Detection of mutant-specific responses by macrophage migration inhibition reactions induced by wild-type and mutant polyoma viruses and polyoma virus-infected cells.

Abstract:

:Macrophage migration inhibition responses of mice immunized with mutant polyoma viruses or with cells transformed and/or infected by them have been studied. The macrophage migration inhibition reaction revealed individual differences. In several cases, mice immunized with a mutant virus responded preferentially or exclusively to extracts of cells transformed or infected with the corresponding mutant. Moreover, in the macrophage migration inhibition test, mutant viruses were usually less immunogenic than were the corresponding transformed-infected cells.

journal_name

Cancer Res

journal_title

Cancer research

authors

Szigeti R,Dalianis T,Ramqvist T,Ito Y,Klein G

subject

Has Abstract

pub_date

1984-03-01 00:00:00

pages

1077-80

issue

3

eissn

0008-5472

issn

1538-7445

journal_volume

44

pub_type

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