Activity of cefixime against Helicobacter pylori.

abstract：:The ability of antibiotics used in bronchopulmonary infections in cystic fibrosis (CF) patients to prevent Pseudomonas aeruginosa early biofilm formation was studied using a biofilm microtitre assay with 57 non-mucoid P. aeruginosa isolates (44 first colonisers and 13 recovered during the initial intermittent colonisa...

journal_title：International journal of antimicrobial agents

authors： Fernández-Olmos A,García-Castillo M,Maiz L,Lamas A,Baquero F,Cantón R

更新日期：2012-08-01 00:00:00

abstract：:We investigated the in vitro activity of various piperacillin and sulbactam combinations against Gram-negative bacterial isolates from Intensive Care Units (ICUs) in Taiwan. Antimicrobial susceptibility testing of 1030 bacterial isolates recovered from ICUs of nine major teaching hospitals was performed using the agar...

journal_title：International journal of antimicrobial agents

authors： Hung MN,Hsueh PR,Chang HT,Lee WS,Chou MY,Chen IS,Wang JH,Lin CF,Shyr JM,Ko WC,Wu JJ,Liu YC,Huang WK,Teng LJ,Liu CY,Luh KT

更新日期：2007-02-01 00:00:00

abstract：:Fluoroquinolone (FQ) resistance is usually caused by point mutations within the quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC and/or parE. However, little is known about the worldwide increase in FQ-resistant Escherichia coli or, more specifically, about the geographical distribution of QRDR mut...

journal_title：International journal of antimicrobial agents

authors： Uchida Y,Mochimaru T,Morokuma Y,Kiyosuke M,Fujise M,Eto F,Harada Y,Kadowaki M,Shimono N,Kang D

更新日期：2010-04-01 00:00:00

abstract：:Although cephalosporins are recommended as primary agents, moxifloxacin may be a suitable second-line antibiotic in cardiac surgery, especially if additional Gram-negative coverage is warranted. Cardiopulmonary bypass (CPB) may alter the pharmacokinetics of drugs in numerous ways. Since no such data exist, the aim of ...

journal_title：International journal of antimicrobial agents

authors： Wiesner G,Martin K,Gertler R,Braun SL,Tassani P,Lange R,Gruber M

更新日期：2013-05-01 00:00:00

abstract：:Resistance to chemotherapy is a common clinical problem in patients with infectious diseases as well as in patients with cancer. During treatment of infections or malignant tumors, the drug targets of prokaryotic or eukaryotic microorganisms and neoplastic cells are often found to be refractory to a variety of drugs t...

journal_title：International journal of antimicrobial agents

authors： Lage H

更新日期：2003-09-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide important pathogen in nosocomial infections. To investigate the extent of the problem in Taiwan, analysis for the period of 1981-1994 was carried out of prospective surveillance data from the National Taiwan University Hospital, a major university teach...

journal_title：International journal of antimicrobial agents

authors： Chang SC,Sun CC,Yang LS,Luh KT,Hsieh WC

更新日期：1997-03-01 00:00:00

abstract：:Triple therapy combining the protease inhibitor telaprevir with interferon-α and ribavirin is a promising new option for long-term treatment of hepatitis C. The interaction potential of telaprevir has not yet been fully elucidated. The in vitro potency of telaprevir to inhibit P-glycoprotein (P-gp, ABCB1) and breast c...

journal_title：International journal of antimicrobial agents

authors： Weiss J,Becker JP,Haefeli WE

更新日期：2014-02-01 00:00:00

abstract：:Pneumococcal infections elicited by Streptococcus pneumoniae (pneumococcus) (pneumonia, otitis media, sinusitis, meningitis) are frequently occurring diseases that are associated with considerable morbidity and mortality even in developed countries. Pneumococci colonise the nasopharynx of up to 50% of children, and up...

journal_title：International journal of antimicrobial agents

authors： Pletz MW,Maus U,Krug N,Welte T,Lode H

更新日期：2008-09-01 00:00:00

abstract：:The use of antibiotics, as any other drug, is regulated by the terms of its marketing authorisation, notified in the Summary of Product Characteristics (SPC). If a prescription is not in accordance with the SPC, the physician prescribes off-label. There is very little literature regarding off-label use of antibiotics ...

journal_title：International journal of antimicrobial agents

authors： Davido B,Bouchand F,Calin R,Makhloufi S,Lagrange A,Senard O,Perronne C,Villart M,Salomon J,Dinh A

更新日期：2016-06-01 00:00:00

abstract：:Chlorcyclizine HCl and ciprofloxacin HCl were shown to have anti-HIV activity. They possess virustatic and virucidal activities against HIV, a murine retrovirus (RV) and several other RNA and DNA viruses. These drugs were screened from a large number of compounds on the basis of in vitro mutagenicity and antimetabolit...

journal_title：International journal of antimicrobial agents

authors： Chakrabarty AN,Mookerjee M,Dastidar SG

更新日期：2000-04-01 00:00:00

abstract：:The antibacterial effects of six inorganic antibacterial agents were assessed using broth dilution and agar dilution tests on six pathogenic bacteria associated with oral infectious diseases: Streptococcus mutans (ATCC 25175), S. mutans (Ingbritt), Actinomyces viscosus (ATCC 15987), Lactobacillus casei (ATCC 393), Sta...

journal_title：International journal of antimicrobial agents

authors： Fang M,Chen JH,Xu XL,Yang PH,Hildebrand HF

更新日期：2006-06-01 00:00:00

abstract：:Until now, studies confirming the safety of glycopeptide restriction in the empirical treatment of prolonged fever and neutropenia included only nine children. In an open-label observational study, the use of teicoplanin in paediatric oncology patients was investigated. A period of unrestricted use (2001-2003) was com...

journal_title：International journal of antimicrobial agents

authors： Simon A,Gröger N,Wilkesmann A,Hasan C,Wiszniewsky G,Engelhart S,Kramer MH,Bode U,Ammann RA,Fleischhack G

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:Since the early 2000s, Escherichia coli resistance to third-generation cephalosporins (3GCs) has been increasing in all European countries, mainly due to the spread of extended spectrum β-lactamases (ESBLs). Here we present a retrospective study that combines resistance of E. coli to 3GCs and quinolones with...

journal_title：International journal of antimicrobial agents

authors： Jeanvoine A,Bouxom H,Leroy J,Gbaguidi-Haore H,Bertrand X,Slekovec C

更新日期：2020-05-01 00:00:00

abstract：:Three pharmacokinetic/pharmacodynamic parameters--(i) the peak concentration to the minimum inhibitory concentration ratio (C(max)/MIC); (ii) the area under the concentration-time curve to MIC ratio (AUC(24h)/MIC); and (iii) the time the concentration exceeds the MIC (T>MIC)--are important predictors of the clinical e...

journal_title：International journal of antimicrobial agents

authors： Van Bambeke F,Tulkens PM

更新日期：2001-01-01 00:00:00

abstract：:The in vitro susceptibilities of 192 consecutive clinical strains of Pasteurella spp. isolated between 1996 and 2003 from soft tissue pus (n = 146), respiratory tract specimens (n = 38) and blood (n = 8) were studied by an agar dilution method. All isolates were susceptible to minocycline, cefotaxime, ofloxacin, cipro...

journal_title：International journal of antimicrobial agents

authors： Lion C,Conroy MC,Carpentier AM,Lozniewski A

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:Infective endocarditis (IE) is a severe infection, and a leading cause of mortality and morbidity. Due to its favourable microbiological and pharmacological characteristics, daptomycin is routinely used in clinical practice for treating IE. METHODS:A prospective study was conducted at a large tertiary-care hos...

journal_title：International journal of antimicrobial agents

authors： Russo A,Peghin M,Givone F,Ingani M,Graziano E,Bassetti M

更新日期：2019-10-01 00:00:00

abstract：:D-Alanylgriseoluteic acid (AGA) is a potent antimicrobial phenazine compound produced by Pantoea agglomerans (Erwinia herbicola) Eh1087. Susceptibility tests against a range of microbes indicated that AGA had a broad spectrum of antimicrobial activity and was particularly active against Gram-positive pathogens. Compar...

journal_title：International journal of antimicrobial agents

authors： Giddens SR,Bean DC

更新日期：2007-01-01 00:00:00

abstract：:Renal, liver, heart and lung transplantation are now considered to be the standard therapeutic interventions in patients with end-stage organ failure. Infectious complications following solid organ transplantation (SOT) are relatively common owing to the transplant recipient's overall immunosuppressed status. The inci...

journal_title：International journal of antimicrobial agents

authors： Salavert M

更新日期：2008-11-01 00:00:00

abstract：:Nepeta cataria L., commonly known as catnip, is a perennial herb with a considerable folkloric reputation. A diethyl ether extract of this plant has been shown to have antimicrobial activity against fungi and Gram-positive bacteria. The aim of this work was to study the activity of N. cataria extract on 44 Staphylococ...

journal_title：International journal of antimicrobial agents

authors： Nostro A,Cannatelli MA,Crisafi G,Alonzo V

更新日期：2001-12-01 00:00:00

abstract：:Helicobacter infection, one of the most common bacterial infections in man worldwide, is a type 1 carcinogen and the most important risk factor for gastric cancer. Helicobacter pylori bacterial factors, components of the host genetics and immune response, dietary cofactors and decreased acid secretion resulting in bac...

journal_title：International journal of antimicrobial agents

authors： Stoicov C,Saffari R,Houghton J

更新日期：2009-05-01 00:00:00

abstract：:Lovastatin is a prodrug that is hydrolysed in vivo to β-hydroxy acid lovastatin, which inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-Co-A) reductase (HMGR), thereby lowering cholesterol in humans. A side effect of lovastatin is inhibition of isoprenoid synthesis and cell membrane formation in methanogenic Archae...

journal_title：International journal of antimicrobial agents

authors： Demonfort Nkamga V,Armstrong N,Drancourt M

更新日期：2017-02-01 00:00:00

abstract：:In this study, 619 individual Escherichia coli isolates from food-producing and companion animals were analysed to determine the prevalence of the cephalosporinase gene blaCMY-2. In total, 18 CMY-2-producers (2.9%) were detected and exhibited multidrug-resistant phenotypes. One of the CMY-2-producers was found to poss...

journal_title：International journal of antimicrobial agents

authors： Fang LX,Sun J,Li L,Deng H,Huang T,Yang QE,Li X,Chen MY,Liao XP,Liu YH

更新日期：2015-08-01 00:00:00

abstract：:In vitro and in vivo anti-Candida albicans and anti-Aspergillus fumigatus activities of NND-502, a new imidazole-antimycotic, were compared with those of fluconazole (FCZ), itraconazole (ITZ) and/or amphotericin B (AmB). NND-502 exhibited strong in vitro antifungal activity against both fungal species; its MIC against...

journal_title：International journal of antimicrobial agents

authors： Niwano Y,Kuzuhara N,Goto Y,Munechika Y,Kodama H,Kanai K,Yoshida M,Miyazaki T,Yamaguchi H

更新日期：1999-08-01 00:00:00

abstract：:The whole-genome sequences of 24 isolates of Neisseria gonorrhoeae with elevated minimum inhibitory concentrations (MICs) to azithromycin (≥2.0 µg/mL) were analyzed against a modified sequence derived from the whole-genome sequence of N. gonorrhoeae FA1090 to determine, by signal ratio, the number of mutant copies of ...

journal_title：International journal of antimicrobial agents

authors： Johnson SR,Grad Y,Abrams AJ,Pettus K,Trees DL

更新日期：2017-02-01 00:00:00

abstract：:Antimicrobial peptides (AMPs) are produced by all forms of living organisms and represent a novel class of antibiotics to treat infectious diseases. In this study, 29 AMPs of varying length and characteristics were synthesised chemically and were evaluated for their ability to inhibit the growth of Bacillus globigii, ...

journal_title：International journal of antimicrobial agents

authors： Dawson RM,McAllister J,Liu CQ

更新日期：2010-10-01 00:00:00

abstract：:The last decade has been remarkable for the dramatic increase in the prevalence of serious fungal infections in patients with haematological disorders and neutropenic cancer patients. The mortality rate of deep-seated infection has been in excess of 90% and there is no doubt that this is one of the greatest challenges...

journal_title：International journal of antimicrobial agents

authors： Hann IM,Prentice HG

更新日期：2001-03-01 00:00:00

abstract：:The Bureau of National Health Insurance (BNHI) of Taiwan issued a new reimbursement regulation effective from 1 February 2001 forbidding the use of antimicrobials in ambulatory patients with upper respiratory infections (URI) without evidence of bacterial infection. We evaluated the effect of this regulation by analys...

journal_title：International journal of antimicrobial agents

authors： Ho M,Hsiung CA,Yu HT,Chi CL,Chang HJ

更新日期：2004-05-01 00:00:00

abstract：:Melioidosis is a fatal community-acquired infection endemic in tropical areas. Ten isolates of the causative microorganism were subjected to time-kill study using a range of ceftazidime concentrations. This study demonstrated that a ceftazidime concentration of eight times the minimum inhibitory concentration yielded ...

journal_title：International journal of antimicrobial agents

authors： Soontornpas C,Saraya S,Chulasiri M,Chindavijak B,Mootsikapun P

更新日期：2005-11-01 00:00:00

abstract：:Antimicrobial resistance and sulphonamide resistance determinants were studied in 20 co-trimoxazole resistant Escherichia coli in faecal samples from healthy children in Bolivia and Peru. Methods used were disc diffusion susceptibility tests, PCR, sequence analysis and plasmid conjugation assays. All isolates but one ...

journal_title：International journal of antimicrobial agents

authors： Infante B,Grape M,Larsson M,Kristiansson C,Pallecchi L,Rossolini GM,Kronvall G

更新日期：2005-04-01 00:00:00

abstract：:Here we describe a patient undergoing extensive abdominal surgery and hyperthermic intraperitoneal chemotherapy due to primary adenocarcinoma in the sigmoid colon with peritoneal carcinomatosis. During hospitalisation the patient suffered from bacteraemia with a multidrug-resistant Bacteroides fragilis isolate. Whole-...

journal_title：International journal of antimicrobial agents

authors： Ank N,Sydenham TV,Iversen LH,Justesen US,Wang M

更新日期：2015-07-01 00:00:00