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Increasing nosocomial infections of methicillin-resistant Staphylococcus aureus at a teaching hospital in Taiwan.

Abstract：

:Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide important pathogen in nosocomial infections. To investigate the extent of the problem in Taiwan, analysis for the period of 1981-1994 was carried out of prospective surveillance data from the National Taiwan University Hospital, a major university teaching hospital in Taiwan. The number of nosocomial MRSA infections increased from five in 1981 to 133 in 1994, and the incidence increased from 0.2 episodes/1000 discharges in 1981 to 2.9 episodes/1000 discharges in 1994. The most common infection site was surgical wounds, which accounted for 26.3% of total 577 episodes of nosocomial MRSA infections during the study period. However, bacteraemia has become more and more common during the past 14 years. MRSA infections occured more frequently in patients stayed in the burn unit and other intensive care units than in the general wards. Other than oxacillin, the resistance rate to many other antibiotics also increased in S. aureus strains causing nosocomial infections in this hospital. Vancomycin remained active to all these S. aureus strains, even until 1994.

journal_name

Int J Antimicrob Agents

journal_title

International journal of antimicrobial agents

authors

Chang SC,Sun CC,Yang LS,Luh KT,Hsieh WC

doi

10.1016/s0924-8579(96)00360-3

subject

Has Abstract

pub_date

1997-03-01 00:00:00

pages

109-14

issue

2

eissn

0924-8579

issn

1872-7913

pii

S0924-8579(96)00360-3

journal_volume

8

pub_type

杂志文章

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