Beta-adrenoceptor responsiveness of splenic macrophages in normotensive and hypertensive rats.

abstract：:Lung cancer continues to be the leading cause of cancer deaths and more than one million lung cancer patients will die every year worldwide. Radiotherapy (RT) plays an important role in lung cancer treatment, but the side effects of RT are pneumonitis and pulmonary fibrosis. RT-induced lung injury causes damage to alv...

journal_title：Immunopharmacology and immunotoxicology

authors： S N SG,Raviraj R,Nagarajan D,Zhao W

更新日期：2019-06-01 00:00:00

abstract：:To probe into the mechanism of immunosuppression of FTY720, the authors study the cell cycle arrest effects of large-dose FTY720 on lymphocytes in mouse skin transplantation models and the expression of cell cycle-related factors in cell cycle regulation system in mouse skin allograft models using flow cytometry, Immu...

journal_title：Immunopharmacology and immunotoxicology

authors： Li QY,Chi YY,Liu SQ

更新日期：2008-01-01 00:00:00

abstract：:Carpal tunnel syndrome (CTS) is a neurological impairment caused by compression of the median nerve throughout the carpal tunnel, which consequently induces ischemia and mechanical disruption, dysfunctional axonal transport, and epidural blood flow. Most common symptoms include numbness, rather than pain, with a typic...

journal_title：Immunopharmacology and immunotoxicology

authors： Foti C,Romita P,Vestita M

更新日期：2011-12-01 00:00:00

abstract：:Arecoline, a major alkaloid of arecanut was screened to explore its modulatory influence on cell-mediated immune response in a murine model system. The in vivo and in vitro effects were evaluated at subtoxic concentrations of arecoline. Delayed type hypersensitivity (DTH) reactions to sheep red blood cells (SRBC) were...

journal_title：Immunopharmacology and immunotoxicology

authors： Selvan RS,Selvakumaran M,Rao AR

更新日期：1991-01-01 00:00:00

abstract：:Xanthohumol (XN), a prenylated chalcone present in hops (Humulus lupus L.) and beer, exhibits anti-inflammatory, antioxidant and antiproliferative activity, but has not been studied for effects on T cell-mediated immune responses. Here we demonstrate that XN has profound immunosuppressive effects on T cell proliferati...

journal_title：Immunopharmacology and immunotoxicology

authors： Gao X,Deeb D,Liu Y,Gautam S,Dulchavsky SA,Gautam SC

更新日期：2009-01-01 00:00:00

abstract：:PMA (10, 20 ng/ml) and doxorubicin (5-20 ng/ml) decreased the viability and MTT-activity of NALM-1 pre-B leukemic cells (3 days' treatment). Further, CD10 was downregulated, suggesting that PMA and doxorubicin induced differentiation of NALM-1 cells. However, PMA did not alter expression of B cell markers CD20 and of ...

journal_title：Immunopharmacology and immunotoxicology

authors： Martin-Kleiner I,Svoboda-Beusan I,Gabrilovac J

更新日期：2006-01-01 00:00:00

abstract：:Nervous and immune systems are connected by several mutual links, thus constituting a diffuse functional network in the body. In particular, neurohormones, neuropeptides, and cytokines represent the major mediators of the so-called psychoneuroendocrinoimmune axis. In this review, special emphasis is placed on certain ...

journal_title：Immunopharmacology and immunotoxicology

authors： Amati L,Selicato F,Ranieri M,Megna M,Galantino M,Miniello S,Megna G,Jirillo E

更新日期：2006-01-01 00:00:00

abstract：:Modulation of immune response to alleviate diseases has long since been of interest. Plant extracts have been widely investigated for their possible immunomodulatory properties. We have evaluated the immunomodulatory activity of aqueous extract of Rhodiola rhizome in human peripheral blood mononuclear cells (PBMCs) an...

journal_title：Immunopharmacology and immunotoxicology

authors： Mishra KP,Padwad YS,Jain M,Karan D,Ganju L,Sawhney RC

更新日期：2006-01-01 00:00:00

abstract：:Sera obtained from a group of pigs (n = 5) fed a diet amended with fumonisin containing Fusarium moniliforme culture material was used to determine the levels of Tumor Necrosis Factor-Alpha (TNF) activity by a functional bioassay utilizing the TNF sensitive WEHI 140 mouse fibrosarcoma cell line. Two pigs developed sig...

journal_title：Immunopharmacology and immunotoxicology

authors： Guzman RE,Bailey K,Casteel SW,Turk J,Rottinghaus G

更新日期：1997-05-01 00:00:00

abstract：CONTEXT:Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by autoreactive antibodies. Recent findings revealed the importance of innate immune responses, especially Toll-like receptors (TLRs) in the pathogenesis of SLE. OBJECTIVE:In this study, the level of TLR9 expression on peripheral...

journal_title：Immunopharmacology and immunotoxicology

authors： Mortezagholi S,Babaloo Z,Rahimzadeh P,Namdari H,Ghaedi M,Gharibdoost F,Mirzaei R,Bidad K,Salehi E

更新日期：2017-02-01 00:00:00

abstract：:Context: Tamoxifen (TAM) ameliorates D-galactosamine/lipopolysaccharide (Gal/LPS)-induced acute liver failure (ALF) through its antioxidative effect; thus, this study was designed to determine whether the effectiveness of TAM is related to nuclear factor-κB (NF-κB) reactivation. Materials and methods: Experimental mic...

journal_title：Immunopharmacology and immunotoxicology

authors： Liu L,Zhao Y,Lin Y,Zhang R,Luo S,Ye P,Luo M

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Capsaicin is a chili pepper extract with multiple therapeutic properties including anti-liver fibrosis. However, the paucity of its underlying mechanisms limited its widely clinical application. METHODS:In the present study, carbon tetrachloride (CCl4) was used to induce liver fibrosis in mice, and transfor...

journal_title：Immunopharmacology and immunotoxicology

authors： Sheng J,Zhang B,Chen Y,Yu F

更新日期：2020-12-01 00:00:00

abstract：:Accumulating evidence has suggested that hydrogen sulfide (H(2)S) is endogenously generated in many types of mammalian cells. Since H(2)S plays an important role in cardiovascular, central nervous and gastrointestinal systems, it is currently considered to be the third gaseous mediator. Recently, more and more attenti...

journal_title：Immunopharmacology and immunotoxicology

authors： Zhang H,Bhatia M

更新日期：2008-01-01 00:00:00

abstract：:The effects of Bulnesia sarmienti (BS) aqueous extract on the cell growth of A549 cell lines were investigated. BS has strong cytotoxic activity on the A549 cell lines (IC(50); less than 100 microg/mL) in MTT assay. HPLC confirmed that BS contains catechins as major compound. Cell cycle analysis by flow cytometry indi...

journal_title：Immunopharmacology and immunotoxicology

authors： Mollah ML,Kim JO,Lee GD,Park CH,Hong JH,Kim HY,Kim KS

更新日期：2009-01-01 00:00:00

abstract：:Paraquat (methyl viologen, PQ) is highly toxic to humans. Pulmonary fibrosis is the most common cause of death after PQ poisoning. However, no effective therapy is available. The current treatment dilemma and pathology suggest that we should reconsider how to treat the poisoning using other methods, such as immunizati...

journal_title：Immunopharmacology and immunotoxicology

authors： Wu Q,Xu Q,Jian X,Wang H,He X,Gao B,Wang K,Kan B

更新日期：2018-08-01 00:00:00

abstract：:A soil bacterium, Klebsiella oxytoca TNM3 was found to produce a polysaccharide named AZ9 that shows suppressive effects on IgE antibody response in mice. When mice were administered with 50 to approximately 100 mg/kg AZ9 subcutaneousely for 4 consecutive days after immunization with trinitrophenyl (TNP)-keyhole limpe...

journal_title：Immunopharmacology and immunotoxicology

authors： Sugihara R,Matsumoto Y,Ohmori H

更新日期：2002-05-01 00:00:00

abstract：:The induction of T-cell responses involves the recognition of extrinsic antigens in association with antigens of the major histocompatibility complex (MHC). The present results demonstrate that the lateralized control exerted by the brain neocortex on T-cell activities extends to the expression of MHC antigens, yet di...

journal_title：Immunopharmacology and immunotoxicology

authors： Renoux G,Renoux M,Bizière K

更新日期：1988-01-01 00:00:00

abstract：:The current research was designed to determine the effect of artemether in treatment of experimental rheumatoid arthritis. Collagen-induced arthritis was induced in Lewis rats. The intramusculary administration of artemether (ART) and intraperitoneally injection of methotrexate (MTX) were started on day 25 postimmuniz...

journal_title：Immunopharmacology and immunotoxicology

authors： Cuzzocrea S,Saadat F,Di Paola R,Mirshafiey A

更新日期：2005-01-01 00:00:00

abstract：:In this study we investigated the ability of GM-1/P, a calcium mediated processed form of monosialoganglioside GM-1, of in vivo augmenting mouse T and B-lymphocyte blastogenesis induced by mitogens. We have also determined its effect on IL-2 responsiveness by analyzing the induction of the expression of IL-2 receptor ...

journal_title：Immunopharmacology and immunotoxicology

authors： Giuffrida A,Morrone S,Gismondi A,Santoni G,Punturieri A,Velotti F,Cavallo G,Tubaro E,Piccoli M,Frati L

更新日期：1990-01-01 00:00:00

abstract：:Myasthenia gravis is an autoimmune disease in which antibodies are produced against one's acetylcholine receptors, resulting in complement-mediated membrane destruction and internalization of antibody-receptor complexes. Symptoms range from weakening of extraocular muscles to severe impairment of movement and breathin...

journal_title：Immunopharmacology and immunotoxicology

authors： Hinman CL,Stevens-Truss R

更新日期：1998-05-01 00:00:00

abstract：:The anti-cancer activity of saponins and phenolic compounds present in green tea was previously reported. However, the immunomodulatory and adjuvanticity activity of tea saponin has never been studied. In this study, we investigated the immunomodulatory effect of tea saponin in T-lymphocytes and EL4 cells via regulati...

journal_title：Immunopharmacology and immunotoxicology

authors： Bhardwaj J,Chaudhary N,Seo HJ,Kim MY,Shin TS,Kim JD

更新日期：2014-06-01 00:00:00

abstract：:We describe the case of a 42-years-old non-atopic man who developed a severe eczematous reaction in the genital area some hours after the use of a condom (Settebello-Hatù Durex) containing a retarding cream. Patch test revealed a strong allergic reaction to the retarding cream and to benzocaine and paraben mix contain...

journal_title：Immunopharmacology and immunotoxicology

authors： Foti C,Bonamonte D,Antelmi A,Conserva A,Angelini G

更新日期：2004-08-01 00:00:00

abstract：:Reynoutria elliptica has been used in traditional Korean medicine to promote blood circulation, relieve pain, increase dieresis, and alleviate respiratory problems, through as yet undefined mechanisms. We set out to determine whether the anti-inflammatory effects of this plant are linked with its ability to suppress m...

journal_title：Immunopharmacology and immunotoxicology

authors： Lee G,Choi TW,Kim C,Nam D,Lee SG,Jang HJ,Lee JH,Um JY,Jung SH,Shim BS,Ahn KS,Ahn KS

更新日期：2012-06-01 00:00:00

abstract：:Temporary henna-based tattoos, particularly popular among western tourists holidaying in exotic places, can expose to the risk to develop allergic reactions. Although hypersensitivity to henna is extremely rare, para-phenylenediamine, which is sometimes added to henna to obtain a dark, blackish color, is a frequent co...

journal_title：Immunopharmacology and immunotoxicology

authors： Calogiuri G,Foti C,Bonamonte D,Nettis E,Muratore L,Angelini G

更新日期：2010-12-01 00:00:00

abstract：:Several abnormalities of the immune system have been reported in association with clinical and experimental iron overload. To dissect further such abnormalities, changes in lymphocyte subsets were evaluated in iron-loaded male Sprague-Dawley rats. The iron-loading protocol consisted of a total dose of irondextran (1.5...

journal_title：Immunopharmacology and immunotoxicology

authors： Cardier JE,Romano E,Soyano A

更新日期：1997-02-01 00:00:00

abstract：:In the present study, we investigated the possibility that the WNT/β-catenin pathway plays a role in inflammatory responses both in an human inflammatory condition and in an in vitro inflammation model. First, we analyzed gene expression patterns of the peripheral blood cells from asthma patients compared with those f...

journal_title：Immunopharmacology and immunotoxicology

authors： Lee H,Bae S,Choi BW,Yoon Y

更新日期：2012-02-01 00:00:00

abstract：:We previously showed that formation of pulmonary granulomas in mice in response to a mycobacterial glycolipid, trehalose 6,6'-dimycolate (TDM) is due to the action of TNF-α and not of IFN-γ. However, the mechanisms of formation and maintenance of pulmonary granulomas are not yet clear. The purpose of the present study...

journal_title：Immunopharmacology and immunotoxicology

authors： Saitoh T,Yano I,Kumazawa Y,Takimoto H

更新日期：2012-10-01 00:00:00

abstract：UNLABELLED:The angiotensin (Ang)-converting enzyme (ACE) insertion/deletion (I/D) polymorphism determines Ang II levels, but its relationship with lupus nephritis (LN) in different populations is controversial. OBJECTIVE:To describe the allelic and genotypic distribution of the I/D polymorphism in Mexican mestizos wit...

journal_title：Immunopharmacology and immunotoxicology

authors： Topete-Reyes JF,Soto-Vargas J,Morán-Moguel MC,Dávalos-Rodríguez IP,Chávez-González EL,García-de la Torre I,Parra-Michel R,Medina-Pérez M,Jalomo-Martínez B,Salazar-Páramo M

更新日期：2013-02-01 00:00:00

abstract：:Objective: The present study aimed to investigate whether recombinant human erythropoietin (rHuEPO) plays an immunomodulatory function by regulating the TLR4/NF-κB signaling pathway.Materials and methods: C57BL/6 mice were intraperitoneally injected with rHuEPO and, half an hour later, with 50% glycerol at the dose of...

journal_title：Immunopharmacology and immunotoxicology

authors： Zhou J,Bai Y,Jiang Y,Tarun P,Feng Y,Huang R,Fu P

更新日期：2020-02-01 00:00:00

abstract：:Formyl peptides released by some bacteria are powerful chemoattractants and activators of mammalian granulocytes and monocytes, acting through 7-transmembrane specific formyl peptide receptors (FPRs). Three distinct segments of the formyl peptide receptor 1 (FPR1) mRNA of Man share probabilistically significant homolo...

journal_title：Immunopharmacology and immunotoxicology

authors： Panaro MA,Acquafredda A,Sisto M,Lisi S,Calvello R,Saccia M,Maffione AB,Mitolo V

更新日期：2005-01-01 00:00:00