Abstract:
OBJECTIVE:The present study aimed to summarize and update the evidence regarding the association between periodontitis and psoriasis. METHODS:The present systematic review was conducted under the guidelines of Transparent Reporting of Systematic Reviews and Meta-Analyses (PRISMA) and was recorded in the PROSPERO database, under registration number CRD42017063799. Three databases (MEDLINE, Embase, and Cochrane Library) were searched up to March 2020. Case-control or cohort studies assessing the association between periodontitis and psoriasis were identified. Quantitative synthesis was conducted with meta-analysis. RESULTS:A total of 13 studies (11 case-control and two cohort studies) assessing the association between periodontitis and psoriasis were included. Of these 13 articles, 9 showed the prevalence of periodontitis or psoriasis. Therefore, meta-analyses were conducted with data retrieved from the nine studies included. Pooled effect estimate for nine studies showed that patients with periodontitis associated with a higher risk of psoriasis with a pooled OR of 2.87 (95% CI, 1.75-4.69). CONCLUSIONS:This systematic review demonstrated a positive association between periodontitis and psoriasis; however, a causal relationship cannot be established. Due to the weak evidence, caution should be taken when interpreting the results regarding periodontal parameters. Well-designed prospective studies are necessary to evaluate interactions between both diseases.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Zhang X,Gu H,Xie S,Su Ydoi
10.1111/odi.13617subject
Has Abstractpub_date
2020-08-27 00:00:00eissn
1354-523Xissn
1601-0825pub_type
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