The association between serum 25-hydroxyvitamin D levels and dental caries in US adults.

Abstract:

OBJECTIVES:We investigated whether 25-hydroxyvitamin D concentration is independently associated with dental caries among adults in the United States. SUBJECTS AND METHODS:This investigation was a cross-sectional study. A total of 4,244 participants (aged 20-80 years) were enrolled through the 2007-2008 National Health and Nutrition Examination Survey (NHANES). Serum 25-hydroxyvitamin D was categorized into four groups based on previous studies: normal (≥75 nmol/ml), insufficient (50-74.9 nmol/ml), deficient (25-49.9 nmol/ml), and severely deficient (<25 nmol/ml). The dependent and independent variables included dental caries and serum 25-hydroxyvitamin D, respectively. The data were analyzed using univariate analyses, multivariable-adjusted analyses, and subgroup analyses. RESULTS:The fully adjusted model showed that 25-hydroxyvitamin D levels were negatively associated with dental caries after adjusting for the confounders (OR = 0.93, 95% CI 0.89 to 0.98). Compared with the normal group, the likelihood of dental caries was 2.48, 1.29, and 1.43 times higher in the severely deficient, deficient, and insufficient groups, respectively. CONCLUSIONS:Our findings suggest that serum 25-hydroxyvitamin D levels are significantly associated with the occurrence of dental caries among US adults.

journal_name

Oral Dis

journal_title

Oral diseases

authors

Zhou F,Zhou Y,Shi J

doi

10.1111/odi.13360

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

1537-1547

issue

7

eissn

1354-523X

issn

1601-0825

journal_volume

26

pub_type

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