Taraxacum officinale. In the present study, we investigated the protective effect of taraxasterol on murine model of endotoxic shock and the mechanism of its action. Mice were treated with 2.5, 5 and 10 mg/kg of taraxasterol prior to ...

journal_title：Immunopharmacology and immunotoxicology

authors： Zhang X,Xiong H,Li H,Cheng Y

更新日期：2014-02-01 00:00:00

abstract：:Thalidomide causes congenital anomalies and it is immunomodulatory. These properties could be explained by an ability to alter the orderly process of programmed cell death during embryogenesis and modulation of apoptosis of lymphoid and/or myeloid cells in the immune response. Apoptosis of lymphoid and myeloid cells w...

journal_title：Immunopharmacology and immunotoxicology

authors： Aseffa A,Dietrich MA,Shannon EJ

更新日期：1997-08-01 00:00:00

abstract：:CD69, also known as activation inducer molecule, very early activation antigen, MLR-3 and Leu-23, is a member of the natural killer (NK) cell gene complex family of signal transducing receptors. CD69 is as a type II transmembrane glycoprotein with a C-type lectin binding domain in the extracellular portion of the mole...

journal_title：Immunopharmacology and immunotoxicology

authors： Marzio R,Mauël J,Betz-Corradin S

更新日期：1999-08-01 00:00:00

abstract：:Ethanol has been recognized as an immunosuppressive agent for many years. Effects of high levels of ethanol consumption on immune functions have been extensively studied, but little is known about the effects of low levels (scuh as 5% ethanol) of ethanol consumption. Herein we report that exposure of mice to 5% ethano...

journal_title：Immunopharmacology and immunotoxicology

authors： Guo TL,Zhang LX,Chen JP,Nguyen VA,White KL Jr,Gao B

更新日期：2002-02-01 00:00:00

abstract：:Enhanced glucose utilization was observed in continuous cultures of macrophages in medium containing 4mM Quadrol, [N,N,N',N',Tetrakis(2-hydroxypropyl)ethylenediamine]. This enhancement was both time and concentration dependent. Radiolabeled 4mM Quadrol, after incubation with macrophages for 60 minutes, was shown to be...

journal_title：Immunopharmacology and immunotoxicology

authors： Bhide MV,Smith DJ

更新日期：1987-01-01 00:00:00

abstract：:The aim pf the present study was to characterize the time course of the synthesis of mRNA encoding interleukin-2 (IL-2) by peripheral blood mononuclear cells (PBMCs) isolated from nickel-allergic women and subsequently exposed to nickel sulphate in vitro. The level of this mRNA (determined by employing real-time polym...

journal_title：Immunopharmacology and immunotoxicology

authors： Falsafi-Amin H,Holst M,Lundeberg L

更新日期：2008-01-01 00:00:00

abstract：:In the present study, we investigated the possibility that the WNT/β-catenin pathway plays a role in inflammatory responses both in an human inflammatory condition and in an in vitro inflammation model. First, we analyzed gene expression patterns of the peripheral blood cells from asthma patients compared with those f...

journal_title：Immunopharmacology and immunotoxicology

authors： Lee H,Bae S,Choi BW,Yoon Y

更新日期：2012-02-01 00:00:00

abstract：:The current research was designed to determine the effect of artemether in treatment of experimental rheumatoid arthritis. Collagen-induced arthritis was induced in Lewis rats. The intramusculary administration of artemether (ART) and intraperitoneally injection of methotrexate (MTX) were started on day 25 postimmuniz...

journal_title：Immunopharmacology and immunotoxicology

authors： Cuzzocrea S,Saadat F,Di Paola R,Mirshafiey A

更新日期：2005-01-01 00:00:00