Transforming growth factor-beta overexpression in cutaneous extramedullary hematopoiesis of a patient with myelodysplastic syndrome associated with myelofibrosis.

abstract：BACKGROUND:Some studies have purported to link isotretinoin prescribed for acne with the development of inflammatory bowel disease (IBD). OBJECTIVE:We sought to identify existence of disproportionate attorney-initiated reporting of isotretinoin-associated IBD in the Food and Drug Administration Adverse Event Reporting...

journal_title：Journal of the American Academy of Dermatology

authors： Stobaugh DJ,Deepak P,Ehrenpreis ED

更新日期：2013-09-01 00:00:00

abstract：:A screening program for antiviral drugs begun at Burroughs Wellcome in the 1960s resulted in the discovery of acyclovir in 1974. Preclinical investigation brought the drug to clinical trials in 1977 and the first form of the drug (topical) was available to physicians in 1982. Activity of acyclovir is greatest against ...

journal_title：Journal of the American Academy of Dermatology

authors： King DH

更新日期：1988-01-01 00:00:00

abstract：:A recent familial case of hereditary epidermolytic palmoplantar keratoderma (Vörner type) that was treated with orally administered etretinate is reported herein. A review of the literature with regard to the clinical, genetic, and laboratory features of this rare genodermatosis is also presented. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kanitakis J,Tsoitis G,Kanitakis C

更新日期：1987-09-01 00:00:00

abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

journal_title：Journal of the American Academy of Dermatology

authors： Lober CW

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Many patients who give a history of a dermatitis reaction to jewelry or metal contact with skin are negative to metals on standard patch testing. Some may be showing false-negative reactions. OBJECTIVE:Our purpose was to determine whether patients with a history of jewelry reactions but whose standard patch...

journal_title：Journal of the American Academy of Dermatology

authors： Gawkrodger DJ,Lewis FM,Shah M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:A wide array of miscellaneous agents is being studied for the treatment of atopic dermatitis (AD), including targeted topical, oral systemic, and biologic agents. OBJECTIVE:To review the known efficacy and safety to date for such agents being studied for the treatment of AD. METHODS:A nonsystematic review ...

journal_title：Journal of the American Academy of Dermatology

authors： Vakharia PP,Silverberg JI

更新日期：2018-03-01 00:00:00

abstract：:Retinoids, synthetic vitamin A analogs, stimulate mucous metaplasia and gap-junction proliferation in embryonic and neoplastic epidermis. Such effects demonstrate that vitamin A has potent effects on epidermal differentiation. Oddly, however, retinoid action in normal postnatal tissues, where these drugs are used clin...

journal_title：Journal of the American Academy of Dermatology

authors： Elias PM

更新日期：1986-10-01 00:00:00

abstract：:POEMS syndrome is an unusual plasma cell dyscrasia with multisystemic manifestations featuring polyneuropathy, organomegaly, endocrinopathy, M protein and constant skin involvement. We have seen a 58-year-old white man presenting with generalized eruptive angiomas as a rare skin manifestation of this syndrome. We revi...

journal_title：Journal of the American Academy of Dermatology

authors： Puig L,Moreno A,Domingo P,Llistosella E,de Moragas JM

更新日期：1985-05-01 00:00:00

abstract：:We performed a 22-month trial of topical tretinoin (retinoic acid) in the treatment of photoaging. Thirty patients participated in a 4-month, randomized, blinded, vehicle-controlled study that has been reported previously; 21 patients continued tretinoin therapy on an open-label basis, participating in the study for a...

journal_title：Journal of the American Academy of Dermatology

authors： Ellis CN,Weiss JS,Hamilton TA,Headington JT,Zelickson AS,Voorhees JJ

更新日期：1990-10-01 00:00:00

abstract：:Histoplasma capsulatum and Trichosporon inkin may cause disseminated disease in immunocompromised patients. Disseminated T inkin, the causative agent of white piedra, is rare and difficult to diagnose. We report the case of a 28 year-old man with newly diagnosed HIV infection who developed asymptomatic lesions on his ...

journal_title：Journal of the American Academy of Dermatology

authors： David C,Martin DB,Deng A,Cooper JZ

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Trichoadenoma is a rare benign follicular tumor first described by Nikolowski 50 years ago. Both trichoadenoma and desmoplastic trichoepithelioma are composed of cords of epithelial cells and cornifying cysts embedded in sclerotic stroma. In trichoadenoma the cystic component predominates, while desmoplastic...

journal_title：Journal of the American Academy of Dermatology

authors： Shimanovich I,Krahl D,Rose C

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis/eczema (AD/E) is a common disease. Few studies have attempted to quantify the cost to third-party payers. OBJECTIVE:Our purpose was to identify the annual cost of medical services and prescription drugs for the treatment of AD/E to private insurance and Medicaid payers in the United States...

journal_title：Journal of the American Academy of Dermatology

authors： Ellis CN,Drake LA,Prendergast MM,Abramovits W,Boguniewicz M,Daniel CR,Lebwohl M,Stevens SR,Whitaker-Worth DL,Cheng JW,Tong KB

更新日期：2002-03-01 00:00:00

abstract：:Glyceryl monothioglycolate has recently been implicated as an allergen. A case of a hairdresser who used this material is presented. He appeared to have an irritant contact dermatitis on his fingertips. Patch testing the patient and extensive patch testing in a group of fifty-four volunteers showed a very high inciden...

journal_title：Journal of the American Academy of Dermatology

authors： Rapaport M

更新日期：1983-11-01 00:00:00

abstract：:This report describes a 25-year-old white woman with lentigines, cutaneous myxomas, bilateral atrial myxomas, and cerebral artery aneurysms. We believe this case to be the fifth reported case of this unusual association in the medical literature, with the additional finding of a central nervous system aneurysm. In the...

journal_title：Journal of the American Academy of Dermatology

authors： Reed OM,Mellette JR Jr,Fitzpatrick JE

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:The efficacy of the skin self-examination (SSE) to detect artificial changes in the size of nevi has not been evaluated in a controlled setting. OBJECTIVE:Our purpose was to determine the sensitivity and specificity of the SSE in detecting artificial changes in mole size in patients at high risk for melanom...

journal_title：Journal of the American Academy of Dermatology

authors： Muhn CY,From L,Glied M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:The association of human herpesvirus 6 (HHV-6) and HHV-7 with pityriasis rosea suggests that systemic drugs directed against HHV may hasten recovery of patients with pityriasis rosea. OBJECTIVE:The purpose of this study was to verify the efficacy of oral acyclovir in the treatment of pityriasis rosea. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Drago F,Vecchio F,Rebora A

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Biologic agents may predispose patients to skin and soft tissue infections (SSTIs). Guidelines recommend discontinuing the agent pre-operatively; the true risk of infection is unclear. OBJECTIVES:To assess the incidence of SSTIs in patients on biologic agents for all clinical indications. A secondary aim is...

journal_title：Journal of the American Academy of Dermatology

authors： Nguyen ED,Gabel CK,Kroshinsky D

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Dermatoscopy is the most commonly used noninvasive tool for the diagnosis of pigmented skin lesions, but few studies have investigated the value of cytology in the identification of those lesions. OBJECTIVE:We compared the accuracy of dermatoscopy with that of the Tzanck smear test in the diagnosis of pigme...

journal_title：Journal of the American Academy of Dermatology

authors： Durdu M,Baba M,Seçkin D

更新日期：2011-11-01 00:00:00

abstract：:The epidermal nevus syndrome is characterized by the association of epidermal nevi with abnormalities of the skin, skeletal system, central nervous system, eyes, and cardiovascular system, as well as with malignant conditions. We describe a 2-year-old girl with an extensive epidermal nevus involving the left side of t...

journal_title：Journal of the American Academy of Dermatology

authors： Tay YK,Weston WL,Ganong CA,Klingensmith GJ

更新日期：1996-11-01 00:00:00

abstract：:Clofazimine has been in clinical use for almost 40 years, but little is known of its mechanism of action. The primary indication for clofazimine is multibacillary leprosy, but it is useful in several infectious and noninfectious diseases, such as typical myocobacterial infections, rhinoscleroma, pyoderma gangrenosum, ...

journal_title：Journal of the American Academy of Dermatology

authors： Arbiser JL,Moschella SL

更新日期：1995-02-01 00:00:00

abstract：:Squamous cell carcinoma on sun-damaged skin is a malignant neoplasm that evolves from its inception as squamous cell carcinoma in situ, which is commonly referred to as an actinic keratosis. In this study, we reviewed 1011 squamous cell carcinomas on sun-damaged skin and found that nearly 100% of these lesions contain...

journal_title：Journal of the American Academy of Dermatology

authors： Guenthner ST,Hurwitz RM,Buckel LJ,Gray HR

更新日期：1999-09-01 00:00:00

abstract：:Lymphocyte function as expressed by T-lymphocyte subsets and natural killer cell activity was evaluated in a group of Israeli patients with classic Kaposi's sarcoma. T-cell subsets were examined in 28 patients, 14 with lesions limited to the lower extremities and 14 with diffuse cutaneous or systemic involvement. CD4 ...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman-Birnbaum R,Weltfriend S,Pollack S

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Early recognition of melanoma is the key in preventing metastatic disease. OBJECTIVE:The aim of this study was to evaluate diagnostic ability of general practitioners (GPs) and dermatologists concerning pigmented skin lesions in general and melanoma in particular. We also investigated whether the diagnostic...

journal_title：Journal of the American Academy of Dermatology

authors： Brochez L,Verhaeghe E,Bleyen L,Naeyaert JM

更新日期：2001-06-01 00:00:00

abstract：:With the introduction of the Medicare Access and Children's Health Insurance Program Reauthorization Act, clinicians who are not eligible for an exemption must choose to participate in 1 of 2 new reimbursement models: the Merit-based Incentive Payment System or Alternative Payment Models (APMs). Although most dermatol...

journal_title：Journal of the American Academy of Dermatology

authors： Barbieri JS,Miller JJ,Nguyen HP,Forman HP,Bolognia JL,VanBeek MJ,Group for Research of Policy Dynamics in Dermatology.

更新日期：2017-06-01 00:00:00

abstract：:Treatment of cicatricial pemphigoid is a problem because patients afflicted are elderly, the disease is chronic, systemic agents required for control are potentially toxic (particularly to older patients), and the disease is often in an advanced stage when the diagnosis is established and requires aggressive therapy f...

journal_title：Journal of the American Academy of Dermatology

authors： Rogers RS 3rd,Seehafer JR,Perry HO

更新日期：1982-02-01 00:00:00

abstract：:Two babies were found to have large hemangiomas. Histologically there were many islands of compactly packed mesenchymal cells in the deep dermis and subcutaneous tissue. Electron microscopically there was proliferation of immature endothelial cells and pericytes. Characteristic crystalline lamellae were in the endothe...

journal_title：Journal of the American Academy of Dermatology

authors： Kumakiri M,Muramoto F,Tsukinaga I,Yoshida T,Ohura T,Miura Y

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Sézary syndrome is a cutaneous T-cell lymphoma characterized by erythroderma and leukemic involvement. OBJECTIVE:We sought to define the clinical, biologic, and histopathologic features of Sézary syndrome without erythroderma. METHODS:Features of patients with Sézary syndrome and normal-appearing skin or s...

journal_title：Journal of the American Academy of Dermatology

authors： Henn A,Michel L,Fite C,Deschamps L,Ortonne N,Ingen-Housz-Oro S,Marinho E,Beylot-Barry M,Bagot M,Laroche L,Crickx B,Maubec E

更新日期：2015-06-01 00:00:00

abstract：:When treating psoriasis, various topical emollients exist that can affect the penetration of ultraviolet radiation in phototherapy. Compared with normal-appearing skin with a reflectance of 4% to 5%, psoriatic skin has higher reflectance as a result of its increased air-to-corneocyte interfaces. Studies have tested th...

journal_title：Journal of the American Academy of Dermatology

authors： Asztalos ML,Heller MM,Lee ES,Koo J

更新日期：2013-05-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Despite improvements in melanoma mortality, disparities in melanoma survival persist. We evaluated possible sociodemographic and health care-based predictors of differences in melanoma survival in the United States by using the melanoma mortality-to-incidence ratio (MIR). METHODS:State-based MIRs were calcu...

journal_title：Journal of the American Academy of Dermatology

authors： Hopkins ZH,Moreno C,Carlisle R,Secrest AM

更新日期：2019-05-01 00:00:00