Oral lichen planus: controversies surrounding malignant transformation.

Abstract:

:Studies of the malignant potential of oral lichen planus (OLP) have been hampered by inconsistencies in the diagnostic criteria used for OLP, the criteria adopted to identify a true case of malignant transformation in OLP, the risk factors for malignant transformation and the optimum management of patients to ensure the early diagnosis of transformation. Consensus remains elusive, and leading workers in this field have recently published conflicting reports on the malignant potential of OLP and on the important question of the advisability of excluding patients with epithelial dysplasia or a tobacco habit from studies on this issue. The present review outlines these debates and proposes a possible a molecular basis for the malignant transformation in this disease.

journal_name

Oral Dis

journal_title

Oral diseases

authors

Gonzalez-Moles MA,Scully C,Gil-Montoya JA

doi

10.1111/j.1601-0825.2008.01441.x

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

229-43

issue

3

eissn

1354-523X

issn

1601-0825

pii

ODI1441

journal_volume

14

pub_type

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