Abstract：
:There is agreement that the relative risk of developing pelvic inflammatory disease (PID) increases among women who use the intrauterine contraceptive device (IUD). The role of Chlamydia in causing PID among IUD users is not clear. The present study demonstrates that Chlamydia trachomatis growth can be inhibited in cultured human endometrial cells by copper ions at concentrations known to be released by the copper IUDs. More than 98% inhibition was produced with 10(-5) and 10(-6) M of copper. Both C. trachomatis serovar E and a lymphogranuloma venereum Chlamydia serovar L2 (LGV) were inhibited by the copper ions. Although the mechanism of the inhibition is not known, the continuous presence of the copper ions during and after adherence appeared to be necessary for maximal effect. If such inhibition occurs in vivo, it is possible that copper ions released from the copper-containing IUD may partially protect against chlamydial infection.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Kleinman D,Sarov I,Insler Vdoi
10.1016/0010-7824(89)90041-3subject
Has Abstractpub_date
1989-06-01 00:00:00pages
665-76issue
6eissn
0010-7824issn
1879-0518pii
0010-7824(89)90041-3journal_volume
39pub_type
杂志文章相关文献
CONTRACEPTION文献大全abstract：:The metabolism of isotopically labeled ethinyl estradiol (EE) and mestranol (ME) was studied in 3 baboons before and after the simultaneous injection of a norethindrone-mestranol contraceptive formulation. 6 days after the administration of tritiated-EE and carbon-14-ME, the mean urinary excretion of labeled-EE was 3...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(77)90116-0
更新日期：1977-03-01 00:00:00
abstract：:Presumably, Latino women engage in little family planning because of religious or cultural objections to contraception. The purpose of this study was to examine how acculturation, religion and various demographic factors were related to the family-planning behaviors of Latino women in the United States. Data were coll...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2003.10.011
更新日期：2004-03-01 00:00:00
abstract：:The mechanism of action of intrauterine devices varies from one type of device to another, although the principle of action is the same, namely, to interfere with the physiology of reproduction at the endometrial level. The biochemical changes of the endometrial tissue and the composition of the uterine fluid have bee...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/0010-7824(87)90058-8
更新日期：1987-07-01 00:00:00
abstract：OBJECTIVE:To assess patterns of contraceptive use at last intercourse among women with physical or cognitive disabilities compared to women without disabilities. STUDY DESIGN:We analyzed responses to 12 reproductive health questions added by seven states to their 2013 Behavioral Risk Factor Surveillance System questio...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2017.12.008
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the initial safety and effectiveness of the intrauterine ball (IUB), a copper intrauterine device that, upon insertion in the uterus, takes a three-dimensional spherical form. STUDY DESIGN:Fifteen women were followed for 1 year, with follow-up visits at 1, 3, 6, 9 and 12 months. RESULTS:The phys...
journal_title：Contraception
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.contraception.2013.10.017
更新日期：2014-02-01 00:00:00
abstract：:A study was conducted to evaluate the effect of NORPLANT use on hemoglobin levels (HB), packed cell volume (PCV) and menstrual bleeding patterns. NORPLANT insertions were performed on 50 healthy volunteers in Ilorin, Nigeria, between January-March 1986. Whole blood samples were collected at admission, 6-month and 12-m...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(89)90059-0
更新日期：1989-03-01 00:00:00
abstract：:Chemical immersion tests, electrochemical methods and atomic absorption spectrometry were employed to investigate the corrosion behavior of Cu and the Cu-Zn-Al shape memory alloy (SMA) in simulated uterine fluid. The effect of pH on corrosion rate and corrosion potential was also investigated. The results indicated th...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2005.04.006
更新日期：2005-09-01 00:00:00
abstract：:A multicentre randomized clinical trial of the TCu220C, Lippes Loop D and Copper 7 was undertaken in nine WHO Collaborating centres for Clinical Research in Human Reproduction. A total of 984, 992 and 994 devices, respectively, were inserted between 1976 and 1978. The subjects were followed for two years. At this time...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0010-7824(82)90167-6
更新日期：1982-07-01 00:00:00
abstract：OBJECTIVES:To compare pain levels and medication needs after placement of laminaria vs Dilapan-S, and after dilation and evacuation (D&E). STUDY DESIGN:We conducted a single-blinded randomized control trial of patients undergoing D&E at 15 0/7 to 23 6/7 weeks gestation, randomizing to cervical preparation with laminar...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2020.11.014
更新日期：2020-12-04 00:00:00
abstract：OBJECTIVE:Our objective was to compare continuation and complication rates of subdermal etonogestrel implants and intrauterine devices (IUDs) using Medicaid insurance claims. STUDY DESIGN:We performed a retrospective cohort study using insurance claims data for 15- to 44-year-old subjects receiving implants or IUDs fr...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2018.04.012
更新日期：2018-04-24 00:00:00
abstract：:Combined oral contraceptives are undoubtedly popular. By the end of the 1980's, an estimated 63 million married women around the world were using this method of contraception. In Britain, perhaps 95% of all sexually active women have used the pill at some time before their 30th birthday. Commensurate with such widespr...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/0010-7824(95)00095-r
更新日期：1995-06-01 00:00:00
abstract：:A drug delivery system which provides a sustained release of norethindrone (NET) and mestranol (ME) for one month after a single intramuscular injection was assessed as a long-acting injectable contraceptive. The system is based upon well defined particle size crystals of the synthetic steroids maintained in suspensio...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(87)90051-5
更新日期：1987-01-01 00:00:00
abstract：:Because RU 486 synergizes with anordrin and its dihydroxylated metabolite to terminate established pregnancy in the rat and rabbit, the interactions of these agents were studied at two days postcoitally in the rat. RU 486 at a dose of 4 mg/kg did not prevent pregnancy when the animals were killed 12 days post insemina...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(93)90038-9
更新日期：1993-04-01 00:00:00
abstract：:Seventy-five women with a mean age of 27.5 years who requested Norplant implants for contraception were studied over a five-year period. The patients kept daily diaries of their vaginal bleeding and coital frequency, and were seen at least every six months at which time their weight was measured. This study examines t...
journal_title：Contraception
pub_type： 临床试验,杂志文章
doi：10.1016/0010-7824(94)90047-7
更新日期：1994-08-01 00:00:00
abstract：BACKGROUND:Emergency contraception (EC) does not always work. Clinicians should be aware of potential risk factors for EC failure. STUDY DESIGN:Data from a meta-analysis of two randomized controlled trials comparing the efficacy of ulipristal acetate (UPA) with levonorgestrel were analyzed to identify factors associat...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2011.02.009
更新日期：2011-10-01 00:00:00
abstract：:Forty-three homozygous (SS) female sickle cell anemic patients with a history of at least one painful crisis per month and desiring a reversible contraceptive were administered DMPA/3 months or Microgynon monthly. A third group of 16 surgically sterilized patients served as control. Patients were followed for 1 year t...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0010-7824(97)00156-x
更新日期：1997-11-01 00:00:00
abstract：:Ten Egyptian women who were using the injectable contraceptive norethisterone oenanthate (NET-OEN) for at least 6 months were monitored weekly for a period of 12 weeks by measuring 3 pituitary hormones (FSH, LH and prolactin) and 2 ovarian hormones (oestradiol 17-B and progesterone). It was concluded that NET-OEN is a...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(83)80004-3
更新日期：1983-07-01 00:00:00
abstract：:Mifepristone-induced abortion is increasingly common. Recent alerts have highlighted the occurrence of infrequent but serious complications. We report a case of serious bacterial infection after medical termination that occurred in the absence of the usual signs of infection. ...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2005.09.003
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVES:We wanted to explore the effects of two different low doses (0.5μM and 0.05μM) of mifepristone, exposed during the receptive period, on the human embryo implantation process, using a well-established three-dimensional in vitro cell culture model, specifically developed to study this process. METHODS:An in v...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2016.03.009
更新日期：2016-08-01 00:00:00
abstract：:Blood pyrodoxine hydrochloride (vitamin-B6) concentration was determined in 50 women using combined oral contraceptives (OCs), 24 women who received an intramuscular injection of 150 mg medroxyprogesterone acetate (MPA) every 12 weeks, and in 14 women who used an intrauterine device (IUD) at the out-patient contracep...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(74)90078-x
更新日期：1974-04-01 00:00:00
abstract：:The opinions of 20 international experts in reproductive endocrinology and family planning service delivery were solicited concerning contraceptive pill use during breastfeeding and, in particular, to determine whether the experts felt that breastfeeding women who use progestin-only pills (POPs) should be advised to s...
journal_title：Contraception
pub_type： 社论
doi：10.1016/0010-7824(95)00076-m
更新日期：1995-05-01 00:00:00
abstract：BACKGROUND:The purpose of this pilot project was to test the feasibility of a technique designed to place a copper intrauterine device (IUD) through the hysterotomy incision of an elective cesarean delivery to minimize possible contamination and to guarantee that tailstrings were visible in the vagina for easy removal ...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2009.01.014
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVES:To assess factors associated with routine pregnancy intention screening by primary care physicians and their support for such an initiative. STUDY DESIGN:We conducted a cross-sectional survey study of 443 primary care physicians in New York State. We performed multivariable logistic regression analyses of p...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2019.11.004
更新日期：2020-02-01 00:00:00
abstract：:Intramuscular administration of STS 557 (17 alpha C-cyanomethyl-17 beta-hydroxy-estra-4,9(10)-diene-3-one) at a daily dose of 12 mg/monkey for 8 weeks induced severe oligospermia to complete azoospermia by the 9th week of initiation of treatment with concomitant decrease in the serum level of testosterone. The sperm m...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(88)90009-1
更新日期：1988-06-01 00:00:00
abstract：:Data from published studies of the quantity of medroxyprogesterone acetate and/or its metabolites in the milk of lactating women receiving Depo-Provera for contraception is extrapolated into the amount of drug ingested daily by a theoretically average infant. Comparisons are made with the results of similar studies in...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/0010-7824(81)90027-5
更新日期：1981-04-01 00:00:00
abstract：:A cross-sectional descriptive study on knowledge, attitudes, and practice about emergency contraception (EC) was conducted among nurses and nursing students using a self-administered questionnaire. One-hundred-sixty-seven qualified nurses and 63 nursing students completed the questionnaire. Over 95% listed at least on...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(99)00023-2
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:This study estimates how making oral contraceptive pills (OCPs) available without a prescription may affect contraceptive use, unintended pregnancies and associated contraceptive and pregnancy costs among low-income women. STUDY DESIGN:Based on published figures, we estimate two scenarios [low over-the-count...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2015.01.010
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Rural-to-urban migrant women in Shanghai have poor reproductive health; the incidence of postpartum unintended pregnancy and contraceptive practices has not been adequately studied in this population. STUDY DESIGN:This retrospective study examined the incidence of postpartum unintended pregnancy and associa...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2012.05.007
更新日期：2012-12-01 00:00:00
abstract：:Introduction of the birth control pill in the United States in 1960 marked the end of a relatively short period of time (< 10 years) to intentionally produce an oral contraceptive, and the beginning of a relatively long period of controversy surrounding the use of the pill. Availability of the pill had an impact on va...
journal_title：Contraception
pub_type： 历史文章,杂志文章
doi：10.1016/s0010-7824(98)00131-0
更新日期：1999-01-01 00:00:00
abstract：:The comparative in vitro spermicidal effects of (+)-gossypol, (-)-gossypol and (+/-)-gossypol were evaluated on the spermatozoa of human, monkey, rabbit, mouse, rat and hamster. The spermicidal effects of gossypol isomers were also compared with those of gossypolone, which is a proposed major metabolite of gossypol. G...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(84)90088-x
更新日期：1984-09-01 00:00:00
