Abstract:
OBJECTIVES:We investigated whether 25-hydroxyvitamin D concentration is independently associated with dental caries among adults in the United States. SUBJECTS AND METHODS:This investigation was a cross-sectional study. A total of 4,244 participants (aged 20-80 years) were enrolled through the 2007-2008 National Health and Nutrition Examination Survey (NHANES). Serum 25-hydroxyvitamin D was categorized into four groups based on previous studies: normal (≥75 nmol/ml), insufficient (50-74.9 nmol/ml), deficient (25-49.9 nmol/ml), and severely deficient (<25 nmol/ml). The dependent and independent variables included dental caries and serum 25-hydroxyvitamin D, respectively. The data were analyzed using univariate analyses, multivariable-adjusted analyses, and subgroup analyses. RESULTS:The fully adjusted model showed that 25-hydroxyvitamin D levels were negatively associated with dental caries after adjusting for the confounders (OR = 0.93, 95% CI 0.89 to 0.98). Compared with the normal group, the likelihood of dental caries was 2.48, 1.29, and 1.43 times higher in the severely deficient, deficient, and insufficient groups, respectively. CONCLUSIONS:Our findings suggest that serum 25-hydroxyvitamin D levels are significantly associated with the occurrence of dental caries among US adults.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Zhou F,Zhou Y,Shi Jdoi
10.1111/odi.13360subject
Has Abstractpub_date
2020-10-01 00:00:00pages
1537-1547issue
7eissn
1354-523Xissn
1601-0825journal_volume
26pub_type
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