Osteoclast activation in inflammatory periodontal diseases.

abstract：OBJECTIVE:Oral lichen planus is a chronic inflammatory oral mucosal disease whose exact cause is unclear and which requires efficient diagnostic and therapeutic strategies. Identification of disease-specific biomarkers in saliva is an easy, quick, and non-invasive approach for molecular diagnosis. This study was design...

journal_title：Oral diseases

authors： Byun JS,Hong SH,Choi JK,Jung JK,Lee HJ

更新日期：2015-11-01 00:00:00

abstract：:In order for chairside diagnostic testing to make an impact on dental therapy, practitioners require a better understanding of genetic mutations contributing to the pathophysiology of periodontal disease. Commensal and pathogenic bacterial colonization in oral cavity tissues produces a cascade of proinflammatory signa...

journal_title：Oral diseases

authors： Rudick CP,Lang MS,Miyamoto T

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:To examine seasonal variations in the presentation of acute necrotising ulcerative gingivitis (ANUG) in a previously unstudied population in Cape Town, South Africa. DESIGN:A descriptive study of all presenting cases of ANUG at a health center over 6 years; patients were examined at one point in time. SETT...

journal_title：Oral diseases

authors： Arendorf TM,Bredekamp B,Cloete CA,Joshipura K

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:To generate a nomogram for predicting the risk of neck node metastasis in pathologically node-negative patients using a combination of variables comprising of protein expression, ultrastructural alterations and clinicopathological parameters. MATERIALS AND METHODS:Surgically removed oral tumours (n = 103) we...

journal_title：Oral diseases

authors： Sawant SS,Dongre H,Ahire C,Sharma S,Kannan S,Mahadik S,Chaukar D,Lukmani F,Patil A,D'Cruz A,Vaidya MM,Dongre P

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Oral infection is considered to play a critical role in the pathogenesis of bisphosphonate-related osteonecrosis of the jaw (BRONJ), and antibiotic therapy has become a mainstay of BRONJ therapy. This study was aimed to investigate the effect of antibiotics on bacterial diversity in BRONJ tissues. MATERIALS ...

journal_title：Oral diseases

authors： Ji X,Pushalkar S,Li Y,Glickman R,Fleisher K,Saxena D

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Increasing evidence indicates that andrographolide (ADG) exhibits anti-cancer activity against various cancer cell lines. However, its high hydrophobicity and poor bioavailability restrict its clinical application as a chemopreventative agent. Previously, we have shown that ADG-loaded solid lipid nanoparticl...

journal_title：Oral diseases

authors： Li H,Qu X,Qian W,Song Y,Wang C,Liu W

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVE:Sodium lauryl sulphate (SLS), an important component in many oral health products, is well established as a contact irritant in skin. Recent studies have suggested that it may also affect the structural integrity of oral mucosa. SLS is rarely used alone in dentifrices or mouthwashes and the aim of this study ...

journal_title：Oral diseases

authors： Healy CM,Cruchley AT,Thornhill MH,Williams DM

更新日期：2000-03-01 00:00:00

abstract：:As the AIDS pandemic has continued, our understanding of the events that occur during the entry and infection of conventional, susceptible cells has increased dramatically, leading to the development of control therapies for HIV-infected individuals. However, an ongoing hole in our understanding is how HIV crosses the...

journal_title：Oral diseases

authors： Moyes DL,Islam A,Kohli A,Naglik JR

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Candida-induced denture stomatitis is a common debilitating problem among denture wearers. Previously, we described the fabrication of a new denture material that released antifungal drugs when immersed in phosphate buffered saline. Here, we use more clinically relevant immersion conditions (human saliva; 37°...

journal_title：Oral diseases

authors： Malakhov A,Wen J,Zhang BX,Wang H,Geng H,Chen XD,Sun Y,Yeh CK

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:An association between high-risk human papillomavirus (HR HPV) infection and a risk of development of a subgroup of head and neck cancers has been proposed recently. The main risk factors of oral and oropharyngal cancer observed in our population are smoking and alcohol consumption. The incidence of oral/orop...

journal_title：Oral diseases

authors： Tachezy R,Klozar J,Saláková M,Smith E,Turek L,Betka J,Kodet R,Hamsíková E

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVES:This systematic review was to evaluate the change of oral microbiome based on next-generation sequencing (NGS)-metagenomic analysis following periodontal interventions among systematically healthy subjects. MATERIALS AND METHODS:A structured search strategy consisting of "metagenomics" and "oral diseases" w...

journal_title：Oral diseases

authors： Zhang Y,Qi Y,Lo ECM,McGrath C,Mei ML,Dai R

更新日期：2020-05-11 00:00:00

abstract：:Periodontal tissues are constantly exposed to microbial stimuli. The equilibrium between microbes and host defense system helps maintain the homeostasis in the periodontal microenvironment. Growth of pathogenic bacteria in dental biofilms may induce proinflammatory cytokine production to recruit sentinel cells, mainly...

journal_title：Oral diseases

authors： Li J,Ke X,Yan F,Lei L,Li H

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:Cyclosporine A (CsA) is used as an immunosuppressive agent and its prominent side effect is the induction of gingival overgrowth. Type I plasminogen activator inhibitor (PAI-1) has shown to play an important role in CsA-induced gingival overgrowth. However, little is known about whether factors can modulate ...

journal_title：Oral diseases

authors： Ho YC,Lin HJ,Tsai CH,Chang YC

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine any association between anxiety and salivary cortisol levels in oral lichen planus (OLP) patients by the case-control method. DESIGN RELEVANT: Forty patients with OLP were evaluated. The OLP diagnosis was established through a composite of accepted clinical and histopath...

journal_title：Oral diseases

authors： Koray M,Dülger O,Ak G,Horasanli S,Uçok A,Tanyeri H,Badur S

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To conduct a systematic review and meta-analysis to evaluate the recent scientific literature addressing the association between periodontitis and asthma, chronic obstructive pulmonary disease (COPD), and pneumonia. MATERIALS AND METHODS:The search for studies was carried out using MEDLINE/PubMed, EMBASE, Li...

journal_title：Oral diseases

authors： Gomes-Filho IS,Cruz SSD,Trindade SC,Passos-Soares JS,Carvalho-Filho PC,Figueiredo ACMG,Lyrio AO,Hintz AM,Pereira MG,Scannapieco F

更新日期：2020-03-01 00:00:00

abstract：:It has been slightly more than a decade since the classic mechanistic paradigm that defined the pathogenesis of mucositis was revised. A five-stage sequence of linked biological events forms the basis for our current understanding of how regimen-related mucosal injury occurs. The first stage is the initiation phase, a...

journal_title：Oral diseases

authors： Sonis ST

更新日期：2010-10-01 00:00:00

abstract：:Analysis of the prevalence and incidence of HIV infection globally reveal striking variances with regard to continent, country, region and gender. Of the global total of 33 million people infected with HIV, approximately 65% are in sub-Saharan African countries and 15% in South and South-East Asia with the remaining 2...

journal_title：Oral diseases

authors： Challacombe SJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Radicular cysts occur as a result of the immunological response to continuous antigenic stimulation from root canals. We correlated the immunophenotypical composition of the lymphoid infiltrate to the microvessel density expressed by the count of CD34 reactive endothelial cells in radicular cysts. SUBJECTS A...

journal_title：Oral diseases

authors： Zizzi A,Aspriello SD,Ferrante L,Stramazzotti D,Colella G,Balercia P,Lo Muzio L,Piemontese M,Goteri G,Rubini C

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Opinions, knowledge, behaviours and attitudes of general dental practitioners on oral cancer prevention and detection have been reported from many countries. However, experiences and skills of oral cancer detection have not been evaluated systematically. OBJECTIVE:To obtain information on behaviours of scre...

journal_title：Oral diseases

authors： Seoane J,Warnakulasuriya S,Varela-Centelles P,Esparza G,Dios PD

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:To comparatively assess periodontal status in patients who chew different products and patients who do not have this habit and to assess how this practice interacts with predisposing factors and risk indicators of disease. METHODS:Patients included in the dental care carried out in a rural community in Indi...

journal_title：Oral diseases

authors： Giovannoni ML,Valdivia-Gandur I,Lozano de Luaces V,Varela Véliz H,Balasubbaiah Y,Chimenos-Küstner E

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:The traditional, biochemical and enzymatic methods of identifying Actinomyces species are frequently confounded by the similar phenotypic characteristics shared by the different members of this genus. Therefore, we developed novel species-specific oligonucleotide probes to accurately speciate seven pathogenic...

journal_title：Oral diseases

authors： Tang G,Yip HK,Luo G,Cheung BP,Shen S,Samaranayake LP

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Members of the family of matrix metalloproteinases (MMPs; also called collagenases or matrixins) are key enzymes in matrix degradation. They function at neutral pH and can digest synergistically all the matrix macromolecules. Biochemical and clonal studies indicate that there are three major groups: the spec...

journal_title：Oral diseases

authors： Reynolds JJ

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND: The value of chairside adjunctive tests in the detection of oral potentially malignant disorders (OPMDs) remains uncertain. OBJECTIVES: To determine the effectiveness of toluidine blue in detecting leukoplakia and erythroplakia and its accuracy in identifying cases with oral epithelial dysplasia. MATERIAL...

journal_title：Oral diseases

authors： Awan Kh,Yang Y,Morgan P,Warnakulasuriya S

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To analyze and compare periodontal parameters in chronic renal failure (CRF) patients undergoing peritoneal dialysis (PD) therapy with a group of patients on hemodialysis (HD) treatment and healthy controls (C). PARTICIPANTS:Seventy-five PD patients (mean age: 44 +/- 12 years) were matched with 41 HD patient...

journal_title：Oral diseases

authors： Bayraktar G,Kurtulus I,Kazancioglu R,Bayramgurler I,Cintan S,Bural C,Bozfakioglu S,Besler M,Trablus S,Issever H,Yildiz A

更新日期：2008-03-01 00:00:00

abstract：:Oral potentially malignant disorders (OPMDs) are associated with an increased risk of occurrence of cancers of the lip or oral cavity. This paper presents an updated report on the nomenclature and the classification of OPMDs, based predominantly on their clinical features, following discussions by an expert group at a...

journal_title：Oral diseases

authors： Warnakulasuriya S,Kujan O,Aguirre-Urizar JM,Bagan JV,González-Moles MÁ,Kerr AR,Lodi G,Mello FW,Monteiro L,Ogden GR,Sloan P,Johnson NW

更新日期：2020-10-31 00:00:00

abstract：BACKGROUND:Oral-facial-digital syndrome (OFDS) type 1 (OFD1) is an X-linked dominant condition associated with embryonic male lethality. It almost always affects the oral cavity, face, and digits. It is considered to be a ciliopathy caused by mutations in the OFD1 gene. A variety of mutations have been described, and a...

journal_title：Oral diseases

authors： Diz P,Alvarez-Iglesias V,Feijoo JF,Limeres J,Seoane J,Tomás I,Carracedo A

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To assess tissue characterization relating with neck metastasis of invasive tongue cancer, we investigate the usefulness of intra-oral ultrasonography (US). MATERIALS AND METHODS:The patients with squamous cell carcinoma of the tongue (n = 110) were preoperatively evaluated with intra-oral US. The US images ...

journal_title：Oral diseases

authors： Natori T,Koga M,Anegawa E,Nakashima Y,Tetsuka M,Yoh J,Kusukawa J

更新日期：2008-10-01 00:00:00

abstract：:The traditional concept of caries as a multifactorial transmittable and infectious disease has been challenged. Novel conceptual ideas have come to add to the complexity of this highly prevalent disease worldwide. Current etiological understanding of the disease has emphasized the pivotal role of sugars in caries. In ...

journal_title：Oral diseases

authors： Giacaman RA

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Subjects with cleft lip and palate (CLP) present high prevalence of dental agenesis. Among candidate genes for these phenotypes is IRF6. However, genetic studies do not analyze dental agenesis as a phenotype associated with cleft. Therefore, we investigated the frequency of rare and novel variations in IRF6 i...

journal_title：Oral diseases

authors： Neves LT,Dionísio TJ,Garbieri TF,Parisi VA,Oliveira FV,Oliveira TM,Santos CF

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:The present study was designed to investigate the effects of microRNA-21 (miR-21) on orthodontic tooth movement. METHODS:The orthodontic tooth movement model was established in C57BL/6 and miR-21-/- mice with or without implantation of activated T cells. Histological and histomorphometrical analyses were pe...

journal_title：Oral diseases

authors： Wu L,Su Y,Lin F,Zhu S,Wang J,Hou Y,Du J,Liu Y,Guo L

更新日期：2020-03-01 00:00:00