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Interval iud insertion in parous women: a randomized multicentre comparative trial of the Lippes Loop D, TCu220c and the Copper 7.

Abstract：

:A multicentre randomized clinical trial of the TCu220C, Lippes Loop D and Copper 7 was undertaken in nine WHO Collaborating centres for Clinical Research in Human Reproduction. A total of 984, 992 and 994 devices, respectively, were inserted between 1976 and 1978. The subjects were followed for two years. At this time 18,743, 17,013 and 17,927 woman-months experience had been accumulated with each device, respectively. The Lippes Loop consistently failed to perform as well as the TCu220C regardless of age or parity. The TCu220C had statistically significantly lower pregnancy rates at one and two years of use than either of the other two devices as well as lower expulsion rates. The TCu220C had lower removal rates at one and two years than the Lippes Loop and Copper 7. At one and two years the TCu220C had significantly higher continuation rates than the other two devices. It is concluded that the TCu220C is the device of choice amongst the three devices studied. :A multicenter, randomized, clinical trial of the TCu220C, Lippes Loop D, and Copper 7 was undertaken in 9 World Health Organization Collaborating Centers for Clinical Research in Human Reproduction. A total of 984 TCu220, 992 Lippes Loop D, 994 Copper 7 devices were inserted between 1976-78. The subjects were followed for 2 years. 18,743(TCu220C), 17,013(Lippes Loop D), and 17,927(Copper 7) woman-months experience were accumulated with each device. The TCu220C had statistically significantly lower pregnancy and expulsion rates at 1 and 2 years of use than either of the other 2 devices. Overall the TCu220C had lower removal rates at 1 and 2 years than the Lippes Loop and Copper 7; however, the TCu220C and Copper 7 had higher rates for nonmedical removals than the Lippes Loop D. At 1 and 2 years, the TCu220C had significantly higher continuation rates than the other 2 devices which had similar perforance records. It is concluded that the TCu220C is the device of choice among the 3 devices studied.

journal_name

Contraception

journal_title

Contraception

authors

doi

10.1016/0010-7824(82)90167-6

subject

Has Abstract

pub_date

1982-07-01 00:00:00

pages

1-22

issue

eissn

0010-7824

issn

1879-0518

pii

0010-7824(82)90167-6

journal_volume

pub_type

临床试验,杂志文章,随机对照试验

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Interval iud insertion in parous women: a randomized multicentre comparative trial of the Lippes Loop D, TCu220c and the Copper 7.