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Time-kill curves as a tool for targeting ceftazidime serum concentration during continuous infusion for treatment of septicaemic melioidosis.

Abstract：

:Melioidosis is a fatal community-acquired infection endemic in tropical areas. Ten isolates of the causative microorganism were subjected to time-kill study using a range of ceftazidime concentrations. This study demonstrated that a ceftazidime concentration of eight times the minimum inhibitory concentration yielded an optimal bactericidal effect and should be the target concentration administered by continuous infusion.

journal_name

Int J Antimicrob Agents

journal_title

International journal of antimicrobial agents

authors

Soontornpas C,Saraya S,Chulasiri M,Chindavijak B,Mootsikapun P

doi

10.1016/j.ijantimicag.2005.07.016

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

403-7

issue

5

eissn

0924-8579

issn

1872-7913

pii

S0924-8579(05)00226-8

journal_volume

26

pub_type

杂志文章

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