Abstract:
:The specific activity of cyclic adenosine 3':5'-monophosphate phosphodiesterase was measured in lymphocytes isolated from the blood of normal subjects, from patients with chronic lymphocytic leukemia, and from tonsil tissue. The mean specific activity of cyclic adenosine 3':5'-monophosphate phosphodiesterase in the lymphocytes from patients with untreated chronic lymphocytic leukemia was lower than that in lymphocytes from the blood of normal subjects or from tonsils. Cyclic adenosine 3':5'-monophosphate phosphodiesterase levels did not correlate with differences in B- and T-cell lymphocyte subpopulations or with peripheral blood lymphocyte counts.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Scher NS,Quagliata F,Malathi VG,Faig D,Melton RA,Silber Rsubject
Has Abstractpub_date
1976-11-01 00:00:00pages
3958-62issue
11 Pt 1eissn
0008-5472issn
1538-7445journal_volume
36pub_type
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