Regeneration of lingual musculature in rats using myoblasts over porcine bladder acellular matrix.

Abstract:

OBJECTIVES:To use tissue engineering muscle repair (TEMR) for regenerating the lingual musculature of hemiglossectomized rats using neonatal myoblasts (NM) on porcine acellular urinary bladder matrix (AUBM). MATERIAL AND METHODS:The study used 80 male rats. A volumetric muscle loss (VML) injury was created on the left side of the tongue. The rats were randomized into four groups: Group 1 (AUBM + myoblasts); Group 2 (AUBM); Group 3 (myoblasts); and Group 4 (control). NM were obtained from neonatal rats. The animals were weighed on day 0 and just before euthanasia. Five rats in each group were euthanized at days 2, 14, 28, and 42; the tongues were prepared for morphometric analysis, postoperative left hemitongue weight, and immunohistochemical analysis (desmin, CD-31, and anti-neurofilament). RESULTS:The weight gain from greatest to least was as follows: AUBM + myoblasts > myoblasts > AUBM > control. The tongue dorsum occupied by VML, and difference in mg between control side and intervened side from least to great was as follows: AUBM + myoblasts < myoblasts < AUBM < control. The order from highest to lowest antibody positivity was as follows: AUBM + myoblasts > myoblasts > AUBM > control. CONCLUSION:The use of porcine AUBM and NM for the regeneration of lingual musculature was found to be an effective TEMR treatment for repairing tongue VML injury.

journal_name

Oral Dis

journal_title

Oral diseases

authors

Camacho-Alonso F,García-Carrillo N,Buendía AJ,Navarro JA,Peñarrocha-Oltra D,Peñarrocha-Diago M,Lacal-Luján J

doi

10.1111/odi.13674

subject

Has Abstract

pub_date

2020-10-08 00:00:00

eissn

1354-523X

issn

1601-0825

pub_type

杂志文章
  • Oral colonization by Candida species in AIDS pediatric patients.

    abstract::The aim of this study was to assess the prevalence of factors associated with oral colonization by Candida spp. in pediatric patients with AIDS. The sample comprised of 117 children. Clinical status, medicines in use, and laboratory findings were obtained from hospital records; sociodemographic data were given by rela...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2010.01765.x

    authors: Domaneschi C,Massarente DB,de Freitas RS,de Sousa Marques HH,Paula CR,Migliari DA,Antunes JL

    更新日期:2011-05-01 00:00:00

  • T102C polymorphism of the 5-HT2A receptor gene may be associated with temporomandibular dysfunction.

    abstract:OBJECTIVE:To assess whether a relationship existed between the T102C polymorphism of 5-HT2A receptor gene and temporomandibular dysfunction. METHODS:Sixty-three patients with temporomandibular dysfunction, and 54 healthy volunteer controls were included in the study. Molecular analysis of the T102C polymorphism of the...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2004.01037.x

    authors: Mutlu N,Erdal ME,Herken H,Oz G,Bayazit YA

    更新日期:2004-11-01 00:00:00

  • Functional aspects of the human salivary cystatins in the oral environment.

    abstract:OBJECTIVES:The aim of this study was to investigate the cysteine protease inhibitory properties of the human salivary cystatins S, SA and SN in order to identify potential in vivo target cysteine proteases which may include those involved in periodontal tissue destruction. In addition, the potential role of the salivar...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.1999.tb00307.x

    authors: Baron A,DeCarlo A,Featherstone J

    更新日期:1999-07-01 00:00:00

  • Immune cellular profile of bisphosphonate-related osteonecrosis of the jaw.

    abstract:OBJECTIVES:Characterize the cell profile and immunostaining of proinflammatory markers in an experimental model of bisphosphonate-related osteonecrosis of the jaw (BRONJ). MATERIALS AND METHODS:Male Wistar rats (n = 6-7) were treated chronically with saline solution or zoledronic acid (ZA) at 0.04, 0.20, and 1.00 mg k...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12513

    authors: de Barros Silva PG,de Oliveira CC,Brizeno L,Wong D,Lima Júnior R,Gonçalves RP,Sousa FB,Mota M,de Albuquerque Ribeiro R,Alves A

    更新日期:2016-10-01 00:00:00

  • Associations of sleep bruxism with age, sleep apnea, and daytime problematic behaviors in children.

    abstract:OBJECTIVES:The aims of this study were to investigate the prevalence of sleep bruxism in children in Japan, and its relationships with sleep-related factors and daytime problematic behavior. SUBJECTS AND METHODS:Guardians of 6023 children aged 2-12 years completed the Japanese Sleep Questionnaire. Multiple regression ...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12492

    authors: Tachibana M,Kato T,Kato-Nishimura K,Matsuzawa S,Mohri I,Taniike M

    更新日期:2016-09-01 00:00:00

  • Inhibitory function of secretory leukocyte proteinase inhibitor (SLPI) in human saliva is HIV-1 specific and varies with virus tropism.

    abstract:OBJECTIVE:Secretory leukocyte proteinase inhibitor (SLPI) is an endogenous mucosa associated protein that has been proposed to possess anti-human immunodeficiency virus type 1 (HIV-1) activity. The aim of this study was to investigate the biological function of SLPI in salivary mediated inhibition of HIV infection and ...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1034/j.1601-0825.2002.01807.x

    authors: Skott P,Lucht E,Ehnlund M,Björling E

    更新日期:2002-05-01 00:00:00

  • Elder neglect-Oral diseases and injuries.

    abstract::Elder neglect (EN) is the failure of a designated caregiver to meet the needs of a dependent older person. World EN prevalence, meta-analyzed in this study, is 1.0% or 1.8% according to different statistical methods. Referring alleged EN cases to Adult Protective Services (APSs) by healthcare workers (HCWs) is mandato...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.12797

    authors: Petti S

    更新日期:2018-09-01 00:00:00

  • Clinical and genetic analysis of patients with cherubism.

    abstract:OBJECTIVE:To describe the clinical and genetic features of patients with cherubism. MATERIAL AND METHODS:A descriptive analysis of 14 cases from nine different families was carried out. Clinicopathological, imaging, and follow-up data were retrieved from patients' medical files and correlated with the genetic profile ...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12705

    authors: Machado RA,Pontes H,Pires FR,Silveira HM,Bufalino A,Carlos R,Tuji FM,Alves D,Santos-Silva AR,Lopes MA,Capistrano HM,Coletta RD,Fonseca FP

    更新日期:2017-11-01 00:00:00

  • Effect of a local anesthetic lozenge in relief of symptoms in burning mouth syndrome.

    abstract:OBJECTIVE:Patients with burning mouth syndrome (BMS) often represent a clinical challenge as available agents for symptomatic treatment are few and often ineffective. The aim was to evaluate the effect of a bupivacaine lozenge on oral mucosal pain, xerostomia, and taste alterations in patients with BMS. METHODS:Eighte...

    journal_title:Oral diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/odi.12386

    authors: Treldal C,Jacobsen CB,Mogensen S,Rasmussen M,Jacobsen J,Petersen J,Lynge Pedersen AM,Andersen O

    更新日期:2016-03-01 00:00:00

  • The effect of a sodium lauryl sulfate-free dentifrice on patients with recurrent oral ulceration.

    abstract:OBJECTIVE:Sodium lauryl sulphate (SLS) is the most commonly used detergent in dentifrices. Recent reports have suggested that it may exacerbate conditions with compromised epithelial integrity. The aim of this study was to compare the effect of an SLS-free dentifrice and an SLS-containing dentifrice on recurrent oral u...

    journal_title:Oral diseases

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1601-0825.1999.tb00062.x

    authors: Healy CM,Paterson M,Joyston-Bechal S,Williams DM,Thornhill MH

    更新日期:1999-01-01 00:00:00

  • Tooth ultrastructure of a novel COL1A2 mutation expanding its genotypic and phenotypic spectra.

    abstract:OBJECTIVES:To investigate tooth ultrastructure and mutation of two patients in a family affected with osteogenesis imperfecta (OI) type IV and dentinogenesis imperfecta (DGI). METHODS:Mutations were detected by whole exome and Sanger sequencing. The permanent second molar obtained from the proband (DGI1) and the prima...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13657

    authors: Intarak N,Budsamongkol T,Theerapanon T,Chanamuangkon T,Srijunbarl A,Boonprakong L,Porntaveetus T,Shotelersuk V

    更新日期:2020-09-29 00:00:00

  • Periodontitis aggravates renal inflammatory response in a mouse model of renal fibrosis.

    abstract:OBJECTIVES:To assess the effects of periodontitis on renal interstitial fibrosis in a mouse model. MATERIALS AND METHODS:Thirty C57BL/6 male mice were divided into control, periodontitis (PD), unilateral ureteral ligation (UUO) and PD+UUO groups. Unilateral ureteral ligation was performed 6 days after periodontitis. A...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13764

    authors: Bi C,Han XL,Li XZ,Sun JY,Liu Y,Duan SZ,Lu HX

    更新日期:2020-12-31 00:00:00

  • Toward gene therapy for growth hormone deficiency via salivary gland expression of growth hormone.

    abstract:OBJECTIVES:Salivary glands are useful targets for gene therapeutics. After gene transfer into salivary glands, regulated secretory pathway proteins, such as human growth hormone, are secreted into saliva, whereas constitutive secretory pathway proteins, such as erythropoietin, are secreted into the bloodstream. Secreti...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12217

    authors: Racz GZ,Zheng C,Goldsmith CM,Baum BJ,Cawley NX

    更新日期:2015-03-01 00:00:00

  • Peripheral painful traumatic trigeminal neuropathies.

    abstract::The aim of this article is to review the clinical, pathophysiological, and therapeutic aspects of traumatically induced trigeminal nerve pain. We introduce a new and, in our view, more accurate terminology: peripheral painful traumatic trigeminal neuropathy (PPTTN) to define this patient group. The proposed pathophysi...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.2011.01883.x

    authors: Benoliel R,Kahn J,Eliav E

    更新日期:2012-05-01 00:00:00

  • Periodontitis and respiratory diseases: A systematic review with meta-analysis.

    abstract:OBJECTIVE:To conduct a systematic review and meta-analysis to evaluate the recent scientific literature addressing the association between periodontitis and asthma, chronic obstructive pulmonary disease (COPD), and pneumonia. MATERIALS AND METHODS:The search for studies was carried out using MEDLINE/PubMed, EMBASE, Li...

    journal_title:Oral diseases

    pub_type: 杂志文章,meta分析

    doi:10.1111/odi.13228

    authors: Gomes-Filho IS,Cruz SSD,Trindade SC,Passos-Soares JS,Carvalho-Filho PC,Figueiredo ACMG,Lyrio AO,Hintz AM,Pereira MG,Scannapieco F

    更新日期:2020-03-01 00:00:00

  • Collagenases and tissue inhibitors of metalloproteinases: a functional balance in tissue degradation.

    abstract:BACKGROUND:Members of the family of matrix metalloproteinases (MMPs; also called collagenases or matrixins) are key enzymes in matrix degradation. They function at neutral pH and can digest synergistically all the matrix macromolecules. Biochemical and clonal studies indicate that there are three major groups: the spec...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.1996.tb00206.x

    authors: Reynolds JJ

    更新日期:1996-03-01 00:00:00

  • An update of knowledge on the regulatory role of Treg cells in apical periodontitis.

    abstract::Apical periodontitis (AP) is a prevalent infectious and inflammatory disorder that involves inflammation of periapical tissues and the disintegration of alveolar bone. AP may eventually lead to tooth loss if not timely treated. This disease is caused by pathogenic bacteria in the necrotic pulps and root canals, thereb...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.13450

    authors: Wei L,Xu M,Xiong H

    更新日期:2020-06-02 00:00:00

  • Proinflammatory cytokine levels in saliva before and after treatment of (erosive) oral lichen planus with dexamethasone.

    abstract:OBJECTIVE:To explore the potential of detecting the level of proinflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha), interleukin-1-alpha (IL-1-alpha), IL-6, and IL-8 in whole unstimulated saliva (WUS) in monitoring the therapeutic effects of topical dexamethasone on these salivary cytokines in subjects with...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2005.01165.x

    authors: Rhodus NL,Cheng B,Bowles W,Myers S,Miller L,Ondrey F

    更新日期:2006-03-01 00:00:00

  • Local drug delivery for oral mucosal diseases: challenges and opportunities.

    abstract::There are few topical formulations used for oral medicine applications most of which have been developed for the management of dermatological conditions. As such, numerous obstacles are faced when utilizing these preparations in the oral cavity, namely enzymatic degradation, taste, limited surface area, poor tissue pe...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.2011.01793.x

    authors: Sankar V,Hearnden V,Hull K,Juras DV,Greenberg MS,Kerr AR,Lockhart PB,Patton LL,Porter S,Thornhill M

    更新日期:2011-04-01 00:00:00

  • Latent transforming growth factor-β binding proteins (LTBP-1 and LTBP-2) and gingiva keratinization.

    abstract:OBJECTIVE:Transforming growth factor-beta (TGF-β) proteins are involved in epithelial keratinization. The major function of latent TGF-β binding proteins (LTBPs) is modulating TGF-β activity. However, whether LTBP-1 and LTBP-2 play roles in gingiva keratinization remains unclear. MATERIALS AND METHODS:Human keratinize...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12344

    authors: Chiang MS,Yang JR,Liao SC,Hsu CC,Hsu CW,Yuan K

    更新日期:2015-09-01 00:00:00

  • RT-PCR quantification of periodontal pathogens in crack users and non-users.

    abstract:OBJECTIVE:To compare counts of Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Porphyromonas gingivalis and Fusobacterium nucleatum between crack users and non-users. MATERIALS AND METHODS:A cross-sectional study was conducted involving seventy-four crack cocaine users and eighty-one non-users matched fo...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12609

    authors: Casarin M,Antoniazzi RP,Vaucher RA,Feldens CA,Zanatta FB

    更新日期:2017-04-01 00:00:00

  • Is the YouTube™ an useful source of information on oral leukoplakia?

    abstract:OBJECTIVES:YouTube™ has become a widely used source of health information. This cross-sectional study aimed to analyze the quality of English language videos on oral leukoplakia available on YouTube™. MATERIALS AND METHODS:A YouTube™ search for oral leukoplakia was performed, leading to 1,690 videos. The first 100 res...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13161

    authors: Kovalski LNS,Cardoso FB,D'Avila OP,Corrêa APB,Martins MAT,Martins MD,Carrard VC

    更新日期:2019-11-01 00:00:00

  • Fatty acid synthase expression in squamous cell carcinoma of the tongue: clinicopathological findings.

    abstract:BACKGROUND:Overexpression of fatty acid synthase (FAS), the cytosolic enzyme responsible for the conversion of dietary carbohydrates to fatty acids, has been reported in several human malignancies and pointed as a potential prognostic marker for some tumors. This study investigated whether FAS immunohistochemical expre...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2007.01395.x

    authors: Silva SD,Perez DE,Nishimoto IN,Alves FA,Pinto CA,Kowalski LP,Graner E

    更新日期:2008-05-01 00:00:00

  • Effect of aluminum concentration on dental caries formation in the rat.

    abstract:OBJECTIVE:Topically applied aluminum (AI) reduced fissure caries in rats with indigenous microflora, but neither therapeutic activity nor concentration effects have been studied in animals infected with caries-inducing bacteria. This study investigated the effects of solutions containing various AI concentrations on fo...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.1995.tb00164.x

    authors: Putt MS,Kleber CJ

    更新日期:1995-06-01 00:00:00

  • Increased expression of TRPV1 in squamous cell carcinoma of the human tongue.

    abstract:OBJECTIVES:Recent reports have unambiguously identified the presence and the growth-modulatory role of transient receptor potential vanilloid-1 (TRPV1), a central integrator of pain sensation, on numerous non-neuronal cell types and, of great importance, in certain malignancies. In this study, we have investigated the ...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2009.01526.x

    authors: Marincsák R,Tóth BI,Czifra G,Márton I,Rédl P,Tar I,Tóth L,Kovács L,Bíró T

    更新日期:2009-07-01 00:00:00

  • The homeobox HOXB13 is expressed in human minor salivary gland.

    abstract:BACKGROUND:Homeobox are a family of developmental genes involved in morphogenesis and cellular differentiation. Participation of homeobox within normal and malignant tissue has been recently discussed in the literature. OBJECTIVE:To analyze the presence of HOXB13 transcript expression in human minor salivary gland. M...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2005.01218.x

    authors: Cazal C,Sobral AP,de Almeida FC,das Graças Silva-Valenzuela M,Durazzo MD,Nunes FD

    更新日期:2006-07-01 00:00:00

  • Oral lichen planus: controversies surrounding malignant transformation.

    abstract::Studies of the malignant potential of oral lichen planus (OLP) have been hampered by inconsistencies in the diagnostic criteria used for OLP, the criteria adopted to identify a true case of malignant transformation in OLP, the risk factors for malignant transformation and the optimum management of patients to ensure t...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.2008.01441.x

    authors: Gonzalez-Moles MA,Scully C,Gil-Montoya JA

    更新日期:2008-04-01 00:00:00

  • HPV and other risk factors of oral cavity/oropharyngeal cancer in the Czech Republic.

    abstract:OBJECTIVE:An association between high-risk human papillomavirus (HR HPV) infection and a risk of development of a subgroup of head and neck cancers has been proposed recently. The main risk factors of oral and oropharyngal cancer observed in our population are smoking and alcohol consumption. The incidence of oral/orop...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2005.01112.x

    authors: Tachezy R,Klozar J,Saláková M,Smith E,Turek L,Betka J,Kodet R,Hamsíková E

    更新日期:2005-05-01 00:00:00

  • Osteomyelitis, osteoradionecrosis, or medication-related osteonecrosis of the jaws? Can CBCT enhance radiographic diagnosis?

    abstract:OBJECTIVE:To attempt defining differential radiographic diagnostic characteristics for osteonecrotic lesions using 2D as opposed to 3D images. MATERIALS AND METHODS:This was a cross-sectional study. Subjects presenting mandibular osteonecrotic lesions (osteomyelitis, osteoradionecrosis, and medication-related osteonec...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13534

    authors: Gaêta-Araujo H,Vanderhaeghen O,Vasconcelos KF,Coucke W,Coropciuc R,Politis C,Jacobs R

    更新日期:2021-03-01 00:00:00

  • Age-related dental phenotypes and tooth characteristics of FAM83H-associated hypocalcified amelogenesis imperfect.

    abstract:OBJECTIVES:Autosomal-dominant hypocalcified amelogenesis imperfecta (ADHCAI) shows phenotypic heterogeneity. Our aim was to characterise the ADHCAI phenotypes, tooth properties and genotypes. METHODS:Three unrelated ADHCAI probands and seven additional affected members of the three families were recruited. Mutations w...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13780

    authors: Sriwattanapong K,Nitayavardhana I,Theerapanon T,Thaweesapphithak S,Chantarawaratit PO,Garuyakich R,Phokaew C,Porntaveetus T,Shotelersuk V

    更新日期:2021-01-24 00:00:00