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Acquired sulphonamide resistance genes in faecal Escherichia coli from healthy children in Bolivia and Peru.

Abstract：

:Antimicrobial resistance and sulphonamide resistance determinants were studied in 20 co-trimoxazole resistant Escherichia coli in faecal samples from healthy children in Bolivia and Peru. Methods used were disc diffusion susceptibility tests, PCR, sequence analysis and plasmid conjugation assays. All isolates but one were resistant to at least two different classes of antimicrobials; 19 isolates also carried at least one sul-gene. The most frequent gene was sul2 followed by sul1 and sul3, which was detected in one isolate. This is the first observation of sul3 on the American continent. In conclusion, the high prevalence of sul-genes in this material of faecal commensal E. coli isolates points to a potential role of the faecal flora in the emergence and spread of antimicrobial resistance.

journal_name

Int J Antimicrob Agents

journal_title

International journal of antimicrobial agents

authors

Infante B,Grape M,Larsson M,Kristiansson C,Pallecchi L,Rossolini GM,Kronvall G

doi

10.1016/j.ijantimicag.2004.12.004

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

308-12

issue

4

eissn

0924-8579

issn

1872-7913

pii

S0924-8579(05)00021-X

journal_volume

25

pub_type

杂志文章

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