Inhibitory effect of deoxypyridoxine on the action of certain mitogenic factors.

abstract：:Formyl peptides are oligopeptides released by Gram-negative bacteria. So far, specific formyl peptide receptors (FPRs) have been described in mammals only. FPRs are seven-transmembrane G-coupled molecules and make up a relatively homogeneous group, although exhibiting different levels of affinity for the ligands. We e...

journal_title：Immunopharmacology and immunotoxicology

authors： Panaro MA,Acquafredda A,Sisto M,Lisi S,Calvello R,Mitolo CI,Cianciulli A,Mitolo V

更新日期：2007-01-01 00:00:00

abstract：:A polymerase chain reaction was devised to simultaneously detect repeated insertion sequences and the pertussis toxin promoter gene for the diagnostic identification of Bordetella pertussis, B. parapertussis, and B. bronchiseptica. The sensitivity of this method was sufficient to detect one B. pertussis organism using...

journal_title：Immunopharmacology and immunotoxicology

authors： Furuya D,Yagihashi A,Endoh T,Uehara N,Fujii N,Chiba S,Watanabe N

更新日期：1999-02-01 00:00:00

abstract：:PMA (10, 20 ng/ml) and doxorubicin (5-20 ng/ml) decreased the viability and MTT-activity of NALM-1 pre-B leukemic cells (3 days' treatment). Further, CD10 was downregulated, suggesting that PMA and doxorubicin induced differentiation of NALM-1 cells. However, PMA did not alter expression of B cell markers CD20 and of ...

journal_title：Immunopharmacology and immunotoxicology

authors： Martin-Kleiner I,Svoboda-Beusan I,Gabrilovac J

更新日期：2006-01-01 00:00:00

abstract：:The Scrophularia buergeriana (SB) has long been used to treat various diseases an account of its antimicrobial and anti-virus activity. However, it is unclear how SB regulates the immune responses. This study investigated the effect of SB on the production of cytokines in a human T-cell line, MOLT-4 cells, and mouse p...

journal_title：Immunopharmacology and immunotoxicology

authors： Kim SJ,Park JS,Myung NY,Moon PD,Choi IY,An HJ,Kim NH,Na HJ,Kim DH,Kim MC,An NH,Kim IK,Lee JY,Jeong HJ,Um JY,Kim HM,Hong SH

更新日期：2009-06-01 00:00:00

abstract：:Several abnormalities of the immune system have been reported in association with clinical and experimental iron overload. To dissect further such abnormalities, changes in lymphocyte subsets were evaluated in iron-loaded male Sprague-Dawley rats. The iron-loading protocol consisted of a total dose of irondextran (1.5...

journal_title：Immunopharmacology and immunotoxicology

authors： Cardier JE,Romano E,Soyano A

更新日期：1997-02-01 00:00:00

abstract：:Neuroinflammation plays a critical role in the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease (AD). Microglial cells after activated play critical roles in development of neuroinflammation, and may accelerate the progression of AD. Andrographolide (ANDRO), a potent naturally extracte...

journal_title：Immunopharmacology and immunotoxicology

authors： Yang R,Liu S,Zhou J,Bu S,Zhang J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Tacrolimus causes post-transplant diabetes mellitus, however the pathogenetic mechanisms remain controversial. In this study we probed into the mechanisms of tacrolimus-induced diabetes mellitus in rats. METHODS:Glucose levels were determined on whole blood samples using a glucose oxidase method. Levels of ...

journal_title：Immunopharmacology and immunotoxicology

authors： Li QY,Li F,Sun JH,Chi YY,Yin HS,Liu SQ,Mei YH

更新日期：2009-01-01 00:00:00

abstract：:The effects of Bulnesia sarmienti (BS) aqueous extract on the cell growth of A549 cell lines were investigated. BS has strong cytotoxic activity on the A549 cell lines (IC(50); less than 100 microg/mL) in MTT assay. HPLC confirmed that BS contains catechins as major compound. Cell cycle analysis by flow cytometry indi...

journal_title：Immunopharmacology and immunotoxicology

authors： Mollah ML,Kim JO,Lee GD,Park CH,Hong JH,Kim HY,Kim KS

更新日期：2009-01-01 00:00:00

abstract：CONTEXT:Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by autoreactive antibodies. Recent findings revealed the importance of innate immune responses, especially Toll-like receptors (TLRs) in the pathogenesis of SLE. OBJECTIVE:In this study, the level of TLR9 expression on peripheral...

journal_title：Immunopharmacology and immunotoxicology

authors： Mortezagholi S,Babaloo Z,Rahimzadeh P,Namdari H,Ghaedi M,Gharibdoost F,Mirzaei R,Bidad K,Salehi E

更新日期：2017-02-01 00:00:00

abstract：:Carboxymethylglucan (CMG) in two different degrees of substitution of carboxymethyl groups (0.56 and 0.89) was administered to cyclophosphamide (CY) treated (200 mg/kg) C57B1/6 mice in three doses (10, 50, and 100 mg/kg) 24 h after CY. The influence of CMG administration on the cell suppression caused by CY was observ...

journal_title：Immunopharmacology and immunotoxicology

authors： Wagnerová J,Lísková A,Navarová J,Kristofová A,Trnovec T,Ferencík M

更新日期：1993-03-01 00:00:00

abstract：:Rosa davurica Pall. has been traditionally used to treat inflammatory diseases and tumors. Its dried leaves were extracted with absolute methanol, and the methanol extract was successively fractionated into n-hexane, chloroform, ethyl acetate, n-butanol, and aqueous fractions. Anti-angiogenic and anti-nociceptive acti...

journal_title：Immunopharmacology and immunotoxicology

authors： Jung HJ,Sa JH,Song YS,Shim TH,Park EH,Lim CJ

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To establish the clearance of cervical human papillomavirus (HPV) infection following postoperative immunotherapy with inosine pranobex in women receiving surgical treatment of established high-grade squamous intraepithelial lesion (HSIL) of the uterine cervix. MATERIALS AND METHODS:Over the six-year study p...

journal_title：Immunopharmacology and immunotoxicology

authors： Kovachev SM

更新日期：2020-08-01 00:00:00

abstract：:We examined the effects of interferon (IFN)beta-1a on interleukin (IL)-12p70 and IL-10 secretion in 27 Relapsing Remitting Multiple Sclerosis (RRMS) patients, divided in responders and non-responders. In responders, IFNbeta-1a does not change the IL-12p70 concentrations, but it leads to a remarkable increase in the IL...

journal_title：Immunopharmacology and immunotoxicology

authors： Carrieri PB,Ladogana P,Di Spigna G,de Leva MF,Petracca M,Montella S,Buonavolontà L,Florio C,Postiglione L

更新日期：2008-01-01 00:00:00

abstract：:Paraquat (methyl viologen, PQ) is highly toxic to humans. Pulmonary fibrosis is the most common cause of death after PQ poisoning. However, no effective therapy is available. The current treatment dilemma and pathology suggest that we should reconsider how to treat the poisoning using other methods, such as immunizati...

journal_title：Immunopharmacology and immunotoxicology

authors： Wu Q,Xu Q,Jian X,Wang H,He X,Gao B,Wang K,Kan B

更新日期：2018-08-01 00:00:00

abstract：:The objective of the current study was to assess the effects of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) along with their simultaneous application on proliferation and pluripotency genes of murine adipose tissue-derived mesenchymal stem cells (AT-MSCs). The proliferation, doubling time (DT), colony-for...

journal_title：Immunopharmacology and immunotoxicology

authors： Mohammadpour H,Pourfathollah AA,Nikougoftar Zarif M,Hashemi SM

更新日期：2016-01-01 00:00:00

abstract：:A human THP-1 monocyte cell line culture system has been utilized to observe the effect of granulocyte macrophage colony stimulating factor (GM-CSF) supplementation with lipopolysaccharide (LPS) of oral microorganisms to stimulate monocyte/macrophage functional activity. LPS of oral microorganisms, Fusobacterium nucle...

journal_title：Immunopharmacology and immunotoxicology

authors： Baqui AA,Meiller TF,Turng BF,Kelley JI,Falkler WA Jr

更新日期：1998-11-01 00:00:00

abstract：INTRODUCTION AND AIMS:N-Acetyl-β-D-glucosaminidase (NAG), a marker of renal tubular dysfunction, is increased in patients with lupus nephritis. In addition to the toxic effects of proteinuria, patients with lupus nephritis may exhibit other factors that contribute to tubular dysfunction, such as pathogenic antitubular ...

journal_title：Immunopharmacology and immunotoxicology

authors： Gluhovschi C,Velciov S,Kaycsa A,Gluhovschi G,Petrica L,Marian R,Bozdog G,Gadalean F,Bob F,Cioca D,Vernic C

更新日期：2012-02-01 00:00:00

abstract：:Arecoline, a major alkaloid of arecanut was screened to explore its modulatory influence on cell-mediated immune response in a murine model system. The in vivo and in vitro effects were evaluated at subtoxic concentrations of arecoline. Delayed type hypersensitivity (DTH) reactions to sheep red blood cells (SRBC) were...

journal_title：Immunopharmacology and immunotoxicology

authors： Selvan RS,Selvakumaran M,Rao AR

更新日期：1991-01-01 00:00:00

abstract：:Immunostimulants known to initiate cytokine production were found to inhibit processes of microsomal drug oxidation but to activate arylamine N-acetylation. The present study investigated the effects of immunstimulating doses of rat interferon-gamma (IFN gamma, 670,000 units ip) and streptolysin O (SLO, 100 HU/kg iv f...

journal_title：Immunopharmacology and immunotoxicology

authors： Walter R,Siegmund W,Scheuch E

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND AND AIM:To probe into the effects of different doses of FK506 on endocrine function of pancreatic islets in Wistar rats. METHODS:Wistar rats were randomly divide into control group A (0mg/kg/d) and experimental group B (1mg/kg/d), C (3mg/kg/d), D (10mg/kg/d) treated with FK506. In an intraperitoneal glucose...

journal_title：Immunopharmacology and immunotoxicology

authors： Li F,Li Q

更新日期：2010-06-01 00:00:00

abstract：:The aim of this study was to investigate the anti-endotoxin effects of sinomenine, fangchinoline, stachydrine, chuanxionggzine, oxymartrine and evodiamine alkaloids commonly found in Chinese herbal medicines. Porcine endothelial cells were challenged with 1 μg LPS/ml for 3 h and then treated with one of the six alkalo...

journal_title：Immunopharmacology and immunotoxicology

authors： Hu Y,He K,Zhu H

更新日期：2015-06-01 00:00:00

abstract：:Enhanced glucose utilization was observed in continuous cultures of macrophages in medium containing 4mM Quadrol, [N,N,N',N',Tetrakis(2-hydroxypropyl)ethylenediamine]. This enhancement was both time and concentration dependent. Radiolabeled 4mM Quadrol, after incubation with macrophages for 60 minutes, was shown to be...

journal_title：Immunopharmacology and immunotoxicology

authors： Bhide MV,Smith DJ

更新日期：1987-01-01 00:00:00

abstract：:Plasma levels of human polymorphonuclear elastase (PMN-E) are considered a marker of granulocyte activation and can potentially complement the peripheral neutrophil count in laboratory and pathophysiological settings. Neutrophilic leukocytosis is a well known effect of lithium therapy, but there is no information abou...

journal_title：Immunopharmacology and immunotoxicology

authors： Capodicasa E,Russano AM,Ciurnella E,De Bellis F,Rossi R,Scuteri A,Biondi R

更新日期：2000-11-01 00:00:00

abstract：CONTEXT:Serum IgA suppresses immune responses when exposed to antigens recognized by the antibody; however, the underlying mechanism remains unclear. OBJECTIVE:We herein clarified the relationships between changes in antigen distribution and antigen-dependent B cell activation in the presence or absence of IgA against...

journal_title：Immunopharmacology and immunotoxicology

authors： Yamaki K,Yoshino S

更新日期：2016-01-01 00:00:00

abstract：:Nervous and immune systems are connected by several mutual links, thus constituting a diffuse functional network in the body. In particular, neurohormones, neuropeptides, and cytokines represent the major mediators of the so-called psychoneuroendocrinoimmune axis. In this review, special emphasis is placed on certain ...

journal_title：Immunopharmacology and immunotoxicology

authors： Amati L,Selicato F,Ranieri M,Megna M,Galantino M,Miniello S,Megna G,Jirillo E

更新日期：2006-01-01 00:00:00

abstract：CONTEXT:Disease Modifying Anti-Rheumatic Drugs (DMARDs) are aimed to interfere with rheumatoid arthritis (RA) progression and reduce the joint damage; however, not all patients respond alike. Killer-cell immunoglobulin-like receptors (KIR) and their ligands, human leucocyte antigen class I (HLA-I), have been associated...

journal_title：Immunopharmacology and immunotoxicology

authors： Velarde-de la Cruz EE,Sánchez-Hernández PE,Muñoz-Valle JF,Palafox-Sánchez CA,Ramírez-de Los Santos S,Graciano-Machuca O,García-Iglesias T,Montoya-Buelna M,Ramírez-Dueñas MG

更新日期：2016-08-01 00:00:00

abstract：:Tubeimoside-1 (TBMS1) is one of the important components in Bolbostemma paniculatum (Maxim.) Franque. In the study, its immunosuppressive effects on murine T lymphocyte responses were evaluated in vitro and in vivo. The data showed that TBMS1 inhibited ConA-induced T lymphocyte proliferation, decreased the ratio of CD...

journal_title：Immunopharmacology and immunotoxicology

authors： Huang Y,Ren M,Xiong Y,Wang T,Chen H,Deng X,Lu J

更新日期：2015-01-01 00:00:00

abstract：:Spleen and thymus weight, delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC), contact hypersensitivity to picryl chloride, anti-sheep red blood cell hemagglutinin titers and plaque-forming cells (PFC), resistance against experimental toxoplasmosis as well as serum total and intestinal specific IgA wer...

journal_title：Immunopharmacology and immunotoxicology

authors： Brouland JP,Perriat A,Revillard JP,Descotes J

更新日期：1989-01-01 00:00:00

abstract：:The rate of collagen deposition in implanted polytetrafluoroethylene (PTFE) tubing in non-diabetic and streptozotocin-induced (STZ) diabetic mice was measured during 14 days post-wounding. At the time of implantation, test groups received injections of either Quadrol [N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine...

journal_title：Immunopharmacology and immunotoxicology

authors： Bhide MV,Dunphy MJ,Mirkopulos N,Smith DJ

更新日期：1988-01-01 00:00:00

abstract：:Lymphocyte proliferation assays are commonly used to quantify the effects of immunosuppressive drugs in animal models, but the influence of anesthetic agents on those assays is not well understood. We used a whole blood proliferation assay to compare lymphocyte proliferation in blood drawn from normal male Lewis rats ...

journal_title：Immunopharmacology and immunotoxicology

authors： Gummert JF,Otto G,Barten MJ,Morris RE

更新日期：1999-05-01 00:00:00