Abstract:
:Studies of the malignant potential of oral lichen planus (OLP) have been hampered by inconsistencies in the diagnostic criteria used for OLP, the criteria adopted to identify a true case of malignant transformation in OLP, the risk factors for malignant transformation and the optimum management of patients to ensure the early diagnosis of transformation. Consensus remains elusive, and leading workers in this field have recently published conflicting reports on the malignant potential of OLP and on the important question of the advisability of excluding patients with epithelial dysplasia or a tobacco habit from studies on this issue. The present review outlines these debates and proposes a possible a molecular basis for the malignant transformation in this disease.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Gonzalez-Moles MA,Scully C,Gil-Montoya JAdoi
10.1111/j.1601-0825.2008.01441.xsubject
Has Abstractpub_date
2008-04-01 00:00:00pages
229-43issue
3eissn
1354-523Xissn
1601-0825pii
ODI1441journal_volume
14pub_type
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