Abstract:
BACKGROUND:This retrospective analysis evaluated the association of age and weight with cycle control in women using either of two formulations of low-estrogen-dose oral contraceptives.
STUDY DESIGN:Data for this secondary analysis were derived from a randomized multicenter trial assessing the efficacy and safety of norgestimate (NGM) 180/215/250 mcg/ethinyl estradiol (EE) 25 mcg (n=1506) and norethindrone acetate 1 mg/EE 20 mcg (n=1057). In this retrospective analysis, the incidence of breakthrough bleeding/spotting (BTB/S) was evaluated in women stratified by age (18-24, 25-34 and >34 years) and weight (
journal_name
Contraceptionjournal_title
Contraceptionauthors
Hampton RM,Zhang HF,Barnowski C,Wan GJdoi
10.1016/j.contraception.2008.02.007subject
Has Abstractpub_date
2008-06-01 00:00:00pages
415-9issue
6eissn
0010-7824issn
1879-0518pii
S0010-7824(08)00092-9journal_volume
77pub_type
杂志文章,多中心研究,随机对照试验相关文献
CONTRACEPTION文献大全abstract::There is agreement that the relative risk of developing pelvic inflammatory disease (PID) increases among women who use the intrauterine contraceptive device (IUD). The role of Chlamydia in causing PID among IUD users is not clear. The present study demonstrates that Chlamydia trachomatis growth can be inhibited in cu...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(89)90041-3
更新日期:1989-06-01 00:00:00
abstract::The objectives of this study were to define the "normal" position of the T-shaped intrauterine device (IUD) in the endometrial cavity, using transvaginal ultrasound, and to compare the IUD's position in women with and without complaints of bleeding and/or pain. Vaginal ultrasound was carried out in women who had used ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(97)00072-3
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:Quantitative evaluation of properties of bromhexine (B) for expression of uterine proteins in ovariectomized (OVX) and pregnant rats. MATERIALS AND METHODS:Expression of proteins through SDS-PAGE, along with incorporation of glycosidic moieties, was conducted in pregnant and OVX rats under B influence. These f...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2005.11.006
更新日期:2006-06-01 00:00:00
abstract::The efficacy and acceptability of a levonorgestrel-releasing intravaginal ring (IVR) for contraception was assessed in a British cohort studied as part of a multicentre, multinational clinical trial performed under the auspices of the World Health Organisation. One-hundred-and-fifty women took part in the study in two...
journal_title:Contraception
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/0010-7824(91)90040-m
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:In response to concerns about serious infections following medical abortion, in early 2006 the Planned Parenthood Federation of America changed the route of misoprostol administration from vaginal to buccal and required either routine antibiotic coverage or universal screening and treatment for chlamydia; in...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2010.08.022
更新日期:2011-04-01 00:00:00
abstract::This randomized, double-blind, placebo-controlled exploratory study examined the efficacy and safety of a low-dose oral contraceptive (Mircette), desogestrel/ethinyl estradiol [DSG/EE] and ethinyl estradiol [EE]) in relieving the symptoms of dysmenorrhea. Twenty-three clinics in the United States enrolled 77 women (ag...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0010-7824(02)00414-6
更新日期:2002-12-01 00:00:00
abstract::A large international multi-center IUD data set (N = 5520) coordinated by Family Health International was analysed to determine if the uterine position of a woman (anteverted, mid-positioned or retroverted) affects the ease of IUD insertion and if knowledge of uterine position would diminish insertion-related problems...
journal_title:Contraception
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/0010-7824(90)90059-5
更新日期:1990-05-01 00:00:00
abstract::Eight investigators, using a common protocol, studied the use of intramuscular (15S)-15-methyl prostaglandin F2 alpha to abort midtrimester pregnancies which had failed treatment by other methods in 398 cases. Results of treatment of 3 subgroups, defined by reason for primary treatment failure, are presented. The comb...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(80)90088-8
更新日期:1980-12-01 00:00:00
abstract::This study examines contraceptive delivery characteristics and their association with contraceptive behavior. Data were collected in telephone interviews from a national sample of 1057 women who were using female contraceptives. The overwhelming majority of the sample obtained contraceptive services from gynecologists...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(89)90074-7
更新日期:1989-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the impact on lipid and carbohydrate variables of a combined one-third ethinyl estradiol (EE)/levonorgestrel (LNG) dose reduction in oral contraceptives. METHODS:In an open-label, randomized study, a dose-reduced oral contraceptive containing 20 microg EE and 100 microg LNG (20 EE/100 LNG) was c...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.contraception.2004.08.017
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:The objective was to describe the efficacy of medical abortion using mifepristone and misoprostol for gestations less than 6 weeks. STUDY DESIGN:We searched PubMed and Cochrane databases for articles in any language that examined the success of mifepristone and misoprostol abortion at gestational ages <42 da...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2017.09.006
更新日期:2018-02-01 00:00:00
abstract::A review of new Zoapatle publications was made, including five chemical compounds characterized recently. Relative potency of Kaurenoic acid, Kauradienoic acid (its mixture), Zoapatanol and Montanol was estimated in an in vitro guinea pig uterine assay. Kaurene compounds were several times more potent than Montanol an...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/0010-7824(85)90084-8
更新日期:1985-05-01 00:00:00
abstract::Eleven normally menstruating women, who had earlier been immunized with NII beta-hCG vaccine but had no detectable anti-hCG antibody titres, were selected as controls for the hCG challenge test using 1000/2000 I.U. The test was repeated in five of them after a booster immunization, which raised antibody titres to 18-4...
journal_title:Contraception
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/0010-7824(91)90035-e
更新日期:1991-10-01 00:00:00
abstract::This study is concerned with contraceptive use among the currently married adolescents in Bangladesh utilizing the 1989 Bangladesh Fertility Survey (BFS) data. The study analyzes the factors affecting the current use of contraception among the adolescents through bivariate and multivariate logistic regression analysis...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(95)00149-5
更新日期:1995-09-01 00:00:00
abstract::A comparative study of the performance of multi-sizes of the Mahua Ring inserted following measurement of the uterine cavity and one size of the same ring assigned at random was carried out from November 1984 to September 1985 at two hospitals in Tianjin. The experiences of 800 acceptors were analysed by life-table te...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0010-7824(90)90048-z
更新日期:1990-10-01 00:00:00
abstract::To describe surface abnormalities found by scanning electron microscopy of non-lubricated latex condoms, thirty samples of 15 condoms were photographed at low (26-94x), medium (240-940x) and high (> 1000x) magnification. Each sample was initially scanned at low magnification to determine the presence and location of s...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(95)00259-6
更新日期:1996-01-01 00:00:00
abstract::Sulprostone was given intramuscularly in two dose schedules of 0.5 mg at 4 hourly intervals for 8 doses and 1.0 mg at 8-hour intervals for 4 doses to 56 women in the 12th-20th week of gestation coming for termination of pregnancy. Forty-nine of them aborted within the 30-hour observation period, giving a success rate ...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0010-7824(82)90028-2
更新日期:1982-02-01 00:00:00
abstract::The aim of this study was to characterize the bleeding pattern, the outcome of pregnancies and the levonorgestrel plasma levels associated with method failures in Norplant implants users. Nineteen pregnancies are reported in 458 woman and 21,589 woman-months observed during the first eight years of Norplant use. Pregn...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(86)90096-x
更新日期:1986-04-01 00:00:00
abstract::In a cross-over study with orally administered desogestrel (0.150 mg) plus ethinyloestradiol (0.030 mg) and 3-keto-desogestrel (0.150 mg) plus ethinyloestradiol (0.030 mg) in ten women under steady-state conditions, the serum levels of 3-keto-desogestrel were monitored by radioimmunoassay. No statistically significant...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(86)90047-8
更新日期:1986-06-01 00:00:00
abstract:OBJECTIVES:To assess factors associated with pregnancy fatalism among U.S. adult women. STUDY DESIGN:I used data from the Change and Consistency in Contraceptive Use study, which collected information from a national sample of 4634 U.S. women aged 18-39 at baseline (59% response rate). I assessed pregnancy fatalism ba...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2018.05.015
更新日期:2018-10-01 00:00:00
abstract::After exposure of young male rats to gossypol acetic acid for various times, a reduction in the content of cellular and microtubular beta-tubulin was found in spermatocytes and spermatids. The content of tubulin was measured by enzyme-linked immunosorbent assay (ELISA). The results were expressed as micrograms tubulin...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(96)00240-5
更新日期:1997-01-01 00:00:00
abstract::Researchers, health care providers, women's health advocates, donors, and representatives of ministries of health convened in Bellagio, Italy, in July 1998, to assess the potential of medical methods of early pregnancy termination to improve the reproductive health of women in developing countries. Consensus was reac...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(98)00109-7
更新日期:1998-11-01 00:00:00
abstract::The use of progestogen-only contraceptives among women with sickle cell anemia has generated concerns about possible hematological and other clinical complications. Based on the literature, we assessed whether use of progestogen-only contraceptives is associated with adverse health effects among women with sickle cell...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/j.contraception.2005.08.010
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:This prospective study aimed to assess the possible effects of the levonorgestrel-releasing intrauterine system (LNG-IUS) on serum lipids and fasting blood glucose levels over a period of 1 year. METHODS:Forty-eight premenopausal women, attending our gynecology clinic with the complaint of menorrhagia, were en...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2005.12.005
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Potential barriers to intrauterine device (IUD) use include provider concern about difficult insertion, particularly for nulliparous women. OBJECTIVE:This study aims to evaluate the evidence on the effectiveness of medications to ease IUD insertion on provider outcomes (i.e., ease of insertion, need for adj...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/j.contraception.2016.06.014
更新日期:2016-12-01 00:00:00
abstract::Ethylene-vinyl acetate (EVA) polymeric contraceptive implants (Implanon) containing 3-keto-desogestrel have been prepared aiming at an in vitro initial release rate of 60 micrograms 3-keto-desogestrel/day. These implants are designed to have an intended life-time of 2 years. During a 3-year period, the release of thes...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(93)90093-m
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVES:The objective of the present study was to investigate the effect of vaginally and orally administered misoprostol on the local cervical inflammatory response. METHODS:Healthy women with a normal intrauterine pregnancy between 8 and 12 weeks of gestation presenting for an elective termination of pregnancy by...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.contraception.2005.02.012
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Hormonal contraception is the most common medication used by reproductive aged women but there is little understanding of the impact of hormonal contraception on obesity and metabolism. Adipokine levels (adiponectin, resistin) and markers of adipocyte development (DLK-1) are altered in obese animals and huma...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2012.10.029
更新日期:2013-07-01 00:00:00
abstract::High speed cinematography of latex condoms inflated to burst under standard (ISO) conditions reveals that rupture of the condom typically is initiated at a small focal point on the shank of the condom and then rapidly propagates throughout the condom's surface, often ending with partial or full severance of the condom...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(09)91004-6
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:Maternal trisomy 21 ovarian mosaicism might provide the major causative factor for fetal Down syndrome. The small proportion of trisomy 21 oocytes thought to be retarded in their maturation in comparison to normal disomic ones, and the maternal age effect can be based on an accumulation of trisomy 21 oocytes...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2012.08.040
更新日期:2013-04-01 00:00:00