Abstract:
:To elucidate the role of (1-->3)-beta-D-glucan in pulmonary aspergilloma, serum concentrations of (1-->3)-beta-D-glucan were measured repeatedly for as long as 10 months in eight patients. In four patients with inactive disease, concentrations of (1-->3)-beta-D-glucan were in the normal range.The concentrations of (1-->3)-beta-D-glucan increased in two patients, although the disease was inactive. This increase might show the earliest stage of the invasive process of the disease. In two other patients with active disease, (1-->3)-beta-D-glucan increased. Other parameters, such as galactomannan, immunodiffusion and a radio-allergosorbent test, as well as inflammatory m arkers such as C-reactive protein and the leukocyte count, did not show any consistent tendency in regard to the activity of the disease. Thus, a (1-->3)-beta-D-glucan assay may add valuable data for evaluating the disease activity and understanding the disease process of pulmonary aspergilloma.
journal_name
Mediators Inflammjournal_title
Mediators of inflammationauthors
Yuasa K,Goto Hdoi
10.1080/09629359791631subject
Has Abstractpub_date
1997-01-01 00:00:00pages
285-7issue
4eissn
0962-9351issn
1466-1861journal_volume
6pub_type
杂志文章abstract::The aim of the study was to evaluate the role of Smad3, Smad7, and TGF-β1 in intrauterine adhesion (IUA) patients and experimental rabbit models. 60 IUA patients, 30 control participants, and 18 female rabbits were enrolled in this study. We found that the plasma concentrations and protein expressions of TGF-β1 were s...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2016/4158287
更新日期:2016-01-01 00:00:00
abstract::Invertebrates do not display the level of sophistication in immune reactivity characteristic of mammals and other 'higher' vertebrates. Their great number and diversity of forms, however, reflect their evolutionary success and hence they must have effective mechanisms of defence to deal with parasites and pathogens an...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/S0962935196000014
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abstract:BACKGROUND:We have previously reported a continuous activation of caspase-1 and increased interleukin (IL)-1β levels in early rheumatoid arthritis (RA). These observations raised the hypothesis that drugs targeting the IL-1β pathway, in addition to tumour necrosis factor (TNF), may be particularly effective for early R...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2014/195327
更新日期:2014-01-01 00:00:00
abstract::Interleukin-5 (IL-5) is a cytokine that preferentially effects the development and function of eosinophils, and is considered important in the pathophysiology of allergic inflammation. In this study, we evaluated the ability of recombinant human IL-5 (rHu IL-5) to promote tissue eosinophilia and the importance of this...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/S0962935195000536
更新日期:1995-01-01 00:00:00
abstract::The increased morbidity, mortality, and ineffective treatment associated with the pathogenesis of chronic inflammatory diseases such as asthma and chronic obstructive pulmonary disease (COPD) have generated much research interest. The key role is played by phospholipases from the A2 superfamily: enzymes which are invo...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2013/793505
更新日期:2013-01-01 00:00:00
abstract::Procalcitonin (PCT) is one of the best diagnostic and prognostic markers in clinical practice, widely used to evaluate the evolution of bacterial infections. Although it is mainly produced by thyroid, during sepsis almost all the peripheral tissues are involved in PCT production. Parenchymal cells have been suggested ...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2014/248963
更新日期:2014-01-01 00:00:00
abstract::Rheumatoid arthritis (RA), a chronic inflammatory disease usually occurring in synovial tissues and joints, is highly associated with genetic and environmental factors. ORAI1, a gene related to cellular immune system, has been shown to be involved in the pathogenesis of chronic inflammatory diseases and immune disease...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2014/834831
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Asthma is a disorder characterized by a predominance of Th2 cells and eosinophilic inflammation. Suppressors of cytokine signaling (SOCS) proteins act as negative regulators of cytokine signaling. In particular, SOCS1 and SOCS3 play an important role in immune response by controlling the balance between Th1 ...
journal_title:Mediators of inflammation
pub_type: 杂志文章
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更新日期:2011-01-01 00:00:00
abstract::Behçet's disease (BD) is a multisystemic disorder of unknown etiology characterized by the "triple symptom complex" consisting of recurrent oral aphthosis, genital ulcers, and chronic relapsing bilateral uveitis. Recurrent mucocutaneous lesions are generally considered the hallmark of the disease, being the most commo...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2015/451675
更新日期:2015-01-01 00:00:00
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journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1080/09629350050024339
更新日期:2000-01-01 00:00:00
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journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/S0962935193000341
更新日期:1993-01-01 00:00:00
abstract::Gout is a common inflammatory disease characterized by acute arthritis and hyperuricemia. A number of epidemiological studies have suggested the critical role of gout in carcinogenesis. The aim of this study was to estimate the association between gout and cancer risk by meta-analysis of all relevant studies published...
journal_title:Mediators of inflammation
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2015/680853
更新日期:2015-01-01 00:00:00
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journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2015/460125
更新日期:2015-01-01 00:00:00
abstract::This study investigated the protective effects of intravitreal Resolvin D1 (RvD1) against LPS-induced rat endotoxic uveitis (EIU). RvD1 was administered into the right eye at a single injection of 5 μL volume containing 10-100-1000 ng/kg RvD1 1 h post-LPS injection (200 μg, Salmonella minnesota) into thefootpad of Spr...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2015/149381
更新日期:2015-01-01 00:00:00
abstract::Inflammatory mediators play a critical role in ulcerative colitis immune and inflammatory processes. The aim of the study was to investigate the effects of Ginkgo biloba extract on inflammatory mediators (SOD, MDA, TNF-alpha, NF-kappaBp65, IL-6) in TNBS-induced colitis in rats. Colitis in rats was induced by colonic a...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/MI/2006/92642
更新日期:2006-01-01 00:00:00
abstract::There is some anecdotal evidence that oxygen-ozone therapy may be beneficial in some human diseases. However so far only a few biochemical and pharmacodynamic mechanisms have been elucidated. On the basis of preliminary data we postulated that controlled ozone administration would promote an oxidative preconditioning ...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1080/09629359890983
更新日期:1998-01-01 00:00:00
abstract::Chronic inflammation is a hallmark of HIV infection. Eicosanoids reflect inflammation, oxidant stress, and vascular health and vary by sex and metabolic parameters. Raltegravir (RAL) is an HIV-1 integrase inhibitor that may have limited metabolic effects. We assessed urinary F2-isoprostanes (F2-IsoPs), prostaglandin E...
journal_title:Mediators of inflammation
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/803095
更新日期:2014-01-01 00:00:00
abstract::Modification of endogenous eicosanoid synthesis by dietary n-3 fatty acid supplementation reduces febrile responses, but the mechanisms underlying these effects in vivo have not been determined. In the present study, local inflammation was induced by intramuscular injection ofturpentine in rats fed control or n-3 supp...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/S0962935194000499
更新日期:1994-01-01 00:00:00
abstract::Since iron can contribute to detrimental radical generating processes through the Fenton and Haber-Weiss reactions, it seems to be a reasonable approach to modulate iron-related pathways in inflammation. In the human organism a counterregulatory reduction in iron availability is observed during inflammatory diseases. ...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2015/516740
更新日期:2015-01-01 00:00:00
abstract::Shinbaro3, a formulation derived from the hydrolysed roots of Harpagophytum procumbens var. sublobatum (Engl.) Stapf, has been clinically used in the pharamacopuncture treatment of arthritis in Korea. In the present study, Shinbaro3 inhibited NO generation in LPS-induced RAW 264.7 cells in a dose-dependent manner. Shi...
journal_title:Mediators of inflammation
pub_type: 杂志文章,收录出版
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更新日期:2018-04-05 00:00:00
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journal_title:Mediators of inflammation
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:Mediators of inflammation
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
abstract::Trypanosoma cruzi infection was studied in mouse lines selected for maximal (AIRmax) or minimal (AIRmin) acute inflammatory reaction and for high (HIII) or low (LIII) antibody (Ab) responses to complex antigens. Resistance was associated with gender (females) and strain-the high responder lines AIRmax and HIII were re...
journal_title:Mediators of inflammation
pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
abstract::Lysophosphatidic acid (LPA) is a bioactive phospholipid playing an important role in various inflammatory diseases by inducing expression and secretion of many inflammatory cytokines/chemokines. Here we report in a murine air pouch model of inflammation that LPA induced CXCL13 secretion in a time-dependent manner and ...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2015/248492
更新日期:2015-01-01 00:00:00
abstract::Periodontitis (PD) and rheumatoid arthritis (RA) are immunoinflammatory diseases where leukocyte infiltration and inflammatory mediators induce alveolar bone loss, synovitis, and joint destruction, respectively. Thus, we reviewed the relationship between both diseases considering epidemiological aspects, mechanical pe...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2015/259074
更新日期:2015-01-01 00:00:00
abstract::Interleukin-33 (IL-33) is associated with the development of Th2 responses. This study examined the potential role of IL-33 in the pathogenic process of chronic hepatitis C (CHC) in Chinese patients. The levels of serum IL-33 and sST2 in 154 patients with CHC, 24 with spontaneously resolved HCV (SR-HCV) infection and ...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2012/819636
更新日期:2012-01-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is considered a multifactorial, multisystem disease in which inflammation and the immune system play important roles in development and progression. The pleiotropic cytokine TNFα is one of the major players governing the inflammation in the central nervous system and peripheral dist...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2017/2985051
更新日期:2017-01-01 00:00:00
abstract::To evaluate the impact of low levels of high density lipoprotein cholesterol (HDL-c) on patients with LDL-c average levels, focusing on oxidative, lipidic, and inflammatory profiles. Patients with cardiovascular risk factors (n = 169) and control subjects (n = 73) were divided into 2 subgroups, one of normal HDL-c and...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2013/612038
更新日期:2013-01-01 00:00:00
abstract::The mixed leukocyte population obtained from the peritoneum of the August rat is a potentially important experimental model of inherent eosinophilia that has not been well characterized. In the present study, isolated cell preparations generated a concentration-dependent release of leukotriene (LT) C(4) when exposed t...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/S0962935196000610
更新日期:1996-01-01 00:00:00
abstract::Endothelial dysfunction is regarded as an important factor in the pathogenesis of vascular disease in obesity-related type 2 diabetes. The imbalance in repair and injury (hyperglycemia, hypertension, dyslipidemia) results in microvascular changes, including apoptosis of microvascular cells, ultimately leading to diabe...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2010/792393
更新日期:2010-01-01 00:00:00