Dilution rate as a determinant of mycelial morphology in continuous culture.

Abstract:

:The morphology of mycelial fungi in liquid culture effects culture rheology and this in turn may affect product yield. It is therefore important to understand how environmental factors influence mycelial morphology and this paper describes the effect of dilution rate on two strains of Fusarium graminearum, the relatively sparsely branched parental strain (A3/5) and a relatively highly branched "colonial" variant (C106). At any given dilution rate, the concentration of mycelial fragments present at steady state of both strains remained approximately constant with time, suggesting that mycelial fragmentation occurred in a regular manner. However, for both strains fragment concentration decreased with increasing dilution rate. The strains had a similar morphology at a dilution rate of 0.07 h(-1). The length of the hyphal growth unit of A3/5 increased with increase in dilution rate, while that of C106 decreased with increase in dilution rate. At all dilution rates, C106 produced up to ten times more macroconidia than A3/5.

journal_name

Biotechnol Bioeng

authors

Wiebe MG,Trinci AP

doi

10.1002/bit.260380110

subject

Has Abstract

pub_date

1991-06-05 00:00:00

pages

75-81

issue

1

eissn

0006-3592

issn

1097-0290

journal_volume

38

pub_type

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