Abstract:
OBJECTIVE:To investigate the sex differences in clinical features, including salivary flow rate, psychological distress and hypothalamic-pituitary-adrenal axis response and their inter-relationships in patients with burning mouth syndrome. SUBJECTS AND METHODS:Eighteen men and 37 postmenopausal women with burning mouth syndrome underwent a comprehensive questionnaire evaluation, psychological evaluation and salivary flow rate measurement. Laboratory tests were performed to investigate the function and integrity of the hypothalamic-pituitary-adrenal axis. RESULTS:Both unstimulated and stimulated salivary flow rates were higher in men than in women (unstimulated: 0.58 ± 0.32 vs. 0.37 ± 0.15 ml/min, p < .01; stimulated: 1.83 ± 0.63 vs. 1.22 ± 0.31, p < .001). Symptom severity scored on a visual analogue scale negatively correlated with anti-diuretic hormone levels in both sexes. The visual analogue scale scores negatively correlated with unstimulated (r = -.652, p < .01) and stimulated (r = -.376, p < .05) salivary flow rates in men and women, respectively. Unstimulated salivary flow rates positively correlated with anti-diuretic hormone (r = .453, p < .05) and progesterone (r = .402, p < .05) levels only in women. CONCLUSIONS:Our results suggest that clinicians should consider hypothalamic-pituitary-adrenal axis response, as well as sex and salivary flow rates, when identifying the aetiology of patients with burning mouth syndrome, as it may enable more accurate and effective treatment.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Lee YH,An JS,Chon Sdoi
10.1111/odi.13195subject
Has Abstractpub_date
2019-11-01 00:00:00pages
1983-1994issue
8eissn
1354-523Xissn
1601-0825journal_volume
25pub_type
杂志文章相关文献
ORAL DISEASES文献大全abstract:OBJECTIVE:The present study summarizes the current knowledge on the role of bacterial extracellular signaling systems, known as quorum sensing (QS), in oral biofilm formation, and on the possibility of blocking these microbial communication systems as a potential approach to prevent and treat oral infectious diseases. ...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.13689
更新日期:2020-10-20 00:00:00
abstract:OBJECTIVES:We determined the correlation between saliva and serum for CA125 and leptin, and evaluated their clinical screening potential for parotid tumours. SUBJECTS AND METHODS:Serum, acid-stimulated bilateral parotid saliva and chewing-stimulated whole saliva were collected and measured the levels of CA125 and lept...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12505
更新日期:2016-10-01 00:00:00
abstract::The aim of this article is to review the clinical, pathophysiological, and therapeutic aspects of traumatically induced trigeminal nerve pain. We introduce a new and, in our view, more accurate terminology: peripheral painful traumatic trigeminal neuropathy (PPTTN) to define this patient group. The proposed pathophysi...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1601-0825.2011.01883.x
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVES:Cyclosporine A (CsA) is used as an immunosuppressive agent and its prominent side effect is the induction of gingival overgrowth. Type I plasminogen activator inhibitor (PAI-1) has shown to play an important role in CsA-induced gingival overgrowth. However, little is known about whether factors can modulate ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2009.01653.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To investigate a possible role of adiponectin in the pathogenesis of autoimmune sialoadenitis in non-obese diabetic (NOD) mouse model of Sjögren's syndrome. MATERIALS AND METHODS:Expression of adiponectin and its receptors (AdipoR1/2) was detected by PCR, immunoblotting, or immunofluorescence. The level of a...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12197
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:To determine glucose transporter 1 (GLUT1) and runt-related transcription factor 2 (RUNX2) expression during reparative dentinogenesis after pulpotomy with mineral trioxide aggregate (MTA) capping. SUBJECTS AND METHODS:Eight-week-old male Wistar rats were used. Pulp of the upper left first molar was exposed...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13230
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:Salivary glands are useful target organs for local and systemic gene therapeutics. For such applications, the regulation of transgene expression is important. Previous studies by us in murine submandibular glands showed that a rapamycin transcriptional regulation system in a single serotype 2, adeno-associat...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2009.01631.x
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVES:To explore how various methylation mechanisms function and affect macrophages in periodontitis, with an aim of getting a comprehensive understanding of pathogenesis of the disease. SUBJECT:Alterations in DNA methylation are associated with different periodontitis susceptible factors and disrupt immunity hom...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13654
更新日期:2020-09-29 00:00:00
abstract:OBJECTIVES:This study aimed to analyse Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) viral loads in symptomatic and asymptomatic apical periodontitis lesions, to determine levels of TNF-α, IL-1β and IL-6 in these lesions and to investigate a possible correlation between herpesviral copy numbers and levels o...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12829
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:To assess the effects of periodontitis on renal interstitial fibrosis in a mouse model. MATERIALS AND METHODS:Thirty C57BL/6 male mice were divided into control, periodontitis (PD), unilateral ureteral ligation (UUO) and PD+UUO groups. Unilateral ureteral ligation was performed 6 days after periodontitis. A...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13764
更新日期:2020-12-31 00:00:00
abstract:OBJECTIVE:Orthodontic-induced external apical root resorption (EARR) is a complex phenotype determined by poorly defined mechanical and patient intrinsic factors. The aim of this work was to construct a multifactorial integrative model, including clinical and genetic susceptibility factors, to analyze the risk of devel...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12185
更新日期:2014-10-01 00:00:00
abstract::Oral Diseases (2011) 17, 252-257 Heme oxygenase (HO) system catabolizes heme into three products: carbon monoxide (CO), biliverdin/bilirubin and free iron, which consists of three forms identified to date: the oxidative stress-inducible protein HO-1 and the constitutive isozymes HO-2 and HO-3. HO has been involved in ...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1601-0825.2010.01732.x
更新日期:2011-04-01 00:00:00
abstract::The clinical presentation of oral lichen planus and oral lichenoid lesions is diverse. A special category of patients presents with lichenoid lesions affecting only the mucosa of their upper lip and the anterior upper gingiva. This is a concise review summarizing the specific characteristics of these patients. ...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.12763
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to determine whether the expression levels of specific circulating serum microRNAs (miRNAs) are associated with mandibular prognathism (MP). METHODS:Sixty subjects in the early permanent dentition stage and 23 in the mixed dentition stage with MP were identified. Sixty-eight normal ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12073
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To review a series of patients with sore, burning mouth treated with alpha-lipoic acid between 2000 and May 2006 and subjectively evaluate improvement in symptoms. DESIGN:Retrospective review of medical records of 195 consecutive patients who sought treatment for sore, burning mouth. Treatment of 47 patients...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2007.01414.x
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:This article sets out to evaluate the prevalence and aetiopathogenesis of edentulism in patients on haemodialysis. SUBJECTS AND METHODS:The study group comprised 44 adult patients with end-stage renal disease (ESRD) on haemodialysis. A control group was formed of 44 individuals matched for age and sex and wi...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12486
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:Up to 30% of multiple myeloma (MM) patients have subclinical amyloid deposits. These patients are under-recognized and are more susceptible to drug toxicity, bleeding and death. Early diagnosis and adjustment of treatment are crucial. Biopsies of oral mucosa might be a potentially useful diagnostic tool. The ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12901
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:This 6-month prospective clinical study assessed the impacts of Invisalign appliances on the oral bacterial community and oral health of patients. METHODS:Salivary samples were obtained from twenty-five adult patients receiving Invisalign aligner treatment before the treatment (Group B) and at a 6-month fol...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13175
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:Candida-induced denture stomatitis is a common debilitating problem among denture wearers. Previously, we described the fabrication of a new denture material that released antifungal drugs when immersed in phosphate buffered saline. Here, we use more clinically relevant immersion conditions (human saliva; 37°...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12456
更新日期:2016-07-01 00:00:00
abstract::Currently, 4 novel Direct Oral Anticoagulants (DOACs) were approved by the FDA. This review focuses on these agents and proposes a matrix for the general dentists to assess bleeding risk in dental management of patient on DOACs. The outline covers the pharmacology of DOACs (rivaroxaban, apixaban, edoxaban and dabigatr...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.12371
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:We aimed to investigate BRAF V600E percentage immunohistochemically in ameloblastomas of a single institute cohort. We were interested if age, location, histological properties, or tumor recurrence depend on the BRAF status. SUBJECTS, MATERIALS AND METHODS:We had 36 formalin-fixed, paraffin-embedded amelobl...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13072
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVES:It was hypothesized that beta 2 defensin (BD-2) is increased in RAU lesions compared with healthy controls to promote anti-microbial host defence. METHODS:RAU and control mucosa samples were subjected to quantitative real-time PCR and immunostained for BD-2, CD68, mast cell tryptase and 4-hydroxynonenal (4H...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12262
更新日期:2015-04-01 00:00:00
abstract::The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry,...
journal_title:Oral diseases
pub_type: 历史文章,杂志文章,评审
doi:10.1111/j.1601-0825.2009.01538.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:To evaluate the oral condition of alcohol and tobacco dependents and identify salivary protein candidates for biomarkers of oral disorders. SUBJECTS AND METHODS:Thirty-three male volunteers were evaluated for alcohol abuse rehabilitation; nine were selected for proteomic analysis. Intraoral examination was ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13337
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:Patients with burning mouth syndrome (BMS) often represent a clinical challenge as available agents for symptomatic treatment are few and often ineffective. The aim was to evaluate the effect of a bupivacaine lozenge on oral mucosal pain, xerostomia, and taste alterations in patients with BMS. METHODS:Eighte...
journal_title:Oral diseases
pub_type: 杂志文章,随机对照试验
doi:10.1111/odi.12386
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the erosive/abrasive enamel wear after contact with orange juices modified with different dietary supplements. METHODS:A total of 96 bovine enamel samples were prepared and allocated to eight groups (1-8; n = 12). Samples were eroded (120 s) in 200 ml of the following ei...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2011.01797.x
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:In this paper, we review the mechanisms thought to be involved in the activation of osteoclasts in periodontitis. SUMMARY:Osteoclasts are regulated by both microbial and host factors. Some factors act directly on cells of the osteoclast lineage, whereas others act indirectly through other cell types in the b...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1601-0825.1996.tb00218.x
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVE:Placenta growth factor (PlGF) is associated with the progression and prognosis of oral cancer. MATERIALS AND METHODS:This study used ELISA, quantitative polymerase chain reaction, and Western blotting to study the arecoline-stimulated (PlGF) protein or mRNA expression in human gingival epithelial S-G cells. ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12034
更新日期:2013-07-01 00:00:00
abstract::Submandibular gland excision is generally performed through a transcervical approach, a safe procedure that, however, carries few neurological, functional and aesthetic drawbacks. Intraoral approach to the submandibular gland has been described many years ago but it has been newly proposed in recent years thanks to en...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13340
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:To find out if strontium is incorporated into plaque and enamel in vivo during a 2-week rinsing period with a chlorhexidine-fluoride-strontium solution and to determine the effects of the rinsing on the numbers of mutans streptococci and lactobacilli in plaque. SUBJECTS AND METHODS:A total of 18 adult parti...
journal_title:Oral diseases
pub_type: 临床试验,杂志文章
doi:10.1111/j.1601-0825.1998.tb00267.x
更新日期:1998-06-01 00:00:00