IgA directly inhibits antigen-dependent B cell activation following distinctive distribution of the antigen in mice.

abstract：:Sexual assault was a ubiquitous and serious problem in our society. The world's care centers and forensic associations, which were at the forefront of scientific research in sexual assaults, discussed the role of the Forensic Nursing in their early diagnosis and their prevention, but little has been written in literat...

journal_title：Immunopharmacology and immunotoxicology

authors： Vitale E

更新日期：2012-04-01 00:00:00

abstract：:3'-azido-3'-deoxythymidine (AZT) was administered orally to 8 AIDS patients at a dose of 100 mg every 6 hours for 14 days. On days 8 - 14 the patients were also given 1 g inosine-pranobex (INPX) every 6 hours. On day 7, while the subjects were taking AZT alone and on day 14 while they were receiving AZT + INPX, blood ...

journal_title：Immunopharmacology and immunotoxicology

authors： De Simone C,Ferrazzi M,Bitonti F,Falciano M,Tzantzoglou S,Delia S,Sorice F

更新日期：1988-01-01 00:00:00

abstract：:Chief part of hemopoietic stromal cells in mediating hemopoiesis-stimulating effects of adamantylamide dipeptide (AdDP), a synthetic immunomodulatory compound, has been determined in a series of combined in vivo/in vitro studies. Indirect stimulatory effect of AdDP on proliferation of hemopoietic progenitor cells for ...

journal_title：Immunopharmacology and immunotoxicology

authors： Vacek A,Hofer M,Weiterová L,Hoferová Z,Pipalová I,Masek K

更新日期：2001-11-01 00:00:00

abstract：:Myasthenia gravis is an autoimmune disease in which antibodies are produced against one's acetylcholine receptors, resulting in complement-mediated membrane destruction and internalization of antibody-receptor complexes. Symptoms range from weakening of extraocular muscles to severe impairment of movement and breathin...

journal_title：Immunopharmacology and immunotoxicology

authors： Hinman CL,Stevens-Truss R

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND AIM:In the rat prostate, beta-adrenoreceptor (beta-AR) stimulation does not alter basal prostatic tone but may inhibit alpha1-AR-mediated, field stimulation-induced or receptor-independent contractile responses. The present study was designed to assess the alteration of basic fibroblast growth factor (bF...

journal_title：Immunopharmacology and immunotoxicology

authors： Mitropoulos D,Kyroudi-Voulgari A,Stratigea F,Perea D,Boudoulas H,Karayannacos P

更新日期：2010-03-01 00:00:00

abstract：:Neuroinflammation plays a critical role in the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease (AD). Microglial cells after activated play critical roles in development of neuroinflammation, and may accelerate the progression of AD. Andrographolide (ANDRO), a potent naturally extracte...

journal_title：Immunopharmacology and immunotoxicology

authors： Yang R,Liu S,Zhou J,Bu S,Zhang J

更新日期：2017-10-01 00:00:00

abstract：:The effects of Bulnesia sarmienti (BS) aqueous extract on the cell growth of A549 cell lines were investigated. BS has strong cytotoxic activity on the A549 cell lines (IC(50); less than 100 microg/mL) in MTT assay. HPLC confirmed that BS contains catechins as major compound. Cell cycle analysis by flow cytometry indi...

journal_title：Immunopharmacology and immunotoxicology

authors： Mollah ML,Kim JO,Lee GD,Park CH,Hong JH,Kim HY,Kim KS

更新日期：2009-01-01 00:00:00

abstract：:Spleen and thymus weight, delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC), contact hypersensitivity to picryl chloride, anti-sheep red blood cell hemagglutinin titers and plaque-forming cells (PFC), resistance against experimental toxoplasmosis as well as serum total and intestinal specific IgA wer...

journal_title：Immunopharmacology and immunotoxicology

authors： Brouland JP,Perriat A,Revillard JP,Descotes J

更新日期：1989-01-01 00:00:00

abstract：:Increased numbers of myeloid-derived suppressor cells (MDSCs) are often observed in various pathological and physiological conditions. However, the interactions between neurotransmitters and MDSCs have not been elucidated. In this study, we studied whether norepinephrine (NE), a neurotransmitter, could affect the diff...

journal_title：Immunopharmacology and immunotoxicology

authors： Liu Y,Wei J,Guo G,Zhou J

更新日期：2015-01-01 00:00:00

abstract：:Various cells are associated with the integrated stress response (ISR) that leads to translation arrest via phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Pathogenic insults or nutritional imbalance in the mucosal tissues including the intestinal, airway, and genitourinary epitheli...

journal_title：Immunopharmacology and immunotoxicology

authors： Park SH,Moon Y

更新日期：2013-04-01 00:00:00

abstract：:To investigate the role of CD4(+) T cells in neurotrophin production following toluene exposure, male C3H mice were exposed to filtered air (control) or 9 ppm of toluene in a nose-only exposure chamber for 30 min on 3 consecutive days followed by weekly sessions for 4 weeks. All the mice were immunized with ovalbumin ...

journal_title：Immunopharmacology and immunotoxicology

authors： Fujimaki H,Win-Shwe TT,Yamamoto S,Nakajima D,Goto S

更新日期：2009-01-01 00:00:00

abstract：:Luminol-enhanced chemiluminescence assay was used to detect the surface expression and the consequent activation of receptors (FcRI and FcRII) of murine macrophages (M phi s). When murine IgG2a was used for the specific detection of FcRI and IgG2b for FcRII, a newly established procedure enabled us to detect the activ...

journal_title：Immunopharmacology and immunotoxicology

authors： Majima T,Itoh K,Yatsu J,Yoshie O,Ishida N

更新日期：1989-01-01 00:00:00

abstract：:Natural killer (NK) activity plays an important role in host defense against tumors, especially once augmented by immunomodulators. It is likely that the modulation of NK cells is a reflection of the environment in which they reside. The current study was undertaken to characterize the response profile of lung interst...

journal_title：Immunopharmacology and immunotoxicology

authors： Lauzon W,Lemaire I

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of ginsenoside metabolite compound K (CK) on adjuvant-induced arthritis (AA) rats and the partial mechanisms focused on the function of immunocyte (B cell and macrophage) and effectors' cell (fibroblast-like synoviocyte, FLS). METHODS:Animals were divided randomly into nine groups ...

journal_title：Immunopharmacology and immunotoxicology

authors： Wu H,Chen J,Wang Q,Jia X,Song S,Yuan P,Liu K,Liu L,Zhang Y,Zhou A,Wei W

更新日期：2014-04-01 00:00:00

abstract：:Aberrant expression of apoptosis-related genes, including the "cell death suppressor gene" bcl-2, may play an important pathogenetic role in cancer and autoimmune diseases, In vivo upregulation of bcl-2 mRNA in synovial lining cells of patients with rheumatoid arthritis but not in patients with osteoarthritis has been...

journal_title：Immunopharmacology and immunotoxicology

authors： Sfikakis PP,Dimopoulos MA,Souliotis VL,Charalambopoulos D,Mavrikakis M,Panayiotidis P

更新日期：1998-02-01 00:00:00

abstract：:Paraquat (methyl viologen, PQ) is highly toxic to humans. Pulmonary fibrosis is the most common cause of death after PQ poisoning. However, no effective therapy is available. The current treatment dilemma and pathology suggest that we should reconsider how to treat the poisoning using other methods, such as immunizati...

journal_title：Immunopharmacology and immunotoxicology

authors： Wu Q,Xu Q,Jian X,Wang H,He X,Gao B,Wang K,Kan B

更新日期：2018-08-01 00:00:00

abstract：:The application of heat shock to different types of cells is known to cause multiple biochemical and metabolic changes. The predominant event though is an increased synthesis and expression of a family of proteins, the heat-shock proteins (Hsp). Some of these proteins are currently considered to be involved in the sig...

journal_title：Immunopharmacology and immunotoxicology

authors： Liossis SN,Tsokos GC

更新日期：1997-11-01 00:00:00

abstract：:We conducted a comparative study of NK1.1+ cells in spleen and bone marrow and the effects of administration of M-CSF on them. Administration of M-CSF to mice increased the number of NK1.1+ cells in spleen but not in bone marrow. The NK1.1+ cells in spleen (Spl-NK1.1) and bone marrow (BM-NK1.1) were purified by magnet...

journal_title：Immunopharmacology and immunotoxicology

authors： Sakurai T,Misawa E,Yamada M,Hayasawa H,Motoyoshi K

更新日期：2002-11-01 00:00:00

abstract：:Traditionally venoms are used from thousands of years to treat pain, inflammation, and arthritis. In Ayurveda "Suchika Voron" and "Shodhona" were practiced against pain. In the present study, venom composition of the Indian honeybee Apis florea (AF), Apis dorsata (AD), and Apis cerana indica (AC) were analyzed using e...

journal_title：Immunopharmacology and immunotoxicology

authors： Nipate SS,Hurali PB,Ghaisas MM

更新日期：2015-04-01 00:00:00

abstract：:A human hepatoma cell line, Hep G2 cells are reliable for the study of alcohol-induced hepatotoxicity. In this study, we investigated the effect of an aqueous extract of Polygala tenuifolia WILLDENOW (Polygalaceae) roots (PTAE) on ethanol (EtOH)-induced cytotoxicity in Hep G2 cells. PTAE (0.01-1 microg/ml) dose-depend...

journal_title：Immunopharmacology and immunotoxicology

authors： Koo HN,Jeong HJ,Kim KR,Kim JC,Kim KS,Kang BK,Kim HM,Kim JJ

更新日期：2000-08-01 00:00:00

abstract：:In the present study, we introduce a new class of organometallic compound, the Biphosphinic Palladacycle Complex [Pd (C2, N-S(-)(dmpa)(dppf)] Cl (BPC), as an angiotensin-I converting-enzyme inhibitor (ACEI) with hematological regulation properties. When BPC was assayed as a competitive inhibitor over the hydrolysis of...

journal_title：Immunopharmacology and immunotoxicology

authors： Caires AC,Oliveira CR,Smith MC,Hemerly JP,Juliano MA,Bincoletto C

更新日期：2004-01-01 00:00:00

abstract：:The aim pf the present study was to characterize the time course of the synthesis of mRNA encoding interleukin-2 (IL-2) by peripheral blood mononuclear cells (PBMCs) isolated from nickel-allergic women and subsequently exposed to nickel sulphate in vitro. The level of this mRNA (determined by employing real-time polym...

journal_title：Immunopharmacology and immunotoxicology

authors： Falsafi-Amin H,Holst M,Lundeberg L

更新日期：2008-01-01 00:00:00

abstract：:Several studies outline the imbalance of phagocyte functions in chronic obstructive pulmonary disease (COPD). In this regard, here, we have assessed either monocyte- and polymorphonuclear cell (PMN)-mediated chemotactic, phagocytic and killing capacities or PMN-triggered metabolic pathway in a group of COPD patients b...

journal_title：Immunopharmacology and immunotoxicology

authors： Tortorella C,Ottolenghi A,Moretti AM,Jirillo E,Antonaci S

更新日期：1992-01-01 00:00:00

abstract：:Atractylenolide I (ATL-I) is a bioactive component of Rhizoma Atractylodis macrocephalae. Although increasing evidence shows that ATL-I has an anti-inflammatory effect, the anti-inflammatory molecular mechanism of ATL-I is still unknown. In this study, we investigated the effect of ATL-I on cell viability by 3-(4, 5-D...

journal_title：Immunopharmacology and immunotoxicology

authors： Ji G,Chen R,Zheng J

更新日期：2014-12-01 00:00:00

abstract：:Nervous and immune systems are connected by several mutual links, thus constituting a diffuse functional network in the body. In particular, neurohormones, neuropeptides, and cytokines represent the major mediators of the so-called psychoneuroendocrinoimmune axis. In this review, special emphasis is placed on certain ...

journal_title：Immunopharmacology and immunotoxicology

authors： Amati L,Selicato F,Ranieri M,Megna M,Galantino M,Miniello S,Megna G,Jirillo E

更新日期：2006-01-01 00:00:00

abstract：:A competitive enzyme-linked immunosorbent assay (ELISA) with generated mouse anti-consensus interferon (CIFN) antibody was developed for quantitative determination of pegylated consensus interferon (PEG-CIFN) in rhesus monkey serum. The operational concentrations of the original assay were determined using the chessbo...

journal_title：Immunopharmacology and immunotoxicology

authors： Cao J,Du Y,Tian H,Gao XD,Yao WB

更新日期：2009-01-01 00:00:00

abstract：:Engystol-N at the doses of 10(-4) and 10(-8) in isolated human leukocytes stimulates the superoxide anion generation by neutrophils and the cytokine(s) production by T lymphocytes. In whole blood the same concentrations of the drug produce the decrease of the superoxide anion generation of neutrophils, this inhibiting...

journal_title：Immunopharmacology and immunotoxicology

authors： Fimiani V,Cavallaro A,Ainis O,Bottari C

更新日期：2000-02-01 00:00:00

abstract：:We have developed an in vitro system to model the interactions of drugs used to treat transplant rejection. This system consists of stimulation of human lymphocytes with a primary mitogen (anti-T-cell receptor complex antibodies (OKT3 or wt31)) and treatment with a primary immunosuppressive drug (ISD) (Cyclosporine A ...

journal_title：Immunopharmacology and immunotoxicology

authors： Weaver JL,Pine PS,Aszalos A

更新日期：1994-05-01 00:00:00

abstract：CONTEXT:Foeniculum vulgare (F. vulgare) is traditionally used to treat inflammatory diseases. Recently, anti-inflammatory and antioxidant activities of methanol extract of the fruits of F. vulgare were reported. To identify biologically active compounds responsible for the anti-inflammatory activity, we isolated four c...

journal_title：Immunopharmacology and immunotoxicology

authors： Yang IJ,Lee DU,Shin HM

更新日期：2015-06-01 00:00:00

abstract：:Many flavonoids were demonstrated to possess the antiallergic effect. Here we detected whether apigenin, a flavonoid, can attenuate allergen-induced airway inflammation and what is the possible mechanism in a murine model of asthma. Apigenin decreased the degree of the inflammatory cell infiltration, airway hyperrespo...

journal_title：Immunopharmacology and immunotoxicology

authors： Li RR,Pang LL,Du Q,Shi Y,Dai WJ,Yin KS

更新日期：2010-09-01 00:00:00