Promotion of wound collagen formation in normal and diabetic mice by quadrol.

abstract：:CD69, also known as activation inducer molecule, very early activation antigen, MLR-3 and Leu-23, is a member of the natural killer (NK) cell gene complex family of signal transducing receptors. CD69 is as a type II transmembrane glycoprotein with a C-type lectin binding domain in the extracellular portion of the mole...

journal_title：Immunopharmacology and immunotoxicology

authors： Marzio R,Mauël J,Betz-Corradin S

更新日期：1999-08-01 00:00:00

abstract：:Hematopoietic cytokines such as interleukin (IL)-3, IL-5, and granulocyte macrophage colony-stimulating factor (GM-CSF) play a fundamental role in eosinophil functions in allergic asthma. The intracellular signal transduction mechanisms of these cytokines regulating the activation of eosinophils have been potential th...

journal_title：Immunopharmacology and immunotoxicology

authors： Ip WK,Wong CK,Wang CB,Tian YP,Lam CW

更新日期：2005-01-01 00:00:00

abstract：:Luminol-enhanced chemiluminescence assay was used to detect the surface expression and the consequent activation of receptors (FcRI and FcRII) of murine macrophages (M phi s). When murine IgG2a was used for the specific detection of FcRI and IgG2b for FcRII, a newly established procedure enabled us to detect the activ...

journal_title：Immunopharmacology and immunotoxicology

authors： Majima T,Itoh K,Yatsu J,Yoshie O,Ishida N

更新日期：1989-01-01 00:00:00

abstract：:Ponesimod, a novel selective sphingosine-1-phosphate 1 receptor modulator in the development for the treatment of autoimmune diseases, dose-dependently reduced lymphocyte counts in peripheral blood of healthy subjects. It rapidly and transiently reduced the number of circulating T and B cells, but not natural killer c...

journal_title：Immunopharmacology and immunotoxicology

authors： D'Ambrosio D,Steinmann J,Brossard P,Dingemanse J

更新日期：2015-02-01 00:00:00

abstract：:Traditionally venoms are used from thousands of years to treat pain, inflammation, and arthritis. In Ayurveda "Suchika Voron" and "Shodhona" were practiced against pain. In the present study, venom composition of the Indian honeybee Apis florea (AF), Apis dorsata (AD), and Apis cerana indica (AC) were analyzed using e...

journal_title：Immunopharmacology and immunotoxicology

authors： Nipate SS,Hurali PB,Ghaisas MM

更新日期：2015-04-01 00:00:00

abstract：:The aim of the present study was to investigate putative mechanisms implicated in the impaired phagocytic response of spontaneously hypertensive rats (SHR)1. The effect of in vitro treatment with isoproterenol (ISO), a beta-adrenergic drug, on phagocytosis and respiratory burst by splenic macrophages (SpMø) from normo...

journal_title：Immunopharmacology and immunotoxicology

authors： Serio M,Potenza MA,Montagnani M,Mansi G,Mitolo-Chieppa D,Jirillo E

更新日期：1996-05-01 00:00:00

abstract：:Inflammation is a physiological process essential for maintaining homeostatic mechanisms in human, but however, exaggerated inflammatory responses are closely related to many chronic diseases. Cadmium (Cd) is a heavy metal with high toxicity when present in food, water and air has the potential of eliciting inflammato...

journal_title：Immunopharmacology and immunotoxicology

authors： Hossein-Khannazer N,Azizi G,Eslami S,Alhassan Mohammed H,Fayyaz F,Hosseinzadeh R,Usman AB,Kamali AN,Mohammadi H,Jadidi-Niaragh F,Dehghanifard E,Noorisepehr M

更新日期：2020-02-01 00:00:00

abstract：:Temporary henna-based tattoos, particularly popular among western tourists holidaying in exotic places, can expose to the risk to develop allergic reactions. Although hypersensitivity to henna is extremely rare, para-phenylenediamine, which is sometimes added to henna to obtain a dark, blackish color, is a frequent co...

journal_title：Immunopharmacology and immunotoxicology

authors： Calogiuri G,Foti C,Bonamonte D,Nettis E,Muratore L,Angelini G

更新日期：2010-12-01 00:00:00

abstract：:Objective: Little is known about the exact underlying molecular mechanisms of the hepatoprotective effect of carvacrol against liver fibrosis. In the current study, we aimed to investigate the effect of carvacrol on the suppression of liver fibrosis progression via regulation of yes-associated protein (YAP) and transc...

journal_title：Immunopharmacology and immunotoxicology

authors： Mohseni R,Karimi J,Tavilani H,Khodadadi I,Hashemnia M

更新日期：2019-02-01 00:00:00

abstract：:We studied the effect of pyridoxine deficiency state on the responses of human lymphocytes to certain mitogenic factors. Deoxypyridoxine (DB6), a potent pyridoxine antagonist, considerably inhibited Bromodeoxyuridine (BrdU) incorporation into the newly synthesized DNA of lymphocytes cultured with Phytohemagglutinin (P...

journal_title：Immunopharmacology and immunotoxicology

authors： Scountzou J,Malisiovas N,Antoniadis A,Trakatellis A

更新日期：1989-01-01 00:00:00

abstract：:Enhanced glucose utilization was observed in continuous cultures of macrophages in medium containing 4mM Quadrol, [N,N,N',N',Tetrakis(2-hydroxypropyl)ethylenediamine]. This enhancement was both time and concentration dependent. Radiolabeled 4mM Quadrol, after incubation with macrophages for 60 minutes, was shown to be...

journal_title：Immunopharmacology and immunotoxicology

authors： Bhide MV,Smith DJ

更新日期：1987-01-01 00:00:00

abstract：:The immune effects of acebutolol, a beta-blocker, are investigated in various strains of mice. In 6-12 weeks old C57Bl/6 female mice, an increase in the number of immunoglobulin secreting cells is observed only at the age of 9 weeks. At that age, such an effect is seen neither in C57Bl/6 male mice nor in female mice f...

journal_title：Immunopharmacology and immunotoxicology

authors： In S,Lulé J,Fournié GJ

更新日期：1990-01-01 00:00:00

abstract：CONTEXT:The pentapeptide YGSRS is originated from coffee bean, while its pharmacological features have little been examined. OBJECTIVES:We investigated the effects of YGSRS on proliferation, cytokine production and CD4+ CD25+ Foxp3+ regulatory T (Treg) cell frequency of human peripheral blood mononuclear cells (PBMCs)...

journal_title：Immunopharmacology and immunotoxicology

authors： Nakamura Y,Hayakawa A,Ishizawa H,Kamei Y,Tanaka S,Onda K,Sugiyama K,Hirano T

更新日期：2015-06-01 00:00:00

abstract：:Chronic administration of oxytetracycline (OXT) (incorporated at a level of 0.05 g per kg of feed for 50 days) to pigeons, significantly decreased total leukocyte and lymphocyte counts, increased heterophil:lymphocyte ratio and lysosomal enzyme activity, and decreased reticuloendothelial system function compared with ...

journal_title：Immunopharmacology and immunotoxicology

authors： Al-Ankari AS

更新日期：2005-01-01 00:00:00

abstract：CONTEXT:Foeniculum vulgare (F. vulgare) is traditionally used to treat inflammatory diseases. Recently, anti-inflammatory and antioxidant activities of methanol extract of the fruits of F. vulgare were reported. To identify biologically active compounds responsible for the anti-inflammatory activity, we isolated four c...

journal_title：Immunopharmacology and immunotoxicology

authors： Yang IJ,Lee DU,Shin HM

更新日期：2015-06-01 00:00:00

abstract：:A competitive enzyme-linked immunosorbent assay (ELISA) with generated mouse anti-consensus interferon (CIFN) antibody was developed for quantitative determination of pegylated consensus interferon (PEG-CIFN) in rhesus monkey serum. The operational concentrations of the original assay were determined using the chessbo...

journal_title：Immunopharmacology and immunotoxicology

authors： Cao J,Du Y,Tian H,Gao XD,Yao WB

更新日期：2009-01-01 00:00:00

abstract：:A human THP-1 monocyte cell line culture system has been utilized to observe the effect of granulocyte macrophage colony stimulating factor (GM-CSF) supplementation with lipopolysaccharide (LPS) of oral microorganisms to stimulate monocyte/macrophage functional activity. LPS of oral microorganisms, Fusobacterium nucle...

journal_title：Immunopharmacology and immunotoxicology

authors： Baqui AA,Meiller TF,Turng BF,Kelley JI,Falkler WA Jr

更新日期：1998-11-01 00:00:00

abstract：:This study aimed to evaluate the immunomodulatory effects of Pleurotus florida on cell-mediated immunity in Balb/c mice. Aqueous extract of P. florida was isolated, lyophilized, and stored in refrigerator until application. Forty female Balb/c mice were randomly divided into seven test and one control groups. Four gro...

journal_title：Immunopharmacology and immunotoxicology

authors： Sedaghat R,Ghazanfari T

更新日期：2011-03-01 00:00:00

abstract：:Thalidomide causes congenital anomalies and it is immunomodulatory. These properties could be explained by an ability to alter the orderly process of programmed cell death during embryogenesis and modulation of apoptosis of lymphoid and/or myeloid cells in the immune response. Apoptosis of lymphoid and myeloid cells w...

journal_title：Immunopharmacology and immunotoxicology

authors： Aseffa A,Dietrich MA,Shannon EJ

更新日期：1997-08-01 00:00:00

abstract：:In the present study, we introduce a new class of organometallic compound, the Biphosphinic Palladacycle Complex [Pd (C2, N-S(-)(dmpa)(dppf)] Cl (BPC), as an angiotensin-I converting-enzyme inhibitor (ACEI) with hematological regulation properties. When BPC was assayed as a competitive inhibitor over the hydrolysis of...

journal_title：Immunopharmacology and immunotoxicology

authors： Caires AC,Oliveira CR,Smith MC,Hemerly JP,Juliano MA,Bincoletto C

更新日期：2004-01-01 00:00:00

abstract：:Formyl peptides are oligopeptides released by Gram-negative bacteria. So far, specific formyl peptide receptors (FPRs) have been described in mammals only. FPRs are seven-transmembrane G-coupled molecules and make up a relatively homogeneous group, although exhibiting different levels of affinity for the ligands. We e...

journal_title：Immunopharmacology and immunotoxicology

authors： Panaro MA,Acquafredda A,Sisto M,Lisi S,Calvello R,Mitolo CI,Cianciulli A,Mitolo V

更新日期：2007-01-01 00:00:00

abstract：:We have previously obtained and elucidated the precise structure of a highly branched 1,3-β-D-glucan (with 6-monoglucopyranosyl side chains), Aureobasidium pullulans-fermented β-D-glucan (AP-FBG), from the fungus A. pullulans. However, the mechanism(s) of the effects of AP-FBG on in vitro mouse primary cells have not ...

journal_title：Immunopharmacology and immunotoxicology

authors： Tada R,Yoshikawa M,Kuge T,Tanioka A,Ishibashi K,Adachi Y,Tsubaki K,Ohno N

更新日期：2011-06-01 00:00:00

abstract：:The Scrophularia buergeriana (SB) has long been used to treat various diseases an account of its antimicrobial and anti-virus activity. However, it is unclear how SB regulates the immune responses. This study investigated the effect of SB on the production of cytokines in a human T-cell line, MOLT-4 cells, and mouse p...

journal_title：Immunopharmacology and immunotoxicology

authors： Kim SJ,Park JS,Myung NY,Moon PD,Choi IY,An HJ,Kim NH,Na HJ,Kim DH,Kim MC,An NH,Kim IK,Lee JY,Jeong HJ,Um JY,Kim HM,Hong SH

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of ginsenoside metabolite compound K (CK) on adjuvant-induced arthritis (AA) rats and the partial mechanisms focused on the function of immunocyte (B cell and macrophage) and effectors' cell (fibroblast-like synoviocyte, FLS). METHODS:Animals were divided randomly into nine groups ...

journal_title：Immunopharmacology and immunotoxicology

authors： Wu H,Chen J,Wang Q,Jia X,Song S,Yuan P,Liu K,Liu L,Zhang Y,Zhou A,Wei W

更新日期：2014-04-01 00:00:00

abstract：:Lymphocytes predominantly express delayed rectifier K(+)-channels (Kv1.3) in their plasma membranes, and the channels play crucial roles in the lymphocyte activation and proliferation. Since nonsteroidal anti-inflammatory drugs (NSAIDs), the most commonly used analgesic and antipyretic drugs, exert immunomodulatory ef...

journal_title：Immunopharmacology and immunotoxicology

authors： Kazama I,Maruyama Y,Murata Y

更新日期：2012-10-01 00:00:00

abstract：:We examined the effect of sulfapyridine on mast cell-mediated immediate-type allergic reactions. Sulfapyridine (1 and 10 microg/kg) significantly inhibited systemic allergic reaction induced by compound 48/80 in rats. Sulfapyridine (1 and 10 microg/kg) also inhibited significantly local mast cell-mediated immediate-ty...

journal_title：Immunopharmacology and immunotoxicology

authors： Kim HM,An NH,Yi BH,Chae HJ,Kim HR,Moon SJ,Kim JJ,Park ST,Baek SH

更新日期：2000-05-01 00:00:00

abstract：:Mercuric sulfide (HgS) is a major component of cinnabar, which has been used as a sedative drug in China for more than 2000 years. Because its toxicological effects are still unclear, we attempted to verify the toxic effects of HgS, focused on liver and immune organs such as the spleen and thymus. Male ICR mice were a...

journal_title：Immunopharmacology and immunotoxicology

authors： Son HY,Lee S,Park SB,Kim MS,Choi EJ,Singh TS,Bae Y,Kwack SJ,Kang TS,Shin HI,Baek MC,Kim SH

更新日期：2010-06-01 00:00:00

abstract：:We have developed an in vitro system to model the interactions of drugs used to treat transplant rejection. This system consists of stimulation of human lymphocytes with a primary mitogen (anti-T-cell receptor complex antibodies (OKT3 or wt31)) and treatment with a primary immunosuppressive drug (ISD) (Cyclosporine A ...

journal_title：Immunopharmacology and immunotoxicology

authors： Weaver JL,Pine PS,Aszalos A

更新日期：1994-05-01 00:00:00

abstract：:Host-parasite interactions and their outcome constitute a critical and challenging step in disease establishment in cutaneous leishmaniasis. In the present in vitro study we investigated the possible modulating effects of both sensory and autonomic neuropeptides that normally exist in human and mouse skin, on the upta...

journal_title：Immunopharmacology and immunotoxicology

authors： Ahmed AA,Wahbi AH,Nordlin K

更新日期：2001-08-01 00:00:00

abstract：:Lymphocyte proliferation assays are commonly used to quantify the effects of immunosuppressive drugs in animal models, but the influence of anesthetic agents on those assays is not well understood. We used a whole blood proliferation assay to compare lymphocyte proliferation in blood drawn from normal male Lewis rats ...

journal_title：Immunopharmacology and immunotoxicology

authors： Gummert JF,Otto G,Barten MJ,Morris RE

更新日期：1999-05-01 00:00:00